Type 1 interferon induction of natural killer cell gamma interferon production for defense during lymphocytic choriomeningitis virus infection

mBio

Volumn 2, Issue 4, 2011, Pages

  Mack, Ethan A ^a   Kallal, Lara E ^a   Demers, Delia A ^a   Biron, Christine A ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; INTERFERON; INTERFERON RECEPTOR; STAT1 PROTEIN; STAT4 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MOUSE; NATURAL KILLER CELL; NONHUMAN; PERITONEAL CAVITY; PERITONEUM EXUDATE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; VIRUS INFECTION;

LYMPHOCYTIC CHORIOMENINGITIS VIRUS;

EID: 80052576934     PISSN: None     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.00169-11     Document Type: Article

References (46)

1. Biron CA, Nguyen KB, Pien GC, Cousens LP, Salazar-Mather TP. 1999. Natural killer cells in antiviral defense: function and regulation by innate cytokines. Annu. Rev. Immunol. 17:189-220.
2. Lee SH, Biron CA. 2010. Here today-not gone tomorrow: roles for activating receptors in sustaining NK cells during viral infections. Eur. J. Immunol. 40:923-932.
3. Orange JS, Biron CA. 1996. Characterization of early IL-12, IFNalphabeta, and TNF effects on antiviral state and NK cell responses during murine cytomegalovirus infection. J. Immunol. 156:4746-4756.
4. Nguyen KB, et al. 2002. Coordinated and distinct roles for IFN-alpha beta, IL-12, and IL-15 regulation of NK cell responses to viral infection. J. Immunol. 169:4279-4287.
5. García-Sastre A, Biron CA. 2006. Type 1 interferons and the virus-host relationship: a lesson in detente. Science 312:879-882.
6. Nguyen KB, et al. 2000. Interferon alpha/beta-mediated inhibition and promotion of interferon gamma: STAT1 resolves a paradox. Nat. Immunol. 1:70-76.
7. Pien GC, Nguyen KB, Malmgaard L, Satoskar AR, Biron CA. 2002. A unique mechanism for innate cytokine promotion of T cell responses to viral infections. J. Immunol. 169:5827-5837.
8. Orange JS, Biron CA. 1996. An absolute and restricted requirement for IL-12 in natural killer cell IFN-gamma production and antiviral defense. Studies of natural killer and T cell responses in contrasting viral infections. J. Immunol. 156:1138-1142.
9. Miyagi T, et al. 2007. High basal STAT4 balanced by STAT1 induction to control type 1 interferon effects in natural killer cells. J. Exp. Med. 204: 2383-2396.
10. Platanias LC. 2005. Mechanisms of type-I- and type-II-interferonmediated signalling. Nat. Rev. Immunol. 5:375-386.
11. Lee CK, et al. 2000. Distinct requirements for IFNs and STAT1 in NK cell function. J. Immunol. 165:3571-3577.
12. Brierley MM, Fish EN. 2002. Review: IFN-alpha/beta receptor interactions to biologic outcomes: understanding the circuitry. J. Interferon Cytokine Res. 22:835-845.
13. Kaplan MH, Sun YL, Hoey T, Grusby MJ. 1996. Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. Nature 382:174-177.
14. Rogge L, et al. 1998. The role of Stat4 in species-specific regulation of Th cell development by type I IFNs. J. Immunol. 161:6567-6574.
15. Nguyen KB, et al. 2002. Critical role for STAT4 activation by type 1 interferons in the interferon-gamma response to viral infection. Science 297:2063-2066.
16. Cousens LP, et al. 1999. Two roads diverged: interferon alpha/beta- and interleukin 12-mediated pathways in promoting T cell interferon gamma responses during viral infection. J. Exp. Med. 189:1315-1328.
17. Louten J, van Rooijen N, Biron CA. 2006. Type 1 IFN deficiency in the absence of normal splenic architecture during lymphocytic choriomeningitis virus infection. J. Immunol. 177:3266-3272.
18. Barton LL, Mets MB. 2001. Congenital lymphocytic choriomeningitis virus infection: decade of rediscovery. Clin. Infect. Dis. 33:370-374.
19. Fischer SA, et al. 2006. Transmission of lymphocytic choriomeningitis virus by organ transplantation. N. Engl. J. Med. 354:2235-2249.
20. Palacios G, et al. 2008. A new arenavirus in a cluster of fatal transplantassociated diseases. N. Engl. J. Med. 358:991-998.
21. Wysocka M, et al. 1995. Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice. Eur. J. Immunol. 25:672-676.
22. Nguyen KB, Biron CA. 1999. Synergism for cytokine-mediated diseaseduring concurrent endotoxin and viral challenges: roles for NK and T cell IFN-gamma production. J. Immunol. 162:5238-5246.
23. Sheehan KC, et al. 2006. Blocking monoclonal antibodies specific for mouse IFN-alpha/beta receptor subunit 1 (IFNAR-1) from mice immunized by in vivo hydrodynamic transfection. J. Interferon Cytokine Res. 26:804-819.
24. Müller U, et al. 1994. Functional role of type I and type II interferons in antiviral defense. Science 264:1918-1921.
25. Huang S, et al. 1993. Immune response in mice that lack the interferongamma receptor. Science 259:1742-1745.
26. Wong LH, et al. 2002. Isolation and characterization of a human STAT1 gene regulatory element. Inducibility by interferon (IFN) types I and II and role of IFN regulatory factor-1. J. Biol. Chem. 277:19408-19417.
27. van Boxel-Dezaire AH, et al. 2010. Major differences in the responses of primary human leukocyte subsets to IFN-beta. J. Immunol. 185: 5888-5899.
28. Zhou H, Zhao J, Perlman S. 2010. Autocrine interferon priming in macrophages but not dendritic cells results in enhanced cytokine and chemokine production after coronavirus infection. Mbio 1(4):e00219-10.
29. Miyagi T, et al. 2010. Altered interferon-alpha-signaling in natural killer cells from patients with chronic hepatitis C virus infection. J. Hepatol. 53:424-430.
30. Martinez J, Huang X, Yang Y. 2008. Direct action of type I IFN on NK cells is required for their activation in response to vaccinia viral infection in vivo. J. Immunol. 180:1592-1597.
31. Malmgaard L, Paludan SR. 2003. Interferon (IFN)-alpha/beta, interleukin (IL)-12 and IL-18 coordinately induce production of IFN-gamma during infection with herpes simplex virus type 2. J. Gen. Virol. 84: 2497-2500.
32. + Th1 immunity with poly IC as adjuvant. J. Exp. Med. 206:1589-1602.
33. McCartney S, et al. 2009. Distinct and complementary functions of MDA5 and TLR3 in poly(I:C)-mediated activation of mouse NK cells. J. Exp. Med. 206:2967-2976.
34. Berenson LS, Farrar JD, Murphy TL, Murphy KM. 2004. Frontline: absence of functional STAT4 activation despite detectable tyrosine phosphorylation induced by murine IFN-alpha. Eur. J. Immunol. 34: 2365-2374.
35. Micallef MJ, et al. 1996. Interferon-gamma-inducing factor enhances T helper 1 cytokine production by stimulated human T cells: synergism with interleukin-12 for interferon-gamma production. Eur. J. Immunol. 26: 1647-1651.
36. Sareneva T, Matikainen S, Kurimoto M, Julkunen I. 1998. Influenza A virus-induced IFN-alpha/beta and IL-18 synergistically enhance IFNgamma gene expression in human T cells. J. Immunol. 160:6032-6038.
37. Matikainen S, et al. 2001. IFN-alpha and IL-18 synergistically enhance IFN-gamma production in human NK cells: differential regulation of Stat4 activation and IFN-gamma gene expression by IFN-alpha and IL-12. Eur. J. Immunol. 31:2236-2245.
38. Perrot I, et al. 2010. TLR3 and Rig-like receptor on myeloid dendritic cells and Rig-like receptor on human NK cells are both mandatory for production of IFN-gamma in response to double-stranded RNA. J. Immunol. 185:2080-2088.
39. Toshchakov V, et al. 2002. TLR4, but not TLR2, mediates IFN-betainduced STAT1alpha/beta-dependent gene expression in macrophages. Nat. Immunol. 3:392-398.
40. Bukowski JF, Woda BA, Habu S, Okumura K, Welsh RM. 1983. Natural killer cell depletion enhances virus synthesis and virus-induced hepatitis in vivo. J. Immunol. 131:1531-1538.
41. Bukowski JF, Warner JF, Dennert G, Welsh RM. 1985. Adoptive transfer studies demonstrating the antiviral effect of natural killer cells in vivo. J. Exp. Med. 161:40-52.
42. Bukowski JF, Yang H, Welsh RM. 1988. Antiviral effect of lymphokineactivated killer cells: characterization of effector cells mediating prophylaxis. J. Virol. 62:3642-3648.
43. van den Broek MF, Müller U, Huang S, Zinkernagel RM, Aguet M. 1995. Immune defence in mice lacking type I and/or type II interferon receptors. Immunol. Rev. 148:5-18.
44. Pien GC, Biron CA. 2000. Compartmental differences in NK cell responsiveness to IL-12 during lymphocytic choriomeningitis virus infection. J. Immunol. 164:994-1001.
45. Biron CA, Sen GC. 2007. Innate immune responses to viral infections, p 249-278. In Knipe DM, Howley PM (ed), Fields virology, 5th ed. Wolters Kluwer/Lippincott, Williams & Wilkins, Philadelphia, PA.
46. Miyagi T, Lee SH, Biron CA. 2010. Intracellular staining for analysis of the expression and phosphorylation of signal transducers and activators of transcription (STATs) in NK cells. Methods Mol. Biol. 612:159-175.