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Volumn 301, Issue 3, 2011, Pages

Developmental exposure to di(2-ethylhexyl) phthalate impairs endocrine pancreas and leads to long-term adverse effects on glucose homeostasis in the rat

Author keywords

cells; Insulin secretion

Indexed keywords

GLUCOSE; INSULIN; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER;

EID: 80052068415     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00233.2011     Document Type: Article
Times cited : (147)

References (42)
  • 2
    • 0027529974 scopus 로고
    • Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): Relation to reduced fetal growth
    • Barker DJ, Hales CN, Fall CH, Osmond C, Phipps K, Clark PM. Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth. Diabetologia 36: 62-67, 1993.
    • (1993) Diabetologia , vol.36 , pp. 62-67
    • Barker, D.J.1    Hales, C.N.2    Fall, C.H.3    Osmond, C.4    Phipps, K.5    Clark, P.M.6
  • 4
    • 43349101355 scopus 로고    scopus 로고
    • Increased pancreatic beta-cell apoptosis following fetal and neonatal exposure to nicotine is mediated via the mitochondria
    • Bruin JE, Gerstein HC, Morrison KM, Holloway AC. Increased pancreatic beta-cell apoptosis following fetal and neonatal exposure to nicotine is mediated via the mitochondria. Toxicol Sci 103: 362-370, 2008.
    • (2008) Toxicol Sci , vol.103 , pp. 362-370
    • Bruin, J.E.1    Gerstein, H.C.2    Morrison, K.M.3    Holloway, A.C.4
  • 5
    • 3242885420 scopus 로고    scopus 로고
    • Exposure to di-(2-ethylhexyl) phthalate among premature neonates in a neonatal intensive care unit
    • Calafat AM, Needham LL, Silva MJ, Lambert G. Exposure to di-(2-ethylhexyl) phthalate among premature neonates in a neonatal intensive care unit. Pediatrics 113: e429-e434, 2004.
    • (2004) Pediatrics , vol.113
    • Calafat, A.M.1    Needham, L.L.2    Silva, M.J.3    Lambert, G.4
  • 7
    • 79951805682 scopus 로고    scopus 로고
    • Endocrine disruptors: From endocrine to metabolic disruption
    • Casals-Casas C, Desvergne B. Endocrine disruptors: from endocrine to metabolic disruption. Annu Rev Physiol 73: 135-162, 2010.
    • (2010) Annu Rev Physiol , vol.73 , pp. 135-162
    • Casals-Casas, C.1    Desvergne, B.2
  • 10
    • 77956488453 scopus 로고    scopus 로고
    • Perinatal exposure to di-(2-ethylhexyl) phthalate leads to restricted growth and delayed lung maturation in newborn rats
    • Chen SQ, Chen JN, Cai XH, Chen GR, Gao Y, Ge RS, Wu HS, Lin ZL, Lin J. Perinatal exposure to di-(2-ethylhexyl) phthalate leads to restricted growth and delayed lung maturation in newborn rats. J Perinat Med 38: 515-521, 2010.
    • (2010) J Perinat Med , vol.38 , pp. 515-521
    • Chen, S.Q.1    Chen, J.N.2    Cai, X.H.3    Chen, G.R.4    Gao, Y.5    Ge, R.S.6    Wu, H.S.7    Lin, Z.L.8    Lin, J.9
  • 12
    • 80052044536 scopus 로고    scopus 로고
    • EPA. Integrated Risk Information System, Office of Research and Development, US Environmental Protection Agency, Washington, DC: National Center For Environmental Assessment
    • EPA. Integrated Risk Information System (IRIS) on Di(2-ethylhexyl) phthalate. Washington, DC: National Center for Environmental Assessment, Office of Research and Development, US Environmental Protection Agency, 1999.
    • (1999) IRIS) On Di(2-ethylhexyl) Phthalate
  • 14
    • 0031873342 scopus 로고    scopus 로고
    • Beta-cell mass and proliferation following late fetal and early postnatal malnutrition in the rat
    • Garofano A, Czernichow P, Breant B. Beta-cell mass and proliferation following late fetal and early postnatal malnutrition in the rat. Diabetologia 41: 1114-1120, 1998.
    • (1998) Diabetologia , vol.41 , pp. 1114-1120
    • Garofano, A.1    Czernichow, P.2    Breant, B.3
  • 15
    • 3843101644 scopus 로고    scopus 로고
    • Oligonucleotide microarray analysis reveals PDX1 as an essential regulator of mitochondrial metabolism in rat islets
    • Gauthier BR, Brun T, Sarret EJ, Ishihara H, Schaad O, Descombes P, Wollheim CB. Oligonucleotide microarray analysis reveals PDX1 as an essential regulator of mitochondrial metabolism in rat islets. J Biol Chem 279: 31121-31130, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 31121-31130
    • Gauthier, B.R.1    Brun, T.2    Sarret, E.J.3    Ishihara, H.4    Schaad, O.5    Descombes, P.6    Wollheim, C.B.7
  • 16
    • 2442528657 scopus 로고    scopus 로고
    • Changes in some hormones by low doses of di (2-ethyl hexyl) phthalate (DEHP), a commonly used plasticizer in PVC blood storage bags & medical tubing
    • Gayathri NS, Dhanya CR, Indu AR, Kurup PA. Changes in some hormones by low doses of di (2-ethyl hexyl) phthalate (DEHP), a commonly used plasticizer in PVC blood storage bags & medical tubing. Indian J Med Res 119: 139-144, 2004.
    • (2004) Indian J Med Res , vol.119 , pp. 139-144
    • Gayathri, N.S.1    Dhanya, C.R.2    Indu, A.R.3    Kurup, P.A.4
  • 17
    • 25844472682 scopus 로고    scopus 로고
    • Use of di(2-ethylhexyl) phthalate-containing medical products and urinary levels of mono(2-ethylhexyl) phthalate in neonatal intensive care unit infants
    • Green R, Hauser R, Calafat AM, Weuve J, Schettler T, Ringer S, Huttner K, Hu H. Use of di(2-ethylhexyl) phthalate-containing medical products and urinary levels of mono(2-ethylhexyl) phthalate in neonatal intensive care unit infants. Environ Health Perspect 113: 1222-1225, 2005.
    • (2005) Environ Health Perspect , vol.113 , pp. 1222-1225
    • Green, R.1    Hauser, R.2    Calafat, A.M.3    Weuve, J.4    Schettler, T.5    Ringer, S.6    Huttner, K.7    Hu, H.8
  • 18
    • 0036895383 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and the development of diabetes: A review
    • Harding HP, Ron D. Endoplasmic reticulum stress and the development of diabetes: a review. Diabetes 51, Suppl 3: S455-S461, 2002.
    • (2002) Diabetes , vol.51 , Issue.SUPPL. 3
    • Harding, H.P.1    Ron, D.2
  • 21
    • 51949106158 scopus 로고    scopus 로고
    • Association of urinary bisphenol A concentration with medical disorders and laboratory abnormalities in adults
    • Lang IA, Galloway TS, Scarlett A, Henley WE, Depledge M, Wallace RB, Melzer D. Association of urinary bisphenol A concentration with medical disorders and laboratory abnormalities in adults. JAMA 300: 1303-1310, 2008.
    • (2008) JAMA , vol.300 , pp. 1303-1310
    • Lang, I.A.1    Galloway, T.S.2    Scarlett, A.3    Henley, W.E.4    Depledge, M.5    Wallace, R.B.6    Melzer, D.7
  • 22
  • 23
    • 33748764640 scopus 로고    scopus 로고
    • Dietary di(2-ethylhexyl) phthalate-impaired glucose metabolism in experimental animals
    • Martinelli MI, Mocchiutti NO, Bernal CA. Dietary di(2-ethylhexyl) phthalate-impaired glucose metabolism in experimental animals. Hum Exp Toxicol 25: 531-538, 2006.
    • (2006) Hum Exp Toxicol , vol.25 , pp. 531-538
    • Martinelli, M.I.1    Mocchiutti, N.O.2    Bernal, C.A.3
  • 24
    • 0018956788 scopus 로고
    • Effect of di-2-ethylhexyl phthalate (DEHP) on glycogen metabolism in rat liver
    • Mushtaq M, Srivastava SP, Seth PK. Effect of di-2-ethylhexyl phthalate (DEHP) on glycogen metabolism in rat liver. Toxicology 16: 153-161, 1980.
    • (1980) Toxicology , vol.16 , pp. 153-161
    • Mushtaq, M.1    Srivastava, S.P.2    Seth, P.K.3
  • 25
    • 0036022403 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress-mediated apoptosis in pancreatic beta-cells
    • Oyadomari S, Araki E, Mori M. Endoplasmic reticulum stress-mediated apoptosis in pancreatic beta-cells. Apoptosis 7: 335-345, 2002.
    • (2002) Apoptosis , vol.7 , pp. 335-345
    • Oyadomari, S.1    Araki, E.2    Mori, M.3
  • 27
    • 77953675715 scopus 로고    scopus 로고
    • Relationship between serum concentrations of organochlorine pesticides and metabolic syndrome among non-diabetic adults
    • Park SK, Son HK, Lee SK, Kang JH, Chang YS, Jacobs DR, Lee DH. Relationship between serum concentrations of organochlorine pesticides and metabolic syndrome among non-diabetic adults. J Prev Med Public Health 43: 1-8, 2010.
    • (2010) J Prev Med Public Health , vol.43 , pp. 1-8
    • Park, S.K.1    Son, H.K.2    Lee, S.K.3    Kang, J.H.4    Chang, Y.S.5    Jacobs, D.R.6    Lee, D.H.7
  • 28
    • 80052070958 scopus 로고    scopus 로고
    • Consolidated Final Report
    • RARE. EU-Risk Assessment of Bis(2-ethylhexyl) Phthalate (DEHP)
    • RARE. EU-Risk Assessment of Bis(2-ethylhexyl) Phthalate (DEHP). Consolidated Final Report. European Union Risk Assessment Report (RARE), 2005.
    • (2005) European Union Risk Assessment Report (RARE)
  • 32
    • 47949127583 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress-induced activation of activating transcription factor 6 decreases insulin gene expression via up-regulation of orphan nuclear receptor small heterodimer partner
    • Seo HY, Kim YD, Lee KM, Min AK, Kim MK, Kim HS, Won KC, Park JY, Lee KU, Choi HS, Park KG, Lee IK. Endoplasmic reticulum stress-induced activation of activating transcription factor 6 decreases insulin gene expression via up-regulation of orphan nuclear receptor small heterodimer partner. Endocrinology 149: 3832-3841, 2008.
    • (2008) Endocrinology , vol.149 , pp. 3832-3841
    • Seo, H.Y.1    Kim, Y.D.2    Lee, K.M.3    Min, A.K.4    Kim, M.K.5    Kim, H.S.6    Won, K.C.7    Park, J.Y.8    Lee, K.U.9    Choi, H.S.10    Park, K.G.11    Lee, I.K.12
  • 34
    • 0035489035 scopus 로고    scopus 로고
    • Intrauterine growth retardation leads to the development of type 2 diabetes in the rat
    • Simmons RA, Templeton LJ, Gertz SJ. Intrauterine growth retardation leads to the development of type 2 diabetes in the rat. Diabetes 50: 2279-2286, 2001.
    • (2001) Diabetes , vol.50 , pp. 2279-2286
    • Simmons, R.A.1    Templeton, L.J.2    Gertz, S.J.3
  • 35
    • 0016818804 scopus 로고
    • Maternal-fetal transfer of 14C-di-2-ethylhexyl phthalate and 14C-diethyl phthalate in rats
    • Singh AR, Lawrence WH, Autian J. Maternal-fetal transfer of 14C-di-2-ethylhexyl phthalate and 14C-diethyl phthalate in rats. J Pharm Sci 64: 1347-1350, 1975.
    • (1975) J Pharm Sci , vol.64 , pp. 1347-1350
    • Singh, A.R.1    Lawrence, W.H.2    Autian, J.3
  • 36
    • 57349197879 scopus 로고    scopus 로고
    • Prenatal nicotine exposure alters early pancreatic islet and adipose tissue development with consequences on the control of body weight and glucose metabolism later in life
    • Somm E, Schwitzgebel VM, Vauthay DM, Camm EJ, Chen CY, Giacobino JP, Sizonenko SV, Aubert ML, Huppi PS. Prenatal nicotine exposure alters early pancreatic islet and adipose tissue development with consequences on the control of body weight and glucose metabolism later in life. Endocrinology 149: 6289-6299, 2008.
    • (2008) Endocrinology , vol.149 , pp. 6289-6299
    • Somm, E.1    Schwitzgebel, V.M.2    Vauthay, D.M.3    Camm, E.J.4    Chen, C.Y.5    Giacobino, J.P.6    Sizonenko, S.V.7    Aubert, M.L.8    Huppi, P.S.9
  • 37
    • 34250184495 scopus 로고    scopus 로고
    • Concentrations of urinary phthalate metabolites are associated with increased waist circumference and insulin resistance in adult U.S. males
    • Stahlhut RW, van Wijngaarden E, Dye TD, Cook S, Swan SH. Concentrations of urinary phthalate metabolites are associated with increased waist circumference and insulin resistance in adult U.S. males. Environ Health Perspect 115: 876-882, 2007.
    • (2007) Environ Health Perspect , vol.115 , pp. 876-882
    • Stahlhut, R.W.1    van Wijngaarden, E.2    Dye, T.D.3    Cook, S.4    Swan, S.H.5
  • 38
    • 67349150270 scopus 로고    scopus 로고
    • Fetal and neonatal exposure to three typical environmental chemicals with different mechanisms of action: Mixed exposure to phenol, phthalate, and dioxin cancels the effects of sole exposure on mouse midbrain dopaminergic nuclei
    • Tanida T, Warita K, Ishihara K, Fukui S, Mitsuhashi T, Sugawara T, Tabuchi Y, Nanmori T, Qi WM, Inamoto T, Yokoyama T, Kitagawa H, Hoshi N. Fetal and neonatal exposure to three typical environmental chemicals with different mechanisms of action: mixed exposure to phenol, phthalate, and dioxin cancels the effects of sole exposure on mouse midbrain dopaminergic nuclei. Toxicol Lett 189: 40-47, 2009.
    • (2009) Toxicol Lett , vol.189 , pp. 40-47
    • Tanida, T.1    Warita, K.2    Ishihara, K.3    Fukui, S.4    Mitsuhashi, T.5    Sugawara, T.6    Tabuchi, Y.7    Nanmori, T.8    Qi, W.M.9    Inamoto, T.10    Yokoyama, T.11    Kitagawa, H.12    Hoshi, N.13
  • 42
    • 49649087003 scopus 로고    scopus 로고
    • Increased risk of diabetes and polychlorinated biphenyls and dioxins: A 24-year follow-up study of the Yucheng cohort
    • Wang SL, Tsai PC, Yang CY, Leon Guo Y. Increased risk of diabetes and polychlorinated biphenyls and dioxins: a 24-year follow-up study of the Yucheng cohort. Diabetes Care 31: 1574-1579, 2008.
    • (2008) Diabetes Care , vol.31 , pp. 1574-1579
    • Wang, S.L.1    Tsai, P.C.2    Yang, C.Y.3    Leon Guo, Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.