Gap junctions and hydrogen peroxide are involved in endothelium-derived hyperpolarising responses to bradykinin in omental arteries and veins isolated from pregnant women

European Journal of Pharmacology

Volumn 668, Issue 1-2, 2011, Pages 225-232

  Hammond, Stephanie ^a   Mathewson, Alastair M ^a   Baker, Philip N ^b   Mayhew, Terry M ^a   Dunn, William R ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Connexin; EDHF; Endothelium; Gap junctions; H 2O 2; Pregnancy

Indexed keywords

BRADYKININ; CARBENOXOLONE; CATALASE; CONNEXIN 37; CONNEXIN 40; CONNEXIN 43; HYDROGEN PEROXIDE;

ARTERY; ARTERY DILATATION; ARTERY MEDIA; ARTICLE; CESAREAN SECTION; CONTROLLED STUDY; ELECTROMYOGRAPHY; FEMALE; GAP JUNCTION; HEART MUSCLE FIBER MEMBRANE STEADY POTENTIAL; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; OMENTUM ARTERY; OMENTUM VEIN; PREGNANCY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; VASCULAR ENDOTHELIUM; VEIN; VEIN DILATATION;

ARTERIES; BRADYKININ; CATALASE; ENDOTHELIUM, VASCULAR; FEMALE; GAP JUNCTIONS; HUMANS; HYDROGEN PEROXIDE; NG-NITROARGININE METHYL ESTER; OMENTUM; PREGNANCY; VASODILATION; VEINS;

EID: 80052046932     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.06.050     Document Type: Article

References (35)

1. E. Bussemaker, R. Popp, J. Binder, R. Busse, and I. Fleming Characterization of the endothelium-derived hyperpolarizing factor (EDHF) response in the human interlobular artery Kidney Int. 63 2003 1749 1755 (Pubitemid 36513320)
2. N.H. Buus, U. Simonsen, H.K. Pilegaard, and M.J. Mulvany Nitric oxide, prostanoid and non-NO, non-prostanoid involvement in acetylcholine relaxation of isolated human small arteries Br. J. Pharmacol. 129 2000 184 192 (Pubitemid 30072686)
3. W.B. Campbell, D. Gebremedhin, P.F. Pratt, and D.R. Harder Identification of epoxy-eicosatrienoic acids as endothelium-derived hyperpolarizing factors Circ. Res. 78 1996 415 423 (Pubitemid 26072547)
4. A.T. Chaytor, W.H. Evans, and T.M. Griffith Central role of heterocellular gap junctional communication in endothelium-dependent relaxations of rabbit arteries J. Physiol. 508 1998 561 573 (Pubitemid 28203968)
5. P. Coats, F. Johnston, J. MacDonald, J.J. McMurray, and C. Hillier Endothelium-derived hyperpolarizing factor: identification and mechanisms of action in human subcutaneous resistance arteries Circulation 103 2001 1702 1708 (Pubitemid 32246620)
6. C. de Wit, B. Hoepfl, and S.E. Wölfle Endothelial mediators and communication through vascular gap junctions Biol. Chem. 387 2006 3 9 (Pubitemid 43089588)
7. + is an endothelium-derived hyperpolarizing factor in rat arteries Nature 396 1998 269 272 (Pubitemid 28541391)
8. S.M. Fitzgerald, B.K. Kemp-Harper, M. Tare, and H.C. Parkington Role of endothelium-derived hyperpolarizing factor in endothelial dysfunction during diabetes Clin. Exp. Pharmacol. Physiol. 32 2005 482 487 (Pubitemid 40780280)
9. T. Griffith Endothelium-dependent smooth muscle hyperpolarization: do gap junctions provide a unifying hypothesis? Br. J. Pharmacol. 141 2004 881 903 (Pubitemid 38510072)
10. O.A. Hatoum, D.G. Binion, H. Miura, G. Telford, M.F. Otterson, and D.D. Gutterman Role of hydrogen peroxide in ACh-induced dilation of human submucosal intestinal microvessels Am. J. Physiol. 288 2005 H48 H54
11. L.C. Kenny, P.N. Baker, D.A. Kendall, M.D. Randall, and W.R. Dunn Differential mechanisms of endothelium-dependent vasodilator responses in human myometrial small arteries in normal pregnancy and pre-eclampsia Clin. Sci. (Lond.) 103 2002 67 73 (Pubitemid 34729126)
12. L.C. Kenny, P.N. Baker, D.A. Kendall, M.D. Randall, and W.R. Dunn The role of gap junctions in mediating endothelium-dependent responses to bradykinin in myometrial small arteries isolated from pregnant women Br. J. Pharmacol. 136 2002 1085 1088 (Pubitemid 34970058)
13. G.A. Knock, and L. Poston Bradykinin-mediated relaxation of isolated maternal resistance arteries in normal pregnancy and preeclampsia Am. J. Obstet. Gynecol. 175 1996 1668 1674 (Pubitemid 27021045)
14. N.N. Lang, L. Luksha, D.E. Newby, and K. Kublickiene Connexin 43 mediates endothelium-derived hyperpolarising factor-induced vasodilatation in subcutaneous resistance arteries from healthy pregnant women Am. J. Physiol. 292 2007 H1026 H1032
15. X. Li, and J.M. Simard Connexin45 gap junction channels in rat cerebral vascular smooth muscle cells Am. J. Physiol. 281 2001 H1890 H1898
16. L. Luksha, H. Nisell, and K. Kublickiene The mechanism of EDHF-mediated responses in subcutaneous small arteries from healthy pregnant women Am. J. Physiol. 286 2004 R1102 R1109
17. L. Luksha, H. Nisell, N. Luksha, M. Kublickas, K. Hultenby, and K. Kublickiene Endothelium-derived hyperpolarizing factor in pre-eclampsia: heterogeneous contribution, mechanisms, and morphological prerequisites Am. J. Physiol. 294 2008 R510 R519
18. P.E.M. Martin, N.S. Hill, B. Kristensen, R.J. Errington, and T.M. Griffith Ouabain exerts biphasic effects on connexin functionality and expression in vascular smooth muscle cells Br. J. Pharmacol. 141 2004 374 384
19. S. Mather, K.A. Dora, S.L. Sandow, P. Winter, and C.J. Garland Rapid endothelial cell-selective loading of connexin 40 antibody blocks endothelium-derived hyperpolarizing factor dilation in rat small mesenteric arteries Circ. Res. 97 2005 399 407 (Pubitemid 41216145)
20. T. Matoba, H. Shimokawa, M. Nakishima, Y. Hirakawa, Y. Mukai, K. Hirano, H. Kanaide, and A. Takeshita Hydrogen peroxide is an endothelium-derived hyperpolarising factor in mice J. Clin. Invest. 106 2000 1521 1530 (Pubitemid 32040953)
21. T. Matoba, H. Shimokawa, H. Kubota, K. Morikawa, T. Fujiki, I. Kunihiro, Y. Mukai, Y. Hirakawa, and A. Takeshita Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in human mesenteric arteries Biochem. Biophys. Res. Commun. 290 2002 909 913 (Pubitemid 34687447)
22. C.A. McIntyre, C.H. Buckley, G.C. Jones, T.C. Sandeep, R.C. Andrews, A.I. Elliot, G.A. Gray, B.C. Williams, J.A. McKnight, B.R. Walker, and P.W. Hadoke Endothelium-derived hyperpolarizing factor and potassium use different mechanisms to induce relaxation of human subcutaneous resistance arteries Br. J. Pharmacol. 133 2001 902 908 (Pubitemid 32751800)
23. + channels Circ. Res. 83 1998 501 507 (Pubitemid 28411051)
24. H. Miura, J.J. Bosnjak, G. Ning, T. Saito, M. Miura, and D.D. Gutterman Role for hydrogen peroxide in flow-induced dilation of human coronary arterioles Circ. Res. 92 2003 e31 e40
25. M. Nakashima, J.V. Mombouli, A.A. Taylor, and P.M. Vanhoutte Endothelium-dependent hyperpolarization caused by bradykinin in human coronary arteries J. Clin. Invest. 92 1993 2867 2871 (Pubitemid 24006555)
26. P. Ohlmann, M.C. Martinez, F. Schneider, J.C. Stoclet, and R. Andriantsitohaina Characterization of endothelium-derived relaxing factors released by bradykinin in human resistance arteries Br. J. Pharmacol. 121 1997 657 664 (Pubitemid 27260767)
27. T. Okamoto, M. Akiyama, M. Takeda, E.C. Gabazza, T. Hayashi, and K. Suzuki Connexin32 is expressed in vascular endothelial cells and participates in gap-junction intercellular communication Biochem. Biophys. Res. Commun. 382 2009 264 268
28. I.F. Pascoal, and J.G. Umans Effect of pregnancy on mechanisms of relaxation in human omental microvessels Hypertension 28 1996 183 187 (Pubitemid 26322787)
29. I.F. Pascoal, M.D. Lindheimer, C. Nalbantian-Brandt, and J.G. Umans Preeclampsia selectively impairs endothelium-dependent relaxation and leads to oscillatory activity in small omental arteries J. Clin. Invest. 101 1998 464 470 (Pubitemid 28067344)
30. S. Sunano, H. Watanabe, S. Tanaka, F. Sekiguchi, and K. Shimmura Endothelium-derived relaxing, contracting and hyperpolarizing factors of mesenteric arteries of hypertensive and normotensive rats Br. J. Pharmacol. 126 1999 709 716 (Pubitemid 29087851)
31. Y. Suzuki, J. Kajikuri, K. Suzumori, and T. Itoh Mechanisms underlying the reduced endothelium-dependent relaxation in human omental resistance artery in pre-eclampsia J. Physiol. 527 2000 163 174 (Pubitemid 30649593)
32. Y. Suzuki, T. Hattori, J. Kajikuri, T. Yamamoto, K. Suzumori, and T. Itoh Reduced function of endothelial prostacyclin in human omental resistance arteries in pre-eclampsia J. Physiol. 545 2002 269 277 (Pubitemid 35386139)
33. L. Urakami-Harasawa, H. Shimokawa, M. Nakashima, K. Egashira, and A. Takeshita Importance of endothelium-derived hyperpolarizing factor in human arteries J. Clin. Invest. 100 1997 2793 2799 (Pubitemid 28007548)
34. S.M. Wallerstedt, and M. Bodelsson Endothelium-dependent relaxation by substance P in human isolated omental arteries and veins: relative contribution of prostanoids, nitric oxide and hyperpolarization Br. J. Pharmacol. 120 1997 25 30 (Pubitemid 27042556)
35. M. Wareing, J.E. Myers, M. O'Hara, L.C. Kenny, M.J. Taggart, L. Skillern, I. Machin, and P.N. Baker Phosphodiesterase-5 inhibitors and omental and placental small artery function in normal pregnancy and pre-eclampsia Eur. J. Obstet. Gynecol. Reprod. Biol. 127 2006 41 49 (Pubitemid 43947425)