Increased adipocyte S-nitrosylation targets anti-lipolytic action of insulin: Relevance to adipose tissue dysfunction in obesity

Journal of Biological Chemistry

Volumn 286, Issue 35, 2011, Pages 30433-30443

  Ovadia, Hilla ^a   Haim, Yulia ^a   Nov, Ori ^a   Almog, Orna ^a   Kovsan, Julia ^a   Bashan, Nava ^a,c   Benhar, Moran ^b   Rudich, Assaf ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^c Fraida Foundation in Diabetes Research   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTES; ADIPOSE TISSUE; ANTI-LIPOLYTIC ACTION; BODY WEIGHT; CELL LINES; INSULIN RECEPTORS; INSULIN RESISTANCE; INSULIN-STIMULATED GLUCOSE; ISOPROTERENOL; MRNA EXPRESSION; NO DONOR; OBESE MICE; PATHOPHYSIOLOGICAL; PROTEIN FUNCTIONS; PROTEIN LEVEL; PROTEIN MODIFICATIONS; S-NITROSOGLUTATHIONE; S-NITROSYLATION; SITE DIRECTED MUTAGENESIS; SKELETAL MUSCLE; SUBSTRATE-BINDING SITES; SYNTHASES; THIOREDOXIN REDUCTASE; TOTAL PROTEIN;

BINDING SITES; CELL CULTURE; ENZYME ACTIVITY; GLUCOSE; MAMMALS; MOLECULAR WEIGHT; NUTRITION; PHOSPHORYLATION; PROTEINS; SUBSTRATES; TISSUE;

INSULIN;

CYCLIC AMP DEPENDENT PROTEIN KINASE; CYSTEINE; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3; INDUCIBLE NITRIC OXIDE SYNTHASE; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR BETA; ISOPRENALINE; MESSENGER RNA; N ACETYL S NITROSOPENICILLAMINE; PHOSPHODIESTERASE III; PHOSPHODIESTERASE IIIB; PROTEIN KINASE B; S NITROSOGLUTATHIONE; THIOREDOXIN REDUCTASE; UNCLASSIFIED DRUG;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; BODY WEIGHT; CELL LINE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; FEMALE; GENETIC TRANSFECTION; GLUCOSE TRANSPORT; HORMONE ACTION; HUMAN; HUMAN TISSUE; LIPID DIET; MALE; MOUSE; NITROSYLATION; NONHUMAN; OBESITY; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

ADIPOCYTES; ADIPOSE TISSUE; ANIMALS; CYSTEINE; FEMALE; HUMANS; INSULIN; INSULIN RESISTANCE; LIPOLYSIS; MALE; MICE; MICE, INBRED C57BL; MUTAGENESIS, SITE-DIRECTED; NITROGEN; OBESITY; OXIDATIVE STRESS; PHOSPHORYLATION;

MUS;

EID: 80052235110     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.235945     Document Type: Article

References (47)

1. Stamler, J. S., Simon, D. I., Osborne, J. A., Mullins, M. E., Jaraki, O., Michel, T., Singel, D. J., and Loscalzo, J. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 444-448
2. Stamler, J. S., Toone, E. J., Lipton, S. A., and Sucher, N. J. (1997) Neuron 18, 691-696
3. Foster, M. W., Hess, D. T., and Stamler, J. S. (2009) Trends Mol. Med. 15, 391-404
4. Lane, P., Hao, G., and Gross, S. S. (2001) Sci STKE 2001, re1
5. Nathan, C., and Xie, Q. W. (1994) Cell 78, 915-918
6. Brüne, B., Mohr, S., and Messmer, U. K. (1996) Rev. Physiol. Biochem. Pharmacol. 127, 1-30
7. Kaneki, M., Shimizu, N., Yamada, D., and Chang, K. (2007) Antioxid. Redox. Signal. 9, 319-329
8. Wellen, K. E., and Hotamisligil, G. S. (2005) J. Clin. Invest. 115, 1111-1119
9. Elizalde, M., Rydén, M., van Harmelen, V., Eneroth, P., Gyllenhammar, H., Holm, C., Ramel, S., Olund, A., Arner, P., and Andersson, K. (2000) J. Lipid Res. 41, 1244-1251
10. Engeli, S., Janke, J., Gorzelniak, K., Böhnke, J., Ghose, N., Lindschau, C., Luft, F. C., and Sharma, A. M. (2004) J. Lipid Res. 45, 1640-1648
11. Sugita, H., Fujimoto, M., Yasukawa, T., Shimizu, N., Sugita, M., Yasuhara, S., Martyn, J. A., and Kaneki, M. (2005) J. Biol. Chem. 280, 14203-14211
12. Carvalho-Filho, M. A., Ueno, M., Hirabara, S. M., Seabra, A. B., Carvalheira, J. B., de Oliveira, M. G., Velloso, L. A., Curi, R., and Saad, M. J. (2005) Diabetes 54, 959-967
13. Perreault, M., and Marette, A. (2001) Nat. Med. 7, 1138-1143
14. Carvalho-Filho, M. A., Ueno, M., Carvalheira, J. B., Velloso, L. A., and Saad, M. J. (2006) Am. J. Physiol. Endocrinol. Metab. 291, E476-E482
15. Yasukawa, T., Tokunaga, E., Ota, H., Sugita, H., Martyn, J. A., and Kaneki, M. (2005) J. Biol. Chem. 280, 7511-7518
16. Kitamura, T., Kitamura, Y., Kuroda, S., Hino, Y., Ando, M., Kotani, K., Konishi, H., Matsuzaki, H., Kikkawa, U., Ogawa, W., and Kasuga, M. (1999) Mol. Cell. Biol. 19, 6286-6296
17. Kolditz, C. I., and Langin, D. (2010) Curr. Opin. Clin. Nutr. Metab. Care 13, 377-381
18. Arner, P. (2003) Trends Endocrinol. Metab. 14, 137-145
19. Souza, S. C., Yamamoto, M. T., Franciosa, M. D., Lien, P., and Greenberg, A. S. (1998) Diabetes 47, 691-695
20. Bashan, N., Dorfman, K., Tarnovscki, T., Harman-Boehm, I., Liberty, I. F., Blüher, M., Ovadia, S., Maymon-Zilberstein, T., Potashnik, R., Stumvoll, M., Avinoach, E., and Rudich, A. (2007) Endocrinology 148, 2955-2962
21. Blüher, M., Bashan, N., Shai, I., Harman-Boehm, I., Tarnovscki, T., Avinaoch, E., Stumvoll, M., Dietrich, A., Klöting, N., and Rudich, A. (2009) J. Clin. Endocrinol. Metab. 94, 2507-2515
22. Harman-Boehm, I., Blüher, M., Redel, H., Sion-Vardy, N., Ovadia, S., Avinoach, E., Shai, I., Klöting, N., Stumvoll, M., Bashan, N., and Rudich, A. (2007) J. Clin. Endocrinol. Metab. 92, 2240-2247
23. Konrad, D., Rudich, A., and Schoenle, E. J. (2007) Diabetologia 50, 833-839
24. Kovsan, J., Osnis, A., Maissel, A., Mazor, L., Tarnovscki, T., Hollander, L., Ovadia, S., Meier, B., Klein, J., Bashan, N., and Rudich, A. (2009) Am. J. Physiol. Endocrinol. Metab. 296, E315-E322
25. Kovsan, J., Ben-Romano, R., Souza, S. C., Greenberg, A. S., and Rudich, A. (2007) J. Biol. Chem. 282, 21704-21711
26. Forrester, M. T., Foster, M. W., Benhar, M., and Stamler, J. S. (2009) Free Radic. Biol. Med. 46, 119-126
27. Tirosh, A., Potashnik, R., Bashan, N., and Rudich, A. (1999) J. Biol. Chem. 274, 10595-10602
28. Nikitovic, D., and Holmgren, A. (1996) J. Biol. Chem. 271, 19180-19185
29. Hibbs, J. B., Jr., Taintor, R. R., Vavrin, Z., and Rachlin, E. M. (1988) Biochem. Biophys. Res. Commun. 157, 87-94
30. Weinberg, J. B., Misukonis, M. A., Shami, P. J., Mason, S. N., Sauls, D. L., Dittman, W. A., Wood, E. R., Smith, G. K., McDonald, B., Bachus, K. E., et al. (1995) Blood 86, 1184-1195
31. Suganami, T., Nishida, J., and Ogawa, Y. (2005) Arterioscler. Thromb. Vasc. Biol. 25, 2062-2068
32. Kane, S., Sano, H., Liu, S. C., Asara, J. M., Lane, W. S., Garner, C. C., and Lienhard, G. E. (2002) J. Biol. Chem. 277, 22115-22118
33. Loten, E. G. (1991) Int. J. Biochem. 23, 649-655
34. Manganiello, V. C., Murata, T., Taira, M., Belfrage, P., and Degerman, E. (1995) Arch. Biochem. Biophys. 322, 1-13
35. Degerman, E., Landström, T. R., Wijkander, J., Holst, L. S., Ahmad, F., Belfrage, P., and Manganiello, V. (1998) Methods 14, 43-53
36. Furukawa, S., Fujita, T., Shimabukuro, M., Iwaki, M., Yamada, Y., Nakajima, Y., Nakayama, O., Makishima, M., Matsuda, M., and Shimomura, I. (2004) J. Clin. Invest. 114, 1752-1761
37. Houstis, N., Rosen, E. D., and Lander, E. S. (2006) Nature 440, 944-948
38. Bashan, N., Kovsan, J., Kachko, I., Ovadia, H., and Rudich, A. (2009) Physiol. Rev. 89, 27-71
39. Davì, G., Falco, A., and Patrono, C. (2005) Antioxid. Redox. Signal. 7, 256-268
40. Nishikawa, T., Sasahara, T., Kiritoshi, S., Sonoda, K., Senokuchi, T., Matsuo, T., Kukidome, D., Wake, N., Matsumura, T., Miyamura, N., Sakakida, M., Kishikawa, H., and Araki, E. (2003) Diabetes Care 26, 1507-1512
41. Rehman, A., Nourooz-Zadeh, J., Möller, W., Tritschler, H., Pereira, P., and Halliwell, B. (1999) FEBS Lett. 448, 120-122
42. Dalle-Donne, I., Giustarini, D., Colombo, R., Rossi, R., and Milzani, A. (2003) Trends Mol. Med. 9, 169-176
43. Pauli, J. R., Ropelle, E. R., Cintra, D. E., Carvalho-Filho, M. A., Moraes, J. C., De Souza, C. T., Velloso, L. A., Carvalheira, J. B., and Saad, M. J. (2008) J. Physiol. 586, 659-671
44. Benhar, M., Forrester, M. T., and Stamler, J. S. (2009) Nat. Rev. Mol. Cell Biol. 10, 721-732
45. Lillig, C. H., and Holmgren, A. (2007) Antioxid. Redox. Signal. 9, 25-47
46. Nathan, C. (1997) J. Clin. Invest. 100, 2417-2423
47. Scapin, G., Patel, S. B., Chung, C., Varnerin, J. P., Edmondson, S. D., Mastracchio, A., Parmee, E. R., Singh, S. B., Becker, J. W., Van der Ploeg, L. H., and Tota, M. R. (2004) Biochemistry 43, 6091-6100