메뉴 건너뛰기




Volumn 22, Issue 9, 2011, Pages 382-387

Towards a serotonin-dependent leptin roadmap in the brain

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; LEPTIN; SEROTONIN; TRYPTOPHAN HYDROXYLASE;

EID: 80052388240     PISSN: 10432760     EISSN: 18793061     Source Type: Journal    
DOI: 10.1016/j.tem.2011.04.006     Document Type: Review
Times cited : (47)

References (52)
  • 1
    • 0141737573 scopus 로고    scopus 로고
    • Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass
    • Ducy P., et al. Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass. Cell 2000, 100:197-207.
    • (2000) Cell , vol.100 , pp. 197-207
    • Ducy, P.1
  • 2
    • 0035936764 scopus 로고    scopus 로고
    • Obesity and the regulation of energy balance
    • Spiegelman B.M., Flier J.S. Obesity and the regulation of energy balance. Cell 2001, 104:531-543.
    • (2001) Cell , vol.104 , pp. 531-543
    • Spiegelman, B.M.1    Flier, J.S.2
  • 3
    • 0028139089 scopus 로고
    • Positional cloning of the mouse obese gene and its human homologue
    • Zhang Y., et al. Positional cloning of the mouse obese gene and its human homologue. Nature 1994, 372:425-432.
    • (1994) Nature , vol.372 , pp. 425-432
    • Zhang, Y.1
  • 4
    • 2442654859 scopus 로고
    • Identification and expression cloning of a leptin receptor OB-R
    • Tartaglia L.A., et al. Identification and expression cloning of a leptin receptor OB-R. Cell 1995, 83:1263-1271.
    • (1995) Cell , vol.83 , pp. 1263-1271
    • Tartaglia, L.A.1
  • 5
    • 0036847619 scopus 로고    scopus 로고
    • Leptin regulates bone formation via the sympathetic nervous system
    • Takeda S., et al. Leptin regulates bone formation via the sympathetic nervous system. Cell 2002, 111:305-317.
    • (2002) Cell , vol.111 , pp. 305-317
    • Takeda, S.1
  • 6
    • 15844384047 scopus 로고    scopus 로고
    • Leptin regulation of bone resorption by the sympathetic nervous system and CART
    • Elefteriou F., et al. Leptin regulation of bone resorption by the sympathetic nervous system and CART. Nature 2005, 434:514-520.
    • (2005) Nature , vol.434 , pp. 514-520
    • Elefteriou, F.1
  • 7
    • 0037118285 scopus 로고    scopus 로고
    • High bone density due to a mutation in LDL-receptor-related protein 5
    • Boyden L.M., et al. High bone density due to a mutation in LDL-receptor-related protein 5. N. Engl. J. Med. 2002, 346:1513-1521.
    • (2002) N. Engl. J. Med. , vol.346 , pp. 1513-1521
    • Boyden, L.M.1
  • 8
    • 33751538595 scopus 로고    scopus 로고
    • Increased leptin expression in common Carp (Cyprinus carpio) after food intake but not after fasting or feeding to satiation
    • Huising M.O., et al. Increased leptin expression in common Carp (Cyprinus carpio) after food intake but not after fasting or feeding to satiation. Endocrinology 2006, 147:5786-5797.
    • (2006) Endocrinology , vol.147 , pp. 5786-5797
    • Huising, M.O.1
  • 9
    • 78049518505 scopus 로고    scopus 로고
    • The central regulation of bone mass, the first link between bone remodeling and energy metabolism
    • Karsenty G., Oury F. The central regulation of bone mass, the first link between bone remodeling and energy metabolism. J. Clin. Endocrinol. Metab. 2010, 95:4795-4801.
    • (2010) J. Clin. Endocrinol. Metab. , vol.95 , pp. 4795-4801
    • Karsenty, G.1    Oury, F.2
  • 10
    • 0344450708 scopus 로고    scopus 로고
    • A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
    • Clement K., et al. A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction. Nature 1998, 392:398-401.
    • (1998) Nature , vol.392 , pp. 398-401
    • Clement, K.1
  • 11
    • 0030273540 scopus 로고    scopus 로고
    • Identification of a developmentally regulated protein tyrosine phosphatase in embryonic stem cells that is a marker of pluripotential epiblast and early mesoderm
    • Lee K., et al. Identification of a developmentally regulated protein tyrosine phosphatase in embryonic stem cells that is a marker of pluripotential epiblast and early mesoderm. Mech. Dev. 1996, 59:153-164.
    • (1996) Mech. Dev. , vol.59 , pp. 153-164
    • Lee, K.1
  • 12
    • 0032014836 scopus 로고    scopus 로고
    • A leptin missense mutation associated with hypogonadism and morbid obesity
    • Strobel A., et al. A leptin missense mutation associated with hypogonadism and morbid obesity. Nat. Genet. 1998, 18:213-215.
    • (1998) Nat. Genet. , vol.18 , pp. 213-215
    • Strobel, A.1
  • 13
    • 0030878110 scopus 로고    scopus 로고
    • Congenital leptin deficiency is associated with severe early-onset obesity in humans
    • Montague C.T., et al. Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 1997, 387:903-908.
    • (1997) Nature , vol.387 , pp. 903-908
    • Montague, C.T.1
  • 14
    • 13344259300 scopus 로고    scopus 로고
    • Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice
    • Chen H., et al. Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 1996, 84:491-495.
    • (1996) Cell , vol.84 , pp. 491-495
    • Chen, H.1
  • 15
    • 34248227278 scopus 로고    scopus 로고
    • Mice lacking inhibitory leptin receptor signals are lean with normal endocrine function
    • Bjornholm M., et al. Mice lacking inhibitory leptin receptor signals are lean with normal endocrine function. J. Clin. Invest. 2007, 117:1354-1360.
    • (2007) J. Clin. Invest. , vol.117 , pp. 1354-1360
    • Bjornholm, M.1
  • 16
    • 58149498221 scopus 로고    scopus 로고
    • Dissociation of the neuronal regulation of bone mass and energy metabolism by leptin in vivo
    • Shi Y., et al. Dissociation of the neuronal regulation of bone mass and energy metabolism by leptin in vivo. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:20529-20533.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 20529-20533
    • Shi, Y.1
  • 17
    • 0031010408 scopus 로고    scopus 로고
    • Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues
    • Fei H., et al. Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues. Proc. Natl. Acad. Sci. U.S.A. 1997, 94:7001-7005.
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 7001-7005
    • Fei, H.1
  • 18
    • 0033944070 scopus 로고    scopus 로고
    • Leptin regulation of neuroendocrine systems
    • Ahima R.S., et al. Leptin regulation of neuroendocrine systems. Front. Neuroendocrinol. 2000, 21:263-307.
    • (2000) Front. Neuroendocrinol. , vol.21 , pp. 263-307
    • Ahima, R.S.1
  • 19
    • 84990756135 scopus 로고
    • Hypothalamic lesions and adipocity in the rat
    • Hetherington A.W., Ranson S.W. Hypothalamic lesions and adipocity in the rat. Anat. Rec. 1940, 78:149.
    • (1940) Anat. Rec. , vol.78 , pp. 149
    • Hetherington, A.W.1    Ranson, S.W.2
  • 20
    • 84981834057 scopus 로고
    • The relation of various hypothalamic lesions to adiposity in the rat
    • Hetherington A.W., Ranson S.W. The relation of various hypothalamic lesions to adiposity in the rat. J. Comp. Neurol. 1942, 76:475-499.
    • (1942) J. Comp. Neurol. , vol.76 , pp. 475-499
    • Hetherington, A.W.1    Ranson, S.W.2
  • 21
    • 0000833791 scopus 로고
    • Mechanisms of the development of obesity in animals with hypothalamic lesions
    • Brobeck J.R. Mechanisms of the development of obesity in animals with hypothalamic lesions. Physiol. Rev. 1946, 26:541-559.
    • (1946) Physiol. Rev. , vol.26 , pp. 541-559
    • Brobeck, J.R.1
  • 22
    • 84964125510 scopus 로고
    • Localization of a feeding center in the hypothalamus of the rat
    • Anand B.K., Brobeck J.R. Localization of a feeding center in the hypothalamus of the rat. Proc. Soc. Exp. Biol. Med. 1951, 77:323-324.
    • (1951) Proc. Soc. Exp. Biol. Med. , vol.77 , pp. 323-324
    • Anand, B.K.1    Brobeck, J.R.2
  • 23
    • 0014668762 scopus 로고
    • Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate
    • Olney J.W. Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate. Science 1969, 164:719-721.
    • (1969) Science , vol.164 , pp. 719-721
    • Olney, J.W.1
  • 24
    • 0030737953 scopus 로고    scopus 로고
    • Physiological response to long-term peripheral and central leptin infusion in lean and obese mice
    • Halaas J.L., et al. Physiological response to long-term peripheral and central leptin infusion in lean and obese mice. Proc. Natl. Acad. Sci. U.S.A. 1997, 94:8878-8883.
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 8878-8883
    • Halaas, J.L.1
  • 25
    • 2942733252 scopus 로고    scopus 로고
    • Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis
    • Balthasar N., et al. Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis. Neuron 2004, 42:983-991.
    • (2004) Neuron , vol.42 , pp. 983-991
    • Balthasar, N.1
  • 26
    • 69449083603 scopus 로고    scopus 로고
    • A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure
    • Yadav V.K., et al. A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure. Cell 2009, 138:976-989.
    • (2009) Cell , vol.138 , pp. 976-989
    • Yadav, V.K.1
  • 27
    • 34347262073 scopus 로고    scopus 로고
    • Association of low bone mineral density with selective serotonin reuptake inhibitor use by older men
    • Haney E.M., et al. Association of low bone mineral density with selective serotonin reuptake inhibitor use by older men. Arch. Intern. Med. 2007, 167:1246-1251.
    • (2007) Arch. Intern. Med. , vol.167 , pp. 1246-1251
    • Haney, E.M.1
  • 28
    • 0032213967 scopus 로고    scopus 로고
    • Serotonin neuronal function and selective serotonin reuptake inhibitor treatment in anorexia and bulimia nervosa
    • Kaye W., et al. Serotonin neuronal function and selective serotonin reuptake inhibitor treatment in anorexia and bulimia nervosa. Biol. Psychiatry 1998, 44:825-838.
    • (1998) Biol. Psychiatry , vol.44 , pp. 825-838
    • Kaye, W.1
  • 29
    • 52549085920 scopus 로고    scopus 로고
    • Osteoporosis after combined use of a neuroleptic and antidepressants
    • Laekeman G., et al. Osteoporosis after combined use of a neuroleptic and antidepressants. Pharm. World Sci. 2008, 30:613-616.
    • (2008) Pharm. World Sci. , vol.30 , pp. 613-616
    • Laekeman, G.1
  • 30
    • 33846440508 scopus 로고    scopus 로고
    • Effect of selective serotonin reuptake inhibitors on the risk of fracture
    • Richards J.B., et al. Effect of selective serotonin reuptake inhibitors on the risk of fracture. Arch. Intern. Med. 2007, 167:188-194.
    • (2007) Arch. Intern. Med. , vol.167 , pp. 188-194
    • Richards, J.B.1
  • 31
    • 54449089554 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibiting antidepressants are associated with an increased risk of nonvertebral fractures
    • Ziere G., et al. Selective serotonin reuptake inhibiting antidepressants are associated with an increased risk of nonvertebral fractures. J. Clin. Psychopharmacol. 2008, 28:411-417.
    • (2008) J. Clin. Psychopharmacol. , vol.28 , pp. 411-417
    • Ziere, G.1
  • 32
    • 0029362878 scopus 로고
    • Serotonin receptors. Genetic insights into serotonin function
    • Heath M.J., Hen R. Serotonin receptors. Genetic insights into serotonin function. Curr. Biol. 1995, 5:997-999.
    • (1995) Curr. Biol. , vol.5 , pp. 997-999
    • Heath, M.J.1    Hen, R.2
  • 33
    • 0037414862 scopus 로고    scopus 로고
    • Synthesis of serotonin by a second tryptophan hydroxylase isoform
    • Walther D.J., et al. Synthesis of serotonin by a second tryptophan hydroxylase isoform. Science 2003, 299:76.
    • (2003) Science , vol.299 , pp. 76
    • Walther, D.J.1
  • 34
    • 0026474532 scopus 로고
    • Platelet and whole blood serotonin content in depressed inpatients: correlations with acute and life-time psychopathology
    • Mann J.J., et al. Platelet and whole blood serotonin content in depressed inpatients: correlations with acute and life-time psychopathology. Biol. Psychiatry 1992, 32:243-257.
    • (1992) Biol. Psychiatry , vol.32 , pp. 243-257
    • Mann, J.J.1
  • 35
    • 77958523915 scopus 로고    scopus 로고
    • CREB mediates brain serotonin regulation of bone mass through its expression in ventromedial hypothalamic neurons
    • Oury F., et al. CREB mediates brain serotonin regulation of bone mass through its expression in ventromedial hypothalamic neurons. Genes Dev. 2010, 24:2330-2342.
    • (2010) Genes Dev. , vol.24 , pp. 2330-2342
    • Oury, F.1
  • 36
    • 78651495664 scopus 로고    scopus 로고
    • Leptin-dependent serotonin control of appetite: temporal specificity, transcriptional regulation, and therapeutic implications
    • Yadav V.K., et al. Leptin-dependent serotonin control of appetite: temporal specificity, transcriptional regulation, and therapeutic implications. J. Exp. Med. 2011, 208:41-52.
    • (2011) J. Exp. Med. , vol.208 , pp. 41-52
    • Yadav, V.K.1
  • 37
    • 0021846661 scopus 로고
    • Low doses of the putative serotonin agonist 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) elicit feeding in the rat
    • Dourish C.T., et al. Low doses of the putative serotonin agonist 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) elicit feeding in the rat. Psychopharmacol. (Berl.) 1985, 86:197-204.
    • (1985) Psychopharmacol. (Berl.) , vol.86 , pp. 197-204
    • Dourish, C.T.1
  • 38
    • 0024244472 scopus 로고
    • Relationship of increased food intake and plasma ACTH levels to 5-HT1A receptor activation in rats
    • Gilbert F., et al. Relationship of increased food intake and plasma ACTH levels to 5-HT1A receptor activation in rats. Psychoneuroendocrinology 1988, 13:471-478.
    • (1988) Psychoneuroendocrinology , vol.13 , pp. 471-478
    • Gilbert, F.1
  • 39
    • 0023721864 scopus 로고
    • MDL 72832, a selective 5-HT1A receptor ligand, stereospecifically increases food intake
    • Neill J.C., Cooper S.J. MDL 72832, a selective 5-HT1A receptor ligand, stereospecifically increases food intake. Eur. J. Pharmacol. 1988, 151:329-332.
    • (1988) Eur. J. Pharmacol. , vol.151 , pp. 329-332
    • Neill, J.C.1    Cooper, S.J.2
  • 40
    • 0026613774 scopus 로고
    • Behavioral profile of the 5HT1A receptor antagonist (S)-UH-301 in rodents and monkeys
    • Moreau J.L., et al. Behavioral profile of the 5HT1A receptor antagonist (S)-UH-301 in rodents and monkeys. Brain Res. Bull. 1992, 29:901-904.
    • (1992) Brain Res. Bull. , vol.29 , pp. 901-904
    • Moreau, J.L.1
  • 41
    • 0031721271 scopus 로고    scopus 로고
    • Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene
    • Nonogaki K., et al. Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene. Nat. Med. 1998, 4:1152-1156.
    • (1998) Nat. Med. , vol.4 , pp. 1152-1156
    • Nonogaki, K.1
  • 42
    • 44349100977 scopus 로고    scopus 로고
    • Serotonin regulates C. elegans fat and feeding through independent molecular mechanisms
    • Srinivasan S., et al. Serotonin regulates C. elegans fat and feeding through independent molecular mechanisms. Cell Metab. 2008, 7:533-544.
    • (2008) Cell Metab. , vol.7 , pp. 533-544
    • Srinivasan, S.1
  • 43
    • 0030218856 scopus 로고    scopus 로고
    • Metergoline antagonizes fluoxetine-induced suppression of food intake but not changes in the behavioural satiety sequence
    • Halford J.C., Blundell J.E. Metergoline antagonizes fluoxetine-induced suppression of food intake but not changes in the behavioural satiety sequence. Pharmacol. Biochem. Behav. 1996, 54:745-751.
    • (1996) Pharmacol. Biochem. Behav. , vol.54 , pp. 745-751
    • Halford, J.C.1    Blundell, J.E.2
  • 44
    • 0031596722 scopus 로고    scopus 로고
    • Infusion of the serotonin1B (5-HT1B) agonist CP-93,129 into the parabrachial nucleus potently and selectively reduces food intake in rats
    • Lee M.D., et al. Infusion of the serotonin1B (5-HT1B) agonist CP-93,129 into the parabrachial nucleus potently and selectively reduces food intake in rats. Psychopharmacol. (Berl.) 1998, 136:304-307.
    • (1998) Psychopharmacol. (Berl.) , vol.136 , pp. 304-307
    • Lee, M.D.1
  • 45
    • 0023678368 scopus 로고
    • Evidence that hypophagia induced by mCPP and TFMPP requires 5-HT1C and 5-HT1B receptors; hypophagia induced by RU 24969 only requires 5-HT1B receptors
    • Kennett G.A., Curzon G. Evidence that hypophagia induced by mCPP and TFMPP requires 5-HT1C and 5-HT1B receptors; hypophagia induced by RU 24969 only requires 5-HT1B receptors. Psychopharmacol. (Berl.) 1988, 96:93-100.
    • (1988) Psychopharmacol. (Berl.) , vol.96 , pp. 93-100
    • Kennett, G.A.1    Curzon, G.2
  • 46
    • 0028298214 scopus 로고
    • An examination of the behavioural specificity of hypophagia induced by 5-HT1B, 5-HT1C and 5-HT2 receptor agonists using the post-prandial satiety sequence in rats
    • Kitchener S.J., Dourish C.T. An examination of the behavioural specificity of hypophagia induced by 5-HT1B, 5-HT1C and 5-HT2 receptor agonists using the post-prandial satiety sequence in rats. Psychopharmacol. (Berl) 1994, 113:369-377.
    • (1994) Psychopharmacol. (Berl) , vol.113 , pp. 369-377
    • Kitchener, S.J.1    Dourish, C.T.2
  • 47
    • 0030903068 scopus 로고    scopus 로고
    • RS-102221: a novel high affinity and selective, 5-HT2C receptor antagonist
    • Bonhaus D.W., et al. RS-102221: a novel high affinity and selective, 5-HT2C receptor antagonist. Neuropharmacology 1997, 36:621-629.
    • (1997) Neuropharmacology , vol.36 , pp. 621-629
    • Bonhaus, D.W.1
  • 48
    • 77950858037 scopus 로고    scopus 로고
    • Leptin accumulation in hypothalamic and dorsal raphe neurons is inversely correlated with brain serotonin content
    • Fernandez-Galaz M.C. Leptin accumulation in hypothalamic and dorsal raphe neurons is inversely correlated with brain serotonin content. Brain Res. 2010, 1329:194-202.
    • (2010) Brain Res. , vol.1329 , pp. 194-202
    • Fernandez-Galaz, M.C.1
  • 49
    • 0842308719 scopus 로고    scopus 로고
    • The role of leptin-STAT3 signaling in neuroendocrine function: an integrative perspective
    • Bates S.H., Myers M.G. The role of leptin-STAT3 signaling in neuroendocrine function: an integrative perspective. J. Mol. Med. 2004, 82:12-20.
    • (2004) J. Mol. Med. , vol.82 , pp. 12-20
    • Bates, S.H.1    Myers, M.G.2
  • 50
    • 0028931604 scopus 로고
    • Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors
    • Stahl N., et al. Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors. Science 1995, 267:1349-1353.
    • (1995) Science , vol.267 , pp. 1349-1353
    • Stahl, N.1
  • 51
    • 0031040793 scopus 로고    scopus 로고
    • Leptin receptor (OB-R) signaling Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization
    • White D.W., et al. Leptin receptor (OB-R) signaling Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization. J. Biol. Chem. 1997, 272:4065-4071.
    • (1997) J. Biol. Chem. , vol.272 , pp. 4065-4071
    • White, D.W.1
  • 52
    • 0034640508 scopus 로고    scopus 로고
    • Activation of downstream signals by the long form of the leptin receptor
    • Banks A.S., et al. Activation of downstream signals by the long form of the leptin receptor. J. Biol. Chem. 2000, 275:14563-14572.
    • (2000) J. Biol. Chem. , vol.275 , pp. 14563-14572
    • Banks, A.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.