Hypoxia leads to Na,K-ATPase downregulation via Ca 2+ release-activated Ca 2+ channels and AMPK activation

Molecular and Cellular Biology

Volumn 31, Issue 17, 2011, Pages 3546-3556

  Gusarova, Galina A ^a,c   Trejo, Humberto E ^a   Dada, Laura A ^a   Briva, Arturo ^a,b   Welch, Lynn C ^a   Hamanaka, Robert B ^a   Mutlu, Gökhan M ^a   Chandel, Navdeep S ^a   Prakriya, Murali ^a   Sznajder, Jacob I ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b DEPARTAMENTO DE BIOQUÍMICA   (Uruguay)

^c Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 BIS(2 AMINOPHENOXY)ETHANE N,N,N',N' TETRAACETIC ACID ACETOXYMETHYL ESTER; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENYLATE KINASE; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL; CALMODULIN; CALMODULIN DEPENDENT KINASE KINASE BETA; EUKARION 134; HYPOXIA INDUCIBLE FACTOR 1ALPHA; NIFEDIPINE; REACTIVE OXYGEN METABOLITE; STO 609; STROMAL INTERACTION MOLECULE 1; THAPSIGARGIN; UNCLASSIFIED DRUG;

ALVEOLAR FLUID REABSORPTION IMPAIRMENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL HYPOXIA; CONTROLLED STUDY; ENDOCYTOSIS; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; LUNG ALVEOLUS; LUNG DISEASE; MALE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANOXIA; BLOTTING, WESTERN; CALCIUM; CALCIUM CHANNELS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE; CELL HYPOXIA; CELL LINE, TUMOR; CELLS, CULTURED; DOWN-REGULATION; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; HEK293 CELLS; HUMANS; LUMINESCENT PROTEINS; LUNG; MALE; MEMBRANE PROTEINS; NEOPLASM PROTEINS; PULMONARY ALVEOLI; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; SODIUM-POTASSIUM-EXCHANGING ATPASE;

RATTUS;

EID: 80052325761     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.05114-11     Document Type: Article

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