Adenovirus vector-induced innate inflammatory mediators, MAPK signaling, as well as adaptive immune responses are dependent upon both TLR2 and TLR9 in vivo

Journal of Immunology

Volumn 181, Issue 3, 2008, Pages 2134-2144

  Appledorn, Daniel M ^a   Patial, Sonika ^c   McBride, Aaron ^a   Godbehere, Sarah ^a   Van Rooijen, Nico ^d   Parameswaran, Narayanan ^c   Amalfitano, Andrea ^a,b,c  

^a Michigan State University ^*  (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c MICHIGAN STATE UNIVERSITY   (United States)

^d VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; CHEMOKINE; CLODRONIC ACID; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MYELOID DIFFERENTIATION FACTOR 88; NEUTRALIZING ANTIBODY; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 9; VIRUS ANTIBODY; ANTIBODY; TLR2 PROTEIN, MOUSE; TLR9 PROTEIN, MOUSE;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; ENZYME ACTIVATION; GENE CONSTRUCT; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE GENE; IN VIVO STUDY; INFLAMMATION; INNATE IMMUNITY; KUPFFER CELL; LIVER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; TRANSGENE; ADAPTATION; ADENOVIRUS; ANIMAL; CELL CULTURE; GENE VECTOR; GENETICS; IMMUNOLOGY; MACROPHAGE; METABOLISM; MOUSE MUTANT; SIGNAL TRANSDUCTION;

ADAPTATION, PHYSIOLOGICAL; ADENOVIRIDAE; ANIMALS; ANTIBODIES; CELLS, CULTURED; CYTOKINES; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; GENETIC VECTORS; IMMUNITY, NATURAL; KUPFFER CELLS; LIVER; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MICE; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 9;

EID: 49649109923     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.181.3.2134     Document Type: Article

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