Colocalization of dopamine receptor subtypes with dopamine and cAMP-regulated phosphoprotein (DARPP-32) in rat brain

Neuroscience Research

Volumn 65, Issue 1, 2009, Pages 53-63

  Rajput, Padmesh S ^a   Kharmate, Geetanjali ^a   Somvanshi, Rishi K ^a   Kumar, Ujendra ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Central nervous system; Co immunoprecipitate; Colocalization; DARPP 32; Dopamine; Dopamine receptors; Striatum and cortex

Indexed keywords

DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE 4 RECEPTOR; DOPAMINE 5 RECEPTOR; PHOSPHOPROTEIN DARPP 32;

ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN NERVE CELL; CINGULATE GYRUS; CONTROLLED STUDY; CORPUS STRIATUM; FRONTAL CORTEX; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; TEMPORAL CORTEX; TISSUE DISTRIBUTION;

ANIMALS; BLOTTING, WESTERN; CEREBRAL CORTEX; CORPUS STRIATUM; DOPAMINE AND CAMP-REGULATED PHOSPHOPROTEIN 32; FLUORESCENT ANTIBODY TECHNIQUE; GYRUS CINGULI; MALE; MICROSCOPY, CONFOCAL; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE;

EID: 67650468715     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neures.2009.05.005     Document Type: Article

References (59)

1. Aizman O., Brismar H., Uhlen P., Zettergren E., Levey A.I., Forssberg H., Greengard P., and Aperia A. Anatomical and physiological evidence for D1 and D2 dopamine receptor colocalization in neostriatal neurons. Nat. Neurosci. 3 3 (2000) 226-230
2. Amara S.G., Sonders M.S., Zahniser N.R., Povlock S.L., and Daniels G.M. Molecular physiology and regulation of catecholamine transporters. Adv. Pharmacol. 42 (1998) 164-168
3. Andersson M., Usiello A., Borgkvist A., Pozzi L., Dominguez C., Fienberg A.A., Svenningsson P., Fredholm B.B., Borrelli E., Greengard P., and Fisone G. Cannabinoid action depends on phosphorylation of dopamine- and cAMP-regulated phosphoprotein of 32 kDa at the protein kinase A site in striatal projection neurons. J. Neurosci. 25 37 (2005) 8432-8438
4. Ariano M.A., Wang J., Noblett K.L., Larson E.R., and Sibley D.R. Cellular distribution of the rat D1B receptor in central nervous system using anti-receptor antisera. Brain Res. 746 1-2 (1997) 141-150
5. Bertran-Gonzalez J., Bosch C., Maroteaux M., Matamales M., Herve D., Valjent E., and Girault J.A. Opposing patterns of signaling activation in dopamine D1 and D2 receptor-expressing striatal neurons in response to cocaine and haloperidol. J. Neurosci. 28 22 (2008) 5671-5685
6. Blank T., Nijholt I., Teichert U., Kugler H., Behrsing H., Fienberg A., Greengard P., and Spiess J. The phosphoprotein DARPP-32 mediates cAMP-dependent potentiation of striatal N-methyl-d-aspartate responses. Proc. Natl. Acad. Sci. U.S.A. 94 26 (1997) 14859-14864
7. Borgkvist A., Marcellino D., Fuxe K., Greengard P., and Fisone G. Regulation of DARPP-32 phosphorylation by Delta9-tetrahydrocannabinol. Neuropharmacology 54 1 (2008) 31-35
8. Borgkvist A., Usiello A., Greengard P., and Fisone G. Activation of the cAMP/PKA/DARPP-32 signaling pathway is required for morphine psychomotor stimulation but not for morphine reward. Neuropsychopharmacology 32 9 (2007) 1995-2003
9. Bouthenet M.L., Souil E., Martres M.P., Sokoloff P., Giros B., and Schwartz J.C. Localization of dopamine D3 receptor mRNA in the rat brain using in situ hybridization histochemistry: comparison with dopamine D2 receptor mRNA. Brain Res. 564 2 (1991) 203-219
10. Bunzow J.R., Van Tol H.H., Grandy D.K., Albert P., Salon J., Christie M., Machida C.A., Neve K.A., and Civelli O. Cloning and expression of a rat D2 dopamine receptor cDNA. Nature 336 6201 (1988) 783-787
11. Csillag A., Balint E., Adam A., and Zachar G. The organisation of the basal ganglia in the domestic chick (Gallus domesticus): anatomical localisation of DARPP-32 in relation to glutamate. Brain Res. Bull. 76 3 (2008) 183-191
12. Durstewitz D., Kroner S., Hemmings Jr. H.C., and Gunturkun O. The dopaminergic innervation of the pigeon telencephalon: distribution of DARPP-32 and co-occurrence with glutamate decarboxylase and tyrosine hydroxylase. Neuroscience 83 3 (1998) 763-779
13. Gerfen C.R., Paletzki R., and Worley P. Differences between dorsal and ventral striatum in Drd1a dopamine receptor coupling of dopamine- and cAMP-regulated phosphoprotein-32 to activation of extracellular signal-regulated kinase. J. Neurosci. 28 28 (2008) 7113-7120
14. Greengard P. The neurobiology of slow synaptic transmission. Science 294 5544 (2001) 1024-1030
15. Greengard P., Allen P.B., and Nairn A.C. Beyond the dopamine receptor: the DARPP-32/protein phosphatase-1 cascade. Neuron 23 3 (1999) 435-447
16. Gurevich E.V., Bordelon Y., Shapiro R.M., Arnold S.E., Gur R.E., and Joyce J.N. Mesolimbic dopamine D3 receptors and use of antipsychotics in patients with schizophrenia. A postmortem study. Arch. Gen. Psychiatry 54 3 (1997) 225-232
17. Hyman S.E., and Malenka R.C. Addiction and the brain: the neurobiology of compulsion and its persistence. Nat. Rev. Neurosci. 2 10 (2001) 695-703
18. Jay T.M. Dopamine: a potential substrate for synaptic plasticity and memory mechanisms. Prog. Neurobiol. 69 6 (2003) 375-390
19. Joyce J.N. D2 but not D3 receptors are elevated after 9 or 11 months chronic haloperidol treatment: influence of withdrawal period. Synapse 40 2 (2001) 137-144
20. Khan Z.U., Gutierrez A., Martin R., Penafiel A., Rivera A., and de la Calle A. Dopamine D5 receptors of rat and human brain. Neuroscience 100 4 (2000) 689-699
21. Koob G.F., and Le Moal M. Drug abuse: hedonic homeostatic dysregulation. Science 278 5335 (1997) 52-58
22. Kumar U. Colocalization of somatostatin receptor subtypes (SSTR1-5) with somatostatin, NADPH-diaphorase (NADPH-d), and tyrosine hydroxylase in the rat hypothalamus. J. Comp. Neurol. 504 2 (2007) 185-205
23. Kumar U., and Patel S.C. Immunohistochemical localization of dopamine receptor subtypes (D1R-D5R) in Alzheimer's disease brain. Brain Res. 1131 1 (2007) 187-196
24. Langley K.C., Bergson C., Greengard P., and Ouimet C.C. Co-localization of the D1 dopamine receptor in a subset of DARPP-32-containing neurons in rat caudate-putamen. Neuroscience 78 4 (1997) 977-983
25. Le Moine C., and Bloch B. D1 and D2 dopamine receptor gene expression in the rat striatum: sensitive cRNA probes demonstrate prominent segregation of D1 and D2 mRNAs in distinct neuronal populations of the dorsal and ventral striatum. J. Comp. Neurol. 355 3 (1995) 418-426
26. Lee F.J., Xue S., Pei L., Vukusic B., Chery N., Wang Y., Wang Y.T., Niznik H.B., Yu X.M., and Liu F. Dual regulation of NMDA receptor functions by direct protein-protein interactions with the dopamine D1 receptor. Cell 111 2 (2002) 219-230
27. Lindskog M., Svenningsson P., Fredholm B., Greengard P., and Fisone G. Mu-and delta-opioid receptor agonists inhibit DARPP-32 phosphorylation in distinct populations of striatal projection neurons. Eur. J. Neurosci. 11 6 (1999) 2182-2186
28. Lindskog M., Svenningsson P., Fredholm B.B., Greengard P., and Fisone G. Activation of dopamine D2 receptors decreases DARPP-32 phosphorylation in striatonigral and striatopallidal projection neurons via different mechanisms. Neuroscience 88 4 (1999) 1005-1008
29. Lloyd K., and Hornykiewicz O. Parkinson's disease: activity of l-dopa decarboxylase in discrete brain regions. Science 170 963 (1970) 1212-1213
30. Meador-Woodruff J.H., Mansour A., Grandy D.K., Damask S.P., Civelli O., and Watson Jr. S.J. Distribution of D5 dopamine receptor mRNA in rat brain. Neurosci. Lett. 145 2 (1992) 209-212
31. Missale C., Nash S.R., Robinson S.W., Jaber M., and Caron M.G. Dopamine receptors: from structure to function. Physiol. Rev. 78 1 (1998) 189-225
32. Nairn A.C., Svenningsson P., Nishi A., Fisone G., Girault J.A., and Greengard P. The role of DARPP-32 in the actions of drugs of abuse. Neuropharmacology 47 Suppl. 1 (2004) 14-23
33. Nestler E.J. Molecular basis of long-term plasticity underlying addiction. Nat. Rev. Neurosci. 2 2 (2001) 119-128
34. Nishi A., Bibb J.A., Snyder G.L., Higashi H., Nairn A.C., and Greengard P. Amplification of dopaminergic signaling by a positive feedback loop. Proc. Natl. Acad. Sci. U.S.A. 97 23 (2000) 12840-12845
35. Nishi A., Snyder G.L., and Greengard P. Bidirectional regulation of DARPP-32 phosphorylation by dopamine. J. Neurosci. 17 21 (1997) 8147-8155
36. Ouimet C.C., LaMantia A.S., Goldman-Rakic P., Rakic P., and Greengard P. Immunocytochemical localization of DARPP-32, a dopamine and cyclic-AMP-regulated phosphoprotein, in the primate brain. J. Comp. Neurol. 323 2 (1992) 209-218
37. Ouimet C.C., Langley-Gullion K.C., and Greengard P. Quantitative immunocytochemistry of DARPP-32-expressing neurons in the rat caudato-putamen. Brain Res. 808 1 (1998) 8-12
38. Ouimet C.C., Miller P.E., Hemmings Jr. H.C., Walaas S.I., and Greengard P. DARPP-32, a dopamine- and adenosine 3′:5′-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. III. Immunocytochemical localization. J. Neurosci. 4 1 (1984) 111-124
39. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates. fourth ed. (1998), Academic Press, New York
40. Schnabel R., Metzger M., Jiang S., Hemmings Jr. H.C., Greengard P., and Braun K. Localization of dopamine D1 receptors and dopaminoceptive neurons in the chick forebrain. J. Comp. Neurol. 388 1 (1997) 146-168
41. Scott L., Zelenin S., Malmersjo S., Kowalewski J.M., Markus E.Z., Nairn A.C., Greengard P., Brismar H., and Aperia A. Allosteric changes of the NMDA receptor trap diffusible dopamine 1 receptors in spines. Proc. Natl. Acad. Sci. U.S.A. 103 3 (2006) 762-767
42. Seeman P., Bzowej N.H., Guan H.C., Bergeron C., Reynolds G.P., Bird E.D., Riederer P., Jellinger K., and Tourtellotte W.W. Human brain D1 and D2 dopamine receptors in schizophrenia, Alzheimer's, Parkinson's, and Huntington's diseases. Neuropsychopharmacology 1 1 (1987) 5-15
43. Seeman P., and Van Tol H.H. Dopamine receptor pharmacology. Curr. Opin. Neurol. Neurosurg. 6 4 (1993) 602-608
44. Self D.W., Barnhart W.J., Lehman D.A., and Nestler E.J. Opposite modulation of cocaine-seeking behavior by D1- and D2-like dopamine receptor agonists. Science 271 5255 (1996) 1586-1589
45. Shin Y., Kumar U., Patel Y., Patel S.C., and Sidhu A. Differential expression of D2-like dopamine receptors in the kidney of the spontaneously hypertensive rat. J. Hypertens. 21 1 (2003) 199-207
46. Sidhu A., Kumar U., Uh M., and Patel S. Diminished expression of renal dopamine D1A receptors in the kidney inner medulla of the spontaneously hypertensive rat. J. Hypertens. 16 5 (1998) 601-608
47. Sotnikova T.D., Beaulieu J.M., Gainetdinov R.R., and Caron M.G. Molecular biology, pharmacology and functional role of the plasma membrane dopamine transporter. CNS Neurol. Disord. Drug Targets 5 1 (2006) 45-56
48. Sunahara R.K., Guan H.C., O'Dowd B.F., Seeman P., Laurier L.G., Ng G., George S.R., Torchia J., Van Tol H.H., and Niznik H.B. Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1. Nature 350 6319 (1991) 614-619
49. Surmeier D.J., Reiner A., Levine M.S., and Ariano M.A. Are neostriatal dopamine receptors co-localized?. Trends Neurosci. 16 8 (1993) 299-305
50. Svenningsson P., Lindskog M., Ledent C., Parmentier M., Greengard P., Fredholm B.B., and Fisone G. Regulation of the phosphorylation of the dopamine- and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D1, dopamine D2, and adenosine A2A receptors. Proc. Natl. Acad. Sci. U.S.A. 97 4 (2000) 1856-1860
51. Svenningsson P., Nairn A.C., and Greengard P. DARPP-32 mediates the actions of multiple drugs of abuse. AAPS J. 7 2 (2005) E353-360
52. Svenningsson P., Nishi A., Fisone G., Girault J.A., Nairn A.C., and Greengard P. DARPP-32: an integrator of neurotransmission. Annu. Rev. Pharmacol. Toxicol. 44 (2004) 269-296
53. Tiberi M., Jarvie K.R., Silvia C., Falardeau P., Gingrich J.A., Godinot N., Bertrand L., Yang-Feng T.L., Fremeau Jr. R.T., and Caron M.G. Cloning, molecular characterization, and chromosomal assignment of a gene encoding a second D1 dopamine receptor subtype: differential expression pattern in rat brain compared with the D1A receptor. Proc. Natl. Acad. Sci. U.S.A. 88 17 (1991) 7491-7495
54. Torres-Peraza J., Pezzi S., Canals J.M., Gavalda N., Garcia-Martinez J.M., Perez-Navarro E., and Alberch J. Mice heterozygous for neurotrophin-3 display enhanced vulnerability to excitotoxicity in the striatum through increased expression of N-methyl-d-aspartate receptors. Neuroscience 144 2 (2007) 462-471
55. Valjent E., Corvol J.C., Pages C., Besson M.J., Maldonado R., and Caboche J. Involvement of the extracellular signal-regulated kinase cascade for cocaine-rewarding properties. J. Neurosci. 20 23 (2000) 8701-8709
56. Van Tol H.H., Bunzow J.R., Guan H.C., Sunahara R.K., Seeman P., Niznik H.B., and Civelli O. Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine. Nature 350 6319 (1991) 610-614
57. Walaas S.I., Aswad D.W., and Greengard P. A dopamine- and cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. Nature 301 5895 (1983) 69-71
58. Walaas S.I., and Greengard P. DARPP-32, a dopamine- and adenosine 3′:5′-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Regional and cellular distribution in the rat brain. J. Neurosci. 4 1 (1984) 84-98
59. Zhang T.A., Hendricson A.W., and Morrisett R.A. Dual synaptic sites of D(1)-dopaminergic regulation of ethanol sensitivity of NMDA receptors in nucleus accumbens. Synapse 58 1 (2005) 30-44