Therapeutic effects of novel sphingosine-1-phosphate receptor agonist W-061 in murine DSS colitis

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Sanada, Yasuaki ^a   Mizushima, Tsunekazu ^a   Kai, Yasuyuki ^a   Nishimura, Junichi ^a   Hagiya, Hiroshi ^b   Kurata, Haruto ^b   Mizuno, Hirotaka ^b   Uejima, Etsuko ^a   Ito, Toshinori ^a  

^a OSAKA UNIVERSITY   (Japan)

^b ONO PHARMACEUTICAL CO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; CYTOKINE; DEXTRAN SULFATE; FINGOLIMOD; INTERLEUKIN 17; SPHINGOSINE 1 PHOSPHATE RECEPTOR; UNCLASSIFIED DRUG; W 061;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; COLITIS; COLON; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG ACTIVITY; DRUG EFFECT; ENTERITIS; HISTOPATHOLOGY; LAMINA PROPRIA; LYMPHOCYTE; LYMPHOCYTE COUNT; LYMPHOCYTE MIGRATION; LYMPHOCYTE SUBPOPULATION; MALE; MESENTERY LYMPH NODE; MOUSE; NONHUMAN; PATHOGENESIS; PEYER PATCH; REGULATORY T LYMPHOCYTE; SPLEEN; TH1 CELL; TH17 CELL; ANIMAL; BAGG ALBINO MOUSE; BODY WEIGHT; CELL MOTION; CHEMICALLY INDUCED DISORDER; CHO CELL; CRICETULUS; CYTOLOGY; DRUG ADMINISTRATION; DRUG POTENTIATION; ENZYME SPECIFICITY; HAMSTER; HUMAN; IMMUNOLOGY; MUCOSA; ORGAN SIZE; PATHOLOGY;

MURINAE;

ANIMALS; BODY WEIGHT; CELL MOVEMENT; CHO CELLS; COLITIS; COLON; CRICETINAE; CRICETULUS; DEXTRAN SULFATE; DRUG ADMINISTRATION SCHEDULE; HUMANS; MALE; MICE; MICE, INBRED BALB C; MUCOUS MEMBRANE; ORGAN SIZE; RECEPTORS, LYSOSPHINGOLIPID; SUBSTRATE SPECIFICITY; T-LYMPHOCYTES, REGULATORY; TH17 CELLS;

EID: 80052542781     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023933     Document Type: Article

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