Expression of Abl interactor 1 and its prognostic significance in breast cancer: A tissue-array-based investigation

Breast Cancer Research and Treatment

Volumn 129, Issue 2, 2011, Pages 373-386

  Wang, Chunjie ^a,b   Tran Thanh, Danh ^b,c   Moreno, Juan C ^b   Cawthorn, Thomas R ^b,d   Jacks, Lindsay M ^c   Wang, Dong Yu ^b   McCready, David R ^c   Done, Susan J ^b,c,d  

^a UNIVERSITY OF MANITOBA   (Canada)

^b PRINCESS MARGARET HOSPITAL   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

Abl interactor 1; Biomarker; Breast cancer; Immunohistochemistry; Prognosis

Indexed keywords

ABL INTERACTOR 1; ADAPTOR PROTEIN; ANTINEOPLASTIC AGENT; HORMONE; KI 67 ANTIGEN; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ADULT; AGE DISTRIBUTION; ARTICLE; BREAST CANCER; BREAST CARCINOMA; CANCER INVASION; CANCER PATIENT; CANCER RECURRENCE; CANCER SURVIVAL; CONTROLLED STUDY; DISEASE FREE SURVIVAL; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; TISSUE MICROARRAY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AGE FACTORS; BREAST NEOPLASMS; CHI-SQUARE DISTRIBUTION; CYTOSKELETAL PROTEINS; DISEASE-FREE SURVIVAL; FEMALE; GENE EXPRESSION PROFILING; HUMANS; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIER ESTIMATE; MIDDLE AGED; NEOPLASM INVASIVENESS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOSPHORYLATION; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PROTO-ONCOGENE PROTEINS C-AKT; RISK ASSESSMENT; RISK FACTORS; SURVIVAL RATE; TIME FACTORS; TISSUE ARRAY ANALYSIS; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

EID: 80052626627     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-010-1241-0     Document Type: Article

References (51)

1. LM Machesky 2008 Lamellipodia and filopodia in metastasis and invasion FEBS Lett 582 2102 2111 18396168 10.1016/j.febslet.2008.03.039 1:CAS:528:DC%2BD1cXms1WgtLc%3D
2. TE Stradal G Scita 2006 Protein complexes regulating Arp2/3-mediated actin assembly Curr Opin Cell Biol 18 4 10 16343889 10.1016/j.ceb.2005.12.003 1:CAS:528:DC%2BD28XmsVGqsQ%3D%3D (Pubitemid 43107601)
3. M Innocenti A Zucconi A Disanza, et al. 2004 Abi1 is essential for the formation and activation of a WAVE2 signalling complex Nat Cell Biol 6 319 327 15048123 10.1038/ncb1105 1:CAS:528:DC%2BD2cXis1GltL0%3D (Pubitemid 38584821)
4. TE Stradal K Rottner A Disanza, et al. 2004 Regulation of actin dynamics by WASP and WAVE family proteins Trends Cell Biol 14 303 311 15183187 10.1016/j.tcb.2004.04.007 1:CAS:528:DC%2BD2cXks1ertbc%3D (Pubitemid 38798179)
5. M Innocenti E Frittoli I Ponzanelli, et al. 2003 Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1 J Cell Biol 160 17 23 12515821 10.1083/jcb.200206079 1:CAS:528: DC%2BD3sXjslWnsQ%3D%3D (Pubitemid 36091713)
6. K Eto H Nishikii T Ogaeri, et al. 2007 The WAVE2/Abi1 complex differentially regulates megakaryocyte development and spreading: implications for platelet biogenesis and spreading machinery Blood 110 3637 3647 17664349 10.1182/blood-2007-04-085860 1:CAS:528:DC%2BD2sXhtlarurrL (Pubitemid 350159632)
7. WA Kheir JC Gevrey H Yamaguchi, et al. 2005 A WAVE2-Abi1 complex mediates CSF-1-induced F-actin-rich membrane protrusions and migration in macrophages J Cell Sci 118 5369 5379 16280551 10.1242/jcs.02638 1:CAS:528:DC%2BD2MXhtlWru7vL (Pubitemid 41819598)
8. Y Leng J Zhang K Badour, et al. 2005 Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation Proc Natl Acad Sci USA 102 1098 1103 15657136 10.1073/pnas.0409120102 1:CAS:528:DC%2BD2MXhtFCitr4%3D (Pubitemid 40170732)
9. Y Shi K Alin SP Goff 1995 Abl-interactor-1, a novel SH3 protein binding to the carboxy-terminal portion of the Abl protein, suppresses v-abl transforming activity Genes Dev 9 2583 2597 7590237 10.1101/gad.9.21.2583 1:CAS:528:DyaK2MXpt1OhtL0%3D
10. Z Biesova C Piccoli WT Wong 1997 Isolation and characterization of e3B1, an eps8 binding protein that regulates cell growth Oncogene 14 233 241 9010225 10.1038/sj.onc.1200822 1:CAS:528:DyaK2sXnsFChsg%3D%3D (Pubitemid 27068309)
11. S Kakiuchi Y Daigo T Tsunoda, et al. 2003 Genome-wide analysis of organ-preferential metastasis of human small cell lung cancer in mice Mol Cancer Res 1 485 499 12754296 1:CAS:528:DC%2BD3sXjvVSltL0%3D (Pubitemid 36577045)
12. Z Duan DE Lamendola Y Duan, et al. 2005 Description of paclitaxel resistance-associated genes in ovarian and breast cancer cell lines Cancer Chemother Pharmacol 55 277 285 15565326 10.1007/s00280-004-0878-y 1:CAS:528:DC%2BD2MXhtVCnug%3D%3D (Pubitemid 40142893)
13. Z Dai AM Pendergast 1995 Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity Genes Dev 9 2569 2582 7590236 10.1101/gad.9.21.2569 1:CAS:528:DyaK2MXpt1OhtLw%3D
14. Y Funato T Terabayashi N Suenaga, et al. 2004 IRSp53/Eps8 complex is important for positive regulation of Rac and cancer cell motility/invasiveness Cancer Res 64 5237 5244 15289329 10.1158/0008-5472.CAN-04-0327 1:CAS:528:DC%2BD2cXmtF2mtbs%3D (Pubitemid 39006543)
15. JA Macoska J Xu D Ziemnicka, et al. 2001 Loss of expression of human spectrin src homology domain binding protein 1 is associated with 10p loss in human prostatic adenocarcinoma Neoplasia 3 99 104 11420744 10.1038/sj.neo. 7900145 1:CAS:528:DC%2BD3MXjvVeqsrk%3D (Pubitemid 32410349)
16. Cui M, Yu W, Dong J et al (2009) Downregulation of ABI1 expression affects the progression and prognosis of human gastric carcinoma. Med Oncol 27:632-639
17. J Xu D Ziemnicka GS Merz, et al. 2000 Human spectrin Src homology 3 domain binding protein 1 regulates macropinocytosis in NIH 3T3 cells J Cell Sci 113 Pt 21 3805 3814 11034908 1:STN:280:DC%2BD3M%2FptVCmsg%3D%3D
18. C Wang R Navab V Iakovlev, et al. 2007 Abelson interactor protein-1 positively regulates breast cancer cell proliferation, migration, and invasion Mol Cancer Res 5 1031 1039 17951403 10.1158/1541-7786.MCR-06-0391 1:CAS:528:DC%2BD2sXhtFygsLvJ (Pubitemid 350070758)
19. X Sun C Li C Zhuang, et al. 2009 Abl interactor 1 regulates Src-Id1-matrix metalloproteinase 9 axis and is required for invadopodia formation, extracellular matrix degradation and tumor growth of human breast cancer cells Carcinogenesis 30 2109 2116 19843640 10.1093/carcin/bgp251 1:CAS:528:DC%2BD1MXhsFGhur3M
20. V Stambolic JR Woodgett 2006 Functional distinctions of protein kinase B/Akt isoforms defined by their influence on cell migration Trends Cell Biol 16 461 466 16870447 10.1016/j.tcb.2006.07.001 1:CAS:528:DC%2BD28XptFChsbg%3D (Pubitemid 44293397)
21. RM Katso OE Pardo A Palamidessi, et al. 2006 Phosphoinositide 3-kinase C2beta regulates cytoskeletal organization and cell migration via Rac-dependent mechanisms Mol Biol Cell 17 3729 3744 16775008 10.1091/mbc.E05-11-1083 1:CAS:528:DC%2BD28Xpt1altbc%3D (Pubitemid 44330861)
22. M Nishita Y Wang C Tomizawa, et al. 2004 Phosphoinositide 3-kinase-mediated activation of cofilin phosphatase Slingshot and its role for insulin-induced membrane protrusion J Biol Chem 279 7193 7198 14645219 10.1074/jbc.M312591200 1:CAS:528:DC%2BD2cXht1Cksb0%3D (Pubitemid 38248866)
23. V Stambolic A Suzuki JL de la Pompa, et al. 1998 Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN Cell 95 29 39 9778245 10.1016/S0092-8674(00)81780-8 1:CAS:528:DyaK1cXmslWlsr0%3D (Pubitemid 28458022)
24. S Brader SA Eccles 2004 Phosphoinositide 3-kinase signalling pathways in tumor progression, invasion and angiogenesis Tumori 90 2 8 15143962 1:CAS:528:DC%2BD2cXkvVakur8%3D (Pubitemid 38541717)
25. MC Cheang SK Chia D Voduc, et al. 2009 Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer J Natl Cancer Inst 101 736 750 19436038 10.1093/jnci/djp082 1:CAS:528:DC%2BD1MXmtlyit74%3D
26. J Hugh J Hanson MC Cheang, et al. 2009 Breast cancer subtypes and response to docetaxel in node-positive breast cancer: use of an immunohistochemical definition in the BCIRG 001 trial J Clin Oncol 27 1168 1176 19204205 10.1200/JCO.2008.18.1024 1:CAS:528:DC%2BD1MXktFKhs7Y%3D
27. AC Wolff ME Hammond JN Schwartz, et al. 2007 American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer J Clin Oncol 25 118 145 17159189 10.1200/JCO.2006.09.2775 1:CAS:528:DC%2BD2sXht1ejs7Y%3D (Pubitemid 350003059)
28. ME Hammond DF Hayes M Dowsett, et al. 2010 American Society of Clinical Oncology/College Of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer J Clin Oncol 28 2784 2795 20404251 10.1200/JCO.2009.25.6529
29. MJ van de Vijver YD He LJ van't Veer, et al. 2002 A gene-expression signature as a predictor of survival in breast cancer N Engl J Med 347 1999 2009 12490681 10.1056/NEJMoa021967 (Pubitemid 35461656)
30. LM McShane DG Altman W Sauerbrei, et al. 2005 Reporting recommendations for tumor marker prognostic studies (REMARK) J Natl Cancer Inst 97 1180 1184 16106022 10.1093/jnci/dji237 1:CAS:528:DC%2BD2MXpsVaks7s%3D (Pubitemid 41258223)
31. JR Ryu A Echarri R Li, et al. 2009 Regulation of cell-cell adhesion by Abi/Diaphanous complexes Mol Cell Biol 29 1735 1748 19158278 10.1128/MCB.01483-08 1:CAS:528:DC%2BD1MXjs1Wqtr0%3D
32. S Liebau B Vaida C Proepper, et al. 2007 Formation of cellular projections in neural progenitor cells depends on SK3 channel activity J Neurochem 101 1338 1350 17459146 10.1111/j.1471-4159.2006.04437.x 1:CAS:528:DC%2BD2sXmsFensLo%3D (Pubitemid 46718816)
33. D Yamazaki T Oikawa T Takenawa 2007 Rac-WAVE-mediated actin reorganization is required for organization and maintenance of cell-cell adhesion J Cell Sci 120 86 100 17164293 10.1242/jcs.03311 1:CAS:528: DC%2BD2sXht1GmsL0%3D (Pubitemid 46206652)
34. C Proepper S Johannsen S Liebau, et al. 2007 Abelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formation EMBO J 26 1397 1409 17304222 10.1038/sj.emboj.7601569 1:CAS:528:DC%2BD2sXisVKru78%3D (Pubitemid 46398696)
35. Y Wu H Mohamed R Chillar, et al. 2008 Clinical significance of Akt and HER2/neu overexpression in African-American and Latina women with breast cancer Breast Cancer Res 10 R3 18184439 10.1186/bcr1844
36. E Tokunaga Y Kimura E Oki, et al. 2006 Akt is frequently activated in HER2/neu-positive breast cancers and associated with poor prognosis among hormone-treated patients Int J Cancer 118 284 289 16049961 10.1002/ijc.21358 1:CAS:528:DC%2BD2MXhtlWqs7fP (Pubitemid 41779066)
37. CM Perou T Sorlie MB Eisen, et al. 2000 Molecular portraits of human breast tumours Nature 406 747 752 10963602 10.1038/35021093 1:CAS:528: DC%2BD3cXmt1CnsLw%3D
38. T Sorlie CM Perou R Tibshirani, et al. 2001 Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications Proc Natl Acad Sci USA 98 10869 10874 11553815 10.1073/pnas.191367098 1:CAS:528:DC%2BD3MXntVGmsbo%3D (Pubitemid 32878711)
39. LJ van 't Veer H Dai MJ van de Vijver, et al. 2002 Gene expression profiling predicts clinical outcome of breast cancer Nature 415 530 536 11823860 10.1038/415530a (Pubitemid 34130608)
40. HY Chang JB Sneddon AA Alizadeh, et al. 2004 Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds PLoS Biol 2 E7 10.1371/journal.pbio.0020007 14737219 10.1371/journal.pbio.0020007 (Pubitemid 39234559)
41. LC Kelley S Shahab SA Weed 2008 Actin cytoskeletal mediators of motility and invasion amplified and overexpressed in head and neck cancer Clin Exp Metastasis 25 289 304 18324357 10.1007/s10585-008-9154-6 1:CAS:528: DC%2BD1cXptVSqu7w%3D
42. BL Rothschild AH Shim AG Ammer, et al. 2006 Cortactin overexpression regulates actin-related protein 2/3 complex activity, motility, and invasion in carcinomas with chromosome 11q13 amplification Cancer Res 66 8017 8025 16912177 10.1158/0008-5472.CAN-05-4490 1:CAS:528:DC%2BD28XotFWqt7o%3D (Pubitemid 44299166)
43. Yu W, Sun X, Clough N et al (2008) Abi1 gene silencing by short hairpin RNA impairs Bcr-Abl-induced cell adhesion and migration in vitro and leukemogenesis in vivo. Carcinogenesis 29:1717-1724
44. SY Liu F Wu YM Tao, et al. 2009 Increased expression of Abi1 in hepatocellular carcinoma and its correlation with poor prognosis of hepatocellular carcinoma Zhonghua Wai Ke Za Zhi 47 1732 1735 20137729
45. JM Silva E Ezhkova J Silva, et al. 2009 Cyfip1 is a putative invasion suppressor in epithelial cancers Cell 137 1047 1061 19524508 10.1016/j.cell.2009.04.013 1:CAS:528:DC%2BD1MXps1eiurc%3D
46. Z Dai RC Quackenbush KD Courtney, et al. 1998 Oncogenic Abl and Src tyrosine kinases elicit the ubiquitin-dependent degradation of target proteins through a Ras-independent pathway Genes Dev 12 1415 1424 9585502 10.1101/gad.12.10.1415 1:CAS:528:DyaK1cXjtlKkur8%3D (Pubitemid 28243627)
47. SB Vestey C Sen CJ Calder, et al. 2005 Activated Akt expression in breast cancer: correlation with p53, Hdm2 and patient outcome Eur J Cancer 41 1017 1025 15862750 10.1016/j.ejca.2005.02.011 1:CAS:528:DC%2BD2MXjs1Crtb4%3D (Pubitemid 40602853)
48. S Bose S Chandran JM Mirocha, et al. 2006 The Akt pathway in human breast cancer: a tissue-array-based analysis Mod Pathol 19 238 245 16341149 10.1038/modpathol.3800525 1:CAS:528:DC%2BD28Xlt1eqsA%3D%3D (Pubitemid 43117608)
49. G Perez-Tenorio O Stal Southeast Sweden Breast Cancer Group 2002 Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients Br J Cancer 86 540 545 11870534 10.1038/sj.bjc.6600126 1:CAS:528:DC%2BD38XislCmtro%3D (Pubitemid 34185089)
50. MH Galea RW Blamey CE Elston, et al. 1992 The Nottingham Prognostic Index in primary breast cancer Breast Cancer Res Treat 22 207 219 1391987 10.1007/BF01840834 1:STN:280:DyaK3s%2FgsVyisA%3D%3D
51. P Eifel JA Axelson J Costa, et al. 2001 National Institutes of Health Consensus Development Conference Statement: adjuvant therapy for breast cancer, November 1-3, 2000 J Natl Cancer Inst 93 979 989 11438563 10.1093/jnci/93.13.979 1:STN:280:DC%2BD3MzpvFamtA%3D%3D