A randomized trial comparing autologous chondrocyte implantation with microfracture: Findings at five years

Journal of Bone and Joint Surgery

Volumn 89, Issue 10, 2007, Pages 2105-2112

  Knutsen, Gunnar ^a   Drogset, Jon Olav ^b   Engebretsen, Lars ^c   Grøntvedt, Torbjørn ^b   Isaksen, Vidar ^a   Ludvigsen, Tom C ^c   Roberts, Sally ^d   Solheim, Eirik ^e   Strand, Torbjørn ^e   Johansen, Oddmund ^a  

^a UNIVERSITY OF TROMSØ   (Norway)

^b TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

^c UNIVERSITY OF OSLO   (Norway)

^d ROBERT JONES AND AGNES HUNT ORTHOPAEDIC HOSPITAL   (United Kingdom)

^e HAUKELAND UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ANTERIOR CRUCIATE LIGAMENT RUPTURE; ARTICLE; AUTOTRANSPLANTATION; CARTILAGE CELL; CHONDROPATHY; CHRONIC DISEASE; DISEASE COURSE; FEMUR; FEMUR CONDYLE; FOLLOW UP; HISTOLOGY; HUMAN; HUMAN TISSUE; HYALINE CARTILAGE; KELLGREN AND LAWRENCE GRADING SYSTEM; KNEE ARTHROSCOPY; KNEE INJURY; KNEE MENISCUS RUPTURE; KNEE OSTEOARTHRITIS; KNEE RADIOGRAPHY; KNEE SURGERY; LYSHOLM SCORE; MAJOR CLINICAL STUDY; MICROFRACTURE; OSTEOCHONDRITIS DISSECANS; PAIN ASSESSMENT; PRIORITY JOURNAL; REOPERATION; SCORING SYSTEM; SHORT FORM 36; TEGNER SCORE; TIBIA; TIBIA OSTEOTOMY; TREATMENT FAILURE; TREATMENT OUTCOME; VISUAL ANALOG SCALE;

EID: 35349025844     PISSN: 00219355     EISSN: None     Source Type: Journal    
DOI: 10.2106/JBJS.G.00003     Document Type: Article

References (29)

1. Aroen A, Loken S, Heir S, Alvik E, Ekeland A, Granlund OG, Engebretsen L. Articular cartilage lesions in 993 consecutive knee arthroscopies. Am J Sports Med. 2004;32:211-5.
2. Curl WW, Krome J, Gordon ES, Rushing J, Smith BP, Poehling GG. Cartilage injuries: a review of 31,516 knee arthroscopies. Arthroscopy. 1997;13:456-60.
3. Hjelle K, Solheim E, Strand T, Muri R, Brittberg M. Articular cartilage defects in 1,000 knee arthroscopies. Arthroscopy. 2002;18:730-4.
4. Brittberg M, Lindahl A, Nilsson A, Ohlsson C, Isaksson O, Peterson L. Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N Engl J Med. 1994;331:889-95.
5. Steadman JR, Briggs KK, Rodrigo JJ, Kocher MS, Gill TJ, Rodkey WG. Outcomes of microfracture for traumatic chondral defects of the knee: average 11-year follow-up. Arthroscopy. 2003;19:477-84.
6. Wasiak J, Clar C, Villanueva E. Autologous cartilage implantation for full thickness articular cartilage defects of the knee. Cochrane Database Syst Rev. 2006;3:CD003323.
7. Jakobsen RB, Engebretsen L, Slauterbeck JR. An analysis of the quality of cartilage repair studies. J Bone Joint Surg Am. 2005;87:2232-9.
8. Knutsen G, Engebretsen L, Ludvigsen TC, Drogset JO, Grontvedt T, Solheim E, Strand T, Roberts S, Isaksen V, Johansen O. Autologous chondrocyte implantation compared with microfracture in the knee. A randomized trial. J Bone Joint Surg Am. 2004;86:455-64.
9. International Cartilage Repair Society. www.cartilage.org.
10. Lysholm J, Gillquist J. Evaluation of knee ligament surgery results with special emphasis on use of a scoring scale. Am J Sports Med. 1982;10:150-4.
11. Tegner Y, Lysholm J. Rating systems in the evaluation of knee ligament injuries. Clin Orthop Relat Res. 1985;198:43-9.
12. Ware JE Jr, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992;30:473-83.
13. Peterson L, Brittberg M, Kiviranta I, Akerlund EL, Lindahl A. Autologous chondrocyte transplantation. Biomechanics and long-term durability. Am J Sports Med. 2002;30:2-12.
14. Steadman JR, Rodkey WG, Briggs KK. Microfracture to treat full-thickness chondral defects: surgical technique, rehabilitation, and outcomes. J Knee Surg. 2002;15:170-6.
15. Kellgren JH, Lawrence JS. Radiological assessment of osteo-arthrosis. Ann Rheum Dis. 1957;16:494-502.
16. Kreuz PC, Steinwachs MR, Erggelet C, Krause SJ, Konrad G, Uhl M, Sudkamp N. Results after microfracture of full-thickness chondral defects in different compartments in the knee. Osteoarthritis Cartilage. 2006;14:1119-25.
17. Linden B. Osteochondritis dissecans of the femoral condyles: a long-term follow-up study. J Bone Joint Surg Am. 1977;59:769-76.
18. Shelbourne KD, Jari S, Gray T. Outcome of untreated traumatic articular cartilage defects of the knee: a natural history study. J Bone Joint Surg Am. 2003;85 Suppl 2:8-16.
19. Drogset JO, Grontvedt T. Anterior cruciate ligament reconstruction with and without a ligament augmentation device: results at 8-Year follow-up. Am J Sports Med. 2002;30:851-6.
20. Von Korff M, Miglioretti DL. A prognostic approach to defining chronic pain. Pain. 2005;117:304-13.
21. Browne JE, Anderson AF, Arciero R, Mandelbaum B, Moseley JB Jr, Micheli LJ, Fu F, Erggelet C. Clinical outcome of autologous chondrocyte implantation at 5 years in US subjects. Clin Orthop Relat Res. 2005;436:237-45.
22. Horas U, Pelinkovic D, Herr G, Aigner T, Schnettler R. Autologous chondrocyte implantation and osteochondral cylinder transplantation in cartilage repair of the knee joint. A prospective, comparative trial. J Bone Joint Surg Am. 2003;85:185-92.
23. Bentley G, Biant LC, Carrington RW, Akmal M, Goldberg A, Williams AM, Skinner JA, Pringle J. A prospective, randomised comparison of autologous chondrocyte implantation versus mosaicplasty for osteochondral defects in the knee. J Bone Joint Surg Br. 2003;85:223-30.
24. Bachmann G, Basad E, Lommel D, Steinmeyer J. [MRI in the follow-up of matrix-supported autologous chondrocyte transplantation (MACI) and microfracture]. Radiologe. 2004;44:773-82. German.
25. Haugegaard M, Jørgensen U, Nicolaisen T, Konradsen L, Oster K. Treatment of isolated cartilage defects in the knee in patients with chronic knee pain. A double blinded prospective randomised trial with periosteal cover +/- autologous chondrocyte implantation (ACI). International Cartilage Repair Society 6th Symposium. 2006. San Diego, CA.
26. Lohmander LS, Ostenberg A, Englund M, Roos H. High prevalence of knee osteoarthritis, pain, and functional limitations in female soccer players twelve years after anterior cruciate ligament injury. Arthritis Rheum. 2004;50:3145-52.
27. Englund M. Meniscal tear - a feature of osteoarthritis. Acta Orthop Scand Suppl. 2004;75:1-45, backcover.
28. Appel H. Late results after meniscectomy in the knee joint. A clinical and roentgenologic follow-up investigation. Acta Orthop Scand Suppl. 1970;133:1-111.
29. Davis MA. Epidemiology of osteoarthritis. Clin Geriatr Med. 1988;4:241-55.