Impaired neutrophil actin assembly causes persistent CD11b expression and reduced primary granule exocytosis in Type II diabetes

Diabetologia

Volumn 45, Issue 5, 2002, Pages 719-727

  Advani, A ^a   Marshall, S M ^a   Thomas, T H ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Cardiovascular disease; CD11b CD18; Cytoskeleton; Neutrophil; Type II diabetes

Indexed keywords

ANAZOLENE SODIUM; BETA2 INTEGRIN; CD11B ANTIGEN; CD69 ANTIGEN; CELL MARKER; CYTOCHALASIN D; F ACTIN; FLUORESCEIN ISOTHIOCYANATE; FORMYLMETHIONYLLEUCYLPHENYLALANINE; OCTOXINOL; PHALLOIDIN; PHORBOL 12 ACETATE 13 MYRISTATE; ACTIN; CD18 ANTIGEN; LEUKOCYTE ANTIGEN; PHORBOL 13 ACETATE 12 MYRISTATE; T LYMPHOCYTE ANTIGEN;

ACTIN POLYMERIZATION; ADULT; ANTIGEN EXPRESSION; ARTICLE; CARDIOVASCULAR RISK; CELL ACTIVATION; CELL FRACTIONATION; CELL LOSS; CELL SURFACE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE MARKER; EXOCYTOSIS; FLOW CYTOMETRY; FLUORESCENCE; HUMAN; HUMAN CELL; NEUTROPHIL; NON INSULIN DEPENDENT DIABETES MELLITUS; OPTICAL DENSITY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ASSEMBLY; STAINING; BLOOD; CELL GRANULE; CYTOSKELETON; DRUG EFFECT; LEUKOCYTE ACTIVATION; MIDDLE AGED; PHYSIOLOGY; ULTRASTRUCTURE;

ACTINS; ANTIGENS, CD; ANTIGENS, CD11B; ANTIGENS, CD18; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CYTOPLASMIC GRANULES; CYTOSKELETON; DIABETES MELLITUS, NON-INSULIN-DEPENDENT; EXOCYTOSIS; HUMAN; MIDDLE AGE; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHIL ACTIVATION; NEUTROPHILS; SUPPORT, NON-U.S. GOV'T; TETRADECANOYLPHORBOL ACETATE; DIABETES MELLITUS, TYPE 2; HUMANS; MIDDLE AGED;

EID: 0035985095     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-002-0802-0     Document Type: Article

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