Transcriptomic signatures of alterations in a myoblast cell line infected with four distinct strains of Trypanosoma cruzi

American Journal of Tropical Medicine and Hygiene

Volumn 82, Issue 5, 2010, Pages 846-854

  Adesse, Daniel ^a   Garzoni, Luciana Ribeiro ^a   Meirelles, Maria De Nazareth ^a   Iacobas, Dumitru A ^b   Iacobas, Sanda ^b   Spray, David C ^b   Tanowitz, Herbert B ^b  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA MICROARRAY; GENE EXPRESSION; HOST PARASITE INTERACTION; MYOBLAST; NONHUMAN; RAT; STRAIN DIFFERENCE; TRANSCRIPTOMICS; TRYPANOSOMA CRUZI;

ANIMALS; CELL LINE; GENE EXPRESSION PROFILING; HUMANS; MYOBLASTS; RATS; TRANSCRIPTION, GENETIC; TRYPANOSOMA CRUZI;

RATTUS; TRYPANOSOMA CRUZI;

EID: 77952737414     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.2010.09-0399     Document Type: Article

References (27)

1. de Souza W, 2007. Chagas' disease: facts and reality. Microbes Infect 9: 544-545.
2. Tanowitz HB, Kirchhoff LV, Simon D, Morris SA, Weiss LM, Wittner M, 1992. Chagas' disease. Clin Microbiol Rev 5: 400-419.
3. Higuchi Mde L, Benvenuti LA, Martins Reis M, Metzger M, 2003. Pathophysiology of the heart in Chagas' disease: current status and new developments. Cardiovasc Res 60: 96-107. (Pubitemid 38373480)
4. Carneiro M, Romanha AJ, Chiari E, 1991. Biological characterization of Trypanosoma cruzi strains from different zymodemes and schizodemes. Mem Inst Oswaldo Cruz 86: 387-393.
5. Andrade SG, 1999. Trypanosoma cruzi: clonal structure of parasite strains and the importance of principal clones. Mem Inst Oswaldo Cruz 94 (Suppl 1): 185-187.
6. Andrade SG, Magalhães JB, 1996. Biodemes and zymodemes of Trypanosoma cruzi strains: correlations with clinical data and experimental pathology. Rev Soc Bras Med Trop 30: 27-35.
7. Veloso VM, Carneiro CM, Toledo MJ, Lana M, Chiari E, Tafuri WL, Bahia MT, 2001. Variation in susceptibility to benznidazole in isolates derived from Trypanosoma cruzi parental strains. Mem Inst Oswaldo Cruz 96: 1005-1011. (Pubitemid 33643308)
8. Mielniczki-Pereira AA, Chiavegatto CM, López JA, Colli W, Alves MJ, Gadelha FR, 2007. Trypanosoma cruzi strains, Tulahuen 2 and Y, besides the difference in resistance to oxidative stress, display differential glucose-6-phosphate and 6-phosphogluconate dehydrogenases activities. Acta Trop 101: 54-60. (Pubitemid 46198791)
9. Sanchez G, Wallace A, Olivares M, Diaz N, Aguilera X, Apt W, Solari A, 1990. Biological characterization of Trypanosoma cruzi zymodemes: in vitro differentiation of epimastigotes and infectivity of culture metacyclic trypomastigotes to mice. Exp Parasitol 71: 125-133. (Pubitemid 20324000)
10. Shigihara T, Hashimoto M, Shindo N, Aoki T, 2008. Transcriptome profile of Trypanosoma cruzi-infected cells: simultaneous up- and down-regulation of proliferation inhibitors and promoters. Parasitol Res 102: 715-722.
11. Imai K, Mimori T, Kawai M, Koga H, 2005. Microarray analysis of host gene-expression during intracellular nests formation of Trypanosoma cruzi amastigotes. Microbiol Immunol 49: 623-631. (Pubitemid 41289348)
12. Mukherjee S, Belbin TJ, Spray DC, Iacobas DA, Weiss LM, Kitsis RN, Wittner M, Jelicks LA, Scherer PE, Ding A, Tanowitz HB, 2003. Microarray analysis of changes in gene expression in a murine model of chronic chagasic cardiomyopathy. Parasitol Res 91: 187-196. (Pubitemid 37260442)
13. Mukherjee S, Nagajyothi F, Mukhopadhyay A, Machado FS, Belbin TJ, Campos de Carvalho A, Guan F, Albanese C, Jelicks LA, Lisanti MP, Silva JS, Spray DC, Weiss LM, Tanowitz HB, 2008. Alterations in myocardial gene expression associated with experimental Trypanosoma cruzi infection. Genomics 91: 423-432.
14. Garg N, Popov VL, Papaconstantinou J, 2003. Profiling gene transcription reveals a deficiency of mitochondrial oxidative phosphorylation in Trypanosoma cruzi-infected murine hearts: implications in chagasic myocarditis development. Biochim Biophys Acta 1638: 106-120. (Pubitemid 36829268)
15. Rowin KS, Tanowitz HB, Wittner M, Nguyen HT, Nadal-Ginard B, 1983. Inhibition of muscle differentiation by Trypanosoma cruzi. Proc Natl Acad Sci USA 80: 6390-6394. (Pubitemid 14243425)
16. Bertelli MS, Brener Z, 1980. Infection of tissue culture cells with bloodstream trypomastigotes of Trypanosoma cruzi. J Parasitol 66: 992-997. (Pubitemid 11081617)
17. Fernandes O, Santos SS, Cupolillo E, Mendonça B, Derre R, Junqueira AC, Santos LC, Sturm NR, Naiff RD, Barret TV, Campbell DA, Coura JR, 2001. A mini-exon multiplex polymerase chain reaction to distinguish the major groups of Trypanosoma cruzi and T. rangeli in the Brazilian Amazon. Trans R Soc Trop Med Hyg 95: 97-99. (Pubitemid 34202239)
18. Garzoni LR, Caldera A, Meirelles Mde N, de Castro SL, Docampo R, Meints GA, Oldfield E, Urbina JA, 2004. Selective in vitro effects of the farnesyl pyrophosphate synthase inhibitor risedronate on Trypanosoma cruzi. Int J Antimicrob Agents 23: 273-285. (Pubitemid 38283597)
19. Iacobas DA, Iacobas S, Li WE, Zoidl G, Dermietzel R, Spray DC, 2005. Genes controlling multiple functional pathways are transcriptionally regulated in connexin43 null mouse heart. Physiol Genomics 20: 211-223. (Pubitemid 40388521)
20. Iacobas DA, Fan C, Iacobas S, Spray DC, Haddad GG, 2006 Transcriptomic changes in developing kidney exposed to chronic hypoxia. Biochem Biophys Res Commun 13: 329-338. (Pubitemid 44339630)
21. Combs TP, Nagajyothi F, Mukherjee S, de Almeida CJ, Jelicks LA, Schubert W, Lin Y, Jayabalan DS, Zhao D, Braunstein VL, Landskroner-Eiger S, Cordero A, Factor SM, Weiss LM, Lisanti MP, Tanowitz HB, Scherer PE, 2005. The adipocyte as an important target cell for Trypanosoma cruzi infection. J Biol Chem 24: 24085-24094. (Pubitemid 40884896)
22. Miles MA, Cedillos RA, Póvoa MM, de Souza AA, Prata A, Macedo V, 1981 Do radically dissimilar Trypanosoma cruzi strains (zymodemes) cause Venezuelan and Brazilian forms of Chagas' disease? Lancet 20: 1338-1340.
23. Adesse D, Garzoni LR, Huang H, Tanowitz HB, de Nazareth Meirelles M, Spray DC, 2008. Trypanosoma cruzi induces changes in cardiac connexin43 expression. Microbes Infect 10: 21-28.
24. de Melo TG, Meirelles Mde N, Pereira MC, 2008. Trypanosoma cruzi alters adherens junctions in cardiomyocytes. Microbes Infect 10: 1405-1410.
25. Saffitz JE, Hames KY, Kanno S, 2007. Remodeling of gap junctions in ischemic and nonischemic forms of heart disease. J Membr Biol 218: 65-71. (Pubitemid 350132117)
26. Celes MR, Torres-Dueñas D, Alves-Filho JC, Duarte DB, Cunha FQ, Rossi MA, 2007. Reduction of gap and adherens junction proteins and intercalated disc structural remodeling in the hearts of mice submitted to severe cecal ligation and puncture sepsis. Crit Care Med 35: 2176-2185. (Pubitemid 47326457)
27. Spray DC, Tanowitz HB, 2007. Pathology of mechanical and gap junctional co-coupling at the intercalated disc: is sepsis a junctionopathy? Crit Care Med 35: 2231-2232.