Anti-nuclear antibody reactivity in lupus may be partly hard-wired into the primary B-cell repertoire

Molecular Immunology

Volumn 46, Issue 16, 2009, Pages 3420-3426

  Chang, Sooghee ^a,b   Yang, Liu ^a   Moon, Young Mee ^b   Cho, Young Gyu ^b   Min, So Youn ^a,b   Kim, Tae Joo ^b   Kim, Young Joo ^b   Patrick, Wilson ^c   Kim, Ho Youn ^b   Mohan, Chandra ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b The Catholic University of Korea   (South Korea)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

Autoantibodies; Autoimmunity; B cells; Genetics; Immunoglobulin repertoire

Indexed keywords

ANTINUCLEAR ANTIBODY; ASPARTIC ACID; IMMUNOGLOBULIN HEAVY CHAIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIGEN BINDING; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; DNA BINDING; FEMALE; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; IMMUNOLOGICAL TOLERANCE; IMMUNOPATHOGENESIS; LUPUS VULGARIS; MALE; MOUSE; NONHUMAN; NUCLEOSOME; NUCLEOTIDE SEQUENCE; OVARY FOLLICLE CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN MOTIF; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; SOMATIC MUTATION; SPLEEN;

AMINO ACID MOTIFS; ANIMALS; ANTIBODIES, ANTINUCLEAR; ANTIBODIES, MONOCLONAL; ANTIGENS, LY; ANTIGENS, NUCLEAR; B-LYMPHOCYTES; DISEASE MODELS, ANIMAL; IMMUNOGLOBULIN HEAVY CHAINS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MICE; POLYMORPHISM, GENETIC;

ANAS; MUS;

EID: 70349446481     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2009.07.014     Document Type: Article

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