Different sites of xenoantigen delivery lead to a virally induced late-onset hepatitis in mice through molecular mimicry

Liver International

Volumn 31, Issue 9, 2011, Pages 1306-1314

  Piché, Chantal ^a   Béland, Kathie ^a   Lapierre, Pascal ^a   Massie, Bernard ^b,c   Alvarez, Fernando ^a,c  

^a UNIVERSITY OF MONTREAL   (Canada)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Autoimmune hepatitis; Break of immune tolerance; Liver immunology

Indexed keywords

ADENOVIRUS VECTOR; ADENOVIRUS VECTOR CYTOTOXIC T LYMPHOCYTE ANTIGEN 4 CYTOCHROME P45 2D6 FORMIMINOTRANSFERASE CYCLODEAMINASE; ANTIGEN; CYTOCHROME P450 2D6; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DEAMINASE; EPITOPE; FORMIMINOTRANSFERASE CYCLODEAMINASE; HETEROANTIGEN; IMMUNOGLOBULIN; LIVER ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; AUTOIMMUNE HEPATITIS; B LYMPHOCYTE; CONTROLLED STUDY; DNA IMMUNIZATION; EXPRESSION VECTOR; FEMALE; HISTOPATHOLOGY; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOLOGICAL TOLERANCE; LIVER INJURY; MOLECULAR MIMICRY; MOUSE; NONHUMAN; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; AMMONIA-LYASES; ANIMALS; ANTIGENS, HETEROPHILE; B-LYMPHOCYTES; CTLA-4 ANTIGEN; CYTOCHROME P-450 CYP2D6; FEMALE; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GLUTAMATE FORMIMIDOYLTRANSFERASE; HEPATITIS, AUTOIMMUNE; HUMANS; INJECTIONS, INTRAMUSCULAR; INJECTIONS, INTRAVENOUS; LIVER; MICE; MICE, INBRED C57BL; MOLECULAR MIMICRY; TH1 CELLS; TH2 CELLS; TIME FACTORS;

EID: 80052518384     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2011.02600.x     Document Type: Article

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