Macrophage Elovl6 deficiency ameliorates foam cell formation and reduces atherosclerosis in low-density lipoprotein receptor-deficient mice

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 31, Issue 9, 2011, Pages 1973-1979

  Saito, Ryo ^a   Matsuzaka, Takashi ^a   Karasawa, Tadayoshi ^a   Sekiya, Motohiro ^b   Okada, Nazuki ^a   Igarashi, Masaki ^b   Matsumori, Rie ^a   Ishii, Kiyoaki ^a   Nakagawa, Yoshimi ^a   Iwasaki, Hitoshi ^a   Kobayashi, Kazuto ^a   Yatoh, Shigeru ^a   Takahashi, Akimitsu ^a   Sone, Hirohito ^a   Suzuki, Hiroaki ^a   Yahagi, Naoya ^a   Yamada, Nobuhiro ^a   Shimano, Hitoshi ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

atherosclerosis; Elovl6; fatty acid composition; macrophage

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ACETYL LOW DENSITY LIPOPROTEIN; ACYL COENZYME A DESATURASE; CHEMOKINE RECEPTOR CCR2; CHOLESTEROL; CHOLESTEROL ESTER; ELONGATION OF VERY LONG CHAIN FATTY ACID FAMILY MEMBER 6 PROTEIN; ENZYME; FATTY ACID; FATTY ACID SYNTHASE; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN RECEPTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOUNSATURATED FATTY ACID; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; PHOSPHOLIPID; SHORT CHAIN FATTY ACID; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ATHEROSCLEROSIS; ARTICLE; ATHEROSCLEROSIS; BONE MARROW CELL; CELL INFILTRATION; CHOLESTEROL INTAKE; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; DISEASE PREDISPOSITION; FAT INTAKE; FOAM CELL; HEMATOLOGICAL PARAMETERS; LIPID COMPOSITION; LIPID STORAGE; MACROPHAGE; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE;

ACETYLTRANSFERASES; ANIMALS; ATHEROSCLEROSIS; CHOLESTEROL; CHOLESTEROL ESTERS; FATTY ACIDS; FOAM CELLS; LIPID METABOLISM; MACROPHAGES; MICE; MICE, INBRED C57BL; RECEPTORS, LDL;

EID: 80052156697     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.110.221663     Document Type: Article

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