Analysis of the cell cycle regulatory protein (E2F1) after infection of cultured cells with bovine herpesvirus 1 (BHV-1) or herpes simplex virus type 1 (HSV-1)

Virus Research

Volumn 160, Issue 1-2, 2011, Pages 66-73

  Workman, Aspen ^a,b   Jones, Clinton ^a,b  

^a UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^b UNIVERSITY OF NEBRASKA   (United States)

Author keywords

Bovine herpesvirus 1; E2F dependent transcription; Herpes simplex virus type 1; Productive infection

Indexed keywords

CYCLIN D1; TRANSCRIPTION FACTOR E2F1;

ANIMAL CELL; ARTICLE; BOVINE HERPES VIRUS; CELL LINE; HERPES SIMPLEX VIRUS 1; HERPES VIRUS INFECTION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; TRANSCRIPTION REGULATION; VIRUS CELL INTERACTION;

ANIMALS; CELL CYCLE; CELL NUCLEUS; CELLS, CULTURED; CYTOPLASM; E2F1 TRANSCRIPTION FACTOR; GENE SILENCING; HERPESVIRUS 1, BOVINE; HERPESVIRUS 1, HUMAN; HOST-PATHOGEN INTERACTIONS; RABBITS; VIRUS REPLICATION;

BOVINE HERPESVIRUS 1; HUMAN HERPESVIRUS 1; ORYCTOLAGUS CUNICULUS;

EID: 80052169080     PISSN: 01681702     EISSN: 18727492     Source Type: Journal    
DOI: 10.1016/j.virusres.2011.05.009     Document Type: Article

References (45)

1. Advani S.J., Brandimarti R., Weichselbaum R.R., Roizman B. The disappearance of cyclins A and B and the increase in activity of the G2/M-phase cellular kinase cdc2 in herpes simplex virus 1-infected cells require expression of the alpha22/Us1.5 and UL13 viral genes. J. Virol. 2000, 74:8-15.
2. Advani S.J., Weichselbaum R.R., Roizman B. E2F proteins are posttranslationally modified concomitantly with a reduction in nuclear binding activity in cells infected with herpes simplex virus 1. J. Virol. 2000, 74:7842-7850.
3. Attwooll C., Denchi E.L., Helin K. The E2F family: specific functions and overlapping interests. EMBO J. 2004, 23:4709-4716.
4. Boutell C., Everett R.D. Herpes simplex virus type 1 infection induces the stabilization of p53 in a USP7- and ATM-independent manner. J. Virol. 2004, 78:8068-8077.
5. Chang Y.C., Nakajima H., Illenye S., Lee Y.S., Honjo N., Makiyama T., Fujiwara I., Mizuta N., Sawai K., Saida K., Mitsui Y., Heintz N.H., Magae J. Caspase-dependent apoptosis by ectopic expression of E2F-4. Oncogene 2000, 19:4713-4720.
6. Chee M.S., Lawrence G.L., Barell B.G. Alpha-, beta-, and gammaherpesviruses encode a putative phosphotransferase. J. Gen. Virol. 1989, 70:1151-1161.
7. Corcoran J.A., Hsu W.-L., Smiley J.R. Herpes simplex virus ICP27 is required for virus-induced stabilization of the ARE-containing IEX-1 mRNA encoded by the human IER3 gene. J. Virol. 2006, 80:9720-9729.
8. DeGregori J., Kowalik T., Nevins J.R. Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes. Mol. Cell. Biol. 1995, 15:4215-4224.
9. Devireddy L.R., Jones C. Activation of caspases and p53 by bovine herpesvirus 1 infection results in programmed cell death and efficient virus release. J. Virol. 1999, 73:3778-3788.
10. Devireddy L., Jones C. Olf-1, a neuron-specific transcription factor, can activate the herpes simplex virus 1 ICP0 promoter. J Biol Chem 2000, 275:77-81.
11. Ehmann G.L., Burnett H.A., Bachenheimer S.L. Pocket protein p130/Rb2 is required for efficient herpes simplex virus type 1 gene expression and viral replication. J. Virol. 2001, 75:7149-7160.
12. Flemington E.K. Herpesvirus lytic replicationand the cell cycle: arresting new developments. J. Virol. 2001, 75:4475-4481.
13. Frame M.C., Purves F.C., McGeoch D.J., Mardsen H.S., Leader D.P. Identification of the herpes simplex virus protein kinase as the product of viral gene US3. J. Gen. Virol. 1987, 68:2699-2704.
14. Garcia-Alvarez G., Ventura V., Ros O., Aligue R., Gil J., Tauler A. Glycogen synthase kinase-3b binds to E2F1 and regulates its transscriptional activity. Biochim. Biophys. Acta 2007, 1773:375-382.
15. Geiser V., Jones C. Stimulation of bovine herpesvirus 1 productive infection by the adneovirus E1A gene and a cell cycle regulatory gene, E2F-4. J. Gen. Virol. 2003, 84:929-938.
16. Gottlieg J., Challberg M.D. Interaction of herpes simplex virus type 1 DNA polymerase and the UL42 accessory protein with a model template. J. Virol. 1994, 68:4937-4945.
17. Harbour J.W., Dean D.C. The Rb/E2F pathway: expanding roles and emerging paradigms. Genes Dev. 2000, 14:2393-2409.
18. Hargett D., McLean T., Bachenheimer S.L. Herpes simplex virus ICP27 activation of stress kinase JNK and p38. J. Virol. 2005, 79:8348-8360.
19. Helin K., Wu C.L., Fattaey A.R., Lees J.A., Dynlacht B.D., Ngwu C., Harlow E. Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation. Genes Dev. 1993, 7:1850-1861.
20. Hilton M.J., Mounghane D., McLean T., Contractor N.V., O'Neil J., Carpenter K., Bachenheimer S.L. Induction by herpes simplex virus of free and heteromeric forms of E2F transcription factor. Virology 1995, 213:624-638.
21. Hobbs W.E., DeLuca N.A. Perturbation of cell cycle progression and cellular gene expression as a function of herpes simplex virus ICP0. J. Virol. 1999, 73:8245-8255.
22. Ingram L., Munro S., Coutts A.S., La Thangue N.B. E2F-1 regulation by an unusual DNA damage-responsive DP partner subunit. Cell Death Differ. 2011, 18:122-132.
23. Jones C. Alphaherpesvirus latency: its role in disease and survival of the virus in nature. Adv. Virus Res. 1998, 51:81-133.
24. Jones C. Herpes simplex virus type 1 and bovine herpesvirus 1 latency. Clin. Micro Rev. 2003, 16:79-95.
25. Kushnir A.S., Davido D.J., Schaffer P.A. Role of the nuclear factor Y in stress-induced activation of the herpes simplex virus type 1 ICP0 promoter. J. Virol. 2010, 84:188-200.
26. Lomonte P., Everett R.D. Herpes simplex virus type 1 immdeiate-early protein Vmw110 inhibits progression of cells through mitosis and from G1 into S phase of the cell cycle. J. Virol. 1999, 73:9456-9467.
27. Nevins J.R., DeGregori J., L.Jakoi L., Leone G. Functional analysis of E2F transcription factor. Meth. Enzymol. 1997, 283:205-219.
28. Nip J., Strom D.K., Fee B.E., Zambetti G., Cleveland J.L., Hiebert S.W. E2F-1 cooperates with topoisomerase II inhibition and DNA damage to selectively augment p53-independent apoptosis. Mol. Cell. Biol. 1997, 17:1049-1056.
29. Ohtani K., DeGregori J., Nevins J.R. Regulation of the cyclin E gene by transcription factor E2F1. Proc. Natl. Acad. Sci. U.S.A. 1995, 92:12146-12150.
30. Olgiate J., Ehmann G.L., Vidyarthi S., Hilton M.J., Bachenheimer S.L. Herpes simplex virus induces intracellular redistribution of E2F4 and accumulation of E2F pocket protein complexes. Virology 1999, 258:257-270.
31. Orlando J.S., Astor T.L., Rundle S.A., Schaffer P.A. The products of the herpes simplex virus type 1 immediate-early Us1/Us1.5 genes downregulate levells of S-phase-specific cyclins and facilitate virus replication in S-phase vero cells. J. Virol. 2006, 80:4005-4016.
32. Purves F.C., Longnecker R.M., Leader D.P., Roizman B. Herpes simplex virus 1 protein kinase is encoded by open reading frame US3 which is not essential for virus growth in cell culture. J. Virol. 1987, 61:2896-2901.
33. Real S., Espada L., Espinet C., Santidrian A.F., Tauler A. Study of the in vivo phosphorylation of E2F1 on Ser403. Biochim. Biophys. Acta 2010, 1803:912-918.
34. Schang L., Rosenberg A., Schaffer P. Transcription of herpes simplex virus immediate-early and early genes is inhibited by roscovitine, an inhibitor specific for cellular cyclin-dependent kinases. J. Virol. 1999, 73:2161-2172.
35. Schang L., Phillips J., Schaffer P. Requirement for cellular cyclin-dependent kinases in herpes simplex virus replication and transcription. J. Virol. 1998, 72:5626-5637.
36. Schulze A., Zerfass K., Spitkovsky D., Middendorp S., Berges J., Helin K., Jansen-Durr P., Henglein B. Cell cycle regulation of the cyclin A gene promoter is mediated by a variant E2F site. Proc. Natl. Acad. Sci. U.S.A. 1995, 92:11264-11268.
37. Smith R.F., Smith T.F. Identification of new protein kinase-related genes in three herpesviruses, herpes simplex virus, varicella zoster virus, and Epstein-Barr virus. J. Virol. 1989, 63:450-455.
38. Song B.K., Yeh C., Liu J., Knipe D.M. Herpes simplex virus gene products required for viral inhibition of expression of G1-phase functions. Virology 2001, 290:320-328.
39. Weei-Chin L., Lin F.-T., Nevins J.R. Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation. Genes Dev. 2011, 15:1833-1844.
40. Weintraub S.J., Prater C.A., Dean D.C. Retinoblastoma protein switches the E2F site from positive to negative element. Nature 1992, 358:259-261.
41. Wells J.M., Illenye S., Magae J., Wu C.L., Heintz N.H. Accumulation of E2F-4.DP-1 DNA binding complexes correlates with induction of dhfr gene expression during the G1 to S phase transition. J. Biol. Chem. 1997, 272:4483-4492.
42. Winkler M.T., Schang L.S., Doster A., Holt T., Jones C. Analysis of cyclins in trigeminal ganglia of calves infected with bovine herpesvirus-1. J. Gen. Virol. 2000, 81:2993-2998.
43. Workman A., Sinani D., Pittayakhajonwut D., Jones C. A protein (ORF2) encoded by the latency related gene of bovine herpesvirus 1 interacts with Notch1 and Notch3. J. Virol. 2011, 85:2536-2546.
44. Workman A., Perez S., Doster A., Jones C. Dexamethasone treatment of calves latently infected with bovine herpesvirus 1 (BHV-1) leads to activation of the bICP0 early promoter, in part by the cellular transcription factor C/EBP-alpha. J. Virol. 2009, 83:8800-8809.
45. Workman A., Jones C. Bovine herpesvirus 1 productive infection and bICP0 early promoter activity are stimulated by E2F1. J. Virol. 2010, 84:6308-6317.