SCOPUS 정보 검색 플랫폼

Tetrahedron

Volumn 67, Issue 40, 2011, Pages 7805-7810

Synthesis of a novel pyrrolo[1,2-c][1.3]benzodiazepine analogue of VPA-985

(3) Rotas, Georgios a Kimbaris, Athanasios a Varvounis, George a

a UNIVERSITY OF IOANNINA (Greece)

Author keywords

Cyclisation; Desulfurisation; Pyrrole; Pyrrolobenzodiazepine; Reduction

Indexed keywords

(2 AMINOPHENYL)(1H PYRROL 2 YL)METHANONE; (2 ISOTHIOCYANATOPHENYL)(1H PYRROL 2 YL)METHANONE; 2 CHLORO 4 NITROBENZOYL CHLORIDE; 5 THIOXO 5,6 DIHYDRO 11H PYRROLO[1,2 C][1.3]BENZODIAZEPIN 11 ONE; 6 (2 CHLORO 4 NITROBENZOYL) 6,11 DIHYDRO 5H PYRROLO[1,2 C][1.3]BENZODIAZEPINE; 6,11 DIHYDRO 5H PYRROLO[1,2 C][1.3]BENZODIAZEPINE 5 THIONE; ALUMINUM DERIVATIVE; ALUMINUM LITHIUM HYDRIDE; ALUMINUM TRICHLORIDE; AMMONIUM CHLORIDE; BENZODIAZEPINE DERIVATIVE; LIXIVAPTAN; N [3 CHLORO 4 (5H PYRROLO[1,2 C][1.3]BENZODIAZEPIN 6 (11H) YLCARBONYL)PHENYL] 5 FLUORO 2 METHYLBENZAMIDE; UNCLASSIFIED DRUG; ZINC;

ACYLATION; ARTICLE; CYCLIZATION; DESULFURIZATION; DRUG SYNTHESIS; PRIORITY JOURNAL; REDUCTION;

EID: 80052405637 PISSN: 00404020 EISSN: 14645416 Source Type: Journal
DOI: 10.1016/j.tet.2011.07.083 Document Type: Article

Times cited : (19)

References (31)

1
- 0013852032
- W. Leimgruber, V. Stefanovic, F. Schenker, A. Karr, and J. Berger J. Am. Chem. Soc. 87 1965 5791
- (1965) J. Am. Chem. Soc. , vol.87 , pp. 5791
- Leimgruber, W.¹ Stefanovic, V.² Schenker, F.³ Karr, A.⁴ Berger, J.⁵

2
- 0013851934
- W. Leimgruber, A.D. Batcho, and F. Schenker J. Am. Chem. Soc. 87 1965 5793
- (1965) J. Am. Chem. Soc. , vol.87 , pp. 5793
- Leimgruber, W.¹ Batcho, A.D.² Schenker, F.³

3
- 0000143411
- D.E. Thurston, and D.S. Bose Chem. Rev. 94 1994 433
- (1994) Chem. Rev. , vol.94 , pp. 433
- Thurston, D.E.¹ Bose, D.S.²

4
- 0002070325
- The Macmillan London, UK
- D.E. Thurston S. Neidle, M.J. Waring, Molecular Aspects of Anticancer Drug-DNA Interactions Vol. 1 1993 The Macmillan London, UK 54
- (1993) Molecular Aspects of Anticancer Drug-DNA Interactions , vol.1 , pp. 54
- Thurston, D.E.¹ Neidle, S.² Waring, M.J.³

5
- 33947176724
- A. Antonow, T.C. Jenkins, P.W. Howard, and D.E. Thurston Bioorg. Med. Chem. 15 2007 3041
- (2007) Bioorg. Med. Chem. , vol.15 , pp. 3041
- Antonow, A.¹ Jenkins, T.C.² Howard, P.W.³ Thurston, D.E.⁴

6
- 77950584653
- D. Antonow, M. Kaliszczak, G.-D. Kang, M.J. Coffils, A.C. Tiberghien, N. Cooper, T. Barata, S. Heidelberger, C.H. James, M. Zloh, T.C. Jenkins, A.P. Reszka, S. Neidle, S.M. Guichard, D.I. Jodrell, J.A. Hartley, P.W. Howard, and D.E. Thurston J. Med. Chem. 53 2010 2927
- (2010) J. Med. Chem. , vol.53 , pp. 2927
- Antonow, D.¹ Kaliszczak, M.² Kang, G.-D.³ Coffils, M.J.⁴ Tiberghien, A.C.⁵ Cooper, N.⁶ Barata, T.⁷ Heidelberger, S.⁸ James, C.H.⁹ Zloh, M.¹⁰ Jenkins, T.C.¹¹ Reszka, A.P.¹² Neidle, S.¹³ Guichard, S.M.¹⁴ Jodrell, D.I.¹⁵ Hartley, J.A.¹⁶ Howard, P.W.¹⁷ Thurston, D.E.¹⁸

7
- 77955656508
- A. Kamal, J.S. Reddy, M.J. Ramaiah, E.V. Bharathi, D. Dastagiri, M.K. Reddy, S.N.C.V.L. Pushpavalli, and M. Pal-Bhadra Bioorg. Med. Chem. Lett. 20 2010 5232
- (2010) Bioorg. Med. Chem. Lett. , vol.20 , pp. 5232
- Kamal, A.¹ Reddy, J.S.² Ramaiah, M.J.³ Bharathi, E.V.⁴ Dastagiri, D.⁵ Reddy, M.K.⁶ Pushpavalli, S.N.C.V.L.⁷ Pal-Bhadra, M.⁸

8
- 77955559364
- A. Kamal, J.S. Reddy, M.J. Ramaiah, D. Dastagiri, E.V. Bharathi, M.A. Azhar, F. Sultana, S.N.C.V.L. Pushpavalli, M. Pal-Bhadra, A. Juvekar, S. Sen, and S. Zingde Eur. J. Med. Chem. 45 2010 3924
- (2010) Eur. J. Med. Chem. , vol.45 , pp. 3924
- Kamal, A.¹ Reddy, J.S.² Ramaiah, M.J.³ Dastagiri, D.⁴ Bharathi, E.V.⁵ Azhar, M.A.⁶ Sultana, F.⁷ Pushpavalli, S.N.C.V.L.⁸ Pal-Bhadra, M.⁹ Juvekar, A.¹⁰ Sen, S.¹¹ Zingde, S.¹²

9
- 61749097371
- L. Cipolla, A.C. Araújo, C. Airoldi, and D. Bini Anti-Cancer Agents Med. Chem. 9 2009 1
- (2009) Anti-Cancer Agents Med. Chem. , vol.9 , pp. 1
- Cipolla, L.¹ Araújo, A.C.² Airoldi, C.³ Bini, D.⁴

10
- 71049132318
- P.W. Howard, Z. Chen, S.J. Gregson, L.A. Masterson, A.C. Tiberghien, N. Cooper, M. Fang, M.J. Coffils, S. Klee, J.A. Hartley, and D.E. Thurston Bioorg. Med. Chem. Lett. 19 2009 6463
- (2009) Bioorg. Med. Chem. Lett. , vol.19 , pp. 6463
- Howard, P.W.¹ Chen, Z.² Gregson, S.J.³ Masterson, L.A.⁴ Tiberghien, A.C.⁵ Cooper, N.⁶ Fang, M.⁷ Coffils, M.J.⁸ Klee, S.⁹ Hartley, J.A.¹⁰ Thurston, D.E.¹¹

11
- 77954315033
- A. Kamal, N. Shankaraiah, C.R. Reddy, S. Prabhakar, N. Markandeya, H.K. Srivastava, and G.N. Sastry Tetrahedron 66 2010 5498
- (2010) Tetrahedron , vol.66 , pp. 5498
- Kamal, A.¹ Shankaraiah, N.² Reddy, C.R.³ Prabhakar, S.⁴ Markandeya, N.⁵ Srivastava, H.K.⁶ Sastry, G.N.⁷

12
- 14444285742
- J.D. Albright, M.F. Reich, E.G. Delos Santos, J.P. Dusza, F. Sum, A.M. Venkatesan, J. Coupet, P.S. Chan, X. Ru, H. Mazandarani, and T. Bailey J. Med. Chem. 41 1998 2442
- (1998) J. Med. Chem. , vol.41 , pp. 2442
- Albright, J.D.¹ Reich, M.F.² Delos Santos, E.G.³ Dusza, J.P.⁴ Sum, F.⁵ Venkatesan, A.M.⁶ Coupet, J.⁷ Chan, P.S.⁸ Ru, X.⁹ Mazandarani, H.¹⁰ Bailey, T.¹¹

13
- 0033526884
- V. Aranapakam, J.D. Albright, G.T. Grosu, E.G. Delos Santos, P.S. Chan, J. Coupet, X. Ru, T. Saunders, and H. Mazandarani Bioorg. Med. Chem. Lett. 9 1999 1737
- (1999) Bioorg. Med. Chem. Lett. , vol.9 , pp. 1737
- Aranapakam, V.¹ Albright, J.D.² Grosu, G.T.³ Delos Santos, E.G.⁴ Chan, P.S.⁵ Coupet, J.⁶ Ru, X.⁷ Saunders, T.⁸ Mazandarani, H.⁹

14
- 0342748371
- J.D. Albright, E.F. Delos Santos, J.P. Dusza, P.S. Chan, J. Coupet, X. Ru, and H. Mazandarani Bioorg. Med. Chem. Lett. 10 2000 695
- (2000) Bioorg. Med. Chem. Lett. , vol.10 , pp. 695
- Albright, J.D.¹ Delos Santos, E.F.² Dusza, J.P.³ Chan, P.S.⁴ Coupet, J.⁵ Ru, X.⁶ Mazandarani, H.⁷

15
- 12444305003
- F.-W. Sum, J. Dusza, E. Delos Santos, G. Grosu, M. Reich, X. Du, J.D. Albright, P. Chan, J. Coupet, X. Ru, H. Mazandarani, and T. Saunders Bioorg. Med. Chem. Lett. 13 2003 2195
- (2003) Bioorg. Med. Chem. Lett. , vol.13 , pp. 2195
- Sum, F.-W.¹ Dusza, J.² Delos Santos, E.³ Grosu, G.⁴ Reich, M.⁵ Du, X.⁶ Albright, J.D.⁷ Chan, P.⁸ Coupet, J.⁹ Ru, X.¹⁰ Mazandarani, H.¹¹ Saunders, T.¹²

16
- 0032811742
- K. Kondo, H. Ogawa, H. Yamashita, H. Miyamoto, M. Tanaka, K. Nakaya, K. Kitano, Y. Yamamura, S. Nakamura, T. Onogawa, T. Mori, and M. Tominago Bioorg. Med. Chem. 7 1999 1743
- (1999) Bioorg. Med. Chem. , vol.7 , pp. 1743
- Kondo, K.¹ Ogawa, H.² Yamashita, H.³ Miyamoto, H.⁴ Tanaka, M.⁵ Nakaya, K.⁶ Kitano, K.⁷ Yamamura, Y.⁸ Nakamura, S.⁹ Onogawa, T.¹⁰ Mori, T.¹¹ Tominago, M.¹²

17
- 0035101454
- J. Matsubara, S. Morita, H. Yamashita, K. Otsubo, K. Kitano, T. Ohtani, Y. Kawano, M. Bando, M. Kido, M. Uchida, and F. Tabusa Heterocycles 54 2001 131
- (2001) Heterocycles , vol.54 , pp. 131
- Matsubara, J.¹ Morita, S.² Yamashita, H.³ Otsubo, K.⁴ Kitano, K.⁵ Ohtani, T.⁶ Kawano, Y.⁷ Bando, M.⁸ Kido, M.⁹ Uchida, M.¹⁰ Tabusa, F.¹¹

18
- 35649007351
- Y. Torisawa, T. Furuta, T. Nishi, S. Akiand, and J. Minamikawa Bioorg. Med. Chem. Lett. 17 2007 6455
- (2007) Bioorg. Med. Chem. Lett. , vol.17 , pp. 6455
- Torisawa, Y.¹ Furuta, T.² Nishi, T.³ Akiand, S.⁴ Minamikawa, J.⁵

19
- 78149282261
- L. Yin, Y. Zheng, X. Jia, X. Li, and A.S.C. Chan Tetrahedron: Asymmetry 21 2010 2390
- (2010) Tetrahedron: Asymmetry , vol.21 , pp. 2390
- Yin, L.¹ Zheng, Y.² Jia, X.³ Li, X.⁴ Chan, A.S.C.⁵

20
- 0035356218
- H. Venkatesan, M.C. Davis, Y. Altas, J.P. Snyder, and D.C. Liotta J. Org. Chem. 66 2001 3653
- (2001) J. Org. Chem. , vol.66 , pp. 3653
- Venkatesan, H.¹ Davis, M.C.² Altas, Y.³ Snyder, J.P.⁴ Liotta, D.C.⁵

21
- 0034777171
- A. Martinez-Castelao Curr. Opin. Invest. Drugs 2 2001 1423
- (2001) Curr. Opin. Invest. Drugs , vol.2 , pp. 1423
- Martinez-Castelao, A.¹

22
- 0037197989
- C. Serradeil-Le Gal, J.-P. Maffrand, and P. Soubrie Proc. Natl. Acad. Sci. U.S.A. 99 2002 6370
- (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 6370
- Serradeil-Le Gal, C.¹ Maffrand, J.-P.² Soubrie, P.³

23
- 0001032924
- H. Masahito, S. Hiroshi, and H. Hiroshi Heterocycles 48 1998 1331
- (1998) Heterocycles , vol.48 , pp. 1331
- Masahito, H.¹ Hiroshi, S.² Hiroshi, H.³

24
- 20444396559
- G. Rotas, K. Natchkebia, N. Natsvlishvili, M. Kekelidze, G. Varvounis, and D. Mikeladze Bioorg. Med. Chem. Lett. 15 2005 3220
- (2005) Bioorg. Med. Chem. Lett. , vol.15 , pp. 3220
- Rotas, G.¹ Natchkebia, K.² Natsvlishvili, N.³ Kekelidze, M.⁴ Varvounis, G.⁵ Mikeladze, D.⁶

25
- 0034551621
- A. Kimbaris, and G. Varvounis Tetrahedron 56 2000 9675
- (2000) Tetrahedron , vol.56 , pp. 9675
- Kimbaris, A.¹ Varvounis, G.²

26
- 5044234791
- C.C. Llopard, and J.A. Joule Arkivoc 10 2004 20
- (2004) Arkivoc , vol.10 , pp. 20
- Llopard, C.C.¹ Joule, J.A.²

27
- 0037067561
- S. Nandi, U.K.S. Kumar, H. Ila, and H. Junjappa J. Org. Chem. 67 2002 4916
- (2002) J. Org. Chem. , vol.67 , pp. 4916
- Nandi, S.¹ Kumar, U.K.S.² Ila, H.³ Junjappa, H.⁴

28
- 0025779182
- P.-P. Kung, and R.A. Jones Tetrahedron Lett. 32 1991 3919
- (1991) Tetrahedron Lett. , vol.32 , pp. 3919
- Kung, P.-P.¹ Jones, R.A.²

29
- 0000562359
- E.C. Kornfeld J. Org. Chem. 16 1951 131
- (1951) J. Org. Chem. , vol.16 , pp. 131
- Kornfeld, E.C.¹

30
- 0029075894
- A. Mai, R. Di Santo, S. Massa, M. Artico, G.C. Pantaleoni, R. Giorgi, M.F. Coppolino, and A. Barracchini Eur. J. Med. Chem. 30 1995 593
- (1995) Eur. J. Med. Chem. , vol.30 , pp. 593
- Mai, A.¹ Di Santo, R.² Massa, S.³ Artico, M.⁴ Pantaleoni, G.C.⁵ Giorgi, R.⁶ Coppolino, M.F.⁷ Barracchini, A.⁸

31
- 0004055425
- Butterworth-Heinemann Oxford
- W.L.F. Armarego, and D.D. Perrin Purification of Laboratory Chemicals 1996 Butterworth-Heinemann Oxford
- (1996) Purification of Laboratory Chemicals
- Armarego, W.L.F.¹ Perrin, D.D.²

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.