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Journal of Organic Chemistry

Volumn 66, Issue 11, 2001, Pages 3653-3661

Total synthesis of SR 121463 A, a highly potent and selective vasopressin V2 receptor antagonist

(5) Venkatesan, H a,b Davis, M C a Altas, Y a Snyder, J P a Liotta, D C a

a EMORY UNIVERSITY (United States)

b R W JOHNSON PHARMACEUTICAL RES I (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MOLECULAR MECHANICS;

CHELATION; ISOMERS; LITHIUM; POSITIVE IONS; STEREOCHEMISTRY; SYNTHESIS (CHEMICAL);

ORGANIC COMPOUNDS;

N TERT BUTYL 4 [5' ETHOXY 4 (2 MORPHOLINOETHOXY) 2' OXOSPIRO[CYCLOHEXANE 1,3' INDOLE] 1' SULFONYL] 3 METHOXYBENZAMIDE; VASOPRESSIN RECEPTOR ANTAGONIST; VASOPRESSIN V2 RECEPTOR;

ARTICLE; CALCULATION; CHEMICAL REACTION; DRUG POTENCY; DRUG SYNTHESIS; HYPONATREMIA; ISOMER; MOLECULAR DYNAMICS; RECEPTOR BLOCKING; STEREOCHEMISTRY;

GAS CHROMATOGRAPHY-MASS SPECTROMETRY; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MORPHOLINES; OXIDATION-REDUCTION; RECEPTORS, VASOPRESSIN; SPIRO COMPOUNDS; STEREOISOMERISM;

EID: 0035356218 PISSN: 00223263 EISSN: None Source Type: Journal
DOI: 10.1021/jo0004658 Document Type: Article

Times cited : (132)

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