The synthesis and vasopressin (AVP) antagonist activity of a novel series of N-Aroyl-2,4,5,6-tetrahydropyrazolo-[3,4-d]thieno[3,2-b]azepines

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 8, 2000, Pages 695-698

  Albright, J Donald ^a   Santos, Efren G Delos ^a   Dusza, John P ^a   Chan, Peter S ^a   Coupet, Joseph ^a   Ru, Xun ^a   Mazandarani, H ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOTHIOPHENE DERIVATIVE; HYDROXYLAMINE; N [4 [(4,5 DIHYDROPYRAZOLO[3,4 D]THIENO[3,2 B]AZEPIN 6(2H) YL)CARBONYL]PHENYL]BENZAMIDE; PYRAZOLE DERIVATIVE; TOLUENESULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG; VASOPRESSIN RECEPTOR ANTAGONIST; VASOPRESSIN V1 RECEPTOR; VASOPRESSIN V2 RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HORMONE INHIBITION; HUMAN; HUMAN EXPERIMENT; IN VITRO STUDY; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION; URINE VOLUME;

ANIMALS; ARGININE VASOPRESSIN; AZEPINES; RATS; RECEPTORS, VASOPRESSIN; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA;

EID: 0342748371     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00084-6     Document Type: Article

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