The mechanical properties and osteoconductivity of hydroxyapatite bone scaffolds with multi-scale porosity

Biomaterials

Volumn 28, Issue 1, 2007, Pages 45-54

  Woodard, Joseph R ^a   Hilldore, Amanda J ^a   Lan, Sheeny K ^a   Park, C J ^a   Morgan, Abby W ^a   Eurell, Jo Ann C ^b   Clark, Sherrie G ^b   Wheeler, Matthew B ^b   Jamison, Russell D ^a   Wagoner Johnson, Amy J ^a  

^a University of Illinois at Urbana Champaign   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Bone ingrowth; Hydroxyapatite; Mechanical properties; Porosity; Rapid prototyping

Indexed keywords

BONE INGROWTH; DRUG CARRIERS; MACROPOROSITY; OSTEOCONDUCTIVITY;

HYDROXYAPATITE; IMPLANTS (SURGICAL); POROSITY; PROTEINS; RAPID PROTOTYPING;

BONE;

DRUG CARRIER; GELATIN; HYDROXYAPATITE; MICROSPHERE; POLY(METHYL METHACRYLATE); RECOMBINANT BONE MORPHOGENETIC PROTEIN 2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE GRAFT; BONE GROWTH; BONE STRENGTH; CANCELLOUS BONE; COMPRESSIVE STRENGTH; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CORTICAL BONE; HISTOLOGY; HUMAN; HUMAN TISSUE; IMPLANTATION; LATISSIMUS DORSI MUSCLE; MATERIALS TESTING; MOLECULAR MECHANICS; NONHUMAN; POROSITY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; STRESS STRAIN RELATIONSHIP; SWINE;

ANIMALS; BONE REGENERATION; DURAPATITE; HUMANS; MICROSCOPY, ELECTRON, SCANNING; OSTEOBLASTS; POROSITY; STRESS, MECHANICAL; SWINE;

EID: 33748904647     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2006.08.021     Document Type: Article

References (50)

1. LaPrade R.F., and Botker J.C. Donor-site morbidity after osteochondral autograft transfer procedures. Arthroscopy 20 7 (2004) e69-e73
2. Silber J.S., Anderson D.G., Daffner S.D., Brislin B.T., Leland J.M., Hilibrand A.S., et al. Donor site morbidity after anterior iliac crest bone harvest for single-level anterior cervical discectomy and fusion. Spine 28 2 (2003) 134-139
3. Nkenke E., Schultze-Mosgau S., Radespiel-Tröger M., Kloss F., and Neukam F.W. Morbidity of harvesting of chin grafts: a prospective study. Clin Oral Implants Res 12 5 (2001) 495-502
4. Kainer M.A., Linden J.V., Whaley D.N., Holmes H.T., Jarvis W.R., Jernigan D.B., et al. Clostridium infections associated with musculoskeletal-tissue allografts. N Engl J Med 350 25 (2004) 2564-2571
5. Palmer S.H., Gibbons C.L., and Athanasou N.A. The pathology of bone allograft. J Bone Jt Surg Br 81 2 (1999) 333-335
6. Cornu O., Banse X., Docquier P.L., Luyckx S., and Delloye C. Effect of freeze-drying and gamma irradiation on the mechanical properties of human cancellous bone. J Orthop Res 18 3 (2000) 426-431
7. Kurashina K., Kurita H., Wu Q., Ohtsuka A., and Kobayashi H. Ectopic osteogenesis with biphasic ceramics of hydroxyapatite and tricalcium phosphate in rabbits. Biomaterials 23 2 (2002) 407-412
8. Jin Q.-M., Takita H., Kohgo T., Atsumi K., Itoh H., and Kuboki Y. Effects of geometry of hydroxyapatite as a cell substratum in BMP-induced ectopic bone formation. J Biomed Mater Res A 51 3 (2000) 491-499
9. Chu T.-M.G., Orton D.G., Hollister S.J., Feinberg S.E., and Halloran J.W. Mechanical and in vivo performance of hydroxyapatite implants with controlled architectures. Biomaterials 23 5 (2002) 1283-1293
10. Dutta Roy T., Simon J.L., Ricci J.L., Rekow E.D., Thompson V.P., and Parsons J.R. Performance of hydroxyapatite bone repair scaffolds created via three-dimensional fabrication techniques. J Biomed Mater Res A 67 4 (2003) 1228-1237
11. Habibovic P., Yuan H., van der Valk C.M., Meijer G., van Blitterswijk C.A., and de Groot K. 3D microenvironment as essential element for osteoinduction by biomaterials. Biomaterials 26 17 (2005) 3565-3575
12. Ge Z., Baguenard S., Lim L.Y., Wee A., and Khor E. Hydroxyapatite-chitin materials as potential tissue engineered bone substitutes. Biomaterials 25 6 (2004) 1049-1058
13. Kaito T., Myoui A., Takaoka K., Saito N., Nishikawa M., Tamai N., et al. Potentiation of the activity of bone morphogenetic protein-2 in bone regeneration by a PLA-PEG/hydroxyapatite composite. Biomaterials 26 1 (2005) 73-79
14. Burstein F.D., Cohen S.R., Hudgins R., Boydston W., and Simms C. The use of hydroxyapatite cement in secondary craniofacial reconstruction. Plast Reconstr Surg 104 5 (1999) 1270-1275
15. Costantino P.D., Chaplin J.M., Wolpoe M.E., Catalano P.J., Sen C., Bederson J.B., et al. Applications of fast-setting hydroxyapatite cement: cranioplasty. Otolaryngol Head Neck Surg 123 4 (2000) 409-412
16. Capello W., D'Antonio J., Manley M., and Feinberg J. Hydroxyapatite in total hip arthroplasty. Clinical results and critical issues. Clin Orthop Relat Res 355 (1998) 200-211
17. Oosterbos C.J.M., Rahmy A.I.A., Tonino A.J., and Witpeerd W. High survival rate of hydroxyapatite-coated hip prostheses: 100 consecutive hips followed for 10 years. Acta Orthop Scand 75 2 (2004) 127-133
18. Bignon A., Chouteau J., Chevalier J., Fantozzi G., Carret J.-P., Chavassieux P., et al. Effect of micro- and macroporosity of bone substitutes on their mechanical properties and cellular response. J Mater Sci Mater Med 14 12 (2003) 1089-1097
19. Hing K.A., Annaz B., Saeed S., Revell P.A., and Buckland T. Microporosity enhances bioactivity of synthetic bone graft substitutes. J Mater Sci Mater Med 16 5 (2005) 467-475
20. Gauthier O., Bouler J.-M., Aguado E., Pilet P., and Daculsi G. Macroporous biphasic calcium phosphate ceramics: influence of macropore diameter and macroporosity percentage on bone ingrowth. Biomaterials 19 1-3 (1998) 133-139
21. Le Nihouannen D., Daculsi G., Saffarzadeh A., Gauthier O., Delplace S., Pilet P., et al. Ectopic bone formation by microporous calcium phosphate ceramic particles in sheep muscles. Bone 36 6 (2005) 1086-1093
22. Hing K.A., Best S.M., Tanner K.E., Bonfield W., and Revell P.A. Mediation of bone ingrowth in porous hydroxyapatite bone graft substitutes. J Biomed Mater Res A 68 1 (2002) 187-200
23. Kalita S.J., Bose S., Hosick H.L., and Bandyopadhyay A. Development of controlled porosity polymer-ceramic composite scaffolds via fused deposition modeling. Mater Sci Eng C 23 5 (2003) 611-620
24. Hollister S.J., Maddox R.D., and Taboas J.M. Optimal design and fabrication of scaffolds to mimic tissue properties and satisfy biological constraints. Biomaterials 23 20 (2002) 4095-4103
25. Lin C.Y., Kikuchi N., and Hollister S.J. A novel method for biomaterial scaffold internal architecture design to match bone elastic prooperties with desired porosity. J Biomech 37 5 (2004) 623-636
26. Michna S., Wu W., and Lewis J.A. Concentrated hydroxyapatite inks for direct-write assembly of 3-D periodic scaffolds. Biomaterials 26 28 (2005) 5632-5639
27. Dellinger JG. Development of model hydroxyapatite bone scaffolds with multiscale porosity for potential load bearing applications. Dissertation, University of Illinois at Urbana-Champaign, 2005.
28. Dellinger J.G., Eurell J.A.C., and Jamison R.D. Bone response to 3D periodic hydroxyapatite scaffolds with and without tailored microporosity to deliver bone morphogenetic protein 2. J Biomed Mater Res A 76 2 (2005) 366-376
29. Sterchi D.L., and Eurell J.A.C. An evaluation of methylmethacrylate mixtures for hard tissue embedding. J Histotechnol 18 1 (1995) 45-49
30. Schenk R.K., Olah A.J., and Herrmann W. Preparation of calcified tissues for light microscopy. In: Dickson G.R. (Ed). Methods of calcified tissue preparation (1984), Elsevier, Amsterdam 1-56
31. ASTM. C 1424-99 Standard test method for monotonic compressive strength of advanced ceramics at ambient temperature. Annual Book of ASTM Standards (2001), ASTM, West Conshohocken, PA p. 673-85
32. Gibson L.J., and Ashby M.F. Cellular solids: structure and properties. 2nd ed (1997), Pergamon Press, Oxford
33. Hayes W., and Carter D.R. Postyield behavior of subchondral trabecular bone. J Biomed Mater Res 10 4 (1976) 537-544
34. Mosekilde L., and Mosekilde L. Normal vertebral body size and compressive strength: relations to age and to vertebral and iliac trabecular bone compressive strength. Bone 7 3 (1986) 207-212
35. McCalden R.W., McGeough J.A., and Court-Brown C.M. Age-related changes in the compressive strength of cancellous bone. The relative importance of changes in density and trabecular architecture. J Bone Jt Surg Am 79 3 (1997) 421-427
36. Kopperdahl D.L., and Keaveny T.M. Yield strain behavior of trabecular bone. J Biomech 31 7 (1998) 601-608
37. Dempster W.T., and Liddicoat R.T. Compact bone as a non-isotropic material. Am J Anat 91 (1952) 331-359
38. Cezayirlioglu H., Bahniuk E., Davy D.T., and Heiple K.G. Anisotropic yield behavior of bone under combined axial force and torque. J Biomech 18 1 (1985) 61-69
39. McElhaney J.H. Dynamic response of bone and muscle tissue. J Appl Physiol 21 4 (1966) 1231-1236
40. Reilly D.T., and Burstein A.H. The elastic and ultimate properties of compact bone tissue. J Biomech 8 6 (1975) 393-405
41. Turner C.H., Rho J., Takano Y., Tsui T.Y., and Pharr G.M. The elastic properties of trabecular and cortical bone tissues are similar: results from two microscopic measurement techniques. J Biomech 32 4 (1999) 437-441
42. Rho J.-Y., Tsui T.Y., and Pharr G.M. Elastic properties of human cortical and trabecular lamellar bone measured by nanoindentation. Biomaterials 18 20 (1997) 1325-1330
43. Bayraktar H.H., Morgan E.F., Niebur G.L., Morris G.E., Wong E.K., and Keaveny T.M. Comparison of the elastic and yield properties of human femoral trabecular and cortical bone tissue. J Biomech 37 1 (2004) 27-35
44. Yamamoto M., Takahashi Y., and Tabata Y. Controlled release by biodegradable hydrogels enhances the ectopic bone formation of bone morphogenetic protein. Biomaterials 24 24 (2003) 4375-4383
45. Woo B.H., Fink B.F., Page R., Schrier J.A., Jo Y.W., Jiang G., et al. Enhancement of bone growth by sustained delivery of recombinant human bone morphogenetic protein-2 in a polymeric matrix. Pharm Res 18 12 (2001) 1747-1753
46. Reddi A.H. Morphogenesis and tissue engineering of bone and cartilage: inductive signals, stem cells, and biomimetic biomaterials. Tissue Eng 6 4 (2000) 351-359
47. Woodard JR. An in vivo study of the mechanical behavior and osteoconductivity of porous hydroxyapatite bone scaffolds. Thesis, University of Illinois at Urbana-Champaign, 2006.
48. Wenisch S., Stahl J.P., Horas U., Heiss C., Kilian O., Trinkaus K., et al. In vivo mechanisms of hydroxyapatite ceramic degradation by osteoclasts: fine structural microscopy. J Biomed Mater Res A 67 3 (2003) 713-718
49. Gomi K., Lowenberg B., Shapiro G., and Davies J.E. Resorption of sintered synthetic hydroxyapatite by osteoclasts in vitro. Biomaterials 14 2 (1993) 91-96
50. Roux S., and Orcel P. Bone loss: factors that regulate osteoclast differentiation-an update. Arthritis Res 2 6 (2000) 451-456