Involvement of phorbol-12-myristate-13-acetate-induced protein 1 in goniothalamin-induced TP53-dependent and -independent apoptosis in hepatocellular carcinoma-derived cells

Toxicology and Applied Pharmacology

Volumn 256, Issue 1, 2011, Pages 8-23

  Kuo, Kung Kai ^a   Chen, Yi Ling ^b,c   Chen, Lih Ren ^c,d   Li, Chien Feng ^b,e,f   Lan, Yu Hsuan ^g   Chang, Fang Rong ^h   Wu, Yang Chang ^g   Shiue, Yow Ling ^b  

^a KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^c FISHERIES RESEARCH INSTITUTE   (Taiwan)

^d SOUTHERN TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^e CHI MEI MEDICAL CENTER   (Taiwan)

^f NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^g CHINA MEDICAL UNIVERSITY   (Taiwan)

^h KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Goniothalamin (GTN); Hep 3B; Phorbol 12 myristate 13 acetate induced protein 1 (PMAIP1); SK Hep1; Tumor protein p53 (TP53)

Indexed keywords

CASPASE 3; CYTOCHROME C; GONIOTHALAMIN; PROTEIN NOXA; PROTEIN P53; PYRONE DERIVATIVE; REACTIVE OXYGEN METABOLITE; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOSOLIC FRACTION; ENZYME ACTIVITY; FLOW CYTOMETRY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LIVER CELL CARCINOMA; MITOCHONDRION; PROTEIN CLEAVAGE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE;

APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; HUMANS; LIVER NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRONES; REACTIVE OXYGEN SPECIES; TRANSCRIPTIONAL ACTIVATION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 80052322406     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2011.07.002     Document Type: Article

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