Improved host defense against septic peritonitis in mice lacking MyD88 and TRIF is linked to a normal interferon response

Journal of Leukocyte Biology

Volumn 90, Issue 3, 2011, Pages 613-620

  Reim, Daniel ^a   Rossmann Bloeck, Tanja ^a   Jusek, Gabriela ^a   da Costa, Olivia Prazeres ^b   Holzmann, Bernhard ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Interferons; Sepsis; Toll like receptors

Indexed keywords

ALPHA BETA INTERFERON RECEPTOR; BETA INTERFERON; CYTOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GUANOSINE TRIPHOSPHATASE; INTERFERON; INTERLEUKIN 10; MESSENGER RNA; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN P47; SYNAPTOTAGMIN I; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL CLEARANCE; CONTROLLED STUDY; HOST RESISTANCE; INFECTION RESISTANCE; INNATE IMMUNITY; MACROPHAGE; MOUSE; NONHUMAN; PERITONITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SEPSIS;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; BONE MARROW; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION PROFILING; IMMUNITY, INNATE; INTERFERONS; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PERITONITIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEPSIS; SIGNAL TRANSDUCTION; SURVIVAL RATE;

BACTERIA (MICROORGANISMS); MUS;

EID: 80052387515     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.1110602     Document Type: Article

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