Divalent metal ion differentially regulates the sequential nicking reactions of the GIY-YIG homing endonuclease I-BMOI

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Kleinstiver, Benjamin P ^a   Bérubé Janzen, Wesley ^a   Fernandes, Andrew D ^a,b   Edgell, David R ^a  

^a WESTERN UNIVERSITY   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; DEOXYRIBONUCLEASE; DIVALENT METAL ION; GIY YIG HOMING ENDONUCLEASE I BMOL; HOMING ENDONUCLEASE; METAL ION; UNCLASSIFIED DRUG; DIVALENT CATION; I BMOI ENDONUCLEASE; I-BMOI ENDONUCLEASE; METAL;

ARTICLE; BASE PAIRING; CHEMICAL REACTION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DNA FOOTPRINTING; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVE SITE; ENZYME SUBSTRATE; GENE MUTATION; NONHUMAN; SEQUENTIAL NICKING REACTION; DRUG EFFECT; KINETICS; METABOLISM; SINGLE STRANDED DNA BREAK;

CATALYTIC DOMAIN; CATIONS, DIVALENT; DNA BREAKS, SINGLE-STRANDED; DNA FOOTPRINTING; ENDODEOXYRIBONUCLEASES; KINETICS; METALS;

EID: 80051953832     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023804     Document Type: Article

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