The disappearance of cyclins A and B and the increase in activity of the G2/M-phase cellular kinase cdc2 in herpes simplex virus 1-infected cells require expression of the α22/U(S)1.5 and U(L)13 viral genes

Journal of Virology

Volumn 74, Issue 1, 2000, Pages 8-15

  Advani, S J ^a   Brandimarti, R ^a   Weichselbaum, R R ^a   Roizman, B ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; CYCLIN A; CYCLIN B; GENE PRODUCT; PHOSPHATASE;

ARTICLE; CELL CYCLE G2 PHASE; CELL LYSATE; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; GENE EXPRESSION; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; VIRUS GENE;

EID: 0033989874     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.74.1.8-15.2000     Document Type: Article

References (47)

1. Atherton-Fessler, S., F. Liu, B. Gabrielli, M. S. Lee, P. Cheng-Yuan, and H. Piwnica-Worms. 1994. Cell cycle regulation of the p34cdc inhibitory kinases. Mol. Biol Cell 5:989-1001.
2. Barratt, R. A., G. Kao, W. G. McKenna, J. Kuang, and R. J. Muschel. 1998. The G2 block induced by DNA damage: a caffeine-resistant component independent of cdc25C, mpm-2 phosphorylation, and H1 kinase activity. Cancer Res. 58:2639-2645.
3. Berns, J. I. 1996. Parvoviridae: the viruses and their replication, p. 2173-2197. In B. N. Fields, D. M. Knipe, and P. M. Howley (ed.), Virology, 3rd ed., vol. 2. Lippincott-Raven, Philadelphia, Pa.
4. Booher, R. N., P. S. Hlman, and A. Fattaey. 1997. Human mytl is a cell cycle-regulated kinase that inhibits cdc2 but not dck2 activity. J. Biol. Chem. 272:22300-22306.
5. Bruni, R., and B. Roizman. 1998. Herpes simplex virus 1 regulatory protein ICP22 interacts with a new cell cycle-regulated factor and accumulates in a cell cycle-dependent fashion in infected cells. J. Virol. 72:8525-8531.
6. Cole, C. N. 1996. Polyomavirinae: the viruses and their replication, p. 1997-2025. In B. N. Fields, D. M. Knipe, and P. M. Howley (ed.). Virology, 3rd ed., vol. 2. Lippincott-Raven, Philadelphia, Pa.
7. Ding, M., Y. Feng, and D. D. Vandre. 1997. Partial characterization of the mpm-2 phosphoepitope. Exp. Cell Res. 231:3-13.
8. Draetta, G., and D. Beach. 1988. Activation of cdc2 protein kinase during mitosis in human cells: cell cyde-dependent phosphorylation and subunit regulation. Cell 54:17-26.
9. Draetta, G., H. Piwnica-Worms, D. Morrison, B. Druker, T. Roberts, and D. Beach. 1988. Human cdc2 protein kinase is a major cell-cycle regulated tyrosine kinase substrate. Nature 336:738-744.
10. Draetta, G., and J. Eckstein. 1997. Cdc25 protein phosphatases in cell proliferation. Biochim. Biophys. Acta 1332:M53-M63.
11. Ejercito, P., E. D. Kieff, and B. Roizman. 1968. Characterization of herpes simplex virus strains differing in their effects on social behavior of infected cells. J. Gen. Virol. 2:357-364.
12. Goto, H., S. Motomura, A. C. Wilson, R. N. Freiman, Y. Nakabeppu, K. Fukushima, M. Fujishima, W. Herr, and T. Nishimoto. 1997. A single point mutation in HCF causes temperature-sensitive cell cycle arrest and disrupts mutations VP16 function. Genes Dev. 11:726-737.
13. Heichman, K. A., and J. M. Roberts. 1994. Rules to replicate by. Cell 79:557-562.
14. Hilton, M. J., D. Mounghane, T. McLean, N. V. Contractor, J. O'Neil, K. Carpenter, and S. L. Bachenheimer. 1995. Induction by herpes simplex virus of free and heteromeric forms of E2F transcription factor. Virology 213: 624-638.
15. Hoffmann, I., P. R. Clarke, M. J. Marcote, E. Karsenti, and G. Draetta. 1993. Phosphorylation and activation of cdc25-C by cdc2-cyclin B and its involvement in the self amplification of MPF at mitosis. EMBO J. 12:53-63.
16. Hossain, A., T. Holt, J. Ciacci-Zanella, and C. Jones. 1997. Analysis of cyclin-dependent kinase activity after herpes simplex virus type 2 infection. J. Gen. Virol. 78:3341-3348.
17. Howley, P. M. 1996. Papillomavirinae: the viruses and their replication, p. 2045-2076. In B. N. Fields, D. M. Knipe, and P. M. Howley (ed.), Virology, 3rd ed., vol. 2. Lippincott-Raven, Philadelphia, Pa.
18. Kawaguchi, Y., C. Van Sant, and B. Roizman. 1997. Herpes simplex virus 1 α regulatory protein ICP0 interacts with and stabilizes the cell cycle regulator cyclin D3. J. Virol. 71:7328-7336.
19. Kawaguchi, Y., C. Van Sant, and B. Roizman. 1998. Eukaryotic elongation factor 1δ is hyperphosphorylated by the protein kinase encoded by the U, 13 gene of herpes simplex virus 1. J. Virol. 72:1731-1736.
20. Kawaguchi, Y., T. Matsumura, B. Roizman, and K. Hirai. 1999. Cellular elongation factor 1δ is modified in cells infected with representative alpha-, beta-, or gammaherpesviruses. J. Virol. 73:4456-4460.
21. King, R. W., P. K. Jackson, and M. W. Kirschner. 1994. Mitosis in transition. Cell 79:563-571.
22. Kuang, J., C. L. Ashorn, M. Gonzalez-Kuyvenhoven, and J. E. Penkala. 1994. Cdc25 is one of the mpm-2 antigens involved in the activation of maturation-promoting factor. Mol. Biol. Cell 5:135-145.
23. Kumagai, A., and W. G. Dunphy. 1992. Regulation of the cdc25 protein during the cell cycle in Xenopus extracts Cell 70:139-151.
24. McGowan, C. H., and P. Russell. 1995. Cell cycle regulation of human weel. EMBO J. 14:2166-2175.
25. cdc2 kinase in fission yeast. EMBO J. 10:4301-4309.
26. Moria, A. O., G. Draetta, D. Beach, and J. Y. J. Wang. 1989. Reversible tyrosine phosphorylation of cdc2: dephosphorylation accompanies activation during entry in mitosis. Cell 58:193-203.
27. Ng, T. I., Y. E. Chang, and B. Roizman. 1997. Infected cell protein 22 of herpes simplex virus regulates the expression of virion host shutoff gene UL41. Virology 234:226-234.
28. Nurse, P. 1994. Ordering S phase and M phase in the cell cycle. Cell 79:547-550.
29. S1.5 protein. J. Virol 73:4305-4315.
30. O'Reilly, D., O. Hanscombe, and P. O'Hare. 1997. A single serine residue at position 375 of VF16 is critical for complex assembly with Oct-1 and HCF and is a target of phosphorylation by casein kinase II. EMBO J. 16:2420-2430.
31. cdc2-cyclin B complex by the human weel tyrosine kinase. Science 257:1955-1957.
32. Parker, L. L., P. J. Sylvestre, M. J. Byrnes III, K. Liu, and H. Piwnica-Worms. 1995. Identification of a 95-kDa weel-like tyrosine kinase in HeLa cells. Proc. Natl. Acad. Sci. USA 92:9638-9642.
33. Peng, C. Y., P. R. Graves, R. S. Thoma, Z. Wu, A. S. Shaw, and H. Piwnica-Worms. 1997. Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of cdc25C on serine-216. Science 277:1501-1505.
34. Peter, M., J. Nakagawa, M. Doree, J. C. Labbe, and E. A. Nigg. 1990. In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamin by cdc2 kinase. Cell 61:591-602.
35. L13 gene of herpes simplex virus 1 encodes the functions for posttranslational processing associated with phosphorylation of the regulatory protein α22. Proc. Natl. Acad. Sci. USA 89:7310-7314.
36. L13 protein kinase determines the accumulation of a subset of alpha and gamma mRNAs and proteins in infected cells. Proc. Natl. Acad. Sci. USA 90:6701-6705.
37. Roizman, B. 1961. Virus infection of cells in mitosis. I. Observations on the recruitment on cells in karyokinesis into giant cells induced by herpes simplex virus and bearing on the site of antigen formation. Virology 13:387-401.
38. Roizman, B., and P. R. Roane, Jr. 1964. Multiplication of herpes simplex virus. II. The relation between protein synthesis and the duplication of viral DNA in infected HEp-2 cells. Virology 22:262-269.
39. Roizman, B., and A. K. Sears. 1996. Herpes simplex viruses and their replication, p. 2231-2296. In B. N. Fields, D. M. Knipe, and P. M. Howley (ed.), Fields virology, 3rd ed. Lippincott-Raven, Philadelphia, Pa.
40. Roller, R. J., and B. Roizman. 1992. The herpes simplex virus 1 RNA binding protein US11 is a virion component and associates with ribosomal 60s subunits. J. Virol. 66:3624-3632.
41. Schang, L. M., J. Phillips, and P. A. Schaffer. 1998. Requirement for cellular cyclin-depcndent kinases in herpes simplex virus replication and transcription. J. Virol. 72:5626-5637.
42. Schang, L. M., A. Rosenberg, and P. A. Schaffer. 1999. Transcription of herpes simplex virus immediate-early and early genes is inhibited by roscovitine, an inhibitor specific for cellular cyclin-dependent kinases. J. Virol. 73:2161-2172.
43. Sherr, C. J. 1994. Gil phase progression: cycling on cue. Cell 79:551-555.
44. Van Sant, C., V. Kawaguchi, and B. Roizman. 1999. A single amino acid substitution in the cyclin D binding domain of the infected cell protein no. 0 abrogates the neuroinvasiveness of herpes simplex virus without affecting its ability to replicate. Proc. Natl. Acad Sci. USA 96:8184-8189.
45. Wilcock, D., and D. P. Lane. 1991. Localization of p53, retinoblastoma and host replication proteins at sites of viral replication in herpes-infected cell. Nature 349:429-431.
46. Yu, L., L. Orlandi, P. Wang, M. S. Orr, A. M. Senderowicz, E. A. Sausville, R. Silvestrini, N. Watanabe, H. Piwnica-Worms, and P. M. O'Connor. 1998. UCN-01 abrogates G2 arrest through a cdc2-dependent pathway that is associated with inactivation of the weelhu kinase and activation of the cdc25C phosphatase. J. Biol. Chem. 273:33455-33464.
47. Zeng, Y., K. C. Forbes, Z. Wu, S. Moreno, H. Piwnica-Worms, and T. Enoch. 1998. Replication Checkpoint requires phosphorylution of the phosphatase cdc25C by cds or chkl. Nature 395:507-510.