Differential gene expression following ionizing radiation in multicellular spheroid depending on p53 status: Identification of potential targets and prediction of responsive signaling pathways

Biochip Journal

Volumn 5, Issue 3, 2011, Pages 280-288

  Kwon, Jee Young ^a,b   Seo, Young Rok ^a,b  

^a Dongguk University   (South Korea)

^b Kyung Hee University Hospital   (South Korea)

Author keywords

Apoptosis; Ionizing radiation (IR); Multicellular spheroid (MCS); p53; Radioresistance

Indexed keywords

CELL CULTURE; CELL DEATH; GENE THERAPY; IONIZING RADIATION; MONOLAYERS; RADIATION SHIELDING; RADIOACTIVITY; SIGNALING; THREE DIMENSIONAL;

CANCER CELLS; CARCINOMA CELLS; CELL MIGRATION; CELL SURVIVAL; CELLULAR RESPONSE; COMPLEX RESPONSE; CULTURE SYSTEMS; DIFFERENTIAL GENE EXPRESSIONS; GENE EXPRESSION PATTERNS; HUMAN CARCINOMA CELLS; IN-SITU STUDY; IN-VIVO; MOLECULAR NETWORKS; MOLECULAR RESPONSE; MOLECULAR TARGETS; MONOLAYER CELLS; MONOLAYER CULTURE; MULTICELLULAR SPHEROID; NULL TYPE; P53; RADIORESISTANCE; SIGNALING PATHWAYS; SOLID TUMORS; TARGET MOLECULE; TRANSCRIPT LEVEL; WILD TYPES;

GENE EXPRESSION;

PROTEIN P53;

ANXA11 GENE; APOPTOSIS; ARTICLE; C2 GENE; CANCER CELL CULTURE; CANCER RADIOTHERAPY; CELL STRAIN HCT116; CELL SURVIVAL; CONTROLLED STUDY; GENE; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; HUMAN; HUMAN CELL; IONIZING RADIATION; KCNE2 GENE; KIF3C GENE; MICROARRAY ANALYSIS; MSH5 GENE; MULTICELLULAR SPHEROID; NUCLEOTIDE SEQUENCE; OSCAR GENE; PHENOTYPE; RADIOSENSITIVITY; SIGNAL TRANSDUCTION; SURVIVAL RATE; WILD TYPE;

EID: 80052138399     PISSN: 19760280     EISSN: 20927843     Source Type: Journal    
DOI: 10.1007/s13206-011-5313-y     Document Type: Article

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