-
1
-
-
0028016267
-
Age related histomorphometric changes in bone in normal British men and women
-
Rehman MTA, Hoyland JA, Denton J, Freemont AJ. Age related histomorphometric changes in bone in normal British men and women. J Clin Pathol 1994;47(6):529-534.
-
(1994)
J Clin Pathol
, vol.47
, Issue.6
, pp. 529-534
-
-
Rehman, M.T.A.1
Hoyland, J.A.2
Denton, J.3
Freemont, A.J.4
-
2
-
-
27944480412
-
Pathophysiology of age-related bone loss and osteoporosis
-
Khosla S, Riggs BL. Pathophysiology of age-related bone loss and osteoporosis. Endocrinol Metab Clin North Am 2005;34(4):1015-1030.
-
(2005)
Endocrinol Metab Clin North Am
, vol.34
, Issue.4
, pp. 1015-1030
-
-
Khosla, S.1
Riggs, B.L.2
-
3
-
-
0030451290
-
The pathophysiology of cartilage and synovium
-
Freemont AJ. The pathophysiology of cartilage and synovium. Br J Rheumatol 1996;35(suppl 3):10-13.
-
(1996)
Br J Rheumatol
, vol.35
, Issue.SUPPL. 3
, pp. 10-13
-
-
Freemont, A.J.1
-
4
-
-
0036204872
-
Current understanding of cellular and molecular events in intervertebral disc degeneration: Implications for therapy
-
Freemont AJ, Watkins A, Le Maitre C, Jeziorska M, Hoyland JA. Current understanding of cellular and molecular events in intervertebral disc degeneration: implications for therapy. J Pathol 2002;196(4):374-379.
-
(2002)
J Pathol
, vol.196
, Issue.4
, pp. 374-379
-
-
Freemont, A.J.1
Watkins, A.2
Le Maitre, C.3
Jeziorska, M.4
Hoyland, J.A.5
-
5
-
-
0345688738
-
The pathophysiology of osteoarthritis
-
Iannone F, Lapadula G. The pathophysiology of osteoarthritis. Aging Clin Exp Res 2003;15(5):364-372.
-
(2003)
Aging Clin Exp Res
, vol.15
, Issue.5
, pp. 364-372
-
-
Iannone, F.1
Lapadula, G.2
-
6
-
-
0037006148
-
Aging of the elastic and collagen fibers in the human cervical interspinous ligaments
-
Barros EM, Rodrigues CJ, Rodrigues NR, Oliveira RP, Barros TE, Rodrigues AJ, Jr. Aging of the elastic and collagen fibers in the human cervical interspinous ligaments. Spine J 2002;2(1):57-62.
-
(2002)
Spine J
, vol.2
, Issue.1
, pp. 57-62
-
-
Barros, E.M.1
Rodrigues, C.J.2
Rodrigues, N.R.3
Oliveira, R.P.4
Barros, T.E.5
Rodrigues Jr., A.J.6
-
7
-
-
16544383328
-
Age-related changes in human PCLs: A light and electron microscopic study
-
Sargon MF, Doral MN, Atay OA. Age-related changes in human PCLs: a light and electron microscopic study. Knee Surg Sports Traumatol Arthrosc 2004;12(4):280-284.
-
(2004)
Knee Surg Sports Traumatol Arthrosc
, vol.12
, Issue.4
, pp. 280-284
-
-
Sargon, M.F.1
Doral, M.N.2
Atay, O.A.3
-
8
-
-
0023856536
-
What is the cause of the ageing atrophy? Total number, size and proportion of different fiber types studied in whole vastus lateralis muscle from 15- to 83-year-old men
-
Lexell J, Taylor CC, Sjostrom M. What is the cause of the ageing atrophy? Total number, size and proportion of different fiber types studied in whole vastus lateralis muscle from 15- to 83-year-old men. J Neurol Sci 1988;84(2-3):275-294.
-
(1988)
J Neurol Sci
, vol.84
, Issue.2-3
, pp. 275-294
-
-
Lexell, J.1
Taylor, C.C.2
Sjostrom, M.3
-
9
-
-
6944224363
-
Growth factors and muscle ageing
-
Goldspink G, Harridge SDR. Growth factors and muscle ageing. Exp Gerontol 2004;39(10):1433-1438.
-
(2004)
Exp Gerontol
, vol.39
, Issue.10
, pp. 1433-1438
-
-
Goldspink, G.1
Harridge, S.D.R.2
-
10
-
-
0037927688
-
Catabolism of aging: Is it an inflammatory process?
-
Roubenoff R. Catabolism of aging: is it an inflammatory process? Curr Opin Clin Nutr Metab Care 2003;6(3):295-299.
-
(2003)
Curr Opin Clin Nutr Metab Care
, vol.6
, Issue.3
, pp. 295-299
-
-
Roubenoff, R.1
-
11
-
-
0033924298
-
Lipid metabolism in the elderly
-
Toth MJ, Tchernof A. Lipid metabolism in the elderly. Eur J Clin Nutr 2000;54(suppl 3):S121-125.
-
(2000)
Eur J Clin Nutr
, vol.54
, Issue.SUPPL. 3
-
-
Toth, M.J.1
Tchernof, A.2
-
12
-
-
0030754240
-
Preadipocyte function and aging: Links between age-related changes in cell dynamics and altered fat tissue function
-
Kirkland JL, Dobson DE. Preadipocyte function and aging: links between age-related changes in cell dynamics and altered fat tissue function, J Am Geriatr Soc 1997;45(8):959-967.
-
(1997)
J Am Geriatr Soc
, vol.45
, Issue.8
, pp. 959-967
-
-
Kirkland, J.L.1
Dobson, D.E.2
-
13
-
-
0036604165
-
Adipogenesis and aging: Does aging make fat go MAD?
-
Kirkland JL, Tchkonia T, Pirtskhalava T, Han J, Karagiannides I. Adipogenesis and aging: does aging make fat go MAD? Exp Gerontol 2002;37(6):757-767.
-
(2002)
Exp Gerontol
, vol.37
, Issue.6
, pp. 757-767
-
-
Kirkland, J.L.1
Tchkonia, T.2
Pirtskhalava, T.3
Han, J.4
Karagiannides, I.5
-
14
-
-
0032401898
-
Mechanism of maturation and ageing of collagen
-
Bailey AJ, Paul RG, Knott L. Mechanism of maturation and ageing of collagen. Mech Ageing Dev 1998;106(1-2):1-56.
-
(1998)
Mech Ageing Dev
, vol.106
, Issue.1-2
, pp. 1-56
-
-
Bailey, A.J.1
Paul, R.G.2
Knott, L.3
-
15
-
-
0018078702
-
The structure of pyridinoline, a collagen cross-link
-
Fujimoto D, Ishida T, Hayashi H. The structure of pyridinoline, a collagen cross-link. Biochem Biophys Res Commun 1978;84(1):52-57.
-
(1978)
Biochem Biophys Res Commun
, vol.84
, Issue.1
, pp. 52-57
-
-
Fujimoto, D.1
Ishida, T.2
Hayashi, H.3
-
16
-
-
0026545182
-
Identification of the loci of the collagen-associated Ehrlich chromagen in type I collagen confirms its role as a trivalent cross-link
-
Kuypers R, Tyler M, Kurth LB, Jenkins ID, Horgan DJ. Identification of the loci of the collagen-associated Ehrlich chromagen in type I collagen confirms its role as a trivalent cross-link. Biochem J 1992;283(1):129-136.
-
(1992)
Biochem J
, vol.283
, Issue.1
, pp. 129-136
-
-
Kuypers, R.1
Tyler, M.2
Kurth, L.B.3
Jenkins, I.D.4
Horgan, D.J.5
-
17
-
-
0032032089
-
Collagen cross-links in mineralising tissue: A review of theirchemistry, function and clinical relevance
-
Knott L, Bailey AJ. Collagen cross-links in mineralising tissue: a review of theirchemistry, function and clinical relevance. Bone 1998;22(3):181-187.
-
(1998)
Bone
, vol.22
, Issue.3
, pp. 181-187
-
-
Knott, L.1
Bailey, A.J.2
-
18
-
-
0021329505
-
Collagen aging in vitro by nonenzymatic glycosylation and browning
-
Kohn RR, Cerami A, Monnier VM. Collagen aging in vitro by nonenzymatic glycosylation and browning. Diabetes 1984;33(1): 57-59.
-
(1984)
Diabetes
, vol.33
, Issue.1
, pp. 57-59
-
-
Kohn, R.R.1
Cerami, A.2
Monnier, V.M.3
-
19
-
-
0025732948
-
The role of oxidative stress in the development of complications in diabetes
-
Baynes JW. The role of oxidative stress in the development of complications in diabetes. Diabetes 1991;40(4):405-412.
-
(1991)
Diabetes
, vol.40
, Issue.4
, pp. 405-412
-
-
Baynes, J.W.1
-
20
-
-
0027970304
-
Advanced glycation end-products induce sclerosis and albuminurea in normal rats
-
Vlassara H, Striker LJ, Teichberg S, Fuh H, Li YM, Steffes M. Advanced glycation end-products induce sclerosis and albuminurea in normal rats. Proc Natl Acad Sci USA 1994;91(24): 11704-11708.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, Issue.24
, pp. 11704-11708
-
-
Vlassara, H.1
Striker, L.J.2
Teichberg, S.3
Fuh, H.4
Li, Y.M.5
Steffes, M.6
-
21
-
-
0033002442
-
The effect of advanced glycation end-product formation upon cell-matrix interactions
-
Paul RG, Bailey AJ. The effect of advanced glycation end-product formation upon cell-matrix interactions. Int J Biochem Cell Biol 1999;31(6):653-660.
-
(1999)
Int J Biochem Cell Biol
, vol.31
, Issue.6
, pp. 653-660
-
-
Paul, R.G.1
Bailey, A.J.2
-
22
-
-
0029777555
-
Interactions of elastin and aorta with sugars in vitro and their effects on the biochemical and physical properties
-
Winlove CP, Parker KH, Avery NC, Bailey AJ. Interactions of elastin and aorta with sugars in vitro and their effects on the biochemical and physical properties. Diabetologia 1996;39(10):1131-1139.
-
(1996)
Diabetologia
, vol.39
, Issue.10
, pp. 1131-1139
-
-
Winlove, C.P.1
Parker, K.H.2
Avery, N.C.3
Bailey, A.J.4
-
23
-
-
0346242689
-
Elasticity in extracellular matrix 'shape modules' of tendon, cartilage, etc. A sliding proteoglycan-filament model
-
Scott JE. Elasticity in extracellular matrix 'shape modules' of tendon, cartilage, etc. A sliding proteoglycan-filament model. J Physiol 2003;553(2):335-343.
-
(2003)
J Physiol
, vol.553
, Issue.2
, pp. 335-343
-
-
Scott, J.E.1
-
24
-
-
33746305577
-
Cartilage elasticity resides in shape module decoran and aggrecan sumps of damping fluid: Implications in osteoarthrosis
-
Scott JE, Stockwell RA. Cartilage elasticity resides in shape module decoran and aggrecan sumps of damping fluid: implications in osteoarthrosis. J Physiol 2006;574(3):643-650.
-
(2006)
J Physiol
, vol.574
, Issue.3
, pp. 643-650
-
-
Scott, J.E.1
Stockwell, R.A.2
-
25
-
-
0036398455
-
Aging, articular cartilage chondrocyte senescence and osteoarthritis
-
Martin JA, Buckwalter JA. Aging, articular cartilage chondrocyte senescence and osteoarthritis. Biogerontology 2002;3(5):257-264.
-
(2002)
Biogerontology
, vol.3
, Issue.5
, pp. 257-264
-
-
Martin, J.A.1
Buckwalter, J.A.2
-
26
-
-
27144473960
-
Aggrecan, aging and assembly in articular cartilage
-
Dudhia J. Aggrecan, aging and assembly in articular cartilage. Cell Mol Life Sci 2005;62(19-20):2241-2256.
-
(2005)
Cell Mol Life Sci
, vol.62
, Issue.19-20
, pp. 2241-2256
-
-
Dudhia, J.1
-
27
-
-
14844362345
-
Biology of intervertebral disc aging and degeneration: Involvement of the extracellular matrix
-
Roughley PJ. Biology of intervertebral disc aging and degeneration: involvement of the extracellular matrix. Spine 2004;29(23): 2691-2699.
-
(2004)
Spine
, vol.29
, Issue.23
, pp. 2691-2699
-
-
Roughley, P.J.1
-
28
-
-
4544272466
-
Localization of degradative enzymes and their inhibitors in the degenerate human intervertebral disc
-
Le Maitre CL, Freemont AJ, Hoyland JA. Localization of degradative enzymes and their inhibitors in the degenerate human intervertebral disc. J Pathol 2004;204(1):47-54.
-
(2004)
J Pathol
, vol.204
, Issue.1
, pp. 47-54
-
-
Le Maitre, C.L.1
Freemont, A.J.2
Hoyland, J.A.3
-
29
-
-
0030763570
-
Gene expression of matrix metalloproteinases 1, 3, and 9 by chondrocytes in osteoarthritic human knee articular cartilage is zone and grade specific
-
Freemont AJ, Hampson V, Tilman R, Goupille P, Taiwo Y, Hoyland JA. Gene expression of matrix metalloproteinases 1, 3, and 9 by chondrocytes in osteoarthritic human knee articular cartilage is zone and grade specific. Ann Rheum Dis 1997;56(9):542-549.
-
(1997)
Ann Rheum Dis
, vol.56
, Issue.9
, pp. 542-549
-
-
Freemont, A.J.1
Hampson, V.2
Tilman, R.3
Goupille, P.4
Taiwo, Y.5
Hoyland, J.A.6
-
30
-
-
13444256201
-
Aging bone and cartilage: Cross-cutting issues
-
Carrington JL. Aging bone and cartilage: cross-cutting issues. Biochem Biophys Res Commun 2005;328(3):700-708.
-
(2005)
Biochem Biophys Res Commun
, vol.328
, Issue.3
, pp. 700-708
-
-
Carrington, J.L.1
-
31
-
-
0035811073
-
Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production
-
Flurkey K, Papaconstantinou J, Miller RA, Harrison DE. Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production. Proc Natl Acad Sci USA 2001;98(12):6736-6741.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.12
, pp. 6736-6741
-
-
Flurkey, K.1
Papaconstantinou, J.2
Miller, R.A.3
Harrison, D.E.4
-
32
-
-
0033450849
-
Pleiotropic effects of growth hormone and insulin-like growth factor (IGF)-1 on biological aging: Inferences from moderate caloric-restricted animals
-
Sonntag WE, Lynch CD, Cefalu WT, Ingram RL, Bennett SA, Thornton PL, et al. Pleiotropic effects of growth hormone and insulin-like growth factor (IGF)-1 on biological aging: inferences from moderate caloric-restricted animals. J Gerontol A Biol Sci Med Sci 1999;54(12):B521-B538.
-
(1999)
J Gerontol A Biol Sci Med Sci
, vol.54
, Issue.12
-
-
Sonntag, W.E.1
Lynch, C.D.2
Cefalu, W.T.3
Ingram, R.L.4
Bennett, S.A.5
Thornton, P.L.6
-
33
-
-
0031193785
-
Age-related decline in chondrocyte response to insulin-like growth factor-I: The role of growth factor binding proteins
-
Martin JA, Ellerbroek SM, Buckwalter JA. Age-related decline in chondrocyte response to insulin-like growth factor-I: the role of growth factor binding proteins. J Orthop Res 1997;15(4):491-498.
-
(1997)
J Orthop Res
, vol.15
, Issue.4
, pp. 491-498
-
-
Martin, J.A.1
Ellerbroek, S.M.2
Buckwalter, J.A.3
-
34
-
-
0034043240
-
Growth hormone and aging
-
Rosen CJ. Growth hormone and aging. Endocrine 2000;12(2): 197-201.
-
(2000)
Endocrine
, vol.12
, Issue.2
, pp. 197-201
-
-
Rosen, C.J.1
-
35
-
-
27944439283
-
Aging somatotropic axis: Mechanisms and implications of insulin-like growth factor-related binding protein adaptation
-
Frystyk J. Aging somatotropic axis: mechanisms and implications of insulin-like growth factor-related binding protein adaptation. Endocrinol Metab Clin North Am 2005;34(4):865-876.
-
(2005)
Endocrinol Metab Clin North Am
, vol.34
, Issue.4
, pp. 865-876
-
-
Frystyk, J.1
-
36
-
-
33645813121
-
Somatopause: Dismetabolic and bone effects
-
Lombardi G, Tauchmanova L, Di Somma C, Musella T, Rota F, Savanelli MC, et al. Somatopause: dismetabolic and bone effects. J Endocrinol Invest 2005;28(10 suppl):36-42.
-
(2005)
J Endocrinol Invest
, vol.28
, Issue.10 SUPPL.
, pp. 36-42
-
-
Lombardi, G.1
Tauchmanova, L.2
Di Somma, C.3
Musella, T.4
Rota, F.5
Savanelli, M.C.6
-
37
-
-
0346500576
-
Pathophysiological and clinical importance of insulin-like growth factor-I with respect to bone metabolism
-
Z̧ofková I. Pathophysiological and clinical importance of insulin-like growth factor-I with respect to bone metabolism. Physiol Res 2003;52(6):657-679.
-
(2003)
Physiol Res
, vol.52
, Issue.6
, pp. 657-679
-
-
Z̧ofková, I.1
-
38
-
-
0032462949
-
Benefits of growth hormone treatment on bone metabolism, bone density and bone strength in growth hormone deficiency and osteoporosis
-
Wuster C, Harle U, Rehn U, Muller C, Knauf K, Koppler D, et al. Benefits of growth hormone treatment on bone metabolism, bone density and bone strength in growth hormone deficiency and osteoporosis. Growth Horm IGF Res 1998;8(suppl A):87-94.
-
(1998)
Growth Horm IGF Res
, vol.8
, Issue.SUPPL. A
, pp. 87-94
-
-
Wuster, C.1
Harle, U.2
Rehn, U.3
Muller, C.4
Knauf, K.5
Koppler, D.6
-
39
-
-
0032907148
-
Age-related changes in the synthesis of link protein and aggrecan in human articular cartilage: Implications for aggregate stability
-
Bolton MC, Dudhia J, Bayliss MT. Age-related changes in the synthesis of link protein and aggrecan in human articular cartilage: implications for aggregate stability. Biochem J 1999;337(1):77-82.
-
(1999)
Biochem J
, vol.337
, Issue.1
, pp. 77-82
-
-
Bolton, M.C.1
Dudhia, J.2
Bayliss, M.T.3
-
40
-
-
0033680154
-
Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis: Studies in a non-human primate model of naturally occurring disease
-
Loeser RF, Shanker G, Carlson CS, Gardin JF, Shelton BJ, Sonntag WE. Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis: studies in a non-human primate model of naturally occurring disease. Arthritis Rheum 2000;43:2110-2120.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 2110-2120
-
-
Loeser, R.F.1
Shanker, G.2
Carlson, C.S.3
Gardin, J.F.4
Shelton, B.J.5
Sonntag, W.E.6
-
41
-
-
0036745073
-
Detection of nitrotyrosine in aging and osteoarthritic cartilage: Correlation of oxidative damage with the presence of interleukin-1β and with chondrocyte resistance to insulin-like growth factor 1
-
Loeser RF, Carlson CS, Del Carlo M, Cole A. Detection of nitrotyrosine in aging and osteoarthritic cartilage: correlation of oxidative damage with the presence of interleukin-1β and with chondrocyte resistance to insulin-like growth factor 1. Arthritis Rheum 2002;46(9):2349-2357.
-
(2002)
Arthritis Rheum
, vol.46
, Issue.9
, pp. 2349-2357
-
-
Loeser, R.F.1
Carlson, C.S.2
Del Carlo, M.3
Cole, A.4
-
42
-
-
0029994462
-
Skeletal muscle growth of oMTIa-oGH transgenic mice
-
Sharma A, Lee YB, Murray JD, Oberbauer AM. Skeletal muscle growth of oMTIa-oGH transgenic mice. Growth Dev Aging 1996;60(1):31-41.
-
(1996)
Growth Dev Aging
, vol.60
, Issue.1
, pp. 31-41
-
-
Sharma, A.1
Lee, Y.B.2
Murray, J.D.3
Oberbauer, A.M.4
-
43
-
-
0025368959
-
Effects of human growth hormone in men over 60 years old
-
Rudman D, Feller AG, Nagraj HS, Gergans GA, Lalitha PY, Goldberg AF, et al. Effects of human growth hormone in men over 60 years old. N Engl J Med 1990;323(1): 1-6.
-
(1990)
N Engl J Med
, vol.323
, Issue.1
, pp. 1-6
-
-
Rudman, D.1
Feller, A.G.2
Nagraj, H.S.3
Gergans, G.A.4
Lalitha, P.Y.5
Goldberg, A.F.6
-
44
-
-
0033560860
-
Expression of insulin growth factor-1 splice variants and structural genes in rabbit skeletal muscle induced by stretch and stimulation
-
McKoy G, Ashley W, Mander J, Yang SY, Williams N, Russell B, et al. Expression of insulin growth factor-1 splice variants and structural genes in rabbit skeletal muscle induced by stretch and stimulation. J Physiol 1999;516(2):583-592.
-
(1999)
J Physiol
, vol.516
, Issue.2
, pp. 583-592
-
-
McKoy, G.1
Ashley, W.2
Mander, J.3
Yang, S.Y.4
Williams, N.5
Russell, B.6
-
45
-
-
1542269757
-
The effect of recombinant human growth hormone and resistance training on IGF-I mRNA expression in the muscles of elderly men
-
Hameed M, Lange KHW, Andersen JL, Schjerling P, Kjaer M, Harridge SDR, et al. The effect of recombinant human growth hormone and resistance training on IGF-I mRNA expression in the muscles of elderly men. J Physiol 2004;555(1):231-240.
-
(2004)
J Physiol
, vol.555
, Issue.1
, pp. 231-240
-
-
Hameed, M.1
Lange, K.H.W.2
Andersen, J.L.3
Schjerling, P.4
Kjaer, M.5
Harridge, S.D.R.6
-
46
-
-
0035086416
-
Osteoporosis in men: A cellular endocrine perspective of an increasingly common clinical problem
-
Byers RJ, Hoyland JA, Braidman IP. Osteoporosis in men: a cellular endocrine perspective of an increasingly common clinical problem. J Endocrinol 2001;168(3):353-362.
-
(2001)
J Endocrinol
, vol.168
, Issue.3
, pp. 353-362
-
-
Byers, R.J.1
Hoyland, J.A.2
Braidman, I.P.3
-
47
-
-
0034890081
-
Relationship of serum sex steroid levels to longitudinal changes in bone density in young versus elderly men
-
Khosla S, Melton III LJ, Atkinson EJ, O'Fallon WM. Relationship of serum sex steroid levels to longitudinal changes in bone density in young versus elderly men. J Clin Endocrinol Metab 2001;86(8):3555-3561.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, Issue.8
, pp. 3555-3561
-
-
Khosla, S.1
Melton III, L.J.2
Atkinson, E.J.3
O'Fallon, W.M.4
-
48
-
-
0033832459
-
Preliminary report of impaired oestrogen receptor-alpha expression in bone, but no involvement of androgen receptor, in male idiopathic osteoporosis
-
Braidman IP, Baris C, Selby PL, Adams JE, Freemont AJ, Hoyland JA. Preliminary report of impaired oestrogen receptor-alpha expression in bone, but no involvement of androgen receptor, in male idiopathic osteoporosis. J Pathol 2000;192(1):90-96.
-
(2000)
J Pathol
, vol.192
, Issue.1
, pp. 90-96
-
-
Braidman, I.P.1
Baris, C.2
Selby, P.L.3
Adams, J.E.4
Freemont, A.J.5
Hoyland, J.A.6
-
49
-
-
0035139617
-
Localization of estrogen receptor beta protein expression in adult human bone
-
Braidman IP, Hainey L, Batra G, Selby PL, Saunders PT, Hoyland JA. Localization of estrogen receptor beta protein expression in adult human bone. J Bone Miner Res 2001;16(2):214-220.
-
(2001)
J Bone Miner Res
, vol.16
, Issue.2
, pp. 214-220
-
-
Braidman, I.P.1
Hainey, L.2
Batra, G.3
Selby, P.L.4
Saunders, P.T.5
Hoyland, J.A.6
-
50
-
-
0037649062
-
Related evidence for cell-specific changes with age in expression of oestrogen receptor (ER) alpha and beta in bone fractures from men and women
-
Batra GS, Hainey L, Freemont AJ, Andrew G, Saunders PT, Hoyland JA, et al. Related evidence for cell-specific changes with age in expression of oestrogen receptor (ER) alpha and beta in bone fractures from men and women. J Pathol 2003;200(1):65-73.
-
(2003)
J Pathol
, vol.200
, Issue.1
, pp. 65-73
-
-
Batra, G.S.1
Hainey, L.2
Freemont, A.J.3
Andrew, G.4
Saunders, P.T.5
Hoyland, J.A.6
-
51
-
-
21344447765
-
Factors influencing longitudinal change in knee cartilage volume measured from magnetic resonance imaging in healthy men
-
Hanna F, Ebeling PR, Wang Y, O'Sullivan R, Davis S, Wluka AE, et al. Factors influencing longitudinal change in knee cartilage volume measured from magnetic resonance imaging in healthy men. Ann Rheum Dis 2005;64(7):1038-1042.
-
(2005)
Ann Rheum Dis
, vol.64
, Issue.7
, pp. 1038-1042
-
-
Hanna, F.1
Ebeling, P.R.2
Wang, Y.3
O'Sullivan, R.4
Davis, S.5
Wluka, A.E.6
-
52
-
-
0031229565
-
Primary immunolocalization of androgen target cells in the human anterior cruciate ligament
-
Hamlet WP. Liu SH, Panossian V, Finerman GA. Primary immunolocalization of androgen target cells in the human anterior cruciate ligament. J Orthop Res 1997;15(5):657-663.
-
(1997)
J Orthop Res
, vol.15
, Issue.5
, pp. 657-663
-
-
Hamlet, W.P.1
Liu, S.H.2
Panossian, V.3
Finerman, G.A.4
-
53
-
-
0030198692
-
Primary immunolocalization of estrogen and progesterone target cells in the human anterior cruciate ligament
-
Liu SH, al-Shaikh R, Panossian V, Yang RS, Nelson SD, Soleiman N, et al. Primary immunolocalization of estrogen and progesterone target cells in the human anterior cruciate ligament. J Orthop Res 1996;14(4):526-533.
-
(1996)
J Orthop Res
, vol.14
, Issue.4
, pp. 526-533
-
-
Liu, S.H.1
al-Shaikh, R.2
Panossian, V.3
Yang, R.S.4
Nelson, S.D.5
Soleiman, N.6
-
54
-
-
29744447597
-
The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration
-
Le Maitre CL, Freemont AJ, Hoyland JA. The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration. Arthritis Res Ther 2005;7(4):R732-745.
-
(2005)
Arthritis Res Ther
, vol.7
, Issue.4
-
-
Le Maitre, C.L.1
Freemont, A.J.2
Hoyland, J.A.3
-
55
-
-
33644951210
-
A preliminary in vitro study into the use of IL-1Ra gene therapy for the inhibition of intervertebral disc degeneration
-
Le Maitre CL, Freemont AJ, Hoyland JA. A preliminary in vitro study into the use of IL-1Ra gene therapy for the inhibition of intervertebral disc degeneration, Int J Exp Pathol 2006;87(1):17-28.
-
(2006)
Int J Exp Pathol
, vol.87
, Issue.1
, pp. 17-28
-
-
Le Maitre, C.L.1
Freemont, A.J.2
Hoyland, J.A.3
-
56
-
-
0026497223
-
Increase of plasma IL-6 concentration with age in healthy subjects
-
Wei J, Xu H, Davies JL, Hemmings GP. Increase of plasma IL-6 concentration with age in healthy subjects. Life Sci 1992;51(25):1953-1956.
-
(1992)
Life Sci
, vol.51
, Issue.25
, pp. 1953-1956
-
-
Wei, J.1
Xu, H.2
Davies, J.L.3
Hemmings, G.P.4
-
57
-
-
0027162602
-
Altered regulation of IL-6 production with normal aging. Possible linkage to the age-associated decline in dehydroepiandrosterone and its sulfated derivative
-
Daynes RA, Araneo BA, Ershler WB, Maloney C, Li GZ, Ryu SY. Altered regulation of IL-6 production with normal aging. Possible linkage to the age-associated decline in dehydroepiandrosterone and its sulfated derivative. J Immunol 1993;150(12):5219-5230.
-
(1993)
J Immunol
, vol.150
, Issue.12
, pp. 5219-5230
-
-
Daynes, R.A.1
Araneo, B.A.2
Ershler, W.B.3
Maloney, C.4
Li, G.Z.5
Ryu, S.Y.6
-
58
-
-
33646902419
-
Inflammatory markers and loss of muscle mass (sarcopenia) and strength
-
Schaap LA, Pluijm SM, Deeg DJ, Visser M. Inflammatory markers and loss of muscle mass (sarcopenia) and strength. Am J Med 2006;119(6):526.e9-17.
-
(2006)
Am J Med
, vol.119
, Issue.6
-
-
Schaap, L.A.1
Pluijm, S.M.2
Deeg, D.J.3
Visser, M.4
-
59
-
-
0042734423
-
The role of chondrocyte senescence in osteoarthritis
-
Price JS, Waters JG, Darrah C, Pennington C, Edwards DR, Donell ST, et al. The role of chondrocyte senescence in osteoarthritis. Aging Cell 2002;1(1):57-65.
-
(2002)
Aging Cell
, vol.1
, Issue.1
, pp. 57-65
-
-
Price, J.S.1
Waters, J.G.2
Darrah, C.3
Pennington, C.4
Edwards, D.R.5
Donell, S.T.6
-
60
-
-
4644250302
-
From cells to ageing: A review of models and mechanisms of cellular senescence and their impact on human ageing
-
Magalhâes JP. From cells to ageing: a review of models and mechanisms of cellular senescence and their impact on human ageing. Exp Cell Res 2004;300(1):1-10.
-
(2004)
Exp Cell Res
, vol.300
, Issue.1
, pp. 1-10
-
-
Magalhâes, J.P.1
-
61
-
-
0033455559
-
Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death
-
Herbert B, Pitts AE, Baker SI, Hamilton SE, Wright WE, Shay JW, et al. Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death. Proc Natl Acad Sci USA 1999;96(25):14276-14281.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.25
, pp. 14276-14281
-
-
Herbert, B.1
Pitts, A.E.2
Baker, S.I.3
Hamilton, S.E.4
Wright, W.E.5
Shay, J.W.6
-
62
-
-
0033732110
-
Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes
-
Toussaint O, Medrano EE, von Zglinicki T. Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes. Exp Gerontol 2000;35(8):927-945.
-
(2000)
Exp Gerontol
, vol.35
, Issue.8
, pp. 927-945
-
-
Toussaint, O.1
Medrano, E.E.2
von Zglinicki, T.3
-
63
-
-
33644899652
-
Catabolic stress induces features of chondrocyte senescence through over-expression of caveolin 1: Possible involvement of caveolin 1-induced down-regulation of articular chondrocytes in the pathogenesis of osteoarthritis
-
Dai SM, Shan ZZ, Nakamura H, Masuko-Hongo K, Kato T, Nishioka K, et al. Catabolic stress induces features of chondrocyte senescence through over-expression of caveolin 1: possible involvement of caveolin 1-induced down-regulation of articular chondrocytes in the pathogenesis of osteoarthritis. Arthritis Rheum 2006;54(3):818-831.
-
(2006)
Arthritis Rheum
, vol.54
, Issue.3
, pp. 818-831
-
-
Dai, S.M.1
Shan, Z.Z.2
Nakamura, H.3
Masuko-Hongo, K.4
Kato, T.5
Nishioka, K.6
-
64
-
-
16244403047
-
Increased caveolin-1, a cause for the declined adipogenic potential of senescent human mesenchymal stem cells
-
Park JS, Kim HY, Kim HW, Chae GN, Oh HT, Park JY, et al. Increased caveolin-1, a cause for the declined adipogenic potential of senescent human mesenchymal stem cells. Mech Ageing Dev 2005;126(5):551-559.
-
(2005)
Mech Ageing Dev
, vol.126
, Issue.5
, pp. 551-559
-
-
Park, J.S.1
Kim, H.Y.2
Kim, H.W.3
Chae, G.N.4
Oh, H.T.5
Park, J.Y.6
-
65
-
-
1542269027
-
Circulating mesenchymal stem cells
-
Roufosse CA, Direkze NC, Otto WR, Wright NA. Circulating mesenchymal stem cells. Int J Biochem Cell Biol 2004;36(4):585-597.
-
(2004)
Int J Biochem Cell Biol
, vol.36
, Issue.4
, pp. 585-597
-
-
Roufosse, C.A.1
Direkze, N.C.2
Otto, W.R.3
Wright, N.A.4
-
66
-
-
33646078934
-
Bloodstream cells phenotypically identical to human mesenchymal bone marrow stem cells circulate in large amounts under the influence of acute large skin damage: New evidence for their use in regenerative medicine
-
Mansilla E, Marin GH, Drago H, Sturla F, Salas E, Gardiner C, et al. Bloodstream cells phenotypically identical to human mesenchymal bone marrow stem cells circulate in large amounts under the influence of acute large skin damage: new evidence for their use in regenerative medicine. Transplant Proc 2006;38(3):967-969.
-
(2006)
Transplant Proc
, vol.38
, Issue.3
, pp. 967-969
-
-
Mansilla, E.1
Marin, G.H.2
Drago, H.3
Sturla, F.4
Salas, E.5
Gardiner, C.6
-
67
-
-
2342613539
-
Controlling the balance between osteoblastogenesis and adipogenesis and the consequent therapeutic implications
-
Nuttall ME, Gimble JM. Controlling the balance between osteoblastogenesis and adipogenesis and the consequent therapeutic implications. Curr Opin Pharmacol 2004;4(3):290-294.
-
(2004)
Curr Opin Pharmacol
, vol.4
, Issue.3
, pp. 290-294
-
-
Nuttall, M.E.1
Gimble, J.M.2
-
68
-
-
0030842836
-
Differential patterns of osteoblast dysfunction in trabecular bone in patients with established osteoporosis
-
Byers RJ, Denton J, Hoyland JA, Freemont AJ. Differential patterns of osteoblast dysfunction in trabecular bone in patients with established osteoporosis. J Clin Pathol 1997;50(9):760-764.
-
(1997)
J Clin Pathol
, vol.50
, Issue.9
, pp. 760-764
-
-
Byers, R.J.1
Denton, J.2
Hoyland, J.A.3
Freemont, A.J.4
-
69
-
-
2342613539
-
Controlling the balance between osteoblastogenesis and adipogenesis and the consequent therapeutic implications
-
Nuttall ME, Gimble JM. Controlling the balance between osteoblastogenesis and adipogenesis and the consequent therapeutic implications. Curr Opin Pharmacol 2004;4(3):290-294.
-
(2004)
Curr Opin Pharmacol
, vol.4
, Issue.3
, pp. 290-294
-
-
Nuttall, M.E.1
Gimble, J.M.2
-
70
-
-
0036090467
-
Divergent effects of selective peroxisome proliferator-activated receptor-gamma 2 ligands on adipocyte versus osteoblast differentiation
-
Lecka-Czernik B, Moerman EJ, Grant DF, Lehmann JM, Manolagas SC, Jilka RL. Divergent effects of selective peroxisome proliferator-activated receptor-gamma 2 ligands on adipocyte versus osteoblast differentiation. Endocrinology 2002;143(6): 2376-2384.
-
(2002)
Endocrinology
, vol.143
, Issue.6
, pp. 2376-2384
-
-
Lecka-Czernik, B.1
Moerman, E.J.2
Grant, D.F.3
Lehmann, J.M.4
Manolagas, S.C.5
Jilka, R.L.6
-
71
-
-
0034637103
-
Inhibition of adipogenesis by Wnt signaling
-
Ross SE, Hemati N, Longo KA, Bennett CN, Lucas PC, Erickson RL, et al. Inhibition of adipogenesis by Wnt signaling. Science 2000;289(5481):950-953.
-
(2000)
Science
, vol.289
, Issue.5481
, pp. 950-953
-
-
Ross, S.E.1
Hemati, N.2
Longo, K.A.3
Bennett, C.N.4
Lucas, P.C.5
Erickson, R.L.6
-
72
-
-
25444478907
-
Aging, stem cells and tissue regeneration: Lessons from muscle
-
Conboy IM, Rando TA. Aging, stem cells and tissue regeneration: lessons from muscle. Cell Cycle 2005;4(3):407-410.
-
(2005)
Cell Cycle
, vol.4
, Issue.3
, pp. 407-410
-
-
Conboy, I.M.1
Rando, T.A.2
-
73
-
-
2942651287
-
Cell mechanics and mechanotransduction: Pathways, probes, and physiology
-
Huang H, Kamm RD, Lee RT. Cell mechanics and mechanotransduction: pathways, probes, and physiology. Am J Physiol Cell Physiol 2004;287(1):C1-11.
-
(2004)
Am J Physiol Cell Physiol
, vol.287
, Issue.1
-
-
Huang, H.1
Kamm, R.D.2
Lee, R.T.3
-
74
-
-
0026350711
-
Effects of mechanical load on cartilage matrix biosynthesis in vitro
-
Larsson T, Aspden RM, Heinegård D. Effects of mechanical load on cartilage matrix biosynthesis in vitro. Matrix 1991;11(6):388-394.
-
(1991)
Matrix
, vol.11
, Issue.6
, pp. 388-394
-
-
Larsson, T.1
Aspden, R.M.2
Heinegård, D.3
-
75
-
-
27944455991
-
The response of elderly human articular cartilage to mechanical stimuli in vitro
-
Plumb MS, Aspden RM. The response of elderly human articular cartilage to mechanical stimuli in vitro. Osteoarthr Cartilage 2005;13(12):1084-1091.
-
(2005)
Osteoarthr Cartilage
, vol.13
, Issue.12
, pp. 1084-1091
-
-
Plumb, M.S.1
Aspden, R.M.2
-
76
-
-
33646516830
-
Competing regulation of matrix biosynthesis by mechanical and IGF-1 signalling in elderly human articular cartilage in vitro
-
Plumb MS, Treon K, Aspden RM. Competing regulation of matrix biosynthesis by mechanical and IGF-1 signalling in elderly human articular cartilage in vitro. Biochim Biophys Acta 2006;1760(5):762-767.
-
(2006)
Biochim Biophys Acta
, vol.1760
, Issue.5
, pp. 762-767
-
-
Plumb, M.S.1
Treon, K.2
Aspden, R.M.3
-
77
-
-
0034802113
-
Functional decline in aging and disease: A role for apoptosis
-
Joaquin AM, Gollapudi S. Functional decline in aging and disease: a role for apoptosis. J Am Geriatr Soc 2001;49(9):1234-1240.
-
(2001)
J Am Geriatr Soc
, vol.49
, Issue.9
, pp. 1234-1240
-
-
Joaquin, A.M.1
Gollapudi, S.2
-
78
-
-
1642473148
-
Cell death in cartilage
-
Kuhn K, D'Lima DD, Hashimoto S, Lotz M. Cell death in cartilage. Osteoarthr Cartilage 2004;12(1):1-16.
-
(2004)
Osteoarthr Cartilage
, vol.12
, Issue.1
, pp. 1-16
-
-
Kuhn, K.1
D'Lima, D.D.2
Hashimoto, S.3
Lotz, M.4
-
79
-
-
5444259084
-
The regulation of chondrocyte function by proinflammatory mediators: Prostaglandins and nitric oxide
-
Goldring MB, Berenbaum F. The regulation of chondrocyte function by proinflammatory mediators: prostaglandins and nitric oxide. Clin Orthop Relat Res 2004;427:(suppl): S37-46.
-
(2004)
Clin Orthop Relat Res
, vol.427
, Issue.SUPPL.
-
-
Goldring, M.B.1
Berenbaum, F.2
-
80
-
-
0036182992
-
Integrins and stretch activated ion channels; putative components of functional cell surface mechanoreceptors in articular chondrocytes
-
Mobasheri A, Carter SD, Martin-Vasallo P, Shakibaei M. Integrins and stretch activated ion channels; putative components of functional cell surface mechanoreceptors in articular chondrocytes. Cell Biol Int 2002;26(1):1-18.
-
(2002)
Cell Biol Int
, vol.26
, Issue.1
, pp. 1-18
-
-
Mobasheri, A.1
Carter, S.D.2
Martin-Vasallo, P.3
Shakibaei, M.4
-
81
-
-
0031915678
-
Chondrocyte apoptosis increases with age in the articular cartilage of adult animals
-
Adams CS, Horton WE Jr. Chondrocyte apoptosis increases with age in the articular cartilage of adult animals. Anat Rec 1998;250(4):418-425.
-
(1998)
Anat Rec
, vol.250
, Issue.4
, pp. 418-425
-
-
Adams, C.S.1
Horton Jr., W.E.2
-
82
-
-
3843081686
-
Age-related expression patterns of Bag-1 and Bc1-2 in growth plate and articular chondrocytes
-
Kinkel MD, Yagi R, McBurney D, Nugent A, Horton WE Jr. Age-related expression patterns of Bag-1 and Bc1-2 in growth plate and articular chondrocytes. Anat Rec A Discov Mol Cell Evol Biol 2004;279(2):720-728.
-
(2004)
Anat Rec A Discov Mol Cell Evol Biol
, vol.279
, Issue.2
, pp. 720-728
-
-
Kinkel, M.D.1
Yagi, R.2
McBurney, D.3
Nugent, A.4
Horton Jr., W.E.5
-
83
-
-
4344604554
-
Aging theories of primary osteoarthritis: From epidemiology to molecular biology
-
Aigner T, Rose J, Martin J, Buckwalter J. Aging theories of primary osteoarthritis: from epidemiology to molecular biology. Rejuvenation Res 2004;7(2):134-145.
-
(2004)
Rejuvenation Res
, vol.7
, Issue.2
, pp. 134-145
-
-
Aigner, T.1
Rose, J.2
Martin, J.3
Buckwalter, J.4
-
84
-
-
0037174675
-
Reversal of bone loss in mice by nongenotropic signaling of sex steroids
-
Kousteni S, Chen JR, Bellido T, Han L, Ali AA, O'Brien CA, et al. Reversal of bone loss in mice by nongenotropic signaling of sex steroids. Science 2002;298(5594):843-846.
-
(2002)
Science
, vol.298
, Issue.5594
, pp. 843-846
-
-
Kousteni, S.1
Chen, J.R.2
Bellido, T.3
Han, L.4
Ali, A.A.5
O'Brien, C.A.6
-
85
-
-
0028219108
-
The chemical morphology of age-related changes in human intervertebral disc glycosaminoglycans from cervical, thoracic and lumbar nucleus pulposus and annulus fibrosus
-
Scott JE, Bosworth TR, Cribb AM, Taylor JR. The chemical morphology of age-related changes in human intervertebral disc glycosaminoglycans from cervical, thoracic and lumbar nucleus pulposus and annulus fibrosus. J Anat 1994;184(1):73-82.
-
(1994)
J Anat
, vol.184
, Issue.1
, pp. 73-82
-
-
Scott, J.E.1
Bosworth, T.R.2
Cribb, A.M.3
Taylor, J.R.4
-
86
-
-
3242735151
-
The role of bone in the treatment of osteoarthritis
-
Lajeunesse D. The role of bone in the treatment of osteoarthritis. Osteoarthr Cartilage 2004;12(suppl A):S34-38.
-
(2004)
Osteoarthr Cartilage
, vol.12
, Issue.SUPPL. A
-
-
Lajeunesse, D.1
-
87
-
-
0030307278
-
Microvascular luminal volume changes in aged mouse periodontal ligament
-
Sims MR, Leppard PI, Sampson WJ, Dreyer CW. Microvascular luminal volume changes in aged mouse periodontal ligament. J Dent Res 1996;75(7):1503-1511.
-
(1996)
J Dent Res
, vol.75
, Issue.7
, pp. 1503-1511
-
-
Sims, M.R.1
Leppard, P.I.2
Sampson, W.J.3
Dreyer, C.W.4
-
88
-
-
33645802022
-
Ageing induced adaptations of microvascular reactivity
-
Muller-Delp JM. Ageing induced adaptations of microvascular reactivity. Microcirculation 2006;13(4):301-314.
-
(2006)
Microcirculation
, vol.13
, Issue.4
, pp. 301-314
-
-
Muller-Delp, J.M.1
|