Modifying matrix micro-environmental pH to achieve sustained drug release from highly laminating alginate matrices

European Journal of Pharmaceutical Sciences

Volumn 33, Issue 4-5, 2008, Pages 361-370

  Ching, Ai Ling ^a   Liew, Celine Valeria ^a   Chan, Lai Wah ^a   Heng, Paul Wan Sia ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Lamination; Micro environmental pH; pH sensitive polymer; Sustained release

Indexed keywords

ALGINIC ACID; BICARBONATE; CARBON DIOXIDE;

ARTICLE; CONTROLLED STUDY; DRUG DIFFUSION; PRIORITY JOURNAL; PROTON TRANSPORT; STOMACH PH; SUSTAINED DRUG RELEASE;

ALGINATES; CHLORPHENIRAMINE; DRUG COMPOUNDING; DRUG STABILITY; GLUCURONIC ACID; HEXURONIC ACIDS; HYDROGEN-ION CONCENTRATION; SOLUBILITY; TABLETS, ENTERIC-COATED;

EID: 41349096207     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2008.01.007     Document Type: Article

References (27)

1. In: Baden W. (Ed). Chemicals Reagents (2000), Merck KGaA, Darmstadt
2. Chakrabarti S., and Southard M.Z. Control of poorly soluble drug dissolution in conditions simulating the gastrointestinal tract flow. 2. Cocompression of drugs with buffers. J. Pharm. Sci. 86 (1997) 465-469
3. Chan L.W., Ching A.L., Heng P.W.S., and Liew C.V. Mechanistic study on hydration and drug release behavior of sodium alginate compacts. Drug Dev. Ind. Pharm. 33 6 (2007) 667-676
4. Charlton B., and Newton J.M. Application of gamma-ray attenuation to the determination of density distributions within compacted powders. Powder Technol. 41 (1985) 123-134
5. Efentakis M., and Buckton G. The effect of erosion and swelling on the dissolution of theophylline from low and high viscosity sodium alginate matrices. Pharm. Dev. Technol. 7 (2002) 69-77
6. Eiliazadeh B., Briscoe B.J., Sheng Y., and Pitt K. Investigating density distribution for tablets of different geometry during the compaction of pharmaceuticals. Particul. Sci. Technol. 21 (2003) 303-316
7. Haug A. Composition and properties of alginates. Thesis (1964), Norwegian Institute of Technology, Trondheim
8. Higuchi T. Rate of release of medicaments from ointment bases containing drugs in suspensions. J. Pharm. Sci. 50 (1961) 874-875
9. Higuchi T. Mechanisms of sustained-action medication: theoretical analysis of rate of release of solid drugs dispersed in solid matrices. J. Pharm. Sci. 52 (1963) 1145-1149
10. Kadiri M.S., Michrafy A., and Dodds J.A. Pharmaceutical powders compaction: experimental and numerical analysis of the density distribution. Powder Technol. 157 (2005) 176-182
11. Kavanagh N., and Corrigan O.I. Swelling and erosion properties of hydroxypropylmethylcellulose (Hypromellose) matrices-influence of agitation rate and dissolution medium composition. Int. J. Pharm. 279 (2004) 141-152
12. Lide, D.R. (Ed.), 2006. CRC Handbook of Chemistry and Physics, Internet Version 2006, Taylor and Francis, Boca Raton, FL. http://www.hbcpnetbase.com.
13. Liew C.V., Chan L.W., Ching A.L., and Heng P.W.S. Evaluation of sodium alginate as drug release modifier in matrix tablets. Int. J. Pharm. 309 (2006) 25-37
14. Malamataris S., Hatjichristos Th., and Rees J.E. Apparent compressive elastic modulus and strength isotropy of compacts formed from binary powder mixes. Int. J. Pharm. 141 (1996) 101-108
15. Moe D.V., and Rippie E.G. Nondestructive viscoelastic analysis of anisotropy in compressed tablets. J. Pharm. Sci. 86 (1997) 26-32
16. In: Moffat A.C., Jackson J.V., Moss M.S., and Bishop B. (Eds). Clarke's isolation and identification of drugs in pharmaceuticals, body fluids, and post-mortem material (1986), Pharmaceutical Press, London
17. Moreno-Villoslada I., Oyarzún F., Miranda V., Hess S., and Rivas B.L. Binding of chlorpheniramine maleate to pharmacologically important alginic acid, carboxymethylcellulose, κ-carageenan, and ι-carrageenan as studied by diafiltration. J. Appl. Polym. Sci. 98 (2005) 598-602
18. Mullarney M.P., and Hancock B.C. Mechanical property anisotropy of pharmaceutical excipient compacts. Int. J. Pharm. 314 (2006) 9-14
19. Pillay V., and Fassihi R. Electrolyte-induced compositional heterogeneity: a novel approach for rate-controlled oral drug delivery. J. Pharm. Sci. 88 (1999) 1140-1148
20. Ritger P.L., and Peppas N.A. A simple equation for description of solute release. I. Fickian and non-Fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs. J. Control. Rel. 5 (1987) 23-36
21. Ritger P.L., and Peppas N.A. A simple equation for description of solute release. I. Fickian and anomalous release from swellable devices. J. Control. Rel. 5 (1987) 37-42
22. Siepe S., Herrmann W., Borchert H.-H., Lueckel B., Kramer A., Ries A., and Gurny R. Microenvironmental pH and microviscosity inside pH-controlled matrix tablets: an EPR imaging study. J. Control. Rel. 112 (2006) 72-78
23. Streubel A., Siepmann J., Dashevsky A., and Bodmeier R. pH-independent release of a weakly basic drug from water-insoluble and soluble matrix tablets. J. Control. Rel. 67 (2000) 101-110
24. Tatavarti A.S., and Hoag S.W. Microenvironmental pH modulation based release enhancement of a weakly basic drug from hydrophilic matrices. J. Pharm. Sci. 95 (2006) 1459-1468
25. The United States Pharmacopeia, 2002. Chapters <711> and <724>, United States Pharmacopeial Convention, Inc., Rockville, MD.
26. Varma M.V.S., Kaushal A.M., and Garg S. Influence of micro-environmental pH on the gel layer behavior and release of a basic drug from various hydrophilic matrices. J. Control. Rel. 103 (2005) 499-510
27. Wikipedia contributors, in press. Acid dissociation constant. In: Wikipedia, The Free Encyclopedia. http://en.wikipedia.org/w/index.php?title=Acid_dissociation_constant&oldid=192367637 (accessed February 18, 2008).