Erratum: Reversible Michael addition of thiols as a new tool for dynamic combinatorial chemistry (Chemical Communications (2005) (886-888) DOI: 10.1039/b414300k);Reversible Michael addition of thiols as a new tool for dynamic combinatorial chemistry

Chemical Communications

Volumn , Issue 7, 2005, Pages 886-888

  Shi, Baolu ^a   Greaney, Michael F ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

THIOL DERIVATIVE;

ARTICLE; CHEMICAL REACTION KINETICS; COMBINATORIAL CHEMISTRY; MICHAEL ADDITION; MOLECULAR DYNAMICS; PH; QUALITATIVE ANALYSIS; ROOM TEMPERATURE; STOICHIOMETRY; THERMODYNAMICS;

EID: 14644411748     PISSN: 13597345     EISSN: None     Source Type: Journal    
DOI: 10.1039/b414300k     Document Type: Erratum

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26. The amides 5a-9a were synthesised through EDCI coupling of commercially available EA to the appropriate amine.
27. Each adduct is a mixture of diastereoisomers due to the newly formed stereocentre α to the ketone in the Michael acceptors. Adduct 5a was synthesised separately and shown to be a 1 : 1 diastereomeric mixture (see ESI†). Resolution of each diastereoisomer could not be achieved on the LC-column.