The microtubule depolymerizing agent naphthazarin induces both apoptosis and autophagy in A549 lung cancer cells

Apoptosis

Volumn 16, Issue 9, 2011, Pages 924-939

  Acharya, Bipul R ^a,b   Bhattacharyya, Surela ^a   Choudhury, Diptiman ^a   Chakrabarti, Gopal ^a  

^a UNIVERSITY OF CALCUTTA   (India)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Apoptosis; Autophagy; Caspase; Microtubule; Naphthazarin; PI3K Akt

Indexed keywords

CASPASE 3; NAPHTHAZARIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN P53;

APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DEATH; CELL FREE SYSTEM; CELL SURVIVAL; CELL VIABILITY; CYTOTOXICITY; DOSE RESPONSE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IC 50; LUNG NON SMALL CELL CANCER; MICROTUBULE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

APOPTOSIS; AUTOPHAGY; BCL-2-ASSOCIATED X PROTEIN; CARCINOMA, NON-SMALL-CELL LUNG; CASPASE 3; CELL CYCLE; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL SURVIVAL; CELL-FREE SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; HUMANS; IMMUNOPRECIPITATION; INHIBITORY CONCENTRATION 50; MICROSCOPY, CONFOCAL; MICROTUBULES; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MITOTIC INDEX; MOLECULAR STRUCTURE; NAPHTHOQUINONES; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TUBULIN; TUMOR SUPPRESSOR PROTEIN P53;

EID: 80052485674     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-011-0613-1     Document Type: Article

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