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Preliminary results of a phase 1/2, multi-center, open-label study (CLL-001) investigating a stepwise dose-escalation schedule of lenalidomide in relapsed or refractory chronic lymphocytic leukemia
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Treatment with lenalidomide has a positive immunomodulatory effect in patients with chronic lymphocytic leukemia
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Gao H, Ferrajoli A, Cohen EN, et al. Treatment with lenalidomide has a positive immunomodulatory effect in patients with chronic lymphocytic leukemia. Blood 2008; 112(Suppl. 1): 733 (Abstract 2107).
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A phase I study of lenalidomide in combination with fludarabine-rituximab in previously untreated CLL/SLL
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Lenalidomide-induced upregulation of CD80 on tumor cells correlates with T-cell activation, the rapid onset of a cytokine release syndrome and leukemic cell clearance in chronic lymphocytic leukemia
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