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Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 19, 2011, Pages 5726-5729

Synthesis and biological evaluation of α,β-unsaturated lactones as potent immunosuppressive agents

(4) Lee, Sun Mi a Lee, Won Gil a Kim, Young Chul a Ko, Hyojin a

a Gwangju Institute of Science and Technology (GIST) (South Korea)

Author keywords

, Unsaturated lactones; Immunosuppressive effect; Interleukin 2 (IL 2) inhibition

Indexed keywords

IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 2; LACTONE DERIVATIVE;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL;

CYTOTOXICITY TESTS, IMMUNOLOGIC; DRUG EVALUATION, PRECLINICAL; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INFLAMMATION; INHIBITORY CONCENTRATION 50; INTERLEUKIN-2; JURKAT CELLS; LACTONES; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; T-LYMPHOCYTES;

EID: 80052571022 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2011.08.020 Document Type: Article

Times cited : (18)

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