메뉴 건너뛰기




Volumn 5, Issue 3, 2010, Pages

A new adenovirus based vaccine vector expressing an Eimeria tenella derived TLR agonist improves cellular immune responses to an antigenic target

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; CD8 ANTIGEN; GAG PROTEIN; GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR AGONIST; HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN; HUMAN IMMUNODEFICIENCY VIRUS VACCINE;

EID: 77949660661     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0009579     Document Type: Article
Times cited : (33)

References (30)
  • 1
    • 59849114234 scopus 로고    scopus 로고
    • Mechanisms of HIV non-progression; robust and sustained CD4+ T-cell proliferative responses to p24 antigen correlate with control of viraemia and lack of disease progression after long-term transfusion-acquired HIV-1 infection
    • Dyer WB, Zaunders JJ, Yuan FF, Wang B, Learmont JC, et al. (2008) Mechanisms of HIV non-progression; robust and sustained CD4+ T-cell proliferative responses to p24 antigen correlate with control of viraemia and lack of disease progression after long-term transfusion-acquired HIV-1 infection. Retrovirology 5: 112.
    • (2008) Retrovirology , vol.5 , pp. 112
    • Dyer, W.B.1    Zaunders, J.J.2    Yuan, F.F.3    Wang, B.4    Learmont, J.C.5
  • 2
    • 0030665257 scopus 로고    scopus 로고
    • Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia
    • Rosenberg ES, Billingsley JM, Caliendo AM, Boswell SL, Sax PE, et al. (1997) Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia. Science 278: 1447-1450.
    • (1997) Science , vol.278 , pp. 1447-1450
    • Rosenberg, E.S.1    Billingsley, J.M.2    Caliendo, A.M.3    Boswell, S.L.4    Sax, P.E.5
  • 3
    • 49649109923 scopus 로고    scopus 로고
    • Adenovirus vector-induced innate inflammatory mediators, MAPK signaling, as well as adaptive immune responses are dependent upon both TLR2 and TLR9 in vivo
    • Appledorn DM, Patial S, McBride A, Godbehere S, Van Rooijen N, et al. (2008) Adenovirus vector-induced innate inflammatory mediators, MAPK signaling, as well as adaptive immune responses are dependent upon both TLR2 and TLR9 in vivo. J Immunol 181: 2134-2144.
    • (2008) J Immunol , vol.181 , pp. 2134-2144
    • Appledorn, D.M.1    Patial, S.2    McBride, A.3    Godbehere, S.4    Van Rooijen, N.5
  • 4
    • 33846309241 scopus 로고    scopus 로고
    • Tolllike receptor 9 triggers an innate immune response to helper-dependent adenoviral vectors
    • Cerullo V, Seiler MP, Mane V, Brunetti-Pierri N, Clarke C, et al. (2007) Tolllike receptor 9 triggers an innate immune response to helper-dependent adenoviral vectors. Mol Ther 15: 378-385.
    • (2007) Mol Ther , vol.15 , pp. 378-385
    • Cerullo, V.1    Seiler, M.P.2    Mane, V.3    Brunetti-Pierri, N.4    Clarke, C.5
  • 5
    • 71149116830 scopus 로고    scopus 로고
    • TRIF, and TRIF-interacting TLRs differentially modulate several adenovirus vector-induced immune responses
    • Appledorn DM, Patial S, Godbehere S, Parameswaran N, Amalfitano A (2009) TRIF, and TRIF-interacting TLRs differentially modulate several adenovirus vector-induced immune responses. J Innate Immun 1: 376-388.
    • (2009) J Innate Immun , vol.1 , pp. 376-388
    • Appledorn, D.M.1    Patial, S.2    Godbehere, S.3    Parameswaran, N.4    Amalfitano, A.5
  • 6
    • 38949207486 scopus 로고    scopus 로고
    • Adenovirus vector induced innate immune responses: Impact upon efficacy and toxicity in gene therapy and vaccine applications
    • Hartman ZC, Appledorn DM, Amalfitano A (2008) Adenovirus vector induced innate immune responses: Impact upon efficacy and toxicity in gene therapy and vaccine applications. Virus Res 132: 1-14.
    • (2008) Virus Res , vol.132 , pp. 1-14
    • Hartman, Z.C.1    Appledorn, D.M.2    Amalfitano, A.3
  • 7
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • Iwasaki A, Medzhitov R (2004) Toll-like receptor control of the adaptive immune responses. Nat Immunol 5: 987-995.
    • (2004) Nat Immunol , vol.5 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 8
    • 33847183077 scopus 로고    scopus 로고
    • Cooperation of Toll-like receptor signals in innate immune defence
    • Trinchieri G, Sher A (2007) Cooperation of Toll-like receptor signals in innate immune defence. Nat Rev Immunol 7: 179-190.
    • (2007) Nat Rev Immunol , vol.7 , pp. 179-190
    • Trinchieri, G.1    Sher, A.2
  • 9
    • 42449123606 scopus 로고    scopus 로고
    • Natural killer cell-directed therapies: Moving from unexpected results to successful strategies
    • Terme M, Ullrich E, Delahaye NF, Chaput N, Zitvogel L (2008) Natural killer cell-directed therapies: moving from unexpected results to successful strategies. Nat Immunol 9: 486-494.
    • (2008) Nat Immunol , vol.9 , pp. 486-494
    • Terme, M.1    Ullrich, E.2    Delahaye, N.F.3    Chaput, N.4    Zitvogel, L.5
  • 10
    • 63449126998 scopus 로고    scopus 로고
    • Toll-like receptors and their role in carcinogenesis and anti-tumor treatment
    • Wolska A, Lech-Maranda E, Robak T (2009) Toll-like receptors and their role in carcinogenesis and anti-tumor treatment. Cell Mol Biol Lett 14: 248-272.
    • (2009) Cell Mol Biol Lett , vol.14 , pp. 248-272
    • Wolska, A.1    Lech-Maranda, E.2    Robak, T.3
  • 11
    • 20044387389 scopus 로고    scopus 로고
    • Protein from intestinal Eimeria protozoan stimulates IL-12 release from dendritic cells, exhibits antitumor properties in vivo and is correlated with low intestinal tumorigenicity
    • Rosenberg B, Juckett DA, Aylsworth CF, Dimitrov NV, Ho SC, et al. (2005) Protein from intestinal Eimeria protozoan stimulates IL-12 release from dendritic cells, exhibits antitumor properties in vivo and is correlated with low intestinal tumorigenicity. Int J Cancer 114: 756-765.
    • (2005) Int J Cancer , vol.114 , pp. 756-765
    • Rosenberg, B.1    Juckett, D.A.2    Aylsworth, C.F.3    Dimitrov, N.V.4    Ho, S.C.5
  • 12
    • 20644433342 scopus 로고    scopus 로고
    • TLR11 activation of dendritic cells by a protozoan profilin-like protein
    • Yarovinsky F, Zhang D, Andersen JF, Bannenberg GL, Serhan CN, et al. (2005) TLR11 activation of dendritic cells by a protozoan profilin-like protein. Science 308: 1626-1629.
    • (2005) Science , vol.308 , pp. 1626-1629
    • Yarovinsky, F.1    Zhang, D.2    Andersen, J.F.3    Bannenberg, G.L.4    Serhan, C.N.5
  • 13
    • 49649097700 scopus 로고    scopus 로고
    • Phase I study and preliminary pharmacology of the novel innate immune modulator rBBX-01 in gynecologic cancers
    • Rader JS, Aylsworth CF, Juckett DA, Mutch DG, Powell MA, et al. (2008) Phase I study and preliminary pharmacology of the novel innate immune modulator rBBX-01 in gynecologic cancers. Clin Cancer Res 14: 3089-3097.
    • (2008) Clin Cancer Res , vol.14 , pp. 3089-3097
    • Rader, J.S.1    Aylsworth, C.F.2    Juckett, D.A.3    Mutch, D.G.4    Powell, M.A.5
  • 14
    • 61849179808 scopus 로고    scopus 로고
    • Protective immunity against Toxoplasma challenge in mice by coadministration of T. gondii antigens and Eimeria profilin-like protein as an adjuvant
    • Hedhli D, Dimier-Poisson I, Judge JW, Rosenberg B, Mevelec MN (2009) Protective immunity against Toxoplasma challenge in mice by coadministration of T. gondii antigens and Eimeria profilin-like protein as an adjuvant. Vaccine 27: 2274-2281.
    • (2009) Vaccine , vol.27 , pp. 2274-2281
    • Hedhli, D.1    Dimier-Poisson, I.2    Judge, J.W.3    Rosenberg, B.4    Mevelec, M.N.5
  • 15
    • 33744482559 scopus 로고    scopus 로고
    • Recombinant Eimeria protozoan protein elicits resistance to acute phlebovirus infection in mice but not hamsters
    • Gowen BB, Smee DF, Wong MH, Judge JW, Jung KH, et al. (2006) Recombinant Eimeria protozoan protein elicits resistance to acute phlebovirus infection in mice but not hamsters. Antimicrob Agents Chemother 50: 2023-2029.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 2023-2029
    • Gowen, B.B.1    Smee, D.F.2    Wong, M.H.3    Judge, J.W.4    Jung, K.H.5
  • 16
    • 1642277986 scopus 로고    scopus 로고
    • NF-kappaB- and c-Jun-dependent regulation of human cytomegalovirus immediate-early gene enhancer/promoter in response to lipopolysaccharide and bacterial CpG-oligodeoxynucleotides in macrophage cell line RAW 264.7
    • Lee Y, Sohn WJ, Kim DS, Kwon HJ (2004) NF-kappaB- and c-Jun-dependent regulation of human cytomegalovirus immediate-early gene enhancer/promoter in response to lipopolysaccharide and bacterial CpG-oligodeoxynucleotides in macrophage cell line RAW 264.7. Eur J Biochem 271: 1094-1105.
    • (2004) Eur J Biochem , vol.271 , pp. 1094-1105
    • Lee, Y.1    Sohn, W.J.2    Kim, D.S.3    Kwon, H.J.4
  • 17
    • 45749110171 scopus 로고    scopus 로고
    • A critical role for type I IFN-dependent NK cell activation in innate immune elimination of adenoviral vectors in vivo
    • Zhu J, Huang X, Yang Y (2008) A critical role for type I IFN-dependent NK cell activation in innate immune elimination of adenoviral vectors in vivo. Mol Ther 16: 1300-1307.
    • (2008) Mol Ther , vol.16 , pp. 1300-1307
    • Zhu, J.1    Huang, X.2    Yang, Y.3
  • 18
    • 44449151187 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells are activated by Toxoplasma gondii to present antigen and produce cytokines
    • Pepper M, Dzierszinski F, Wilson E, Tait E, Fang Q, et al. (2008) Plasmacytoid dendritic cells are activated by Toxoplasma gondii to present antigen and produce cytokines. J Immunol 180: 6229-6236.
    • (2008) J Immunol , vol.180 , pp. 6229-6236
    • Pepper, M.1    Dzierszinski, F.2    Wilson, E.3    Tait, E.4    Fang, Q.5
  • 20
    • 34548284487 scopus 로고    scopus 로고
    • Paradoxical enhancement of CD8 T cell-dependent anti-tumor protection despite reduced CD8 T cell responses with addition of a TLR9 agonist to a tumor vaccine
    • Karan D, Krieg AM, Lubaroff DM (2007) Paradoxical enhancement of CD8 T cell-dependent anti-tumor protection despite reduced CD8 T cell responses with addition of a TLR9 agonist to a tumor vaccine. Int J Cancer 121: 1520-1528.
    • (2007) Int J Cancer , vol.121 , pp. 1520-1528
    • Karan, D.1    Krieg, A.M.2    Lubaroff, D.M.3
  • 21
    • 58149267963 scopus 로고    scopus 로고
    • Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys
    • Liu J, O'Brien KL, Lynch DM, Simmons NL, La Porte A, et al. (2009) Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys. Nature 457: 87-91.
    • (2009) Nature , vol.457 , pp. 87-91
    • Liu, J.1    O'Brien, K.L.2    Lynch, D.M.3    Simmons, N.L.4    La Porte, A.5
  • 22
    • 0038664390 scopus 로고    scopus 로고
    • Comparative immunogenicity in rhesus monkeys of DNA plasmid, recombinant vaccinia virus, and replication-defective adenovirus vectors expressing a human immunodeficiency virus type 1 gag gene
    • Casimiro DR, Chen L, Fu TM, Evans RK, Caulfield MJ, et al. (2003) Comparative immunogenicity in rhesus monkeys of DNA plasmid, recombinant vaccinia virus, and replication-defective adenovirus vectors expressing a human immunodeficiency virus type 1 gag gene. J Virol 77: 6305-6313.
    • (2003) J Virol , vol.77 , pp. 6305-6313
    • Casimiro, D.R.1    Chen, L.2    Fu, T.M.3    Evans, R.K.4    Caulfield, M.J.5
  • 23
    • 0037787982 scopus 로고    scopus 로고
    • Activation of natural killer T cells by alpha-galactosylceramide rapidly induces the full maturation of dendritic cells in vivo and thereby acts as an adjuvant for combined CD4 and CD8 T cell immunity to a coadministered protein
    • Fujii S, Shimizu K, Smith C, Bonifaz L, Steinman RM (2003) Activation of natural killer T cells by alpha-galactosylceramide rapidly induces the full maturation of dendritic cells in vivo and thereby acts as an adjuvant for combined CD4 and CD8 T cell immunity to a coadministered protein. J Exp Med 198: 267-279.
    • (2003) J Exp Med , vol.198 , pp. 267-279
    • Fujii, S.1    Shimizu, K.2    Smith, C.3    Bonifaz, L.4    Steinman, R.M.5
  • 24
    • 33947111517 scopus 로고    scopus 로고
    • Helper roles of NK and CD8+ T cells in the induction of tumor immunity. Polarized dendritic cells as cancer vaccines
    • Kalinski P, Nakamura Y, Watchmaker P, Giermasz A, Muthuswamy R, et al. (2006) Helper roles of NK and CD8+ T cells in the induction of tumor immunity. Polarized dendritic cells as cancer vaccines. Immunol Res 36: 137-146.
    • (2006) Immunol Res , vol.36 , pp. 137-146
    • Kalinski, P.1    Nakamura, Y.2    Watchmaker, P.3    Giermasz, A.4    Muthuswamy, R.5
  • 25
    • 44849140020 scopus 로고    scopus 로고
    • Wild-type adenoviruses from groups A-F evoke unique innate immune responses, of which HAd3 and SAd23 are partially complement dependent
    • Appledorn DM, Kiang A, McBride A, Jiang H, Seregin S, et al. (2008)Wild-type adenoviruses from groups A-F evoke unique innate immune responses, of which HAd3 and SAd23 are partially complement dependent. Gene Ther 15: 885-901.
    • (2008) Gene Ther , vol.15 , pp. 885-901
    • Appledorn, D.M.1    Kiang, A.2    McBride, A.3    Jiang, H.4    Seregin, S.5
  • 26
    • 56649105122 scopus 로고    scopus 로고
    • Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): A double-blind, randomised, placebo-controlled, test-of-concept trial
    • Buchbinder SP, Mehrotra DV, Duerr A, Fitzgerald DW, Mogg R, et al. (2008) Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial. Lancet 372: 1881-1893.
    • (2008) Lancet , vol.372 , pp. 1881-1893
    • Buchbinder, S.P.1    Mehrotra, D.V.2    Duerr, A.3    Fitzgerald, D.W.4    Mogg, R.5
  • 27
    • 73949119632 scopus 로고    scopus 로고
    • Adenovirus vector vaccination induces expansion of memory CD4 T cells with a mucosal homing phenotype that are readily susceptible to HIV-1
    • Benlahrech A, Harris J, Meiser A, Papagatsias T, Hornig J, et al. (2009) Adenovirus vector vaccination induces expansion of memory CD4 T cells with a mucosal homing phenotype that are readily susceptible to HIV-1. Proc Natl Acad Sci U S A 106: 19940-19945.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 19940-19945
    • Benlahrech, A.1    Harris, J.2    Meiser, A.3    Papagatsias, T.4    Hornig, J.5
  • 28
    • 68349130410 scopus 로고    scopus 로고
    • Baseline Ad5 serostatus does not predict Ad5 HIV vaccine-induced expansion of adenovirus-specific CD4+ T cells
    • Hutnick NA, Carnathan DG, Dubey SA, Makedonas G, Cox KS, et al. (2009) Baseline Ad5 serostatus does not predict Ad5 HIV vaccine-induced expansion of adenovirus-specific CD4+ T cells. Nat Med 15: 876-878.
    • (2009) Nat Med , vol.15 , pp. 876-878
    • Hutnick, N.A.1    Carnathan, D.G.2    Dubey, S.A.3    Makedonas, G.4    Cox, K.S.5
  • 30
    • 0035988785 scopus 로고    scopus 로고
    • Construction of first-generation adenoviral vectors
    • Ng P, Graham FL (2002) Construction of first-generation adenoviral vectors. Methods Mol Med 69: 389-414.
    • (2002) Methods Mol Med , vol.69 , pp. 389-414
    • Ng, P.1    Graham, F.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.