메뉴 건너뛰기




Volumn 192, Issue , 2011, Pages 37-53

Transcription factor Phox2 upregulates expression of norepinephrine transporter and dopamine β-hydroxylase in adult rat brains

Author keywords

Dopamine hydroxylase; Locus coeruleus; Neurogenesis; Noradrenergic neurons; Norepinephrine transporter; Phox2

Indexed keywords

DOPAMINE BETA MONOOXYGENASE; MESSENGER RNA; NORADRENALIN TRANSPORTER; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PHOX2A; TRANSCRIPTION FACTOR PHOX2B; UNCLASSIFIED DRUG;

EID: 80052268550     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.07.005     Document Type: Article
Times cited : (20)

References (68)
  • 1
    • 0033819080 scopus 로고    scopus 로고
    • Paired-like homeodomain proteins Phox2a/Arix and Phox2b/NBPhox have similar genetic organization and independently regulate dopamine beta-hydroxylase gene transcription
    • Adachi M., Browne D., Lewis E.J. Paired-like homeodomain proteins Phox2a/Arix and Phox2b/NBPhox have similar genetic organization and independently regulate dopamine beta-hydroxylase gene transcription. DNA Cell Biol 2000, 19:539-554.
    • (2000) DNA Cell Biol , vol.19 , pp. 539-554
    • Adachi, M.1    Browne, D.2    Lewis, E.J.3
  • 2
    • 0037151035 scopus 로고    scopus 로고
    • The paired-like homeodomain protein, Arix, mediates protein kinase A-stimulated dopamine beta-hydroxylase gene transcription through its phosphorylation status
    • Adachi M., Lewis E.J. The paired-like homeodomain protein, Arix, mediates protein kinase A-stimulated dopamine beta-hydroxylase gene transcription through its phosphorylation status. J Biol Chem 2002, 277:22915-22924.
    • (2002) J Biol Chem , vol.277 , pp. 22915-22924
    • Adachi, M.1    Lewis, E.J.2
  • 3
    • 0036897235 scopus 로고    scopus 로고
    • Multicistronic lentiviral vector-mediated striatal gene transfer of aromatic l-amino acid decarboxylase, tyrosine hydroxylase, and GTP cyclohydrolase I induces sustained transgene expression, dopamine production, and functional improvement in a rat model of Parkinson's disease
    • Azzouz M., Martin-Rendon E., Barber R.D., Mitrophanous K.A., Carter E.E., Rohll J.B., Kingsman S.M., Kingsman A.J., Mazarakis N.D. Multicistronic lentiviral vector-mediated striatal gene transfer of aromatic l-amino acid decarboxylase, tyrosine hydroxylase, and GTP cyclohydrolase I induces sustained transgene expression, dopamine production, and functional improvement in a rat model of Parkinson's disease. J Neurosci 2002, 22:10302-10312.
    • (2002) J Neurosci , vol.22 , pp. 10302-10312
    • Azzouz, M.1    Martin-Rendon, E.2    Barber, R.D.3    Mitrophanous, K.A.4    Carter, E.E.5    Rohll, J.B.6    Kingsman, S.M.7    Kingsman, A.J.8    Mazarakis, N.D.9
  • 4
    • 0000358207 scopus 로고
    • Norepinephrine and serotonin transporters. Moleculartargets of antidepressant drugs
    • Raven, New York, F. Bloom, D. Kupfer (Eds.)
    • Barker E., Blakely R. Norepinephrine and serotonin transporters. Moleculartargets of antidepressant drugs. Psychopharmacology. A fourth generation of progress 1995, 321-333. Raven, New York. F. Bloom, D. Kupfer (Eds.).
    • (1995) Psychopharmacology. A fourth generation of progress , pp. 321-333
    • Barker, E.1    Blakely, R.2
  • 6
    • 77952112986 scopus 로고    scopus 로고
    • Distribution and phenotype of Phox2a-containing neurons in the adult Sprague-Dawley rat
    • Card J.P., Lois J., Sved A.F. Distribution and phenotype of Phox2a-containing neurons in the adult Sprague-Dawley rat. J Comp Neurol 2010, 518:2202-2220.
    • (2010) J Comp Neurol , vol.518 , pp. 2202-2220
    • Card, J.P.1    Lois, J.2    Sved, A.F.3
  • 7
    • 0037209052 scopus 로고    scopus 로고
    • Viral-mediated gene transfer to study the behavioral correlates of CREB function in the nucleus accumbenes of rats
    • Humana Press, Totowa, NJ, J.Q. Wang (Ed.)
    • Carlezon W.A., Neve R.L. Viral-mediated gene transfer to study the behavioral correlates of CREB function in the nucleus accumbenes of rats. Methods in molecular medicine, 79: drugs of abuse: neurological reviews and protocols 2003, 331-350. Humana Press, Totowa, NJ. J.Q. Wang (Ed.).
    • (2003) Methods in molecular medicine, 79: drugs of abuse: neurological reviews and protocols , pp. 331-350
    • Carlezon, W.A.1    Neve, R.L.2
  • 9
  • 10
    • 0024436073 scopus 로고
    • Quantitation of catecholamine neurons in the locus coeruleus in human brains of normal young and older adults and in depression
    • Chan-Palay V., Asan E. Quantitation of catecholamine neurons in the locus coeruleus in human brains of normal young and older adults and in depression. J Comp Neurol 1989, 287:357-372.
    • (1989) J Comp Neurol , vol.287 , pp. 357-372
    • Chan-Palay, V.1    Asan, E.2
  • 11
    • 33745014606 scopus 로고    scopus 로고
    • Hippocampal cell proliferation regulation by repeated stress and antidepressants
    • Chen H., Pandey G.N., Dwivedi Y. Hippocampal cell proliferation regulation by repeated stress and antidepressants. Neuroreport 2006, 17:863-867.
    • (2006) Neuroreport , vol.17 , pp. 863-867
    • Chen, H.1    Pandey, G.N.2    Dwivedi, Y.3
  • 12
    • 0032512115 scopus 로고    scopus 로고
    • Noradrenaline transporter expression in the pons and medulla oblongata of the rat: localisation to noradrenergic and some C1 adrenergic neurones
    • Comer A.M., Qi J., Christie D.L., Gibbons H.M., Lipski J. Noradrenaline transporter expression in the pons and medulla oblongata of the rat: localisation to noradrenergic and some C1 adrenergic neurones. Brain Res Mol Brain Res 1998, 62:65-76.
    • (1998) Brain Res Mol Brain Res , vol.62 , pp. 65-76
    • Comer, A.M.1    Qi, J.2    Christie, D.L.3    Gibbons, H.M.4    Lipski, J.5
  • 13
    • 78650180926 scopus 로고    scopus 로고
    • Ongoing roles of Phox2 homeodomain transcription factors during neuronal differentiation
    • Coppola E., d'Autréaux F., Rijli F.M., Brunet J.F. Ongoing roles of Phox2 homeodomain transcription factors during neuronal differentiation. Development 2010, 137:4211-4220.
    • (2010) Development , vol.137 , pp. 4211-4220
    • Coppola, E.1    d'Autréaux, F.2    Rijli, F.M.3    Brunet, J.F.4
  • 14
    • 29244442739 scopus 로고    scopus 로고
    • Reciprocal gene replacements reveal unique functions for Phox2 genes during neural differentiation
    • Coppola E., Pattyn A., Guthrie S.C., Goridis C., Studer M. Reciprocal gene replacements reveal unique functions for Phox2 genes during neural differentiation. EMBO J 2005, 24:4392-4403.
    • (2005) EMBO J , vol.24 , pp. 4392-4403
    • Coppola, E.1    Pattyn, A.2    Guthrie, S.C.3    Goridis, C.4    Studer, M.5
  • 17
    • 68949202508 scopus 로고    scopus 로고
    • Effects of transcription factors Phox2 on expression of norepinephrine transporter and dopamine beta-hydroxylase in SK-N-BE(2)C cells
    • Fan Y., Huang J., Kieran N., Zhu M.Y. Effects of transcription factors Phox2 on expression of norepinephrine transporter and dopamine beta-hydroxylase in SK-N-BE(2)C cells. J Neurochem 2009, 110:1502-1513.
    • (2009) J Neurochem , vol.110 , pp. 1502-1513
    • Fan, Y.1    Huang, J.2    Kieran, N.3    Zhu, M.Y.4
  • 20
    • 0028213815 scopus 로고
    • Disproportionate loss of noradrenergic and cholinergic neurons as cause of depression in Alzheimer's disease-a hypothesis
    • Forstl H., Levy R., Burns A., Luthert P., Cairns N. Disproportionate loss of noradrenergic and cholinergic neurons as cause of depression in Alzheimer's disease-a hypothesis. Pharmacopsychiatry 1994, 27:11-15.
    • (1994) Pharmacopsychiatry , vol.27 , pp. 11-15
    • Forstl, H.1    Levy, R.2    Burns, A.3    Luthert, P.4    Cairns, N.5
  • 21
    • 0036634851 scopus 로고    scopus 로고
    • Specification of catecholaminergic and serotonergic neurons
    • Goridis C., Rohrer H. Specification of catecholaminergic and serotonergic neurons. Nat Rev Neurosci 2002, 3:531-541.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 531-541
    • Goridis, C.1    Rohrer, H.2
  • 23
    • 0031910150 scopus 로고    scopus 로고
    • Control of noradrenergic differentiation and Phox2a expression by MASH1 in the central and peripheral nervous system
    • Hirsch M.R., Tiveron M.C., Guillemot F., Brunet J.F., Goridis C. Control of noradrenergic differentiation and Phox2a expression by MASH1 in the central and peripheral nervous system. Development 1998, 125:599-608.
    • (1998) Development , vol.125 , pp. 599-608
    • Hirsch, M.R.1    Tiveron, M.C.2    Guillemot, F.3    Brunet, J.F.4    Goridis, C.5
  • 24
    • 11144264102 scopus 로고    scopus 로고
    • Mechanisms and perspectives on differentiation of autonomic neurons
    • Howard M.J. Mechanisms and perspectives on differentiation of autonomic neurons. Dev Biol 2005, 277:271-286.
    • (2005) Dev Biol , vol.277 , pp. 271-286
    • Howard, M.J.1
  • 25
    • 33748972775 scopus 로고    scopus 로고
    • The sympathoadrenal cell lineage: specification, diversification, and new perspectives
    • Huber K. The sympathoadrenal cell lineage: specification, diversification, and new perspectives. Dev Biol 2006, 298:335-343.
    • (2006) Dev Biol , vol.298 , pp. 335-343
    • Huber, K.1
  • 26
    • 0034006816 scopus 로고    scopus 로고
    • Age-dependent changes in projections from locus coeruleus to hippocampus dentate gyrus and frontal cortex
    • Ishida Y., Shirokawa T., Miyaishi O., Komatsu Y., Isobe K. Age-dependent changes in projections from locus coeruleus to hippocampus dentate gyrus and frontal cortex. Eur J Neurosci 2000, 12:1263-1270.
    • (2000) Eur J Neurosci , vol.12 , pp. 1263-1270
    • Ishida, Y.1    Shirokawa, T.2    Miyaishi, O.3    Komatsu, Y.4    Isobe, K.5
  • 29
    • 0003093246 scopus 로고
    • Dopamine-beta-hydroxylase
    • Kaufman S., Friedman S. Dopamine-beta-hydroxylase. Pharmacol Rev 1965, 17:71-100.
    • (1965) Pharmacol Rev , vol.17 , pp. 71-100
    • Kaufman, S.1    Friedman, S.2
  • 30
    • 0036551206 scopus 로고    scopus 로고
    • A proximal promoter domain containing a homeodomain-binding core motif interacts with multiple transcription factors, including HoxA5 and Phox2 proteins, and critically regulates cell type-specific transcription of the human norepinephrine transporter gene
    • Kim C.H., Hwang D.Y., Park J.J., Kim K.S. A proximal promoter domain containing a homeodomain-binding core motif interacts with multiple transcription factors, including HoxA5 and Phox2 proteins, and critically regulates cell type-specific transcription of the human norepinephrine transporter gene. J Neurosci 2002, 22:2579-2589.
    • (2002) J Neurosci , vol.22 , pp. 2579-2589
    • Kim, C.H.1    Hwang, D.Y.2    Park, J.J.3    Kim, K.S.4
  • 31
    • 0033525881 scopus 로고    scopus 로고
    • A previously undescribed intron and extensive 5' upstream sequence, but not Phox2a-mediated transactivation, are necessary for high level cell type-specific expression of the human norepinephrine transporter gene
    • Kim C.H., Kim H.S., Cubells J.F., Kim K.S. A previously undescribed intron and extensive 5' upstream sequence, but not Phox2a-mediated transactivation, are necessary for high level cell type-specific expression of the human norepinephrine transporter gene. J Biol Chem 1999, 274:6507-6518.
    • (1999) J Biol Chem , vol.274 , pp. 6507-6518
    • Kim, C.H.1    Kim, H.S.2    Cubells, J.F.3    Kim, K.S.4
  • 32
    • 0032531711 scopus 로고    scopus 로고
    • Noradrenergic-specific transcription of the dopamine beta-hydroxylase gene requires synergy of multiple cis-acting elements including at least two Phox2a-binding sites
    • Kim H.S., Seo H., Yang C., Brunet J.F., Kim K.S. Noradrenergic-specific transcription of the dopamine beta-hydroxylase gene requires synergy of multiple cis-acting elements including at least two Phox2a-binding sites. J Neurosci 1998, 18:8247-8260.
    • (1998) J Neurosci , vol.18 , pp. 8247-8260
    • Kim, H.S.1    Seo, H.2    Yang, C.3    Brunet, J.F.4    Kim, K.S.5
  • 33
    • 0026653322 scopus 로고
    • Noradrenaline depletion blocks behavioral sparing and alters cortical morphogenesis after neonatal frontal cortex damage in rats
    • Kolb B., Sutherland R.J. Noradrenaline depletion blocks behavioral sparing and alters cortical morphogenesis after neonatal frontal cortex damage in rats. J Neurosci 1992, 12:2321-2330.
    • (1992) J Neurosci , vol.12 , pp. 2321-2330
    • Kolb, B.1    Sutherland, R.J.2
  • 34
    • 0029863342 scopus 로고    scopus 로고
    • Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation
    • Kuhn H.G., Dickinson-Anson H., Gage F.H. Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J Neurosci 1996, 16:2027-2033.
    • (1996) J Neurosci , vol.16 , pp. 2027-2033
    • Kuhn, H.G.1    Dickinson-Anson, H.2    Gage, F.H.3
  • 35
    • 0036833778 scopus 로고    scopus 로고
    • Depletion of norepinephrine decreases the proliferation, but does not influence the survival and differentiation, of granule cell progenitors in the adult rat hippocampus
    • Kulkarni V.A., Jha S., Vaidya V.A. Depletion of norepinephrine decreases the proliferation, but does not influence the survival and differentiation, of granule cell progenitors in the adult rat hippocampus. Eur J Neurosci 2002, 16:2008-2012.
    • (2002) Eur J Neurosci , vol.16 , pp. 2008-2012
    • Kulkarni, V.A.1    Jha, S.2    Vaidya, V.A.3
  • 36
    • 0033119681 scopus 로고    scopus 로고
    • Specification of neurotransmitter identity by Phox2 proteins in neural crest stem cells
    • Lo L., Morin X., Brunet J.F., Anderson D.J. Specification of neurotransmitter identity by Phox2 proteins in neural crest stem cells. Neuron 1999, 22:693-705.
    • (1999) Neuron , vol.22 , pp. 693-705
    • Lo, L.1    Morin, X.2    Brunet, J.F.3    Anderson, D.J.4
  • 37
    • 0036468677 scopus 로고    scopus 로고
    • Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors
    • Lois C., Hong E.J., Pease S., Brown E.J., Baltimore D. Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors. Science 2002, 295:868-872.
    • (2002) Science , vol.295 , pp. 868-872
    • Lois, C.1    Hong, E.J.2    Pease, S.3    Brown, E.J.4    Baltimore, D.5
  • 38
    • 0027933179 scopus 로고
    • Cell-type-specific expression of catecholamine transporters in the rat brain
    • Lorang D., Amara S.G., Simerly R.B. Cell-type-specific expression of catecholamine transporters in the rat brain. J Neurosci 1994, 14:4903-4914.
    • (1994) J Neurosci , vol.14 , pp. 4903-4914
    • Lorang, D.1    Amara, S.G.2    Simerly, R.B.3
  • 39
    • 0034671366 scopus 로고    scopus 로고
    • Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus
    • Malberg J.E., Eisch A.J., Nestler E.J., Duman R.S. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J Neurosci 2000, 20:9104-9110.
    • (2000) J Neurosci , vol.20 , pp. 9104-9110
    • Malberg, J.E.1    Eisch, A.J.2    Nestler, E.J.3    Duman, R.S.4
  • 40
    • 33645316100 scopus 로고    scopus 로고
    • The norepinephrine transporter and its regulation
    • Mandela P., Ordway G.A. The norepinephrine transporter and its regulation. J Neurochem 2006, 97:310-333.
    • (2006) J Neurochem , vol.97 , pp. 310-333
    • Mandela, P.1    Ordway, G.A.2
  • 42
    • 0030936255 scopus 로고    scopus 로고
    • Defects in sensory and autonomic ganglia and absence of locus coeruleus in mice deficient for the homeobox gene Phox2a
    • Morin X., Cremer H., Hirsch M.R., Kapur R.P., Goridis C., Brunet J.F. Defects in sensory and autonomic ganglia and absence of locus coeruleus in mice deficient for the homeobox gene Phox2a. Neuron 1997, 18:411-423.
    • (1997) Neuron , vol.18 , pp. 411-423
    • Morin, X.1    Cremer, H.2    Hirsch, M.R.3    Kapur, R.P.4    Goridis, C.5    Brunet, J.F.6
  • 43
    • 38449091547 scopus 로고    scopus 로고
    • Biochemistry of postmortem brains in Parkinson's disease: historical overview and future prospects
    • Nagatsu T., Sawada M. Biochemistry of postmortem brains in Parkinson's disease: historical overview and future prospects. J Neural Transm Suppl 2007, 113-120.
    • (2007) J Neural Transm Suppl , pp. 113-120
    • Nagatsu, T.1    Sawada, M.2
  • 44
    • 0029993858 scopus 로고    scopus 로고
    • Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector
    • Naldini L., Blömer U., Gage F.H., Trono D., Verma I.M. Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc Natl Acad Sci U S A 1996, 93:11382-11388.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 11382-11388
    • Naldini, L.1    Blömer, U.2    Gage, F.H.3    Trono, D.4    Verma, I.M.5
  • 45
    • 0034034865 scopus 로고    scopus 로고
    • Specification of the central noradrenergic phenotype by the homeobox gene Phox2b
    • Pattyn A., Goridis C., Brunet J.F. Specification of the central noradrenergic phenotype by the homeobox gene Phox2b. Mol Cell Neurosci 2000, 15:235-243.
    • (2000) Mol Cell Neurosci , vol.15 , pp. 235-243
    • Pattyn, A.1    Goridis, C.2    Brunet, J.F.3
  • 46
    • 0030731439 scopus 로고    scopus 로고
    • Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis
    • Pattyn A., Morin X., Cremer H., Goridis C., Brunet J.F. Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis. Development 1997, 124:4065-4075.
    • (1997) Development , vol.124 , pp. 4065-4075
    • Pattyn, A.1    Morin, X.2    Cremer, H.3    Goridis, C.4    Brunet, J.F.5
  • 47
    • 0033609337 scopus 로고    scopus 로고
    • The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives
    • Pattyn A., Morin X., Cremer H., Goridis C., Brunet J.F. The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives. Nature 1999, 399:366-370.
    • (1999) Nature , vol.399 , pp. 366-370
    • Pattyn, A.1    Morin, X.2    Cremer, H.3    Goridis, C.4    Brunet, J.F.5
  • 49
    • 0037133212 scopus 로고    scopus 로고
    • Transgenesis by lentiviral vectors: lack of gene silencing in mammalian embryonic stem cells and preimplantation embryos
    • Pfeifer A., Ikawa M., Dayn Y., Verma I.M. Transgenesis by lentiviral vectors: lack of gene silencing in mammalian embryonic stem cells and preimplantation embryos. Proc Natl Acad Sci U S A 2002, 99:2140-2145.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 2140-2145
    • Pfeifer, A.1    Ikawa, M.2    Dayn, Y.3    Verma, I.M.4
  • 50
    • 0033987722 scopus 로고    scopus 로고
    • Survival and mitogenesis of neuroepithelial cells are influenced by noradrenergic but not cholinergic innervation in cultured embryonic rat neopallium
    • Popovik E., Haynes L.W. Survival and mitogenesis of neuroepithelial cells are influenced by noradrenergic but not cholinergic innervation in cultured embryonic rat neopallium. Brain Res 2000, 853:227-235.
    • (2000) Brain Res , vol.853 , pp. 227-235
    • Popovik, E.1    Haynes, L.W.2
  • 53
    • 0032841987 scopus 로고    scopus 로고
    • The Phox2 homeodomain proteins are sufficient to promote the development of sympathetic neurons
    • Stanke M., Junghans D., Geissen M., Goridis C., Ernsberger U., Rohrer H. The Phox2 homeodomain proteins are sufficient to promote the development of sympathetic neurons. Development 1999, 126:4087-4094.
    • (1999) Development , vol.126 , pp. 4087-4094
    • Stanke, M.1    Junghans, D.2    Geissen, M.3    Goridis, C.4    Ernsberger, U.5    Rohrer, H.6
  • 54
    • 79953873225 scopus 로고    scopus 로고
    • Interactive effects of development and hypoxia on catecholamine synthesis and cardiac function in zebrafish (Danio rerio)
    • Steele S.L., Ekker M., Perry S.F. Interactive effects of development and hypoxia on catecholamine synthesis and cardiac function in zebrafish (Danio rerio). J Comp Physiol B 2011, 181:527-538.
    • (2011) J Comp Physiol B , vol.181 , pp. 527-538
    • Steele, S.L.1    Ekker, M.2    Perry, S.F.3
  • 55
    • 0034723275 scopus 로고    scopus 로고
    • The homeodomain protein Arix promotes protein kinase A-dependent activation of the dopamine beta-hydroxylase promoter through multiple elements and interaction with the coactivator cAMP-response element-binding protein-binding protein
    • Swanson D.J., Adachi M., Lewis E.J. The homeodomain protein Arix promotes protein kinase A-dependent activation of the dopamine beta-hydroxylase promoter through multiple elements and interaction with the coactivator cAMP-response element-binding protein-binding protein. J Biol Chem 2000, 275:2911-2923.
    • (2000) J Biol Chem , vol.275 , pp. 2911-2923
    • Swanson, D.J.1    Adachi, M.2    Lewis, E.J.3
  • 56
    • 0030828004 scopus 로고    scopus 로고
    • The homeodomain protein Arix interacts synergistically with cyclic AMP to regulate expression of neurotransmitter biosynthetic genes
    • Swanson D.J., Zellmer E., Lewis E.J. The homeodomain protein Arix interacts synergistically with cyclic AMP to regulate expression of neurotransmitter biosynthetic genes. J Biol Chem 1997, 272:27382-27392.
    • (1997) J Biol Chem , vol.272 , pp. 27382-27392
    • Swanson, D.J.1    Zellmer, E.2    Lewis, E.J.3
  • 57
    • 0026611590 scopus 로고
    • Effect of age on [3H]nisoxetine binding to uptake sites for norepinephrine in the locus coeruleus of humans
    • Tejani-Butt S.M., Ordway G.A. Effect of age on [3H]nisoxetine binding to uptake sites for norepinephrine in the locus coeruleus of humans. Brain Res 1992, 583:312-315.
    • (1992) Brain Res , vol.583 , pp. 312-315
    • Tejani-Butt, S.M.1    Ordway, G.A.2
  • 58
    • 0031745285 scopus 로고    scopus 로고
    • Restoration of norepinephrine and reversal of phenotypes in mice lacking dopamine beta-hydroxylase
    • Thomas S.A., Marck B.T., Palmiter R.D., Matsumoto A.M. Restoration of norepinephrine and reversal of phenotypes in mice lacking dopamine beta-hydroxylase. J Neurochem 1998, 70:2468-2476.
    • (1998) J Neurochem , vol.70 , pp. 2468-2476
    • Thomas, S.A.1    Marck, B.T.2    Palmiter, R.D.3    Matsumoto, A.M.4
  • 59
    • 0028935117 scopus 로고
    • Noradrenaline is essential for mouse fetal development
    • Thomas S.A., Matsumoto A.M., Palmiter R.D. Noradrenaline is essential for mouse fetal development. Nature 1995, 374:643-646.
    • (1995) Nature , vol.374 , pp. 643-646
    • Thomas, S.A.1    Matsumoto, A.M.2    Palmiter, R.D.3
  • 60
    • 0027745665 scopus 로고
    • A possible link between cell adhesion receptors, homeodomain proteins and neuronal identity
    • Tissier-Seta J.P., Hirsch M.R., Valarché I., Brunet J.F., Goridis C. A possible link between cell adhesion receptors, homeodomain proteins and neuronal identity. C R Acad Sci III 1993, 316:1305-1315.
    • (1993) C R Acad Sci III , vol.316 , pp. 1305-1315
    • Tissier-Seta, J.P.1    Hirsch, M.R.2    Valarché, I.3    Brunet, J.F.4    Goridis, C.5
  • 61
    • 0029958253 scopus 로고    scopus 로고
    • The expression pattern of the transcription factor Phox2 delineates synaptic pathways of the autonomic nervous system
    • Tiveron M.C., Hirsch M.R., Brunet J.F. The expression pattern of the transcription factor Phox2 delineates synaptic pathways of the autonomic nervous system. J Neurosci 1996, 16:7649-7660.
    • (1996) J Neurosci , vol.16 , pp. 7649-7660
    • Tiveron, M.C.1    Hirsch, M.R.2    Brunet, J.F.3
  • 62
    • 0027489411 scopus 로고
    • The mouse homeodomain protein Phox2 regulates Ncam promoter activity in concert with Cux/CDP and is a putative determinant of neurotransmitter phenotype
    • Valarché I., Tissier-Seta J.P., Hirsch M.R., Martinez S., Goridis C., Brunet J.F. The mouse homeodomain protein Phox2 regulates Ncam promoter activity in concert with Cux/CDP and is a putative determinant of neurotransmitter phenotype. Development 1993, 119:881-896.
    • (1993) Development , vol.119 , pp. 881-896
    • Valarché, I.1    Tissier-Seta, J.P.2    Hirsch, M.R.3    Martinez, S.4    Goridis, C.5    Brunet, J.F.6
  • 63
    • 0017604084 scopus 로고
    • Possible role of dopamine-beta-hydroxylase in the regulation of norepinephrine biosynthesis in rat brain
    • Wise C.D., Belluzzi J.D., Stein L. Possible role of dopamine-beta-hydroxylase in the regulation of norepinephrine biosynthesis in rat brain. Pharmacol Biochem Behav 1977, 7:549-553.
    • (1977) Pharmacol Biochem Behav , vol.7 , pp. 549-553
    • Wise, C.D.1    Belluzzi, J.D.2    Stein, L.3
  • 64
    • 0141459204 scopus 로고    scopus 로고
    • HAND2 synergistically enhances transcription of dopamine-beta-hydroxylase in the presence of Phox2a
    • Xu H., Firulli A.B., Zhang X., Howard M.J. HAND2 synergistically enhances transcription of dopamine-beta-hydroxylase in the presence of Phox2a. Dev Biol 2003, 262:183-193.
    • (2003) Dev Biol , vol.262 , pp. 183-193
    • Xu, H.1    Firulli, A.B.2    Zhang, X.3    Howard, M.J.4
  • 65
    • 0031752431 scopus 로고    scopus 로고
    • Paired-like homeodomain proteins, Phox2a and Phox2b, are responsible for noradrenergic cell-specific transcription of the dopamine beta-hydroxylase gene
    • Yang C., Kim H.S., Seo H., Kim C.H., Brunet J.F., Kim K.S. Paired-like homeodomain proteins, Phox2a and Phox2b, are responsible for noradrenergic cell-specific transcription of the dopamine beta-hydroxylase gene. J Neurochem 1998, 71:1813-1826.
    • (1998) J Neurochem , vol.71 , pp. 1813-1826
    • Yang, C.1    Kim, H.S.2    Seo, H.3    Kim, C.H.4    Brunet, J.F.5    Kim, K.S.6
  • 66
    • 0037337815 scopus 로고    scopus 로고
    • Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases
    • Zarow C., Lyness S.A., Mortimer J.A., Chui H.C. Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases. Arch Neurol 2003, 60:337-341.
    • (2003) Arch Neurol , vol.60 , pp. 337-341
    • Zarow, C.1    Lyness, S.A.2    Mortimer, J.A.3    Chui, H.C.4
  • 67
    • 0029583123 scopus 로고
    • A homeodomain protein selectively expressed in noradrenergic tissue regulates transcription of neurotransmitter biosynthetic genes
    • Zellmer E., Zhang Z., Greco D., Rhodes J., Cassel S., Lewis E.J. A homeodomain protein selectively expressed in noradrenergic tissue regulates transcription of neurotransmitter biosynthetic genes. J Neurosci 1995, 15:8109-8120.
    • (1995) J Neurosci , vol.15 , pp. 8109-8120
    • Zellmer, E.1    Zhang, Z.2    Greco, D.3    Rhodes, J.4    Cassel, S.5    Lewis, E.J.6
  • 68
    • 23244458905 scopus 로고    scopus 로고
    • Age-associated changes in mRNA levels of Phox2, norepinephrine transporter and dopamine beta-hydroxylase in the locus coeruleus and adrenal glands of rats
    • Zhu M.Y., Wang W.P., Iyo A.H., Ordway G.A., Kim K.S. Age-associated changes in mRNA levels of Phox2, norepinephrine transporter and dopamine beta-hydroxylase in the locus coeruleus and adrenal glands of rats. J Neurochem 2005, 94:828-838.
    • (2005) J Neurochem , vol.94 , pp. 828-838
    • Zhu, M.Y.1    Wang, W.P.2    Iyo, A.H.3    Ordway, G.A.4    Kim, K.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.