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Volumn 39, Issue 9, 2011, Pages 1989-1996

Pain perception in knees with circumscribed cartilage lesions is associated with intra-articular IGF-1 expression

Author keywords

aggrecan; bFGF; BMP 2; BMP 7; cartilage repair; clinical trial; cytokine; IGF 1; IL 1 ; intra articular; pain; prospective; smoking

Indexed keywords

CYTOKINE; SOMATOMEDIN C;

EID: 80052532406     PISSN: 03635465     EISSN: 15523365     Source Type: Journal    
DOI: 10.1177/0363546511406851     Document Type: Article
Times cited : (20)

References (48)
  • 1
    • 77954344675 scopus 로고    scopus 로고
    • The potential of human allogeneic juvenile chondrocytes for restoration of articular cartilage
    • Adkisson HD, Martin JA, Amendola RL, et al. The potential of human allogeneic juvenile chondrocytes for restoration of articular cartilage. Am J Sports Med. 2010 ; 38 (7). 1324-1333
    • (2010) Am J Sports Med , vol.38 , Issue.7 , pp. 1324-1333
    • Adkisson, H.D.1    Martin, J.A.2    Amendola, R.L.3
  • 2
    • 0032981906 scopus 로고    scopus 로고
    • Neurotrophic factors and diabetic peripheral neuropathy
    • Apfel SC. Neurotrophic factors and diabetic peripheral neuropathy. Eur Neurol. 1999 ; 41 (Suppl 1). 27-34 (Pubitemid 29099612)
    • (1999) European Neurology , vol.41 , Issue.SUPPL. 1 , pp. 27-34
    • Apfel, S.C.1
  • 3
    • 78651446635 scopus 로고    scopus 로고
    • Dual energy x-ray absorptiometry analysis contributes to the prediction of hip osteoarthritis progression
    • Betancourt MC, Linden JC, Rivadeneira F, et al. Dual energy x-ray absorptiometry analysis contributes to the prediction of hip osteoarthritis progression. Arthritis Res Ther. 2009 ; 11 (6). R162
    • (2009) Arthritis Res Ther , vol.11 , Issue.6 , pp. 162
    • Betancourt, M.C.1    Linden, J.C.2    Rivadeneira, F.3
  • 5
    • 0028031550 scopus 로고
    • Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation
    • DOI 10.1056/NEJM199410063311401
    • Brittberg M, Lindahl A, Nilsson A, Ohlsson C, Isaksson O, Peterson L. Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N Engl J Med. 1994 ; 331 (14). 889-895 (Pubitemid 24299869)
    • (1994) New England Journal of Medicine , vol.331 , Issue.14 , pp. 889-895
    • Brittberg, M.1    Lindahl, A.2    Nilsson, A.3    Ohlsson, C.4    Isaksson, O.5    Peterson, L.6
  • 7
    • 36349005015 scopus 로고    scopus 로고
    • Osteogenic protein 1 in synovial fluid from patients with rheumatoid arthritis or osteoarthritis: Relationship with disease and levels of hyaluronan and antigenic keratan sulfate
    • Chubinskaya S, Frank BS, Michaëlska M, et al. Osteogenic protein 1 in synovial fluid from patients with rheumatoid arthritis or osteoarthritis: relationship with disease and levels of hyaluronan and antigenic keratan sulfate. Arthritis Res Ther. 2006 ; 8 (3). R73
    • (2006) Arthritis Res Ther , vol.8 , Issue.3 , pp. 73
    • Chubinskaya, S.1    Frank, B.S.2    Michaëlska, M.3
  • 8
    • 22244487984 scopus 로고    scopus 로고
    • Association of cartilage defects with loss of knee cartilage in healthy, middle-age adults: A prospective study
    • DOI 10.1002/art.21148
    • Cicuttini F, Ding C, Wluka A, Davis S, Ebeling PR, Jones G. Association of cartilage defects with loss of knee cartilage in healthy, middle-age adults: a prospective study. Arthritis Rheum. 2005 ; 52 (7). 2033-2039 (Pubitemid 40994326)
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.7 , pp. 2033-2039
    • Cicuttini, F.1    Ding, C.2    Wluka, A.3    Davis, S.4    Ebeling, P.R.5    Jones, G.6
  • 9
    • 70350759762 scopus 로고    scopus 로고
    • Smoking is associated with increased cartilage loss and persistence of bone marrow lesions over 2 years in community-based individuals
    • Davies-Tuck ML, Wluka AE, Forbes A, et al. Smoking is associated with increased cartilage loss and persistence of bone marrow lesions over 2 years in community-based individuals. Rheumatology (Oxford). 2009 ; 48 (10). 1227-1231
    • (2009) Rheumatology (Oxford) , vol.48 , Issue.10 , pp. 1227-1231
    • Davies-Tuck, M.L.1    Wluka, A.E.2    Forbes, A.3
  • 10
    • 35248867194 scopus 로고    scopus 로고
    • Arthritis and pain: Future targets to control osteoarthritis pain
    • Dray A, Read SJ. Arthritis and pain: future targets to control osteoarthritis pain. Arthritis Res Ther. 2007 ; 9 (3). 212
    • (2007) Arthritis Res Ther , vol.9 , Issue.3 , pp. 212
    • Dray, A.1    Read, S.J.2
  • 11
    • 0034176507 scopus 로고    scopus 로고
    • Long-term results of anterior cruciate ligament reconstruction using ilio-tibial tract and semitendinosis tendon
    • DOI 10.1016/S0968-0160(00)00035-1, PII S0968016000000351
    • Edwards DJ, Brown JN, Roberts SN, Paterson RS. Long-term results of anterior cruciate ligament reconstruction using ilio-tibial tract and semitendinosis tendon. Knee. 2000 ; 7 (2). 87-93 (Pubitemid 30219443)
    • (2000) Knee , vol.7 , Issue.2 , pp. 87-93
    • Edwards, D.J.1    Brown, J.N.2    Roberts, S.N.J.3    Paterson, R.S.4
  • 12
    • 34547478297 scopus 로고    scopus 로고
    • Serum cartilage oligomeric matrix protein (COMP) levels in knee osteoarthritis in a Brazilian population: Clinical and radiological correlation
    • DOI 10.1080/03009740601154186, PII 780896555, Extending the Bounds of Power Transition Theory
    • Fernandes FA, Pucinelli ML, da Silva NP, Feldman D. Serum cartilage oligomeric matrix protein (COMP) levels in knee osteoarthritis in a Brazilian population: clinical and radiological correlation. Scand J Rheumatol. 2007 ; 36 (3). 211-215 (Pubitemid 47174552)
    • (2007) Scandinavian Journal of Rheumatology , vol.36 , Issue.3 , pp. 211-215
    • Fernandes, F.A.1    Pucinelli, M.L.C.2    Da Silva, N.P.3    Feldman, D.4
  • 14
    • 33846699802 scopus 로고    scopus 로고
    • Morphology, mechanisms and pathology of musculoskeletal ageing
    • DOI 10.1002/path.2097
    • Freemont AJ, Hoyland JA. Morphology, mechanisms and pathology of musculoskeletal ageing. J Pathol. 2007 ; 211 (2). 252-259 (Pubitemid 46195523)
    • (2007) Journal of Pathology , vol.211 , Issue.2 , pp. 252-259
    • Freemont, A.J.1    Hoyland, J.A.2
  • 15
    • 39749170727 scopus 로고    scopus 로고
    • Growth and differentiation factors for cartilage healing and repair
    • Gaissmaier C, Koh JL, Weise K. Growth and differentiation factors for cartilage healing and repair. Injury. 2008 ; 39 (Suppl 1). S88 - S96
    • (2008) Injury , vol.39 , Issue.SUPPL. 1
    • Gaissmaier, C.1    Koh, J.L.2    Weise, K.3
  • 16
    • 77957697385 scopus 로고    scopus 로고
    • The synovial fluid adiponectin-leptin ratio predicts pain with knee osteoarthritis
    • Gandhi R, Takahashi M, Smith H, Rizek R, Mahomed NN. The synovial fluid adiponectin-leptin ratio predicts pain with knee osteoarthritis. Clin Rheumatol. 2010 ; 29 (11). 1223-1228
    • (2010) Clin Rheumatol , vol.29 , Issue.11 , pp. 1223-1228
    • Gandhi, R.1    Takahashi, M.2    Smith, H.3    Rizek, R.4    Mahomed, N.N.5
  • 17
    • 0023931347 scopus 로고
    • Measurement of synovial fluid volume using albumin dilution upon intraarticular saline injection
    • Geborek P, Saxne T, Heinegard D, Wollheim FA. Measurement of synovial fluid volume using albumin dilution upon intraarticular saline injection. J Rheumatol. 1988 ; 15 (1). 91-94 (Pubitemid 18051539)
    • (1988) Journal of Rheumatology , vol.15 , Issue.1 , pp. 91-94
    • Geborek, P.1    Saxne, T.2    Heinegard, D.3    Wollheim, F.A.4
  • 18
    • 33749829097 scopus 로고    scopus 로고
    • Treatment of full-thickness chondral defects in the knee with autologous chondrocyte implantation
    • DOI 10.2519/jospt.2006.2409
    • Gillogly SD, Myers TH, Reinold MM. Treatment of full-thickness chondral defects in the knee with autologous chondrocyte implantation. J Orthop Sports Phys Ther. 2006 ; 36 (10). 751-764 (Pubitemid 44563795)
    • (2006) Journal of Orthopaedic and Sports Physical Therapy , vol.36 , Issue.10 , pp. 751-764
    • Gillogly, S.D.1    Myers, T.H.2    Reinold, M.M.3
  • 19
    • 41149098279 scopus 로고    scopus 로고
    • Changes in biochemical markers and prediction of effectiveness of intra-articular hyaluronan in patients with knee osteoarthritis
    • DOI 10.1016/j.joca.2007.09.014, PII S1063458407003135
    • Hasegawa M, Nakoshi Y, Tsujii M, et al. Changes in biochemical markers and prediction of effectiveness of intra-articular hyaluronan in patients with knee osteoarthritis. Osteoarthritis Cartilage. 2008 ; 16 (4). 526-529 (Pubitemid 351426275)
    • (2008) Osteoarthritis and Cartilage , vol.16 , Issue.4 , pp. 526-529
    • Hasegawa, M.1    Nakoshi, Y.2    Tsujii, M.3    Sudo, A.4    Masuda, H.5    Yoshida, T.6    Uchida, A.7
  • 20
    • 68349123665 scopus 로고    scopus 로고
    • Relationship of plasma and synovial fluid BMP-7 with disease severity in knee osteoarthritis patients: A pilot study
    • Honsawek S, Chayanupatkul M, Tanavalee A, et al. Relationship of plasma and synovial fluid BMP-7 with disease severity in knee osteoarthritis patients: a pilot study. Int Orthop. 2009 ; 33 (4). 1171-1175
    • (2009) Int Orthop , vol.33 , Issue.4 , pp. 1171-1175
    • Honsawek, S.1    Chayanupatkul, M.2    Tanavalee, A.3
  • 21
    • 77951081160 scopus 로고    scopus 로고
    • Obesity and inflammation-targets for OA therapy
    • Iannone F, Lapadula G. Obesity and inflammation-targets for OA therapy. Curr Drug Targets. 2010 ; 11 (5). 586-598
    • (2010) Curr Drug Targets , vol.11 , Issue.5 , pp. 586-598
    • Iannone, F.1    Lapadula, G.2
  • 22
    • 0028873368 scopus 로고
    • Implication of insulin-like growth factors in the pathogenesis of diabetic neuropathy
    • Ishii DN. Implication of insulin-like growth factors in the pathogenesis of diabetic neuropathy. Brain Res Brain Res Rev. 1995 ; 20 (1). 47-67
    • (1995) Brain Res Brain Res Rev , vol.20 , Issue.1 , pp. 47-67
    • Ishii, D.N.1
  • 23
    • 0028819340 scopus 로고
    • Insulin-like growth factors protect against diabetic neuropathy: Effects on sensory nerve regeneration in rats
    • Ishii DN, Lupien SB. Insulin-like growth factors protect against diabetic neuropathy: effects on sensory nerve regeneration in rats. J Neurosci Res. 1995 ; 40 (1). 138-144
    • (1995) J Neurosci Res , vol.40 , Issue.1 , pp. 138-144
    • Ishii, D.N.1    Lupien, S.B.2
  • 25
    • 0037022711 scopus 로고    scopus 로고
    • Retention and activity of BMP-2 in hyaluronic acid-based scaffolds in vitro
    • DOI 10.1002/jbm.10011
    • Kim HD, Valentini RF. Retention and activity of BMP-2 in hyaluronic acid-based scaffolds in vitro. J Biomed Mater Res. 2002 ; 59 (3). 573-584 (Pubitemid 34037502)
    • (2002) Journal of Biomedical Materials Research , vol.59 , Issue.3 , pp. 573-584
    • Kim, H.D.1    Valentini, R.F.2
  • 27
    • 50849119107 scopus 로고    scopus 로고
    • A role for the aryl hydrocarbon receptor and the dioxin TCDD in rheumatoid arthritis
    • Kobayashi S, Okamoto H, Iwamoto T, et al. A role for the aryl hydrocarbon receptor and the dioxin TCDD in rheumatoid arthritis. Rheumatology (Oxford). 2008 ; 47 (9). 1317-1322
    • (2008) Rheumatology (Oxford) , vol.47 , Issue.9 , pp. 1317-1322
    • Kobayashi, S.1    Okamoto, H.2    Iwamoto, T.3
  • 29
    • 0027935871 scopus 로고
    • Serum insulin-like growth factor I in a random population sample of men and women: Relation to age, sex, smoking habits, coffee consumption and physical activity, blood pressure and concentrations of plasma lipids, fibrinogen, parathyroid hormone and osteocalcin
    • Landin-Wilhelmsen K, Wilhelmsen L, Lappas G, et al. Serum insulin-like growth factor I in a random population sample of men and women: relation to age, sex, smoking habits, coffee consumption and physical activity, blood pressure and concentrations of plasma lipids, fibrinogen, parathyroid hormone and osteocalcin. Clin Endocrinol (Oxf). 1994 ; 41 (3). 351-357 (Pubitemid 24278330)
    • (1994) Clinical Endocrinology , vol.41 , Issue.3 , pp. 351-357
    • Landin-Wilhelmsen, K.1    Wilhelmsen, L.2    Lappas, G.3    Rosen, T.4    Lindstedt, G.5    Lundberg, P.6    Bengtsson, B.7
  • 30
    • 0041571728 scopus 로고    scopus 로고
    • The combination of insulin-like growth factor 1 and osteogenic protein 1 promotes increased survival of and matrix synthesis by normal and osteoarthritic human articular chondrocytes
    • DOI 10.1002/art.11209
    • Loeser RF, Pacione CA, Chubinskaya S. The combination of insulin-like growth factor 1 and osteogenic protein 1 promotes increased survival of and matrix synthesis by normal and osteoarthritic human articular chondrocytes. Arthritis Rheum. 2003 ; 48 (8). 2188-2196 (Pubitemid 36959199)
    • (2003) Arthritis and Rheumatism , vol.48 , Issue.8 , pp. 2188-2196
    • Loeser, R.F.1    Pacione, C.A.2    Chubinskaya, S.3
  • 31
    • 0024352667 scopus 로고
    • Increased levels of proteoglycan fragments in knee joint fluid after injury
    • DOI 10.1002/anr.1780321113
    • Lohmander LS, Dahlberg L, Ryd L, Heinegard D. Increased levels of proteoglycan fragments in knee joint fluid after injury. Arthritis Rheum. 1989 ; 32 (11). 1434-1442 (Pubitemid 20003911)
    • (1989) Arthritis and Rheumatism , vol.32 , Issue.11 , pp. 1434-1442
    • Lohmander, L.S.1    Dahlberg, L.2    Ryd, L.3    Heinegard, D.4
  • 32
    • 0027400612 scopus 로고
    • Levels of insulin related growth factor 1 in osteoarthritis of the knee
    • McAlindon TE, Teale JD, Dieppe PA. Levels of insulin related growth factor 1 in osteoarthritis of the knee. Ann Rheum Dis. 1993 ; 52 (3). 229-231 (Pubitemid 23094314)
    • (1993) Annals of the Rheumatic Diseases , vol.52 , Issue.3 , pp. 229-231
    • McAlindon, T.E.1    Teale, J.D.2    Dieppe, P.A.3
  • 33
    • 0033304963 scopus 로고    scopus 로고
    • Editorial: Insulin-like growth factor I - A prototypic peripheral-paracrine hormone?
    • Melmed S. Insulin-like growth factor I-a prototypic peripheral-paracrine hormone?. Endocrinology. 1999 ; 140 (9). 3879-3880 (Pubitemid 30647080)
    • (1999) Endocrinology , vol.140 , Issue.9 , pp. 3879-3880
    • Melmed, S.1
  • 34
    • 73249136354 scopus 로고    scopus 로고
    • Denuded subchondral bone and knee pain in persons with knee osteoarthritis
    • Moisio K, Eckstein F, Chmiel JS, et al. Denuded subchondral bone and knee pain in persons with knee osteoarthritis. Arthritis Rheum. 2009 ; 60 (12). 3703-3710
    • (2009) Arthritis Rheum , vol.60 , Issue.12 , pp. 3703-3710
    • Moisio, K.1    Eckstein, F.2    Chmiel, J.S.3
  • 35
    • 79952113422 scopus 로고    scopus 로고
    • Presence of subchondral bone marrow edema at the time of treatment represents a negative prognostic factor for early outcome after autologous chondrocyte implantation
    • Niemeyer P, Salzmann G, Steinwachs M, et al. Presence of subchondral bone marrow edema at the time of treatment represents a negative prognostic factor for early outcome after autologous chondrocyte implantation. Arch Orthop Trauma Surg. 2010 ; 130 (8). 977-983
    • (2010) Arch Orthop Trauma Surg , vol.130 , Issue.8 , pp. 977-983
    • Niemeyer, P.1    Salzmann, G.2    Steinwachs, M.3
  • 36
    • 70450202838 scopus 로고    scopus 로고
    • Detection of pain-related molecules in the subchondral bone of osteoarthritic knees
    • Ogino S, Sasho T, Nakagawa K, et al. Detection of pain-related molecules in the subchondral bone of osteoarthritic knees. Clin Rheumatol. 2009 ; 28 (12). 1395-1402
    • (2009) Clin Rheumatol , vol.28 , Issue.12 , pp. 1395-1402
    • Ogino, S.1    Sasho, T.2    Nakagawa, K.3
  • 37
    • 77953289025 scopus 로고    scopus 로고
    • Cartilage degeneration is associated with augmented chemically-induced joint pain in rats: A pilot study
    • Okamoto M, Atsuta Y. Cartilage degeneration is associated with augmented chemically-induced joint pain in rats: a pilot study. Clin Orthop Relat Res. 2010 ; 468 (5). 1423-1427
    • (2010) Clin Orthop Relat Res , vol.468 , Issue.5 , pp. 1423-1427
    • Okamoto, M.1    Atsuta, Y.2
  • 38
    • 64049107675 scopus 로고    scopus 로고
    • Independent alterations in the central and peripheral somatosensory pathways in rat diabetic neuropathy
    • Piriz J, Torres-Aleman I, Nunez A. Independent alterations in the central and peripheral somatosensory pathways in rat diabetic neuropathy. Neuroscience. 2009 ; 160 (2). 402-411
    • (2009) Neuroscience , vol.160 , Issue.2 , pp. 402-411
    • Piriz, J.1    Torres-Aleman, I.2    Nunez, A.3
  • 39
    • 38349128259 scopus 로고    scopus 로고
    • Characterized chondrocyte implantation results in better structural repair when treating symptomatic cartilage defects of the knee in a randomized controlled trial versus microfracture
    • Saris DB, Vanlauwe J, Victor J, et al. Characterized chondrocyte implantation results in better structural repair when treating symptomatic cartilage defects of the knee in a randomized controlled trial versus microfracture. Am J Sports Med. 2008 ; 36 (2). 235-246
    • (2008) Am J Sports Med , vol.36 , Issue.2 , pp. 235-246
    • Saris, D.B.1    Vanlauwe, J.2    Victor, J.3
  • 40
    • 71149104044 scopus 로고    scopus 로고
    • In vivo quantification of intraarticular cytokines in knees during natural and surgically induced cartilage repair
    • Schmal H, Mehlhorn A, Stoffel F, Kostler W, Sudkamp NP, Niemeyer P. In vivo quantification of intraarticular cytokines in knees during natural and surgically induced cartilage repair. Cytotherapy. 2009 ; 11 (8). 1065-1075
    • (2009) Cytotherapy , vol.11 , Issue.8 , pp. 1065-1075
    • Schmal, H.1    Mehlhorn, A.2    Stoffel, F.3    Kostler, W.4    Sudkamp, N.P.5    Niemeyer, P.6
  • 41
    • 77955002078 scopus 로고    scopus 로고
    • Association between expression of the bone morphogenetic proteins 2 and 7 in the repair of circumscribed cartilage lesions with clinical outcome
    • Schmal H, Niemeyer P, Zwingmann J, Stoffel F, Suedkamp NP, Mehlhorn AT. Association between expression of the bone morphogenetic proteins 2 and 7 in the repair of circumscribed cartilage lesions with clinical outcome. BMC Musculoskelet Disord. 2010 ; 11 (1). 170
    • (2010) BMC Musculoskelet Disord , vol.11 , Issue.1 , pp. 170
    • Schmal, H.1    Niemeyer, P.2    Zwingmann, J.3    Stoffel, F.4    Suedkamp, N.P.5    Mehlhorn, A.T.6
  • 42
    • 77955176250 scopus 로고    scopus 로고
    • The evolving role of obesity in knee osteoarthritis
    • Sowers MR, Karvonen-Gutierrez CA. The evolving role of obesity in knee osteoarthritis. Curr Opin Rheumatol. 2010 ; 22 (5). 533-537
    • (2010) Curr Opin Rheumatol , vol.22 , Issue.5 , pp. 533-537
    • Sowers, M.R.1    Karvonen-Gutierrez, C.A.2
  • 43
    • 33750480513 scopus 로고    scopus 로고
    • Factors Affecting the Outcome of Arthroscopy in Medial-Compartment Osteoarthritis of the Knee
    • DOI 10.1016/j.arthro.2006.07.003, PII S0749806306008784
    • Spahn G, Muckley T, Kahl E, Hofmann GO. Factors affecting the outcome of arthroscopy in medial-compartment osteoarthritis of the knee. Arthroscopy. 2006 ; 22 (11). 1233-1240 (Pubitemid 44648673)
    • (2006) Arthroscopy - Journal of Arthroscopic and Related Surgery , vol.22 , Issue.11 , pp. 1233-1240
    • Spahn, G.1    Muckley, T.2    Kahl, E.3    Hofmann, G.O.4
  • 44
    • 77952301751 scopus 로고    scopus 로고
    • The association between leptin, interleukin-6, and hip radiographic osteoarthritis in older people: A cross-sectional study
    • Stannus OP, Jones G, Quinn SJ, Cicuttini FM, Dore D, Ding C. The association between leptin, interleukin-6, and hip radiographic osteoarthritis in older people: a cross-sectional study. Arthritis Res Ther. 2010 ; 12 (3). R95
    • (2010) Arthritis Res Ther , vol.12 , Issue.3 , pp. 95
    • Stannus, O.P.1    Jones, G.2    Quinn, S.J.3    Cicuttini, F.M.4    Dore, D.5    Ding, C.6
  • 45
    • 58549113759 scopus 로고    scopus 로고
    • New technique for cell-seeded collagen-matrix-supported autologous chondrocyte transplantation
    • Steinwachs M. New technique for cell-seeded collagen-matrix-supported autologous chondrocyte transplantation. Arthroscopy. 2009 ; 25 (2). 208-211
    • (2009) Arthroscopy , vol.25 , Issue.2 , pp. 208-211
    • Steinwachs, M.1
  • 47
    • 73649118465 scopus 로고    scopus 로고
    • Cytokine receptor-like factor 1 is highly expressed in damaged human knee osteoarthritic cartilage and involved in osteoarthritis downstream of TGF-beta
    • Tsuritani K, Takeda J, Sakagami J, et al. Cytokine receptor-like factor 1 is highly expressed in damaged human knee osteoarthritic cartilage and involved in osteoarthritis downstream of TGF-beta. Calcif Tissue Int. 2010 ; 86 (1). 47-57
    • (2010) Calcif Tissue Int , vol.86 , Issue.1 , pp. 47-57
    • Tsuritani, K.1    Takeda, J.2    Sakagami, J.3
  • 48
    • 78649742263 scopus 로고    scopus 로고
    • Relationship between bone marrow lesions, cartilage loss and pain in knee osteoarthritis: Results from a randomised controlled clinical trial using MRI
    • Wildi LM, Raynauld JP, Martel-Pelletier J, Abram F, Dorais M, Pelletier JP. Relationship between bone marrow lesions, cartilage loss and pain in knee osteoarthritis: results from a randomised controlled clinical trial using MRI. Ann Rheum Dis. 2010 ; 69 (12). 2118-2124
    • (2010) Ann Rheum Dis , vol.69 , Issue.12 , pp. 2118-2124
    • Wildi, L.M.1    Raynauld, J.P.2    Martel-Pelletier, J.3    Abram, F.4    Dorais, M.5    Pelletier, J.P.6


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