Induction of G2/M phase arrest and apoptosis by potent antitumor APCA in human cervix carcinoma cells

Anti-Cancer Drugs

Volumn 22, Issue 9, 2011, Pages 875-885

  Xu, Ke ^a   Liang, Xin ^a   Wang, Fang ^a   Xie, Lijuan ^a   Xu, Yufang ^a   Liu, Jianwen ^a   Qian, Xuhong ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

antitumor; apoptosis; cell cycle arrest; G2 M phase; HeLa human cervix carcinoma cells

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 3 (DIMETHYLAMINO ETHYLAMINO) 8 OXO 8H ACENAPHTHOL[1, 2 B]PYRROLE 9 CARBOXYLIC ACID; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 9; CYCLIN DEPENDENT KINASE 1; CYCLINE; CYCLINEB1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; UNCLASSIFIED DRUG; 3 (DIMETHYLAMINO ETHYLAMINO) 8 OXO 8H ACENAPHTHOL(1,2 B)PYRROLE 9 CARBOXYLIC ACID; 3-(DIMETHYLAMINO-ETHYLAMINO)-8-OXO-8H-ACENAPHTHOL(1,2-B)PYRROLE-9-CARBOXYLIC ACID; ACENAPHTHENE DERIVATIVE; CYCLIN B; PYRROLE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; COLONY FORMING CELL; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; GENE TRANSLOCATION; HELA CELL; HUMAN; HUMAN CELL; MORPHOLOGY; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; UTERINE CERVIX CARCINOMA; CELL CYCLE; CELL CYCLE CHECKPOINT; CELL CYCLE G2 PHASE; CELL DIVISION; DRUG EFFECT; FEMALE; METABOLISM; PATHOLOGY; UTERINE CERVIX TUMOR;

ACENAPHTHENES; ANTINEOPLASTIC AGENTS; APOPTOSIS; CDC2 PROTEIN KINASE; CELL CYCLE; CELL CYCLE CHECKPOINTS; CELL DIVISION; CYCLIN B; DOWN-REGULATION; FEMALE; G2 PHASE; HELA CELLS; HUMANS; PYRROLES; UTERINE CERVICAL NEOPLASMS;

EID: 80052503392     PISSN: 09594973     EISSN: 14735741     Source Type: Journal    
DOI: 10.1097/CAD.0b013e328349597d     Document Type: Article

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