Quercetin stimulates NGF-induced neurite outgrowth in PC12 cells via activation of Na/K + /2Cl - cotransporter

Cellular Physiology and Biochemistry

Volumn 28, Issue 1, 2011, Pages 147-156

  Nakajima, Ken Ichi ^a   Niisato, Naomi ^a,b   Marunaka, Yoshinori ^a,b  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b Takatsuki city   (Japan)

Author keywords

Chloride ion; Flavonoid; NKCC; Solute carrier

Indexed keywords

BUMETANIDE; CHLORIDE ION; NERVE GROWTH FACTOR; PROTEIN TYROSINE KINASE A; QUERCETIN; SMALL INTERFERING RNA; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; SODIUM POTASSIUM CHLORIDE COTRANSPORTER 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL STRAIN; DOSE RESPONSE; DRUG EFFECT; GENE SEQUENCE; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; RNA INTERFERENCE;

EID: 80051995530     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000331723     Document Type: Article

References (50)

1. Greene LA, Tischler AS: Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci USA 1976;73:2424-2428.
2. Nakajima K, Miyazaki H, Niisato N, Marunaka Y: Essential role of NKCC1 in NGF-induced neurite outgrowth. Biochem Biophys Res Commun 2007;359:604-610. (Pubitemid 46898993)
3. Nakajima K, Miyazaki H, Niisato N, Marunaka Y: Implication of chloride transporter, NKCC1, in neurite outgrowth. J Physiol Sci 2007;57:S121.
4. Niisato N, Eaton DC, Marunaka Y: Involvement of cytosolic Cl-in osmoregulation of ENaC gene expression. Am J Physiol Renal Physiol 2004;287:F932-939. (Pubitemid 39391090)
5. Menegazzi R, Busetto S, Dri P, Cramer R, Patriarca P: Chloride ion efflux regulates adherence, spreading, and respiratory burst of neutrophils stimulated by tumor necrosis factor-alpha (TNF) on biologic surfaces. J Cell Biol 1996;135:511-522. (Pubitemid 26359343)
6. Hebert SC, Mount DB, Gamba G: Molecular physiology of cation-coupled Cl-cotransport: the SLC12 family. Pflügers Arch 2004;447:580-593. (Pubitemid 38241442)
7. Mu C, Jia P, Yan Z, Liu X, Li X, Liu H: Quercetin induces cell cycle G1 arrest through elevating Cdk inhibitors p21 and p27 in human hepatoma cell line (HepG2). Methods Find Exp Clin Pharmacol 2007;29:179-183. (Pubitemid 46918296)
8. Kim YH, Lee DH, Jeong JH, Guo ZS, Lee YJ: Quercetin augments TRAIL-induced apoptotic death: involvement of the ERK signal transduction pathway. Biochem Pharmacol 2008;75:1946-1958.
9. Butelli E, Titta L, Giorgio M, Mock HP, Matros A, Peterek S, Schijlen EG, Hall RD, Bovy AG, Luo J, Martin C: Enrichment of tomato fruit with healthpromoting anthocyanins by expression of select transcription factors. Nature Biotechnol 2008;26:1301-1308.
10. Fujimoto S, Niisato N, Sugimoto T, Marunaka Y: Quercetin and NPPBinduced diminution of aldosterone action on Na+ absorption and ENaC expression in renal epithelium. Biochem Biophys Res Commun 2005;336:401-407. (Pubitemid 41267244)
11. Aoi W, Niisato N, Miyazaki H, Marunaka Y: Flavonoid-induced reduction of ENaC expression in the kidney of Dahl saltsensitive hypertensive rat. Biochem Biophys Res Commun 2004;315:892-896. (Pubitemid 38249387)
12. Niisato N, Nishino H, Nishio K, Marunaka Y: Cross talk of cAMP and flavone in regulation of cystic fibrosis transmembrane conductance regulator (CFTR) Cl-channel and Na+/K+/2Clcotransporter in renal epithelial A6 cells. Biochem Pharmacol 2004;67:795-801. (Pubitemid 38125264)
13. Niisato N, Ito Y, Marunaka Y: Activation of Cl-channel and Na+/K+/2Clcotransporter in renal epithelial A6 cells by flavonoids: genistein, daidzein, and apigenin. Biochem Biophys Res Commun 1999;254:368-371. (Pubitemid 29290406)
14. Asano J, Niisato N, Nakajima K, Miyazaki H, Yasuda M, Iwasaki Y, Hama T, Dejima K, Hisa Y, Marunaka Y: Quercetin stimulates Na+/K+/2Clcotransport via PTK-dependent mechanisms in human airway epithelium. Am J Respir Cell Mol Biol 2009;41:688-695.
15. Asano J, Niisato N, Yasuda M, Iwasaki Y, Hama T, Dejima K, Hisa Y, Marunaka Y: Quercetin stimulates NKCC via a PTKdependent mechanism in human airway epithelium. J Physiol Sci 2009;59:S295.
16. Lytle C, Xu JC, Biemesderfer D, Forbush B: Distribution and diversity of Na-K-Cl cotransport proteins: a study with monoclonal antibodies. Am J Physiol Cell Physiol 1995;269:C1496-1505.
17. Marshall CJ: Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 1995;80:179-185.
18. Nakajima K, Niisato N, Marunaka Y: Molecular mechanism of degradation and turnover of NKCC1. J Physiol Sci 2008;58:S205.
19. Erdogan A, Most AK, Wienecke B, Fehsecke A, Leckband C, Voss R, Grebe MT, Tillmanns H, Schaefer CA, Kuhlmann CR: Apigenin-induced nitric oxide production involves calciumactivated potassium channels and is responsible for antiangiogenic effects. J Thromb Haemost 2007;5:1774-1781. (Pubitemid 47091423)
20. Tomoda T, Aishima M, Takano N, Nakano T, Seki N, Yonemitsu Y, Sueishi K, Naito S, Ito Y, Teramoto N: The effects of flavoxate hydrochloride on voltage-dependent L-type Ca2+ currents in human urinary bladder. Br J Pharmacol 2005;146:25-32. (Pubitemid 43086091)
21. Keith CH: Neurite elongation is blocked if microtubule polymerization is inhibited in PC12 cells. Cell Motil Cytoskeleton 1990;17:95-105.
22. Yasui H, Katoh H, Yamaguchi Y, Aoki J, Fujita H, Mori K, Negishi M: Differential responses to nerve growth factor and epidermal growth factor in neurite outgrowth of PC12 cells are determined by Rac1 activation systems. J Biol Chem 2001;276:15298-15305.
23. Carmosino M, Gimenez I, Caplan M, Forbush B: Exon loss accounts for differential sorting of Na-K-Cl cotransporters in polarized epithelial cells. Mol Biol Cell 2008;19:4341-4351.
24. Del Castillo IC, Fedor-Chaiken M, Song JC, Starlinger V, Yoo J, Matlin KS, Matthews JB: Dynamic regulation of Na+-K+-2Cl-cotransporter surface expression by PKC-in Cl-secretory epithelia. Am J Physiol Cell Physiol 2005;289:C1332-1342.
25. Russell JM: Sodium-potassium-chloride cotransport. Physiol Rev 2000;80:211-276. (Pubitemid 30060565)
26. Anselmo AN, Earnest S, Chen W, Juang YC, Kim SC, Zhao Y, Cobb MH: WNK1 and OSR1 regulate the Na+, K+, 2Clcotransporter in HeLa cells. Proc Natl Acad Sci USA 2006;103:10883-10888.
27. Piechotta K, Garbarini N, England R, Delpire E: Characterization of the interaction of the stress kinase SPAK with the Na+-K+-2Cl-cotransporter in the nervous system: evidence for a scaffolding role of the kinase. J Biol Chem 2003;278:52848-52856. (Pubitemid 38035884)
28. Liedtke CM, Wang X, Smallwood ND: Role for protein phosphatase 2A in the regulation of Calu-3 epithelial Na+-K+-2Cl-, type 1 co-transport function. J Biol Chem 2005;280:25491-25498. (Pubitemid 40965547)
29. Jeon SB, Kim G, Kim JI, Seok YM, Kim SH, Suk K, Shin HM, Lee YH, Kim IK: Flavone inhibits vascular contraction by decreasing phosphorylation of the myosin phosphatase target subunit. Clin Exp Pharmacol Physiol 2007;34:1116-1120. (Pubitemid 47416344)
30. Gordon PB, Holen I, Seglen PO: Protection by naringin and some other flavonoids of hepatocytic autophagy and endocytosis against inhibition by okadaic acid. J Biol Chem 1995;270:5830-5838.
31. Jiang B, Hattori N, Liu B, Nakayama Y, Kitagawa K, Inagaki C: Suppression of cell proliferation with induction of p21 by Cl-channel blockers in human leukemic cells. Eur J Pharmacol 2004;488:27-34. (Pubitemid 38388520)
32. Jiang B, Hattori N, Liu B, Nakayama Y, Kitagawa K, Sumita K, Inagaki C: Expression and roles of Cl-channel ClC-5 in cell cycles of myeloid cells. Biochem Biophys Res Commun 2004;317:192-197. (Pubitemid 38401983)
33. Maki M, Miyazaki H, Nakajima K, Yamane J, Niisato N, Morihara T, Kubo T, Marunaka Y: Chloride-dependent acceleration of cell cycle via modulation of Rb and cdc2 in osteoblastic cells. Biochem Biophys Res Commun 2007;361:1038-1043. (Pubitemid 47259043)
34. Miyazaki H, Shiozaki A, Niisato N, Ohsawa R, Itoi H, Ueda Y, Otsuji E, Yamagishi H, Iwasaki Y, Nakano T, Nakahari T, Marunaka Y: Chloride ions control the G1/S cell-cycle checkpoint by regulating the expression of p21 through a p53-independent pathway in human gastric cancer cells. Biochem Biophys Res Commun 2008;366:506-512. (Pubitemid 50012763)
35. Hiraoka K, Miyazaki H, Miki T, Niisato N, Marunaka Y: Cell proliferation of prostatic cancer cell, LNCaP, is biphasically regulated by androgens. J Physiol Sci 2008;58:S207.
36. Hiraoka K, Miyazaki H, Niisato N, Iwasaki Y, Kawauchi A, Miki T, Marunaka Y: Chloride ion modulates cell proliferation of human androgenindependent prostatic cancer cell. Cell Physiol Biochem 2010;25:379-388.
37. Hiraoka K, Miyazaki H, Niisato N, Marunaka Y: Intracellular chloride regulates cell proliferation of androgenindependent prostate cancer PC3 cell. J Physiol Sci 2009;59:303.
38. Ohsawa R, Miyazaki H, Niisato N, Shiozaki A, Iwasaki Y, Otsuji E, Marunaka Y: Intracellular chloride regulates cell proliferation through the activation of stress-activated protein kinases in MKN28 human gastric cancer cells. J Cell Physiol 2010;223:764-770.
39. Ohsawa R, Miyazaki H, Otsuji E, Niisato N, Marunaka Y: Intracellular chloridedependent mechanism of stress-activated protein kinases in human gastric cancer MKN28 cells. J Physiol Sci 2009;59:303.
40. Ohsawa R, Miyazaki H, Shiozaki A, Otsuji E, Niisato N, Marunaka Y: Reduction of intracellular Cl-concentration induces the G1/S cell cycle arrest through the activation of stress-activated protein kinases in MKN28 human gastric cancer cells. J Physiol Sci 2008;58:S207.
41. Soroceanu L, Manning TJ, Sontheimer H: Modulation of glioma cell migration and invasion using Cl-and K+ ion channel blockers. J Neurosci 1999;19:5942-5954. (Pubitemid 29327929)
42. Ransom CB, O'Neal JT, Sontheimer H: Volume-activated chloride currents contribute to the resting conductance and invasive migration of human glioma cells. J Neurosci 2001;21:7674-7683. (Pubitemid 32904966)
43. Jeon S, Kim S, Kim E, Lee JE, Kim SJ, Juhnn YS, Kim YS, Bae CD, Park J: Chloride conductance is required for the protein kinase A and Rac1-dependent phosphorylation of moesin at Thr-558 by KCl in PC12 cells. J Biol Chem 2005;280:12181-12189.
44. Busetto S, Trevisan E, Decleva E, Dri P, Menegazzi R: Chloride movements in human neutrophils during phagocytosis: characterization and relationship to granule release. J Immunol 2007;179:4110-4124.
45. Marek L, Levresse V, Amura C, Zentrich E, Van Putten V, Nemenoff RA, Heasley LE: Multiple signaling conduits regulate global differentiation-specific gene expression in PC12 cells. J Cell Physiol 2004;201:459-469. (Pubitemid 39453131)
46. Vaudry D, Stork PJ, Lazarovici P, Eiden LE: Signaling pathways for PC12 cell differentiation: making the right connections. Science 2002;296:1648-1649. (Pubitemid 34579153)
47. Craig AM, Banker G: Neuronal polarity. Annu Rev Neurosci 1994;17:267-310. (Pubitemid 24117032)
48. Goldstein LS, Yang Z: Microtubule-based transport systems in neurons: the roles of kinesins and dyneins. Annu Rev Neurosci 2000;23:39-71. (Pubitemid 30350037)
49. Nakajima K, Niisato N, Marunaka Y: The role of chloride ion in dynamics of microtubule. J Physiol Sci 2009;59:350.
50. Nakajima T, Sugimoto T, Kurachi Y: Effects of anions on the G proteinmediated activation of the muscarinic K+ channel in the cardiac atrial cell membrane. Intracellular chloride inhibition of the GTPase activity of GK. J Gen Physiol 1992;99:665-682.