Vaccine platforms combining Circumsporozoite protein and potent immune modulators, rEA or EAT-2, Paradoxically result in opposing immune responses

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Schuldt, Nathaniel J ^a   Aldhamen, Yasser A ^b   Appledorn, Daniel M ^b   Seregin, Sergey S ^b   Kousa, Youssef ^c,d   Godbehere, Sarah ^b   Amalfitano, Andrea ^a,b,d  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b NONE   (United States)

^c Michigan State University   (United States)

^d MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CD150 ANTIGEN; CHEMOKINE; CIRCUMSPOROZOITE PROTEIN; CYTOKINE; EAT 2 ADAPTOR PROTEIN; GAMMA INTERFERON; MALARIA VACCINE; PROTEIN SUBUNIT; UNCLASSIFIED DRUG; CIRCUMSPOROZOITE PROTEIN, PROTOZOAN; IMMUNOLOGIC FACTOR; PROTOZOAL PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TOLL LIKE RECEPTOR; VACCINE;

ADAPTIVE IMMUNITY; ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNE RESPONSE; IMMUNOSTIMULATION; IN VIVO STUDY; MALARIA; MALE; MOUSE; NONHUMAN; OPEN READING FRAME; PLASMODIUM FALCIPARUM; SPLEEN CELL; T LYMPHOCYTE; ANIMAL; ANTIBODY SPECIFICITY; ANTIGEN PRESENTATION; BAGG ALBINO MOUSE; DRUG POTENTIATION; GENETICS; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; INNATE IMMUNITY;

ADENOVIRIDAE; MUS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOVIRIDAE; ANIMALS; ANTIBODY SPECIFICITY; ANTIGEN PRESENTATION; B-LYMPHOCYTES; IMMUNE TOLERANCE; IMMUNITY, CELLULAR; IMMUNITY, INNATE; IMMUNOLOGIC FACTORS; MALE; MICE; MICE, INBRED BALB C; PROTOZOAN PROTEINS; T-LYMPHOCYTES; TOLL-LIKE RECEPTORS; VACCINES;

EID: 80052294992     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024147     Document Type: Article

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