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Volumn 55, Issue 6, 2011, Pages 1391-1399

DSS induced colitis increases portal LPS levels and enhances hepatic inflammation and fibrogenesis in experimental NASH

Author keywords

Colitis; Hepatic stellate cell; Intestinal defensin; Liver fibrosis; LPS; NASH; TLR

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; CRAMP PROTEIN; DOCUSATE SODIUM; INTERLEUKIN 17; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PAI 1 PROTEIN; PROTEIN; PROTEIN P47; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 80052477222     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2011.02.035     Document Type: Article
Times cited : (269)

References (39)
  • 1
    • 0033797838 scopus 로고    scopus 로고
    • Prevalence of obesity and diabetes in patients with cryptogenic cirrhosis: A case-control study
    • A. Poonawala, S.P. Nair, and P.J. Thuluvath Prevalence of obesity and diabetes in patients with cryptogenic cirrhosis: a case-control study Hepatology 32 2000 689 692
    • (2000) Hepatology , vol.32 , pp. 689-692
    • Poonawala, A.1    Nair, S.P.2    Thuluvath, P.J.3
  • 2
    • 0036116213 scopus 로고    scopus 로고
    • Non-alcoholic steatohepatitis (NASH): Where are we now and where are we going?
    • C.P. Day Non-alcoholic steatohepatitis (NASH): where are we now and where are we going? Gut 50 2002 585 588
    • (2002) Gut , vol.50 , pp. 585-588
    • Day, C.P.1
  • 3
    • 33644547706 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: From steatosis to cirrhosis
    • G.C. Farrell, and C.Z. Larter Nonalcoholic fatty liver disease: from steatosis to cirrhosis Hepatology 43 2006 S99 S112
    • (2006) Hepatology , vol.43
    • Farrell, G.C.1    Larter, C.Z.2
  • 4
    • 0034831067 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis
    • A.E. Reid Nonalcoholic steatohepatitis Gastroenterology 121 2001 710 723
    • (2001) Gastroenterology , vol.121 , pp. 710-723
    • Reid, A.E.1
  • 6
    • 12344332455 scopus 로고    scopus 로고
    • Cytokines and the pathogenesis of non-alcoholic steatohepatitis
    • A.M. Diehl, Z.P. Li, H.Z. Lin, and S.Q. Yang Cytokines and the pathogenesis of non-alcoholic steatohepatitis Gut 54 2005 303 306
    • (2005) Gut , vol.54 , pp. 303-306
    • Diehl, A.M.1    Li, Z.P.2    Lin, H.Z.3    Yang, S.Q.4
  • 7
    • 33750584214 scopus 로고    scopus 로고
    • TLR4 links innate immunity and fatty acid-induced insulin resistance
    • H. Shi, M.V. Kokoeva, K. Inouye, I. Tzameli, H. Yin, and J.S. Flier TLR4 links innate immunity and fatty acid-induced insulin resistance J Clin Invest 116 2006 3015 3025
    • (2006) J Clin Invest , vol.116 , pp. 3015-3025
    • Shi, H.1    Kokoeva, M.V.2    Inouye, K.3    Tzameli, I.4    Yin, H.5    Flier, J.S.6
  • 8
    • 0141844653 scopus 로고    scopus 로고
    • Reciprocal modulation of Toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids
    • J.Y. Lee, J. Ye, Z. Gao, H.S. Youn, W.H. Lee, and L. Zhao Reciprocal modulation of Toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids J Biol Chem 278 2003 37041 37051
    • (2003) J Biol Chem , vol.278 , pp. 37041-37051
    • Lee, J.Y.1    Ye, J.2    Gao, Z.3    Youn, H.S.4    Lee, W.H.5    Zhao, L.6
  • 9
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: Critical proteins linking innate and acquired immunity
    • S. Akira, K. Takeda, and T. Kaisho Toll-like receptors: critical proteins linking innate and acquired immunity Nat Immunol 2 2001 675 680
    • (2001) Nat Immunol , vol.2 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 10
    • 0035125052 scopus 로고    scopus 로고
    • The role of small intestinal bacterial overgrowth, intestinal permeability, endotox-aemia, and tumour necrosis factor alpha in the pathogenesis of non-alcoholic steatohepatitis
    • A.J. Wigg, I.C. Roberts-Thomson, R.B. Dymock, P.J. McCarthy, R.H. Grose, and A.G. Cummins The role of small intestinal bacterial overgrowth, intestinal permeability, endotox-aemia, and tumour necrosis factor alpha in the pathogenesis of non-alcoholic steatohepatitis Gut 48 2001 206 211
    • (2001) Gut , vol.48 , pp. 206-211
    • Wigg, A.J.1    Roberts-Thomson, I.C.2    Dymock, R.B.3    McCarthy, P.J.4    Grose, R.H.5    Cummins, A.G.6
  • 12
    • 0028796860 scopus 로고
    • Antibiotics prevent liver injury in rats following long-term exposure to ethanol
    • Y. Adachi, L.E. Moore, B.U. Bradford, W. Gao, and R.G. Thurman Antibiotics prevent liver injury in rats following long-term exposure to ethanol Gastroenterology 108 1995 218 224
    • (1995) Gastroenterology , vol.108 , pp. 218-224
    • Adachi, Y.1    Moore, L.E.2    Bradford, B.U.3    Gao, W.4    Thurman, R.G.5
  • 13
    • 0032185432 scopus 로고    scopus 로고
    • II. Alcoholic liver injury involves activation of Kupffer cells by endotoxin
    • R.G. Thurman II. Alcoholic liver injury involves activation of Kupffer cells by endotoxin Am J Physiol 275 1998 G605 G611
    • (1998) Am J Physiol , vol.275
    • Thurman, R.G.1
  • 15
    • 34548272744 scopus 로고    scopus 로고
    • Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis
    • C.A. Rivera, P. Adegboyega, N. van Rooijen, A. Tagalicud, M. Allman, and M. Wallace Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis J Hepatol 47 2007 571 579
    • (2007) J Hepatol , vol.47 , pp. 571-579
    • Rivera, C.A.1    Adegboyega, P.2    Van Rooijen, N.3    Tagalicud, A.4    Allman, M.5    Wallace, M.6
  • 18
    • 68949148889 scopus 로고    scopus 로고
    • Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease
    • L. Miele, V. Valenza, G. La Torre, M. Montalto, G. Cammarota, and R. Ricci Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease Hepatology 49 2009 1877 1887
    • (2009) Hepatology , vol.49 , pp. 1877-1887
    • Miele, L.1    Valenza, V.2    La Torre, G.3    Montalto, M.4    Cammarota, G.5    Ricci, R.6
  • 19
    • 24144461193 scopus 로고    scopus 로고
    • CpG motifs of bacterial DNA essentially contribute to the perpetuation of chronic intestinal inflammation
    • F. Obermeier, N. Dunger, U.G. Strauch, C. Hofmann, A. Bleich, and N. Grunwald CpG motifs of bacterial DNA essentially contribute to the perpetuation of chronic intestinal inflammation Gastroenterology 129 2005 913 927
    • (2005) Gastroenterology , vol.129 , pp. 913-927
    • Obermeier, F.1    Dunger, N.2    Strauch, U.G.3    Hofmann, C.4    Bleich, A.5    Grunwald, N.6
  • 20
    • 1842536819 scopus 로고    scopus 로고
    • Endotoxin-mediated disturbance of hepatic cytochrome P450 function and development of endotoxin tolerance in the rat model of dextran sulfate sodium-induced experimental colitis
    • Y. Masubuchi, and T. Horie Endotoxin-mediated disturbance of hepatic cytochrome P450 function and development of endotoxin tolerance in the rat model of dextran sulfate sodium-induced experimental colitis Drug Metab Dispos 32 2004 437 441
    • (2004) Drug Metab Dispos , vol.32 , pp. 437-441
    • Masubuchi, Y.1    Horie, T.2
  • 21
    • 36348935003 scopus 로고    scopus 로고
    • Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet
    • N. Matsuzawa, T. Takamura, S. Kurita, H. Misu, T. Ota, and H. Ando Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet Hepatology 46 2007 1392 1403
    • (2007) Hepatology , vol.46 , pp. 1392-1403
    • Matsuzawa, N.1    Takamura, T.2    Kurita, S.3    Misu, H.4    Ota, T.5    Ando, H.6
  • 22
    • 0036316394 scopus 로고    scopus 로고
    • CpG motifs of bacterial DNA exacerbate colitis of dextran sulfate sodium-treated mice
    • F. Obermeier, N. Dunger, L. Deml, H. Herfarth, J. Scholmerich, and W. Falk CpG motifs of bacterial DNA exacerbate colitis of dextran sulfate sodium-treated mice Eur J Immunol 32 2002 2084 2092
    • (2002) Eur J Immunol , vol.32 , pp. 2084-2092
    • Obermeier, F.1    Dunger, N.2    Deml, L.3    Herfarth, H.4    Scholmerich, J.5    Falk, W.6
  • 23
    • 59849127774 scopus 로고    scopus 로고
    • CpG motifs of bacterial DNA exert protective effects in mouse models of IBD by antigen-independent tolerance induction
    • A. Bleich, L.M. Janus, A. Smoczek, A.M. Westendorf, U. Strauch, and M. Mahler CpG motifs of bacterial DNA exert protective effects in mouse models of IBD by antigen-independent tolerance induction Gastroenterology 136 2009 278 287
    • (2009) Gastroenterology , vol.136 , pp. 278-287
    • Bleich, A.1    Janus, L.M.2    Smoczek, A.3    Westendorf, A.M.4    Strauch, U.5    Mahler, M.6
  • 26
    • 20044374023 scopus 로고    scopus 로고
    • Design and validation of a histological scoring system for nonalcoholic fatty liver disease
    • D.E. Kleiner, E.M. Brunt, M. Van Natta, C. Behling, M.J. Contos, and O.W. Cummings Design and validation of a histological scoring system for nonalcoholic fatty liver disease Hepatology 41 2005 1313 1321
    • (2005) Hepatology , vol.41 , pp. 1313-1321
    • Kleiner, D.E.1    Brunt, E.M.2    Van Natta, M.3    Behling, C.4    Contos, M.J.5    Cummings, O.W.6
  • 27
    • 67449094451 scopus 로고    scopus 로고
    • Activated hepatic stellate cells promote tumorigenicity of hepatocellular carcinoma
    • T. Amann, F. Bataille, T. Spruss, M. Muhlbauer, E. Gäbele, and J. Scholmerich Activated hepatic stellate cells promote tumorigenicity of hepatocellular carcinoma Cancer Sci 100 2009 646 653
    • (2009) Cancer Sci , vol.100 , pp. 646-653
    • Amann, T.1    Bataille, F.2    Spruss, T.3    Muhlbauer, M.4    Gäbele, E.5    Scholmerich, J.6
  • 29
    • 33645233283 scopus 로고    scopus 로고
    • Rodent nutritional model of steatohepatitis: Effects of endotoxin (lipopolysaccharide) and tumor necrosis factor alpha deficiency
    • R. Kirsch, V. Clarkson, R.C. Verdonk, A.D. Marais, E.G. Shephard, and B. Ryffel Rodent nutritional model of steatohepatitis: effects of endotoxin (lipopolysaccharide) and tumor necrosis factor alpha deficiency J Gastroenterol Hepatol 21 2006 174 182
    • (2006) J Gastroenterol Hepatol , vol.21 , pp. 174-182
    • Kirsch, R.1    Clarkson, V.2    Verdonk, R.C.3    Marais, A.D.4    Shephard, E.G.5    Ryffel, B.6
  • 30
    • 38449120093 scopus 로고    scopus 로고
    • Lipopolysaccharide-binding protein plasma levels and liver TNF-alpha gene expression in obese patients: Evidence for the potential role of endotoxin in the pathogenesis of non-alcoholic steatohepatitis
    • A.G. Ruiz, F. Casafont, J. Crespo, A. Cayon, M. Mayorga, and A. Estebanez Lipopolysaccharide-binding protein plasma levels and liver TNF-alpha gene expression in obese patients: evidence for the potential role of endotoxin in the pathogenesis of non-alcoholic steatohepatitis Obes Surg 17 2007 1374 1380
    • (2007) Obes Surg , vol.17 , pp. 1374-1380
    • Ruiz, A.G.1    Casafont, F.2    Crespo, J.3    Cayon, A.4    Mayorga, M.5    Estebanez, A.6
  • 32
    • 0025181580 scopus 로고
    • A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice
    • I. Okayasu, S. Hatakeyama, M. Yamada, T. Ohkusa, Y. Inagaki, and R. Nakaya A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice Gastroenterology 98 1990 694 702
    • (1990) Gastroenterology , vol.98 , pp. 694-702
    • Okayasu, I.1    Hatakeyama, S.2    Yamada, M.3    Ohkusa, T.4    Inagaki, Y.5    Nakaya, R.6
  • 33
    • 70450064812 scopus 로고    scopus 로고
    • Mucosal immunity: Induction, dissemination, and effector functions
    • P. Brandtzaeg Mucosal immunity: induction, dissemination, and effector functions Scand J Immunol 70 2009 505 515
    • (2009) Scand J Immunol , vol.70 , pp. 505-515
    • Brandtzaeg, P.1
  • 34
    • 74549167737 scopus 로고    scopus 로고
    • Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression
    • E.J. Park, J.H. Lee, G.Y. Yu, G. He, S.R. Ali, and R.G. Holzer Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression Cell 140 2010 197 208
    • (2010) Cell , vol.140 , pp. 197-208
    • Park, E.J.1    Lee, J.H.2    Yu, G.Y.3    He, G.4    Ali, S.R.5    Holzer, R.G.6
  • 36
    • 33745122487 scopus 로고    scopus 로고
    • Improved outcome in shigellosis associated with butyrate induction of an endogenous peptide antibiotic
    • R. Raqib, P. Sarker, P. Bergman, G. Ara, M. Lindh, and D.A. Sack Improved outcome in shigellosis associated with butyrate induction of an endogenous peptide antibiotic Proc Natl Acad Sci USA 103 2006 9178 9183
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 9178-9183
    • Raqib, R.1    Sarker, P.2    Bergman, P.3    Ara, G.4    Lindh, M.5    Sack, D.A.6
  • 37
    • 0035991444 scopus 로고    scopus 로고
    • In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver diseases
    • S. Seki, T. Kitada, T. Yamada, H. Sakaguchi, K. Nakatani, and K. Wakasa In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver diseases J Hepatol 37 2002 56 62
    • (2002) J Hepatol , vol.37 , pp. 56-62
    • Seki, S.1    Kitada, T.2    Yamada, T.3    Sakaguchi, H.4    Nakatani, K.5    Wakasa, K.6
  • 38
    • 0035196704 scopus 로고    scopus 로고
    • Nonalcoholic steatosis and steatohepatitis. II. Cytochrome P-450 enzymes and oxidative stress
    • G. Robertson, I. Leclercq, and G.C. Farrell Nonalcoholic steatosis and steatohepatitis. II. Cytochrome P-450 enzymes and oxidative stress Am J Physiol Gastrointest Liver Physiol 281 2001 G1135 G1139
    • (2001) Am J Physiol Gastrointest Liver Physiol , vol.281
    • Robertson, G.1    Leclercq, I.2    Farrell, G.C.3
  • 39
    • 0018873524 scopus 로고
    • Active oxygen species and the functions of phagocytic leukocytes
    • J.A. Badwey, and M.L. Karnovsky Active oxygen species and the functions of phagocytic leukocytes Annu Rev Biochem 49 1980 695 726
    • (1980) Annu Rev Biochem , vol.49 , pp. 695-726
    • Badwey, J.A.1    Karnovsky, M.L.2


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