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Volumn 6, Issue 9, 2011, Pages

Somatostatin receptor 1 and 5 double knockout mice mimic neurochemical changes of Huntington's disease transgenic mice

Author keywords

[No Author keywords available]

Indexed keywords

CALBINDIN; CALCINEURIN; CALPAIN; CYCLIC AMP; DOPAMINE; ENKEPHALIN; MITOGEN ACTIVATED PROTEIN KINASE 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; NITRIC OXIDE SYNTHASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOPROTEIN DARPP 32; PROTEIN KINASE C ALPHA; SOMATOSTATIN RECEPTOR 1; SOMATOSTATIN RECEPTOR 5; SYNAPSIN II; SYNAPSIN IIA; UNCLASSIFIED DRUG; NEURONAL NITRIC OXIDE SYNTHASE; NOS1 PROTEIN, MOUSE; SOMATOSTATIN RECEPTOR; SOMATOSTATIN RECEPTOR TYPE 1;

EID: 80052394262     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024467     Document Type: Article
Times cited : (25)

References (75)
  • 1
    • 0023750525 scopus 로고
    • Morphometric demonstration of atrophic changes in the cerebral cortex, white matter, and neostriatum in Huntington's disease
    • de la Monte SM, Vonsattel JP, Richardson EP Jr, (1988) Morphometric demonstration of atrophic changes in the cerebral cortex, white matter, and neostriatum in Huntington's disease. J Neuropathol Exp Neurol 47: 516-525.
    • (1988) J Neuropathol Exp Neurol , vol.47 , pp. 516-525
    • de la Monte, S.M.1    Vonsattel, J.P.2    Richardson Jr., E.P.3
  • 2
    • 33644956493 scopus 로고    scopus 로고
    • Striatal modulation of cAMP-response-element-binding protein (CREB) after excitotoxic lesions: implications with neuronal vulnerability in Huntington's disease
    • Giampa C, DeMarch Z, D'Angelo V, Morello M, Martorana A, et al. (2006) Striatal modulation of cAMP-response-element-binding protein (CREB) after excitotoxic lesions: implications with neuronal vulnerability in Huntington's disease. Eur J Neurosci 23: 11-20.
    • (2006) Eur J Neurosci , vol.23 , pp. 11-20
    • Giampa, C.1    DeMarch, Z.2    D'Angelo, V.3    Morello, M.4    Martorana, A.5
  • 3
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • The Huntington's Disease Collaborative Research Group
    • The Huntington's Disease Collaborative Research Group (1993) A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 72: 971-983.
    • (1993) Cell , vol.72 , pp. 971-983
  • 4
    • 0030793341 scopus 로고    scopus 로고
    • Expression of NMDA Receptor-1 (NR1) and Huntingtin in Striatal Neurons Which Colocalize Somatostatin, Neuropeptide Y, and NADPH Diaphorase: A Double-Label Histochemical and Immunohistochemical Study
    • Kumar U, Asotra K, Patel SC, Patel YC, (1997) Expression of NMDA Receptor-1 (NR1) and Huntingtin in Striatal Neurons Which Colocalize Somatostatin, Neuropeptide Y, and NADPH Diaphorase: A Double-Label Histochemical and Immunohistochemical Study. Experimental Neurology 145: 412-424.
    • (1997) Experimental Neurology , vol.145 , pp. 412-424
    • Kumar, U.1    Asotra, K.2    Patel, S.C.3    Patel, Y.C.4
  • 5
    • 0030935035 scopus 로고    scopus 로고
    • The likelihood of being affected with Huntington disease by a particular age, for a specific CAG size
    • Brinkman RR, Mezei MM, Theilmann J, Almqvist E, Hayden MR, (1997) The likelihood of being affected with Huntington disease by a particular age, for a specific CAG size. Am J Hum Genet 60: 1202-1210.
    • (1997) Am J Hum Genet , vol.60 , pp. 1202-1210
    • Brinkman, R.R.1    Mezei, M.M.2    Theilmann, J.3    Almqvist, E.4    Hayden, M.R.5
  • 6
    • 0034329159 scopus 로고    scopus 로고
    • Molecular genetics: unmasking polyglutamine triggers in neurodegenerative disease
    • Gusella JF, MacDonald ME, (2000) Molecular genetics: unmasking polyglutamine triggers in neurodegenerative disease. Nat Rev Neurosci 1: 109-115.
    • (2000) Nat Rev Neurosci , vol.1 , pp. 109-115
    • Gusella, J.F.1    MacDonald, M.E.2
  • 7
    • 0029839623 scopus 로고    scopus 로고
    • Striatal interneurons in Huntington's disease: selective increase in the density of calretinin-immunoreactive medium-sized neurons
    • Cicchetti F, Parent A, (1996) Striatal interneurons in Huntington's disease: selective increase in the density of calretinin-immunoreactive medium-sized neurons. Mov Disord 11: 619-626.
    • (1996) Mov Disord , vol.11 , pp. 619-626
    • Cicchetti, F.1    Parent, A.2
  • 9
    • 0028831934 scopus 로고
    • Quinolinic acid-induced increases in calbindin D28k immunoreactivity in rat striatal neurons in vivo and in vitro mimic the pattern seen in Huntington's disease
    • Huang Q, Zhou D, Sapp E, Aizawa H, Ge P, et al. (1995) Quinolinic acid-induced increases in calbindin D28k immunoreactivity in rat striatal neurons in vivo and in vitro mimic the pattern seen in Huntington's disease. Neuroscience 65: 397-407.
    • (1995) Neuroscience , vol.65 , pp. 397-407
    • Huang, Q.1    Zhou, D.2    Sapp, E.3    Aizawa, H.4    Ge, P.5
  • 10
    • 0025196525 scopus 로고
    • Calbindin D28K as a marker for the degeneration of the striatonigral pathway in Huntington's disease
    • Kiyama H, Seto-Ohshima A, Emson PC, (1990) Calbindin D28K as a marker for the degeneration of the striatonigral pathway in Huntington's disease. Brain Res 525: 209-214.
    • (1990) Brain Res , vol.525 , pp. 209-214
    • Kiyama, H.1    Seto-Ohshima, A.2    Emson, P.C.3
  • 11
    • 27744487206 scopus 로고    scopus 로고
    • Increased calbindin-D28k immunoreactivity in striatal projection neurons of R6/2 Huntington's disease transgenic mice
    • Sun Z, Wang HB, Deng YP, Lei WL, Xie JP, et al. (2005) Increased calbindin-D28k immunoreactivity in striatal projection neurons of R6/2 Huntington's disease transgenic mice. Neurobiol Dis 20: 907-917.
    • (2005) Neurobiol Dis , vol.20 , pp. 907-917
    • Sun, Z.1    Wang, H.B.2    Deng, Y.P.3    Lei, W.L.4    Xie, J.P.5
  • 12
    • 1242338856 scopus 로고    scopus 로고
    • Huntingtin-protein interactions and the pathogenesis of Huntington's disease
    • Li SH, Li XJ, (2004) Huntingtin-protein interactions and the pathogenesis of Huntington's disease. Trends Genet 20: 146-154.
    • (2004) Trends Genet , vol.20 , pp. 146-154
    • Li, S.H.1    Li, X.J.2
  • 13
    • 0025322132 scopus 로고
    • Abnormalities of striatal projection neurons and N-methyl-D-aspartate receptors in presymptomatic Huntington's disease
    • Albin RL, Young AB, Penney JB, Handelin B, Balfour R, et al. (1990) Abnormalities of striatal projection neurons and N-methyl-D-aspartate receptors in presymptomatic Huntington's disease. N Engl J Med 322: 1293-1298.
    • (1990) N Engl J Med , vol.322 , pp. 1293-1298
    • Albin, R.L.1    Young, A.B.2    Penney, J.B.3    Handelin, B.4    Balfour, R.5
  • 14
    • 0023690166 scopus 로고
    • NMDA receptor losses in putamen from patients with Huntington's disease
    • Young AB, Greenamyre JT, Hollingsworth Z, Albin R, D'Amato C, et al. (1988) NMDA receptor losses in putamen from patients with Huntington's disease. Science 241: 981-983.
    • (1988) Science , vol.241 , pp. 981-983
    • Young, A.B.1    Greenamyre, J.T.2    Hollingsworth, Z.3    Albin, R.4    D'Amato, C.5
  • 15
    • 0028343648 scopus 로고
    • Developmental and regional expression in the rat brain and functional properties of four NMDA receptors
    • Monyer H, Burnashev N, Laurie DJ, Sakmann B, Seeburg PH, (1994) Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron 12: 529-540.
    • (1994) Neuron , vol.12 , pp. 529-540
    • Monyer, H.1    Burnashev, N.2    Laurie, D.J.3    Sakmann, B.4    Seeburg, P.H.5
  • 16
    • 0031912995 scopus 로고    scopus 로고
    • Glutamate receptors in the mammalian central nervous system
    • Ozawa S, Kamiya H, Tsuzuki K, (1998) Glutamate receptors in the mammalian central nervous system. Prog Neurobiol 54: 581-618.
    • (1998) Prog Neurobiol , vol.54 , pp. 581-618
    • Ozawa, S.1    Kamiya, H.2    Tsuzuki, K.3
  • 17
    • 0032971311 scopus 로고    scopus 로고
    • Subtype-specific enhancement of NMDA receptor currents by mutant huntingtin
    • Chen N, Luo T, Wellington C, Metzler M, McCutcheon K, et al. (1999) Subtype-specific enhancement of NMDA receptor currents by mutant huntingtin. J Neurochem 72: 1890-1898.
    • (1999) J Neurochem , vol.72 , pp. 1890-1898
    • Chen, N.1    Luo, T.2    Wellington, C.3    Metzler, M.4    McCutcheon, K.5
  • 18
    • 34047100940 scopus 로고    scopus 로고
    • N-methyl-D-aspartate (NMDA) receptor function and excitotoxicity in Huntington's disease
    • Fan MM, Raymond LA, (2007) N-methyl-D-aspartate (NMDA) receptor function and excitotoxicity in Huntington's disease. Prog Neurobiol 81: 272-293.
    • (2007) Prog Neurobiol , vol.81 , pp. 272-293
    • Fan, M.M.1    Raymond, L.A.2
  • 19
    • 71549143207 scopus 로고    scopus 로고
    • Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin
    • Okamoto S, Pouladi MA, Talantova M, Yao D, Xia P, et al. (2009) Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin. Nat Med 15: 1407-1413.
    • (2009) Nat Med , vol.15 , pp. 1407-1413
    • Okamoto, S.1    Pouladi, M.A.2    Talantova, M.3    Yao, D.4    Xia, P.5
  • 20
    • 0026043565 scopus 로고
    • Chronic quinolinic acid lesions in rats closely resemble Huntington's disease
    • Beal MF, Ferrante RJ, Swartz KJ, Kowall NW, (1991) Chronic quinolinic acid lesions in rats closely resemble Huntington's disease. J Neurosci 11: 1649-1659.
    • (1991) J Neurosci , vol.11 , pp. 1649-1659
    • Beal, M.F.1    Ferrante, R.J.2    Swartz, K.J.3    Kowall, N.W.4
  • 21
    • 0022446150 scopus 로고
    • Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid
    • Beal MF, Kowall NW, Ellison DW, Mazurek MF, Swartz KJ, et al. (1986) Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid. Nature 321: 168-171.
    • (1986) Nature , vol.321 , pp. 168-171
    • Beal, M.F.1    Kowall, N.W.2    Ellison, D.W.3    Mazurek, M.F.4    Swartz, K.J.5
  • 22
    • 0020600483 scopus 로고
    • Somatostatin is increased in the basal ganglia in Huntington disease
    • Aronin N, Cooper PE, Lorenz LJ, Bird ED, Sagar SM, et al. (1983) Somatostatin is increased in the basal ganglia in Huntington disease. Ann Neurol 13: 519-526.
    • (1983) Ann Neurol , vol.13 , pp. 519-526
    • Aronin, N.1    Cooper, P.E.2    Lorenz, L.J.3    Bird, E.D.4    Sagar, S.M.5
  • 23
    • 0021337138 scopus 로고
    • Somatostatin is increased in the nucleus accumbens in Huntington's disease
    • Beal MF, Bird ED, Langlais PJ, Martin JB, (1984) Somatostatin is increased in the nucleus accumbens in Huntington's disease. Neurology 34: 663-666.
    • (1984) Neurology , vol.34 , pp. 663-666
    • Beal, M.F.1    Bird, E.D.2    Langlais, P.J.3    Martin, J.B.4
  • 24
    • 0022392290 scopus 로고
    • Survival of basal ganglia neuropeptide Y-somatostatin neurones in Huntington's disease
    • Dawbarn D, De Quidt ME, Emson PC, (1985) Survival of basal ganglia neuropeptide Y-somatostatin neurones in Huntington's disease. Brain Res 340: 251-260.
    • (1985) Brain Res , vol.340 , pp. 251-260
    • Dawbarn, D.1    de Quidt, M.E.2    Emson, P.C.3
  • 25
    • 0020519798 scopus 로고
    • Regional brain concentrations of neuropeptides in Huntington's chorea and schizophrenia
    • Nemeroff CB, Youngblood WW, Manberg PJ, Prange AJ Jr, Kizer JS, (1983) Regional brain concentrations of neuropeptides in Huntington's chorea and schizophrenia. Science 221: 972-975.
    • (1983) Science , vol.221 , pp. 972-975
    • Nemeroff, C.B.1    Youngblood, W.W.2    Manberg, P.J.3    Prange Jr., A.J.4    Kizer, J.S.5
  • 26
    • 0020579680 scopus 로고
    • Striatal neurons containing both somatostatin- and avian pancreatic polypeptide (APP)-like immunoreactivities and NADPH-diaphorase activity: a light and electron microscopic study
    • Vincent SR, Johansson O, (1983) Striatal neurons containing both somatostatin- and avian pancreatic polypeptide (APP)-like immunoreactivities and NADPH-diaphorase activity: a light and electron microscopic study. J Comp Neurol 217: 264-270.
    • (1983) J Comp Neurol , vol.217 , pp. 264-270
    • Vincent, S.R.1    Johansson, O.2
  • 27
    • 0026087171 scopus 로고
    • Quinolinic acid stimulates somatostatin gene expression in cultured rat cortical neurons
    • Patel SC, Papachristou DN, Patel YC, (1991) Quinolinic acid stimulates somatostatin gene expression in cultured rat cortical neurons. J Neurochem 56: 1286-1291.
    • (1991) J Neurochem , vol.56 , pp. 1286-1291
    • Patel, S.C.1    Papachristou, D.N.2    Patel, Y.C.3
  • 28
    • 0022993126 scopus 로고
    • Neurons containing NADPH-diaphorase are selectively resistant to quinolinate toxicity
    • Koh JY, Peters S, Choi DW, (1986) Neurons containing NADPH-diaphorase are selectively resistant to quinolinate toxicity. Science 234: 73-76.
    • (1986) Science , vol.234 , pp. 73-76
    • Koh, J.Y.1    Peters, S.2    Choi, D.W.3
  • 29
    • 0028281465 scopus 로고
    • Expression of N-methyl-D-aspartate receptor subunit NR1 messenger RNA by identified striatal somatostatin cells
    • Augood SJ, McGowan EM, Emson PC, (1994) Expression of N-methyl-D-aspartate receptor subunit NR1 messenger RNA by identified striatal somatostatin cells. Neuroscience 59: 7-12.
    • (1994) Neuroscience , vol.59 , pp. 7-12
    • Augood, S.J.1    McGowan, E.M.2    Emson, P.C.3
  • 30
    • 0030218538 scopus 로고    scopus 로고
    • Cellular expression of ionotropic glutamate receptor subunits on specific striatal neuron types and its implication for striatal vulnerability in glutamate receptor-mediated excitotoxicity
    • Chen Q, Veenman CL, Reiner A, (1996) Cellular expression of ionotropic glutamate receptor subunits on specific striatal neuron types and its implication for striatal vulnerability in glutamate receptor-mediated excitotoxicity. Neuroscience 73: 715-731.
    • (1996) Neuroscience , vol.73 , pp. 715-731
    • Chen, Q.1    Veenman, C.L.2    Reiner, A.3
  • 31
    • 51649104282 scopus 로고    scopus 로고
    • Somatostatin in medium-sized aspiny interneurons of striatum is responsible for their preservation in quinolinic acid and N-methyl-D-asparate-induced neurotoxicity
    • Kumar U, (2008) Somatostatin in medium-sized aspiny interneurons of striatum is responsible for their preservation in quinolinic acid and N-methyl-D-asparate-induced neurotoxicity. J Mol Neurosci 35: 345-354.
    • (2008) J Mol Neurosci , vol.35 , pp. 345-354
    • Kumar, U.1
  • 32
    • 0029927787 scopus 로고    scopus 로고
    • Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice
    • Dawson VL, Kizushi VM, Huang PL, Snyder SH, Dawson TM, (1996) Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice. J Neurosci 16: 2479-2487.
    • (1996) J Neurosci , vol.16 , pp. 2479-2487
    • Dawson, V.L.1    Kizushi, V.M.2    Huang, P.L.3    Snyder, S.H.4    Dawson, T.M.5
  • 33
    • 0032780823 scopus 로고    scopus 로고
    • Somatostatin and Its Receptor Family
    • Patel YC, (1999) Somatostatin and Its Receptor Family. Frontiers in Neuroendocrinology 20: 157-198.
    • (1999) Frontiers in Neuroendocrinology , vol.20 , pp. 157-198
    • Patel, Y.C.1
  • 34
    • 4344571483 scopus 로고    scopus 로고
    • Agonist-dependent dissociation of human somatostatin receptor 2 dimers: a role in receptor trafficking
    • Grant M, Collier B, Kumar U, (2004) Agonist-dependent dissociation of human somatostatin receptor 2 dimers: a role in receptor trafficking. J Biol Chem 279: 36179-36183.
    • (2004) J Biol Chem , vol.279 , pp. 36179-36183
    • Grant, M.1    Collier, B.2    Kumar, U.3
  • 35
    • 4644253963 scopus 로고    scopus 로고
    • The role of subtype-specific ligand binding and the C-tail domain in dimer formation of human somatostatin receptors
    • Grant M, Patel RC, Kumar U, (2004) The role of subtype-specific ligand binding and the C-tail domain in dimer formation of human somatostatin receptors. J Biol Chem 279: 38636-38643.
    • (2004) J Biol Chem , vol.279 , pp. 38636-38643
    • Grant, M.1    Patel, R.C.2    Kumar, U.3
  • 36
    • 0034616021 scopus 로고    scopus 로고
    • Receptors for dopamine and somatostatin: formation of hetero-oligomers with enhanced functional activity
    • Rocheville M, Lange DC, Kumar U, Patel SC, Patel RC, et al. (2000) Receptors for dopamine and somatostatin: formation of hetero-oligomers with enhanced functional activity. Science 288: 154-157.
    • (2000) Science , vol.288 , pp. 154-157
    • Rocheville, M.1    Lange, D.C.2    Kumar, U.3    Patel, S.C.4    Patel, R.C.5
  • 37
    • 0037205489 scopus 로고    scopus 로고
    • Heterodimerization of somatostatin and opioid receptors cross-modulates phosphorylation, internalization, and desensitization
    • Pfeiffer M, Koch T, Schroder H, Laugsch M, Hollt V, et al. (2002) Heterodimerization of somatostatin and opioid receptors cross-modulates phosphorylation, internalization, and desensitization. J Biol Chem 277: 19762-19772.
    • (2002) J Biol Chem , vol.277 , pp. 19762-19772
    • Pfeiffer, M.1    Koch, T.2    Schroder, H.3    Laugsch, M.4    Hollt, V.5
  • 38
    • 0141963325 scopus 로고    scopus 로고
    • On the role of somatostatin in seizure control: clues from the hippocampus
    • Binaschi A, Bregola G, Simonato M, (2003) On the role of somatostatin in seizure control: clues from the hippocampus. Rev Neurosci 14: 285-301.
    • (2003) Rev Neurosci , vol.14 , pp. 285-301
    • Binaschi, A.1    Bregola, G.2    Simonato, M.3
  • 39
    • 0036694755 scopus 로고    scopus 로고
    • Neuropeptides involved in the pathophysiology of schizophrenia and major depression
    • De Wied D, Sigling HO, (2002) Neuropeptides involved in the pathophysiology of schizophrenia and major depression. Neurotox Res 4: 453-468.
    • (2002) Neurotox Res , vol.4 , pp. 453-468
    • de Wied, D.1    Sigling, H.O.2
  • 40
    • 1642514618 scopus 로고    scopus 로고
    • The potential of activation of somatostatinergic neurotransmission with FK960 in Alzheimer's disease
    • Doggrell SA, (2004) The potential of activation of somatostatinergic neurotransmission with FK960 in Alzheimer's disease. Expert Opin Investig Drugs 13: 69-72.
    • (2004) Expert Opin Investig Drugs , vol.13 , pp. 69-72
    • Doggrell, S.A.1
  • 41
    • 0030660352 scopus 로고    scopus 로고
    • Neurodegeneration of somatostatin-immunoreactive neurons in HIV encephalitis
    • Fox L, Alford M, Achim C, Mallory M, Masliah E, (1997) Neurodegeneration of somatostatin-immunoreactive neurons in HIV encephalitis. J Neuropathol Exp Neurol 56: 360-368.
    • (1997) J Neuropathol Exp Neurol , vol.56 , pp. 360-368
    • Fox, L.1    Alford, M.2    Achim, C.3    Mallory, M.4    Masliah, E.5
  • 42
    • 23444452105 scopus 로고    scopus 로고
    • Expression of somatostatin receptor subtypes (SSTR1-5) in Alzheimer's disease brain: An immunohistochemical analysis
    • Kumar U, (2005) Expression of somatostatin receptor subtypes (SSTR1-5) in Alzheimer's disease brain: An immunohistochemical analysis. Neuroscience 134: 525-538.
    • (2005) Neuroscience , vol.134 , pp. 525-538
    • Kumar, U.1
  • 44
    • 33845205770 scopus 로고    scopus 로고
    • Mice heterozygous for neurotrophin-3 display enhanced vulnerability to excitotoxicity in the striatum through increased expression of N-methyl-D-aspartate receptors
    • Torres-Peraza J, Pezzi S, Canals JM, Gavalda N, Garcia-Martinez JM, et al. (2007) Mice heterozygous for neurotrophin-3 display enhanced vulnerability to excitotoxicity in the striatum through increased expression of N-methyl-D-aspartate receptors. Neuroscience 144: 462-471.
    • (2007) Neuroscience , vol.144 , pp. 462-471
    • Torres-Peraza, J.1    Pezzi, S.2    Canals, J.M.3    Gavalda, N.4    Garcia-Martinez, J.M.5
  • 45
    • 67549134205 scopus 로고    scopus 로고
    • Expression of somatostatin and somatostatin receptor subtypes in Apolipoprotein D (ApoD) knockout mouse brain: An immunohistochemical analysis
    • Rajput PS, Billova S, Patel SC, Kharmate G, Somvanshi RK, et al. (2009) Expression of somatostatin and somatostatin receptor subtypes in Apolipoprotein D (ApoD) knockout mouse brain: An immunohistochemical analysis. J Chem Neuroanat 38: 20-33.
    • (2009) J Chem Neuroanat , vol.38 , pp. 20-33
    • Rajput, P.S.1    Billova, S.2    Patel, S.C.3    Kharmate, G.4    Somvanshi, R.K.5
  • 46
    • 3042651452 scopus 로고    scopus 로고
    • Deficiency of somatostatin (SST) receptor type 5 (SSTR5) is associated with sexually dimorphic changes in the expression of SST and SST receptors in brain and pancreas
    • Ramirez JL, Grant M, Norman M, Wang XP, Moldovan S, et al. (2004) Deficiency of somatostatin (SST) receptor type 5 (SSTR5) is associated with sexually dimorphic changes in the expression of SST and SST receptors in brain and pancreas. Mol Cell Endocrinol 221: 105-119.
    • (2004) Mol Cell Endocrinol , vol.221 , pp. 105-119
    • Ramirez, J.L.1    Grant, M.2    Norman, M.3    Wang, X.P.4    Moldovan, S.5
  • 47
    • 33646585164 scopus 로고    scopus 로고
    • Calcineurin inhibitors cause an acceleration of the neurological phenotype in a mouse transgenic for the human Huntington's disease mutation
    • Hernandez-Espinosa D, Morton AJ, (2006) Calcineurin inhibitors cause an acceleration of the neurological phenotype in a mouse transgenic for the human Huntington's disease mutation. Brain Res Bull 69: 669-679.
    • (2006) Brain Res Bull , vol.69 , pp. 669-679
    • Hernandez-Espinosa, D.1    Morton, A.J.2
  • 48
    • 58149373434 scopus 로고    scopus 로고
    • Polyglutamine-modulated striatal calpain activity in YAC transgenic huntington disease mouse model: impact on NMDA receptor function and toxicity
    • Cowan CM, Fan MM, Fan J, Shehadeh J, Zhang LY, et al. (2008) Polyglutamine-modulated striatal calpain activity in YAC transgenic huntington disease mouse model: impact on NMDA receptor function and toxicity. J Neurosci 28: 12725-12735.
    • (2008) J Neurosci , vol.28 , pp. 12725-12735
    • Cowan, C.M.1    Fan, M.M.2    Fan, J.3    Shehadeh, J.4    Zhang, L.Y.5
  • 49
    • 37249083913 scopus 로고    scopus 로고
    • Mitochondrial sensitivity and altered calcium handling underlie enhanced NMDA-induced apoptosis in YAC128 model of Huntington's disease
    • Fernandes HB, Baimbridge KG, Church J, Hayden MR, Raymond LA, (2007) Mitochondrial sensitivity and altered calcium handling underlie enhanced NMDA-induced apoptosis in YAC128 model of Huntington's disease. J Neurosci 27: 13614-13623.
    • (2007) J Neurosci , vol.27 , pp. 13614-13623
    • Fernandes, H.B.1    Baimbridge, K.G.2    Church, J.3    Hayden, M.R.4    Raymond, L.A.5
  • 50
    • 69149105165 scopus 로고    scopus 로고
    • Impaired defense mechanism against inflammation, hyperalgesia, and airway hyperreactivity in somatostatin 4 receptor gene-deleted mice
    • Helyes Z, Pinter E, Sandor K, Elekes K, Banvolgyi A, et al. (2009) Impaired defense mechanism against inflammation, hyperalgesia, and airway hyperreactivity in somatostatin 4 receptor gene-deleted mice. Proc Natl Acad Sci U S A 106: 13088-13093.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 13088-13093
    • Helyes, Z.1    Pinter, E.2    Sandor, K.3    Elekes, K.4    Banvolgyi, A.5
  • 51
    • 0033792363 scopus 로고    scopus 로고
    • Involvement of sst2 somatostatin receptor in locomotor, exploratory activity and emotional reactivity in mice
    • Viollet C, Vaillend C, Videau C, Bluet-Pajot MT, Ungerer A, et al. (2000) Involvement of sst2 somatostatin receptor in locomotor, exploratory activity and emotional reactivity in mice. Eur J Neurosci 12: 3761-3770.
    • (2000) Eur J Neurosci , vol.12 , pp. 3761-3770
    • Viollet, C.1    Vaillend, C.2    Videau, C.3    Bluet-Pajot, M.T.4    Ungerer, A.5
  • 52
    • 0033166545 scopus 로고    scopus 로고
    • Beyond the dopamine receptor: the DARPP-32/protein phosphatase-1 cascade
    • Greengard P, Allen PB, Nairn AC, (1999) Beyond the dopamine receptor: the DARPP-32/protein phosphatase-1 cascade. Neuron 23: 435-447.
    • (1999) Neuron , vol.23 , pp. 435-447
    • Greengard, P.1    Allen, P.B.2    Nairn, A.C.3
  • 53
    • 0034652091 scopus 로고    scopus 로고
    • Regulation of the phosphorylation of the dopamine- and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D1, dopamine D2, and adenosine A2A receptors
    • Svenningsson P, Lindskog M, Ledent C, Parmentier M, Greengard P, et al. (2000) Regulation of the phosphorylation of the dopamine- and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D1, dopamine D2, and adenosine A2A receptors. Proc Natl Acad Sci U S A 97: 1856-1860.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 1856-1860
    • Svenningsson, P.1    Lindskog, M.2    Ledent, C.3    Parmentier, M.4    Greengard, P.5
  • 54
    • 34548450155 scopus 로고    scopus 로고
    • Heterooligomerization of human dopamine receptor 2 and somatostatin receptor 2 Co-immunoprecipitation and fluorescence resonance energy transfer analysis
    • Baragli A, Alturaihi H, Watt HL, Abdallah A, Kumar U, (2007) Heterooligomerization of human dopamine receptor 2 and somatostatin receptor 2 Co-immunoprecipitation and fluorescence resonance energy transfer analysis. Cell Signal 19: 2304-2316.
    • (2007) Cell Signal , vol.19 , pp. 2304-2316
    • Baragli, A.1    Alturaihi, H.2    Watt, H.L.3    Abdallah, A.4    Kumar, U.5
  • 55
    • 67650468715 scopus 로고    scopus 로고
    • Colocalization of dopamine receptor subtypes with dopamine and cAMP-regulated phosphoprotein (DARPP-32) in rat brain
    • Rajput PS, Kharmate G, Somvanshi RK, Kumar U, (2009) Colocalization of dopamine receptor subtypes with dopamine and cAMP-regulated phosphoprotein (DARPP-32) in rat brain. Neurosci Res 65: 53-63.
    • (2009) Neurosci Res , vol.65 , pp. 53-63
    • Rajput, P.S.1    Kharmate, G.2    Somvanshi, R.K.3    Kumar, U.4
  • 56
    • 79961168563 scopus 로고    scopus 로고
    • Mechanisms underlying NMDA receptor synaptic/extrasynaptic distribution and function
    • Gladding CM, Raymond LA, (2011) Mechanisms underlying NMDA receptor synaptic/extrasynaptic distribution and function. Mol Cell Neurosci.
    • (2011) Mol Cell Neurosci
    • Gladding, C.M.1    Raymond, L.A.2
  • 57
    • 70450182118 scopus 로고    scopus 로고
    • Coupling of the NMDA receptor to neuroprotective and neurodestructive events
    • Hardingham GE, (2009) Coupling of the NMDA receptor to neuroprotective and neurodestructive events. Biochem Soc Trans 37: 1147-1160.
    • (2009) Biochem Soc Trans , vol.37 , pp. 1147-1160
    • Hardingham, G.E.1
  • 58
    • 77956917231 scopus 로고    scopus 로고
    • Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders
    • Hardingham GE, Bading H, (2010) Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders. Nat Rev Neurosci 11: 682-696.
    • (2010) Nat Rev Neurosci , vol.11 , pp. 682-696
    • Hardingham, G.E.1    Bading, H.2
  • 59
    • 33646518995 scopus 로고    scopus 로고
    • Changes in expression of N-methyl-D-aspartate receptor subunits occur early in the R6/2 mouse model of Huntington's disease
    • Ali NJ, Levine MS, (2006) Changes in expression of N-methyl-D-aspartate receptor subunits occur early in the R6/2 mouse model of Huntington's disease. Dev Neurosci 28: 230-238.
    • (2006) Dev Neurosci , vol.28 , pp. 230-238
    • Ali, N.J.1    Levine, M.S.2
  • 61
    • 77958192164 scopus 로고    scopus 로고
    • Early synaptic pathophysiology in neurodegeneration: insights from Huntington's disease
    • Milnerwood AJ, Raymond LA, (2010) Early synaptic pathophysiology in neurodegeneration: insights from Huntington's disease. Trends Neurosci 33: 513-523.
    • (2010) Trends Neurosci , vol.33 , pp. 513-523
    • Milnerwood, A.J.1    Raymond, L.A.2
  • 62
    • 71349085133 scopus 로고    scopus 로고
    • The role of G-proteins in the dimerisation of human somatostatin receptor types 2 and 5
    • Grant M, Kumar U, (2010) The role of G-proteins in the dimerisation of human somatostatin receptor types 2 and 5. Regul Pept 159: 3-8.
    • (2010) Regul Pept , vol.159 , pp. 3-8
    • Grant, M.1    Kumar, U.2
  • 63
  • 64
    • 0031449996 scopus 로고    scopus 로고
    • The phosphoprotein DARPP-32 mediates cAMP-dependent potentiation of striatal N-methyl-D-aspartate responses
    • Blank T, Nijholt I, Teichert U, Kugler H, Behrsing H, et al. (1997) The phosphoprotein DARPP-32 mediates cAMP-dependent potentiation of striatal N-methyl-D-aspartate responses. Proc Natl Acad Sci U S A 94: 14859-14864.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 14859-14864
    • Blank, T.1    Nijholt, I.2    Teichert, U.3    Kugler, H.4    Behrsing, H.5
  • 65
    • 18544412213 scopus 로고    scopus 로고
    • DARPP chocolate: a caffeinated morsel of striatal signaling
    • Bastia E, Schwarzschild MA, (2003) DARPP chocolate: a caffeinated morsel of striatal signaling. Sci STKE 2003: PE2.
    • (2003) Sci STKE 2003: PE2
    • Bastia, E.1    Schwarzschild, M.A.2
  • 66
    • 0037096376 scopus 로고    scopus 로고
    • Calpain activation in Huntington's disease
    • Gafni J, Ellerby LM, (2002) Calpain activation in Huntington's disease. J Neurosci 22: 4842-4849.
    • (2002) J Neurosci , vol.22 , pp. 4842-4849
    • Gafni, J.1    Ellerby, L.M.2
  • 67
    • 2442631459 scopus 로고    scopus 로고
    • Inhibition of calpain cleavage of huntingtin reduces toxicity: accumulation of calpain/caspase fragments in the nucleus
    • Gafni J, Hermel E, Young JE, Wellington CL, Hayden MR, et al. (2004) Inhibition of calpain cleavage of huntingtin reduces toxicity: accumulation of calpain/caspase fragments in the nucleus. J Biol Chem 279: 20211-20220.
    • (2004) J Biol Chem , vol.279 , pp. 20211-20220
    • Gafni, J.1    Hermel, E.2    Young, J.E.3    Wellington, C.L.4    Hayden, M.R.5
  • 68
    • 0034048845 scopus 로고    scopus 로고
    • Decrease in striatal enkephalin mRNA in mouse models of Huntington's disease
    • Menalled L, Zanjani H, MacKenzie L, Koppel A, Carpenter E, et al. (2000) Decrease in striatal enkephalin mRNA in mouse models of Huntington's disease. Exp Neurol 162: 328-342.
    • (2000) Exp Neurol , vol.162 , pp. 328-342
    • Menalled, L.1    Zanjani, H.2    MacKenzie, L.3    Koppel, A.4    Carpenter, E.5
  • 69
    • 0037004869 scopus 로고    scopus 로고
    • Differential changes in striatal projection neurons in R6/2 transgenic mice for Huntington's disease
    • Sun Z, Del Mar N, Meade C, Goldowitz D, Reiner A, (2002) Differential changes in striatal projection neurons in R6/2 transgenic mice for Huntington's disease. Neurobiol Dis 11: 369-385.
    • (2002) Neurobiol Dis , vol.11 , pp. 369-385
    • Sun, Z.1    Del Mar, N.2    Meade, C.3    Goldowitz, D.4    Reiner, A.5
  • 70
    • 0033500593 scopus 로고    scopus 로고
    • Selective discrimination learning impairments in mice expressing the human Huntington's disease mutation
    • Lione LA, Carter RJ, Hunt MJ, Bates GP, Morton AJ, et al. (1999) Selective discrimination learning impairments in mice expressing the human Huntington's disease mutation. J Neurosci 19: 10428-10437.
    • (1999) J Neurosci , vol.19 , pp. 10428-10437
    • Lione, L.A.1    Carter, R.J.2    Hunt, M.J.3    Bates, G.P.4    Morton, A.J.5
  • 71
    • 0029930179 scopus 로고    scopus 로고
    • Somatostatin receptor subtypes SSTR2 and SSTR5 couple negatively to an L-type Ca2+ current in the pituitary cell line AtT-20
    • Tallent M, Liapakis G, O'Carroll AM, Lolait SJ, Dichter M, et al. (1996) Somatostatin receptor subtypes SSTR2 and SSTR5 couple negatively to an L-type Ca2+ current in the pituitary cell line AtT-20. Neuroscience 71: 1073-1081.
    • (1996) Neuroscience , vol.71 , pp. 1073-1081
    • Tallent, M.1    Liapakis, G.2    O'Carroll, A.M.3    Lolait, S.J.4    Dichter, M.5
  • 72
    • 67349122897 scopus 로고    scopus 로고
    • C-tail mediated modulation of somatostatin receptor type-4 homo- and heterodimerizations and signaling
    • Somvanshi RK, Billova S, Kharmate G, Rajput PS, Kumar U, (2009) C-tail mediated modulation of somatostatin receptor type-4 homo- and heterodimerizations and signaling. Cell Signal 21: 1396-1414.
    • (2009) Cell Signal , vol.21 , pp. 1396-1414
    • Somvanshi, R.K.1    Billova, S.2    Kharmate, G.3    Rajput, P.S.4    Kumar, U.5
  • 73
    • 34548217643 scopus 로고    scopus 로고
    • Colocalization of somatostatin receptor subtypes (SSTR1-5) with somatostatin, NADPH-diaphorase (NADPH-d), and tyrosine hydroxylase in the rat hypothalamus
    • Kumar U, (2007) Colocalization of somatostatin receptor subtypes (SSTR1-5) with somatostatin, NADPH-diaphorase (NADPH-d), and tyrosine hydroxylase in the rat hypothalamus. J Comp Neurol 504: 185-205.
    • (2007) J Comp Neurol , vol.504 , pp. 185-205
    • Kumar, U.1
  • 74
    • 4444355388 scopus 로고    scopus 로고
    • Double-gene ablation of SSTR1 and SSTR5 results in hyperinsulinemia and improved glucose tolerance in mice
    • Wang XP, Norman MA, Yang J, Cheung A, Moldovan S, et al. (2004) Double-gene ablation of SSTR1 and SSTR5 results in hyperinsulinemia and improved glucose tolerance in mice. Surgery 136: 585-592.
    • (2004) Surgery , vol.136 , pp. 585-592
    • Wang, X.P.1    Norman, M.A.2    Yang, J.3    Cheung, A.4    Moldovan, S.5
  • 75
    • 34250175799 scopus 로고    scopus 로고
    • Immunohistochemical expression and colocalization of somatostatin, carboxypeptidase-E and prohormone convertases 1 and 2 in rat brain
    • Billova S, Galanopoulou AS, Seidah NG, Qiu X, Kumar U, (2007) Immunohistochemical expression and colocalization of somatostatin, carboxypeptidase-E and prohormone convertases 1 and 2 in rat brain. Neuroscience 147: 403-418.
    • (2007) Neuroscience , vol.147 , pp. 403-418
    • Billova, S.1    Galanopoulou, A.S.2    Seidah, N.G.3    Qiu, X.4    Kumar, U.5


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