Role of Decreased Production of Interleukin-10 and Interferon-Gamma in Spontaneous Apoptosis of B-Chronic Lymphocytic Leukemia Lymphocytes In Vitro

Archives of Medical Research

Volumn 40, Issue 5, 2009, Pages 357-363

  Djurdjevic, Predrag ^a   Zelen, Ivanka ^a   Ristic, Petar ^a   Baskic, Dejan ^a,b   Popovic, Suzana ^a   Arsenijevic, Nebojsa ^a  

^a UNIVERSITY OF KRAGUJEVAC   (Serbia)

^b Public Health Institute   (Serbia)

Author keywords

Apoptosis; Chronic lymphocytic leukemia; Interferon gamma; Interleukin 10; Interleukin 4; Tumor necrosis factor alpha

Indexed keywords

ACRIDINE ORANGE; ETHIDIUM BROMIDE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 4; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CANCER STAGING; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IMMUNOPATHOGENESIS; IN VITRO STUDY; INCUBATION TIME; LYMPHOCYTE CULTURE; MALE; PROTEIN FUNCTION;

AGED; AGED, 80 AND OVER; APOPTOSIS; B-LYMPHOCYTES; FEMALE; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-10; INTERLEUKIN-4; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MALE; MIDDLE AGED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 70349187442     PISSN: 01884409     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.arcmed.2009.05.007     Document Type: Article

References (38)

1. Meinhardt G., Wendtner C.M., and Hallek M. Molecular pathogenesis of chronic lymphocytic leukemia: factors and signaling pathways regulating cell growth and survival. J Mol Med 77 (1999) 282-293
2. Jones D.T., Ganeshaguru K., Anderson R.J., et al. Albumin activates the AKT signaling pathway and protects B-chronic lymphocytic leukemia cells from chlorambucil- and radiation-induced apoptosis. Blood 101 (2003) 3174-3180
3. Secchiero P., Tiribelli M., Barbarotto E., et al. Aberrant expression of TRAIL in B chronic lymphocytic leukemia (B-CLL) cells. J Cell Physiol 205 (2005) 246-252
4. Neste E.V., Cardoen S., Offner F., et al. Old and new insights into the mechanism of action of two nucleoside analogs active in lymphoid malignancies: fludarabine and cladribine. Int J Oncol 27 (2005) 1113-1124
5. Djurdjevic P., Zelen I., Baskic D., et al. Apoptosis of peripheral blood lymphocytes in B-chronic lymphocytic leukemia patients. Med Čas 2 (2007) 7-18 (in Serbian)
6. Orsini E., Guarini A., and Foa R. Accessory cells, cytokine loops and cell-to-cell interactions in chronic lymphocytic leukemia. Rev Clin Exp Hematol 4 (2000) 73-98
7. Gallego A., Vargas J.A., Castejon R., et al. Production of intracellular IL-2, TNF-α, and IFN-γ by T cells in B-CLL. Cytometry B Clin Cytom 56 (2003) 23-29
8. Cheson B.D., Bennet J.M., Grever M., et al. National Cancer Institute-sponsored Working Group guidelines for clinical protocols for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment. Blood 87 (1996) 4990-4997
9. Binet J.L., Auquier A., Dighiero G., et al. A new prognostic classification of chronic lymphocytic leukemia derived from multivariate analysis. Cancer 48 (1981) 198-206
10. Kennedy L., and Reynolds J. Protocol for the removal of adherent macrophages. In: Lefkovits I. (Ed). Immunology Methods Manual (1997), Academic Press, San Diego 2091-2097
11. Baskic D., Popovic S., Ristic P., et al. Analysis of cycloheximide-induced apoptosis in human leukocytes: fluorescence microscopy using annexin V/propidium iodide versus acridine orange/ethidium bromide. Cell Biol Int 30 (2006) 924-932
12. Bran G.M., Stern-Straeter J., Hormann K., et al. Apoptosis in bone for tissue engineering. Arch Med Res 39 (2008) 467-482
13. Lagneaux L., Delforge A., Bron D., et al. Chronic lymphocytic leukemia B-cells but not normal B cells are rescued from apoptosis by contact with normal bone marrow stromal cells. Blood 91 (1998) 2387-2396
14. + cells subset in B-CLL patients correlates with stage of the disease. Eur J Haematol 72 (2004) 29-35
15. Fink S.R., Paternoster S.F., Smoley S.A., et al. Fluorescent-labeled DNA probes applied to novel biological aspects of B-cell chronic lymphocytic leukemia. Leuk Res 29 (2005) 253-262
16. Kay N.E., Bone N.D., Tschumper R.C., et al. B-CLL cells are capable of synthesis and secretion of both pro- and anti-angiogenic molecules. Leukemia 16 (2002) 911-919
17. Kay N.E., Bone N.D., Lee Y.K., et al. A recombinant IL-4 Pseudomonas exotoxin inhibits protein synthesis and overcomes apoptosis resistance in human CLL B cells. Leuk Res 29 (2005) 1009-1018
18. Mainou-Fowler T., Miller S., Proctor S.J., et al. The levels of TNFα, IL4 and IL10 production by T-cells in B-cell chronic lymphocytic leukemia (B-CLL). Leuk Res 25 (2001) 157-163
19. Grdisa M. Influence of CD40 ligation on survival and apoptosis of B-CLL cells in vitro. Leuk Res 27 (2003) 951-956
20. Levesque M.C., Chen Y., Beasley B.E., et al. Chronic lymphocytic leukemia cell CD38 expression and inducible nitric oxide synthase expression are associated with serum IL-4 levels. Leuk Res 30 (2006) 24-28
21. Frankfurt O.S., Byrnes J.J., and Villa L. Protection from apoptotic cell death by interleukin-4 is increased in previously treated chronic lymphocytic leukemia patients. Leuk Res 21 (1997) 9-16
22. Busckle M., Campana D., Carding S.R., et al. Interferon gamma inhibits apoptotic cell death in B cell chronic lymphocytic leukemia. J Exp Med 177 (1993) 213-218
23. Wierda W.G., Cantwell M.J., Woods S.J., et al. CD40-ligand (CD154) gene therapy for chronic lymphocytic leukemia. Blood 96 (2000) 2917-2924
24. Rossmann E.D., Lewin N., Jeddi-Tehrani M., et al. Intracellular T cell cytokines in patients with B cell chronic lymphocytic leukemia. Eur J Haematol 68 (2002) 299-306
25. Kamper E.F., Paraphilis A.D., Angelopoulos M.K., et al. Serum levels of tetranectin, intracellular adhesion molecule-1 and interleukin-10 in B-chronic lymphocytic leukemia. Clin Biochem 32 (1999) 639-645
26. Bialecka M., Klodowska-Duda G., Kurzawski M., et al. Interleukin-10 gene polymorphism in Parkinson's disease patients. Arch Med Res 38 (2007) 858-863
27. Bessler H., Bergman M., and Salman H. Factor(s) released from irradiated B-CLL cells induce apoptosis in leukemic lymphocytes. Cancer Lett 179 (2002) 103-108
28. Fayad L., Keating M.J., Reuben J.M., et al. Interleukin-6 and interleukin-10 levels in chronic lymphocytic leukemia: correlation with phenotypic characteristics and outcome. Blood 97 (2001) 256-263
29. Casteyon R., Vargas J., Romero Y., et al. Modulation of apoptosis by cytokines in B-cell chronic lymphocytic leukemia. Cytometry 38 (1999) 224-230
30. Chong S.Y., Lin Y.C., Czarneski J., et al. Cell cycle effects of IL-10 on malignant B-1 cells. Genes Immun 2 (2001) 239-247
31. McCarthy B.A., Mansour A., Lin Y.C., et al. RNA interference of IL-10 in leukemic B-1 cells. Cancer Immun 4 (2004) 6
32. Rosati E., Sabatini R., Tabilio A., et al. B-chronic lymphocytic leukemia cells exert an in vitro cytotoxixity mediated by tumor necrosis factor α. Leuk Res 29 (2005) 829-839
33. Bogunia-Kubik K., Mazur G., Urbanovicz I., et al. Lack of association between the TNF-α promoter gene polymorphism and susceptibility to B-chronic lymphocytic leukemia. Int J Immunogenet 33 (2006) 21-24
34. Bojarska-Junak A., Rolinski J., Wasik-Szczepanko E., et al. Intracellular tumor necrosis factor production by T and B cells in B-chronic lymphocytic leukemia. Haematologica 87 (2002) 490-499
35. Ferrajoli A., Keating M.J., Manshouri T., et al. The clinical significance of tumor necrosis factor-alpha plasma level in patients having chronic lymphocytic leukemia. Blood 100 (2002) 1215-1219
36. Kitada S., Zapata J.M., Andreeff M., et al. Bryostatin and CD40-ligand enhance apoptosis resistance and induce expression of cell survival genes in B-chronic lymphocytic leukemia. Br J Haematol 106 (1999) 995-1004
37. Munzert G., Kirchner D., Stobbe H., et al. Tumor necrosis factor receptor-associated overexpression in B-cell chronic lymphocytic leukemia: analysis of NF-kB/Rel-regulated inhibitors of apoptosis. Blood 100 (2002) 3749-3756
38. Chow K.U., Sommerland W.D., Boehrer S., et al. Anti-CD20 antibody (IDEC-C2B8, rituximab) enhances efficacy of cytotoxic drugs on neoplastic lymphocytes in vitro: role of cytokines, complement and caspases. Haematologica 87 (2002) 33-43