State of art on bioimaging by nanoparticles in hyperthermia and thermometry: Visualization of tissue protein targeting

Open Nanomedicine Journal

Volumn 3, Issue SPEC. ISSUE, 2011, Pages 10-23

  Sharma, R ^a,b,c   Sharma, A ^d   Chen, C J ^a  

^a FLORIDA STATE UNIVERSITY   (United States)

^b Innovations And Solutions Inc   (United States)

^c Tallahassee Community College   (United States)

^d Maharana Pratap AandT University   (India)

Author keywords

Hyperthermia; Hypoxia; Nanoparticles; Oncology; Thermal therapy; Tumor

Indexed keywords

BODY PROTEIN; CALCIUM; COBALT; COPPER 64; COPPER COMPLEX; FERRITE; GADOLINIUM; GOLD NANOPARTICLE; IRON; LANTHANUM; MACROGOL; MANGANESE; NANOPARTICLE; NITROIMIDAZOLE; PENTETIC ACID; POLYLACTIC ACID; POLYMER; POLYVINYL ALCOHOL; PROTEIN; RADIOSENSITIZING AGENT; UNCLASSIFIED DRUG; ZINC;

ARTICLE; BIOIMAGING; CANCER THERAPY; CELL SURVIVAL; CYTOTOXICITY; ENERGY; HEAT TRANSFER; HEATING; HIGH TEMPERATURE; HUMAN; HYPERTHERMIC THERAPY; IMAGING; IN VIVO STUDY; MAGNETIC RESONANCE THERMOMETRY; MAGNETISM; MONITORING; NANOMEDICINE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; THERMAL EXPOSURE; THERMOMETRY; TUMOR CELL; TUMOR LOCALIZATION; TUMOR RESISTANCE;

EID: 80051925758     PISSN: None     EISSN: 18759335     Source Type: Journal    
DOI: 10.2174/1875933501103010010     Document Type: Article

References (176)

1. Harrison GG, Saunders SJ, Biebuyck JF, et al. Anaesthetic-induced malignant hyperpyrexia and a method for its prediction. Br J Anaesth 1969; 41: 844-55.
2. Cherukuri P, Curley SA. Use of nanoparticles for targeted, noninvasive thermal destruction of malignant cells. Methods Mol Biol 2010; 624: 359-73.
3. Bellizzi G, Bucci OM. On the optimal choice of the exposure conditions and the nanoparticle features in magnetic nanoparticle hyperthermia. Int J Hyperthermia 2010; 26(4): 389-403.
4. Li Z, Kawashita M, Araki N, Mitsumori M, Hiraoka M, Doi M. Preparation of magnetic iron oxide nanoparticles for hyperthermia of cancer in a FeCl2-NaNO3-NaOH aqueous system. J Biomater Appl 2010; [Epub ahead of print].
5. Cantillon-Murphy P, Wald LL, Adalsteinsson E, Zahn M. Heating in the MRI environment due to superparamagnetic fluid suspensions in a rotating magnetic field. J Magn Magn Mater 2010; 322(6):727-33.
6. Ankamwar B, Lai TC, Huang JH, et al. Biocompatibility of Fe(3)O(4) nanoparticles evaluated by in vitro cytotoxicity assays using normal, glia and breast cancer cells. Nanotechnology 2010; 21(7): 75-102.
7. Alexiou C, Tietze R, Schreiber E, Lyer S. Nanomedicine: Magnetic nanoparticles for drug delivery and hyperthermia - new chances for cancer therapy. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2010; 53(8):839-45.
8. Chen Y, Chen BA. Application and development of magnetic ironoxide nanoparticles in tumor-targeted therapy. Ai Zheng 2010; 29(1): 118-22.
9. Sharma R, Chen CJ. Newer nanoparticles in hyperthermia treatment and thermometry. J Nanopart Res 2009; 11(3): 671-89.
10. Wust P, Hildebrandt B, Sreenivasa G, et al. Hyperthermia in combined treatment of cancer. Lancet Oncol 2002; 3: 487-97.
11. Minamimura T, Sato H, Kasaoka S, et al. Tumour regression by inductive hyperthermia combined with hepatic embolization using dextran magnetite incorporated microspheres in rats. Int J Oncol 2000; 16: 1153-8.
12. Terentyuk GS, Maslyakova GN, Suleymanova LV, et al. Laserinduced tissue hyperthermia mediated by gold nanoparticles: toward cancer phototherapy. J Biomed Opt 2009; 14(2): 021016.
13. von Maltzahn G, Park JH, Agrawal A, et al. Computationally guided photothermal tumor therapy using long-circulating gold nanorod antennas. Cancer Res 2009; 69(9): 3892-900.
14. Han B, Hanson WL, Bensalah K, Tuncel A, Stern JM, Cadeddu JA. Development of quantum dot-mediated fluorescence thermometry for thermal therapies. Ann Biomed Eng 2009; 37(6): 1230-9.
15. Wilhelm C, Fortin JP, Gazeau F. Tumour cell toxicity of intracellular hyperthermia mediated by magnetic nanoparticles. J Nanosci Nanotechnol 2007; 7(8): 2933-7.
16. Sharma HS, Sharma A, Hussain S, Schlager J, Sjöquist PO, Muresanu D. A new antioxidant compound H-290/51 attenuates nanoparticle induced neurotoxicity and enhances neurorepair in hyperthermia. Acta Neurochir Suppl 2010; 106: 351-7.
17. Cherukuri P, Glazer ES, Curley SA. Targeted hyperthermia using metal nanoparticles. Adv Drug Deliv Rev 2010; 62(3): 339-45.
18. Wen D. Intracellular hyperthermia: Nanobubbles and their biomedical applications. Int J Hyperthermia 2009; 25(7): 533-41.
19. Jordan A, Maier-Hauff K. Magnetic nanoparticles for intracranial thermotherapy. J Nanosci Nanotechnol. 2007; 7(12): 4604-6.
20. Pradhan P, Giri J, Rieken F, et al. Targeted temperature sensitive magnetic liposomes for thermo-chemotherapy. J Control Release 2010; 142(1): 108-21.
21. Le Renard PE, Jordan O, Faes A, et al. The in vivo performance of magnetic particle-loaded injectable, in situ gelling, carriers for the delivery of local hyperthermia. Biomaterials 2010; 31(4): 691-705.
22. Meenach SA, Hilt JZ, Anderson KW. Poly(ethylene glycol)-based magnetic hydrogel nanocomposites for hyperthermia cancer therapy. Acta Biomater 2010; 6(3): 1039-46.
23. Purushotham S, Ramanujan RV. Thermoresponsive magnetic composite nanomaterials for multimodal cancer therapy. Acta Biomater 2010; 6(2): 502-10.
24. Purushotham S, Chang PE, Rumpel H, et al. Thermoresponsive core-shell magnetic nanoparticles for combined modalities of cancer therapy. Nanotechnology 2009; 20(30): 305101.
25. Kaman O, Pollert E, Veverka P, et al. Silica encapsulated manganese perovskite nanoparticles for magnetically induced hyperthermia without the risk of overheating. Nanotechnology 2009; 20(27): 2756-10.
26. Prasad NK, Rathinasamy K, Panda D, Bahadur D. TC-tuned biocompatible suspension of La0.73Sr0.27MnO3 for magnetic hyperthermia. J Biomed Mater Res B Appl Biomater 2008; 85(2): 409-16.
27. Thiesen B, Jordan A. Clinical applications of magnetic nanoparticles for hyperthermia. Int J Hyperthermia 2008; 24(6): 467-74.
28. Latorre M, Rinaldi C. Applications of magnetic nanoparticles in medicine: magnetic fluid hyperthermia. P R Health Sci J 2009; 28(3): 227-38.
29. Curley SA, Cherukuri P, Briggs K, et al. Noninvasive radiofrequency field-induced hyperthermic cytotoxicity in human cancer cells using cetuximab-targeted gold nanoparticles. J Exp Ther Oncol 2008; 7(4): 313-26.
30. Cheong SK, Krishnan S, Cho SH. Modeling of plasmonic heating from individual gold nanoshells for near-infrared laser-induced thermal therapy. Med Phys 2009; 36(10): 4664-71.
31. Martinez-Boubeta C, Balcells L, Cristòfol R, et al. Self-assembled multifunctional Fe/MgO nanospheres for magnetic resonance imaging and hyperthermia. Nanomedicine 2010; 6(2): 362-370.
32. Nam J, Won N, Jin H, Chung H, Kim S. pH-Induced aggregation of gold nanoparticles for photothermal cancer therapy. J Am Chem Soc 2009; 131(38): 13639-45.
33. Salvador-Morales C, Gao W, Ghatalia P, et al. Multifunctional nanoparticles for prostate cancer therapy. Expert Rev Anticancer Ther 2009; 9(2): 211-21.
34. Tseng HY, Lee GB, Lee CY, Shih YH, Lin XZ. Localised heating of tumours utilising injectable magnetic nanoparticles for hyperthermia cancer therapy. IET Nanobiotechnol 2009; 3(2): 46-54.
35. Hadjipanayis CG, Bonder MJ, Balakrishnan S, Wang X, Mao H, Hadjipanayis GC. Metellic iron nanoparticles for MRI contract enhancement and local hyperthermia. Small 2008; 4(11): 1925-9.
36. Lal S, Clare SE, Halas NJ. Nanoshell-enabled photothermal cancer therapy: impending clinical impact. Acc Chem Res 2008; 41(12): 1842-51.
37. Jin H, Kang KA. Application of novel metal nanoparticles as optical/ thermal agents in optical mammography and hyperthermic treatment for breast cancer. Adv Exp Med Biol 2007; 599: 45-52.
38. Skrabalak SE, Au L, Lu X, Li X, Xia Y. Gold nanocages for cancer detection and treatment. Nanomedicine (Lond) 2007; 2(5): 657-68.
39. Van der Zee J. Heating the patient: a promising approach? Ann Oncol 2002; 13: 1173
40. Wang ZY, Song J, Zhang DS. Nanosized As2O3/Fe2O3 complexes combined with magnetic fluid hyperthermia selectively target liver cancer cells. World J Gastroenterol 2009; 15(24): 2995-3002.
41. Ciofani G, Riggio C, Raffa V, Menciassi A, Cuschieri A. A bimodal approach against cancer: magnetic alginate nanoparticles for combined chemotherapy and hyperthermia. Med Hypotheses 2009; 73(1): 80-2.
42. Melnikov OV, Gorbenko OY, Markelova MN, et al. Ag-doped manganite nanoparticles: new materials for temperature-controlled medical hyperthermia. J Biomed Mater Res A 2009; 91(4): 1048-55.
43. Liu C, Mi CC, Li BQ. Energy absorption of gold nanoshells in hyperthermia therapy. IEEE Trans Nanobiosci 2008; 7(3): 206-14.
44. Huang X, Qian W, El-Sayed IH, El-Sayed MA. The potential use of the enhanced nonlinear properties of gold nanospheres in photothermal cancer therapy. Lasers Surg Med 2007; 39(9): 747-53.
45. Han S, Lin J, Zhou F, Vellanoweth RL. Oligonucleotide-capped gold nanoparticles for improved atomic force microscopic imaging and enhanced selectivity in polynucleotide detection. Biochem Biophys Res Commun 2000; 279(1): 265-9.
46. Heinfeld JF, Slatkin DN, Focella TM, Smilowitz HM. Gold nanoparticles: a new X-ray contrast agent. Br J Radiol 2006; 79: 248-53.
47. Naruse S, Higuchi T, Horikawa Y, Tanaka C. Radiofrequency hyperthermia with successive monitoring of its effects on tumors using NMR spectroscopy. Proc Natl Acad Sci USA 1986; 83(21): 8343-7.
48. Zhu D, Lu W, Weng Y, Cui H, Luo Q. Monitoring thermal-induced changes in tumor blood flow and microvessels with laser speckle contrast imaging. Appl Opt 2007; 46(10):1911-7.
49. Ito A, Tanaka K, Kondo K, et al. Tumor regression by combined immunotherapy and hyperthermia using magnetic nanoparticles in an experimental infcutaneous murine melanoma. Cancer Sci 2003; 94 (3): 308-13.
50. Ghosh S, Dutta S, Gomes E, et al. Increased heating efficiency and selective thermal ablation of malignant tissue with DNA-encased multiwalled carbon nanotubes. ACS Nano 2009; 3(9): 2667-73.
51. Sharma R. Nanoparticles that facilitate imaging of biological tissue and methods of forming the same. US Patent 200900220434 Sept 3.
52. Oh P, Borgström P, Witkiewicz H, et al. Live dynamic imaging of caveolae pumping targeted antibody rapidly and specifically across endothelium in the lung. Nat Biotechnol 2007; 25(3): 327-37.
53. Gellermann J, Wlodarczyk W, Feussner A, et al. Methods and potentials of magnetic resonance imaging for monitoring radiofrequency hyperthermia in a hybrid system. Int J Hyperthermia 2005; 21: 497-513.
54. Salloum M, Ma R, Zhu L. Enhancement in treatment planning for magnetic nanoparticle hyperthermia: optimization of the heat absorption pattern. Int J Hyperthermia 2009; 25(4): 309-21.
55. Maswadi SM, Dodd SJ, Gao JH, Glickman RD. Temperature mapping of laser-induced hyperthermia in an ocular phantom using magnetic resonance thermography. J Biomed Opt 2004; 9(4):711-8.
56. Heisterkamp J, vanHillegersberg R, Ijzermans JNM. Critical temperature and heating time for coagulation damage: Implications for interstitial laser coagulation (ILC) of tumors. Lasers Surg Med 1999; 25: 257-62.
57. Lewin JS, Conell CF, Duerk JL, et al. Interactive MRI-guided radiofrequency interstitial thermal ablation of abdominal tumors: Clinical trial for evaluation of safety and feasibility. J Magn Reson Imaging 1998; 8: 40-47.
58. Hiroka M, Mitsumori M, Hiroi N, et al. Development of RF and microwave heating equipment and clinical application to cancer treatment in japan. IEEE Trans Microw Theory Tech 2000; 48: 1789-99.
59. McFerrin MB, Sontheimer H. Optical and MRI multifunctional nanoprobe for targeting gliomas. Neuron Glia Biol 2006; 2(1):39-49.
60. Baker I, Zeng Q, Li W, Sullivan CR. Heat deposition in iron oxide and iron nanoparticles for localized hyperthermia. J Appl Phys 2006; 99(8): 106.
61. Pankhurst QA, Connolly J, Jones SK, Dobson J. Applications of magnetic nanoparticles in biomedicine. J Phys D: Appl Phys 2003; 36:167-81.
62. Moroz P, Jones SK, Gray BN. Magnetically mediated hyperthermia: Current status and future directions. Int J Hyperthermia 2002; 18: 267-84.
63. Jordan A, Scholz R, Maier-Hauff K, et al. Presentation of a new magnetic field therapy system for the treatment of human solid tumors with magnetic fluid hyperthermia. J Magn Magn Mater 2001; 225(1): 118-26.
64. Kong G, Braun RD, Dewhirst MW. Characterization of the effect of hyperthermia on nanoparticle extravasation from tumor vasculature. Cancer Res 2001; 61: 3027.
65. Fortin JP, Gazeau F, Wilhelm C. Intracellular heating of living cells through Néel relaxation of magnetic nanoparticles. Eur Biophys J 2008; 37(2): 223-8.
66. Atsarkin VA, Levkin LV, Posvyanskiy VS, et al. Solution to the bioheat equation for hyperthermia with La(1-x)Ag(y)MnO(3-delta) nanoparticles: the effect of temperature autostabilization. Int J Hyperthermia 2009; 25(3): 240-7.
67. Hergt R, Dutz S, Zeisberger M. Validity limits of the Néel relaxation model of magnetic nanoparticles for hyperthermia. Nanotechnology 2010; 21(1): 015706.
68. Tanaka K, Ito K, Kobayashi T, et al. Intratumoral injection of immature dendrite cells enhances antitumor effect of hyperthermia using magnetic nanoparticles. Int J Cancer 2005; 116: 624-33.
69. Nedelcu G. Magnetic nanoparticles impact on tumoral cells in the treatment by magnetic fluid hyperthermia. Digest J Nanomater Biostruct 2008; 3(3): 103-17.
70. Khanafer KK, Vafai KA, Kangarlu A. Water diffusion in biomedical systems as related to magnetic resonance imaging. Magn Reson Imaging 2003; 21: 17-31.
71. Sonvico F, Mornet S, Vasseur S, et al. Folate-conjugated ironoxide nanoparticles for solid tumor targeting as potential specific magnetic hyperthermia mediators: Synthesis, physiochemical characterization, and in vitro experiments. Bioconjug Chem 2005; 16: 1181-8.
72. Kim S, Loevner LA, Quon H, et al. Prediction of response to chemoradiation therapy in squamous cell carcinomas of the head and neck using dynamic contrast-enhanced mr imaging. AJNR Am J Neuroradiol 2010; 31: 262-8.
73. Moroz P, Jones SK, Gray BN. Tumor response to aterial embolization hyperthermia and direct injection hyperthermia in a rabbit liver tumor model. J Surg Oncol 2002; 80: 149-56.
74. Kraus RH, Wright B. In: Biomedical applications of nanotechnology. In: Labhasetwar V, Leslie-Pelecky DL, Eds. agnetic nanoparticles in cancer diagnosis and hyperthermic treatment. John Wiley and Sons, Inc. 2007; pp. 65-82.
75. Silver FH. Mechanochemical transduction and its role in biology. In: Mechanosensing and mechanochemical transduction in extracellular matrix biological, chemical, engineering, and physiological aspects. US Springer Verlag 2002: pp. 262-70.
76. Hayek SS, Sharma R, Kwon S, Sharma A, Chen CJ. Temperature and magnetic resonance characteristics of zinc, manganese, gadolinium, gold, iron magnetic nanoparticles and cytokine synergy in hyperthermia. J Biomed Sci Eng 2008; 1(3):147-209.
77. Brusentsov N, Nikitin L, Brusentsova T, et al. Magnetic fluid hyperthermia of the mouse experimental tumor. J Magn Magn Matr 2002; 252: 378-80.
78. Cho YW, Park SA, Han TH, et al. In vivo tumor targeting and radionuclide imaging with self-assembled nanoparticles: mechanisms, key factors, and their implications. Biomaterials 2007; 28(6):1236-47.
79. Nigavekar SS, Sung LY, Llanes M, et al. 3H Dendrimer Nanoparticle Organ/Tumor Distribution. Pharm Res 2004; 21(3):476-83.
80. Jonsson PE, Garcia-Palacios JL, Hansen MF, Norblad P. Relaxation in interacting nanoparticel systems. J Mol Liq 2004; 114: 131-5.
81. MacFall JR, Prescott DM, Charles HC. MRI phase thermometry in vivo in canine brain, muscle, and tumor tissue. Med Phys 1996; 23(10): 1775-82.
82. Haemmerich D, Santos I, Schutt DJ, Webster JG, Mahvid DM. In vitro measurements of temperature-dependent specific heat of liver tissue. Med Eng Phys 2006; 28: 194-7.
83. Maswadi SM, Dodd SJ, Gao JH, Glickman RD. Temperature mapping of laser-induced hyperthermia in an ocular phantom using magnetic resonance thermography. J Biomed Opt 2004; 9(4): 711-8.
84. Amao Y, Okura I. Fullerene C60 immobilized in polymethylmethacrylate film as an optical temperature sensing material. Analysis 2000; 28: 847-9.
85. Smith CR, Sabatino DR, Praisner TJ. Temperature sensing with thermochromic liquid crystals. Exp Fluids 2001; 30: 190-201.
86. Maqueda RJ, Wurden GA, Terry JL, Stillerman JA. The new infrared imaging sysem on Alcator C-Mod. Rev Sci Instrum 2000; 70: 734-7.
87. Settecase F, Sussman MS, Roberts TPL. A new temperaturesensitive contrast mechanism for mri: curie temperature transitionbased imaging. Contrast Media Mol Imaging 2007; 2: 50-54.
88. Auzans E, Zins D, Blums E, Massart R. Synthesis and properties of Mn-Zn ferrite ferrofluids. J Mater Sci 1999; 34: 1253-60.
89. Warheit DB, Sayes CM, Reed KL. Nanoscale and fine zinc oxide particles: can in vitro assays accurately forecast lung hazards following inhalation exposures? Environ Sci Technol 2009; 43(20): 7939-45.
90. Babincov M, Altanerov V, Altaner C, Bergemann C, Babinec P. In vitro analysis of cisplatin functionalized magnetic nanoparticles incombined cancer chemotherapy and electromagnetic hyperthermia. IEEE Trans Nanobiosci 2008; 7(1): 15-9.
91. Villa A, Gill H, McCallion O, Alonso M. Transport of PLA-PEG particles across the nasal mucosa: effect of particle size and PEG coating density. J Control Release 2004; 98: 231-44.
92. Krause W, Hackmann-Schlichter N, Franz Karl Maier FK, Müller R. Dendrimers in diagnostics. In: Topics in current chemistry. dendrimers ii architecture, nanostructure and supramolecular chemistry. Berlin: US Springer Link 2000; 210: 261-308.
93. Brusentsova TN, Brusentsov NA, Kuznetsov VD, Nikiforov VN. Synthesis and investigation of magnetic properties of Gdinfstituted Mn-Zn ferrite nanoparticles as a potential low-TC agent for magnetic fluid hyperthermia. J Magn Magn Mater 2005; 293(1): 298-302.
94. Jennifer A, Nelson, Lawrence H. Bennett, Michael J. Wagner Solution, synthesis of gadolinium nanoparticles. J Am Chem Soc 2002; 124(12): 2979-83.
95. Turner JL, Pan D, Plummer R, Chen Z, Whittaker AK, Wooley KL. Synthesis of gadolinium-labeled shell-crosslinked nanoparticles for magnetic resonance imaging applications. Adv Funct Mater 2005; 15(8): 1248-54.
96. Wlodarczyk W, Boroschewski R, Hentschel M, Wust P, Mönich G, Felix R. Three-dimensional monitoring of small temperature changes for therapeutic hyperthermia using MR. J Magn Reson Imaging 2005; 8(1):165-74.
97. de Senneville BD, Mougenot C, Quesson B, Dragonu I, Grenier N, Moonen CT. MR thermometry for monitoring tumor ablation. Eur Radiol 2007; 17(9): 2401-10.
98. Arthur RM, Straube WT, Trobaugh JW, Moros EG. Non-invasive estimation of hyperthermia temperatures with ultrasound. Int J Hyperthermia 2005; 21(6): 589-600.
99. Catherina SP, van Rijswijk, Geirnaerdt MJA, et al. Dynamic contrast- enhanced MR imaging in monitoring response to isolated limb perfusion in high-grade soft tissue sarcoma: initial results. Eur Radiol 2003; 13(8): 1849-58.
100. Fortin JP, Wilhelm C, Gazeau F, et al. Use of magnetic nanoparticles as intracellular agents for hyperthermia. Contrast Media Mol Imaging 2006; 1(2): 56-7.
101. Kussman BD, Mulkern RV, Holzman RS. Iatrogenic hyperthermia during cardiac magnetic resonance imaging. Anesth Analg 2004; 99:1053-5.
102. Reinl HM, Peller M, Hagmann M, Turner P, Issels R, Reiser M. Ferrite-enhanced MRI monitoring in hyperthermia. Magn Reson Imaging 2005; 23(10): 1017-20.
103. M. Hyperthermia induces T1 relaxation and blood flow changes in tumors. A MRI thermometry study in vivo. Magn Reson Imaging 2003; 21(5): 545-51.
104. Karam JA, Mason RP, Koeneman KS, Antich PP, Benaim EA, Hsieh TJ. Molecular Imaging in Prostate Cancer. J Cell Biochem 2003; 90: 473-83.
105. Cheng KH, Hernandez M. Magnetic resonance diffusion imaging detects structural damage in biological tissues upon hyperthermia. Cancer Res 1992; 52(11): 6066-73.
106. Ponce AM, Viglianti BL, Yu D, et al. Magnetic resonance imaging of temperature-sensitive liposome release: drug dose painting and antitumor effects. J Natl Cancer Inst 2007; 99(1): 53-63.
107. Hey S, Maclair GB, de Senneville D, et al. Online correction of respiratory-induced field disturbances for continuous MRthermometry in the breast. Magn Reson Med 2009; 61(6): 1494-9.
108. Kircher MF, Mahmood U, King RS, Weissleder R, Josephson L. A multimodal nanoparticle for preoperative magnetic resonance imaging and intraoperative optical brain tumor delineation. Cancer Res 2003; 63: 8122-5.
109. Sosnovik DE, Schellenberger EA, Nahrendorf M, et al. Magnetic resonance imaging of cardiomyocyte apoptosis with a novel magneto-optical nanoparticle. Magn Reson Med 2005; 54: 718-24.
110. Veiseh O, Sun C, Gunn J, et al. Optical and MRI multifunctional nanoprobe for targeting gliomas. Nano Lett 2005; 5: 1003-8.
111. Yu SB, Watson AD. Metal-based X-ray contrast media. Chem Rev 1999; 99(9): 2353-78.
112. Ritman EL. Molecular imaging in small animals-roles for micro- CT. J Cell Biochem 2002; 87(39): 116-24.
113. Chivukula VS, Shur MS, Ciplys D. Recent advances in application of acoustic, acousto-optic and photoacoustic methods in biology and medicine. Phys Status Solidi(A) 2007; 204(10): 3209-36.
114. Li FR, Yan WH, Guo YH, Qi H, Zhou HX. Preparation of carboplatin- Fe@C-loaded chitosan nanoparticles and study on hyperthermia combined with pharmacotherapy for liver cancer. Int J Hyperthermia 2009; 25(5): 383-91.
115. Martina MS, Fortin JP, Menager C, et al. Generation of superparamagnetic liposomes revealed as highly efficient MRI contrast agents for in vivo imaging. J Am Chem Soc 2005; 127: 10676-85.
116. Romanus E, Huckel M, Gross C, et al. Magnetic nanoparticles relaxation measurement as a novel tool for in vivo diagnostics. J Magn Magn Mater 2002; 252: 387-9.
117. McDermott R, Kelso N, Lee SK, et al. SQUID-detected magnetic resonance imaging in microtesla magnetic fields. J Low Temp Phys 2004; 135: 793-821.
118. Allen M, Bulte JWM, Liepold L, et al. paramagnetic viral nanoparticles as potential high-relaxivity magnetic resonance contrast magnets. Magn Reson Med 2005; 54: 807-12.
119. Plassat V, Martina MS, Barratt G, Ménager C, Lesieur S. Sterically stabilized superparamagnetic liposomes for MR imaging and cancer therapy: pharmacokinetics and biodistribution. Int J Pharm 2007; 344(1-2): 118-27.
120. Alexiou, C, Arnold W, Hulin P, Klein RJ, Renz H, Parak FG, et al. Magnetic mitoxantrone nanoparticle detection by histology, X-ray and MRI after magnetic tumor targeting. J Magn Magn Mater 2001; 225: 187-193.
121. Zhao, M, Beauregard DA, Loizou L, Davletov B, Brindle KM. Non-invasive dtection of apoptosis using magnetic resonance imaging and a targeted contrast agent. Nat Med 2001; 7: 1241-3.
122. Bodurka J, Bandettini PA. Toward direct mapping of neuronal activity: MRI detection of ultraweak, transient magnetic field changes. Magn Reson Med 2002; 47: 1052-8.
123. Konn, D, Gowland P, Bowtell R. MRI detection of weak magnetic fields due to an extended current dipole in a conducting sphere: A model for direct detection of neuronal currents in the brain. Magn Reson Med 2003; 50(1): 40-49.
124. McDermott R, Trabesinger AH, Muck M, Hahn EL, Pines A, Clarke J. Liquid-state NMR and scalar coupling in microtesla magnetic fields. Science 2002; 295: 2247-9.
125. Volegov P, Matlachov AN, Espy MA, George JS, Kraus RH Jr. Simultaneous magnetoencephalography and SQUID detected nuclear MR in microtesla magnetic fields. Magn Reson Med 2004; (52)3: 467-70.
126. Romanus E, Berkov DV, Prass S, Grob C, Weitschies W, Weber P. Determination of energy barrier distributions of magnetic nanoparticles by temperature dependent magnetorelaxometry. Nanotechnology 2003; 14: 1251-4.
127. Sharma R. Kwon S. New applications of nanoparticles in cardiovascular imaging. J Exp Nanosci 2007; 2(1): 115-23.
128. Matlachov AN, Volegov PL, Espy MA, Kraus RH. SQUID detected NMR in microtesla magnetic fields. J Magn Reson 2004; 170: 1-7.
129. Huff TB, Tong L, Zhao Y, Hansen MH, Cheng JX, Wei A. Hyperthermic effects of gold nanorods on tumor cells. Nanomedicine 2007; 2(1): 125-32.
130. Visaria RK, Griffin RJ, Williams BW, et al. Enhancement of tumor thermal therapy using gold nanoparticle-assisted tumor necrosis factor-7alpha; delivery. Mol Cancer Ther 2006; 5:1014-20.
131. Wijaya A, Brown KA, Alper JD, Hamad-Schifferli K. Magnetic field heating study of Fe-doped Au nanoparticles. J Magn Magn Mater 2007; 309(1): 15-9.
132. Huang WC, Chen YC. Photochemical synthesis of polygonal gold nanoparticles. J Nanopart Res 2008; 10(4): 697-702.
133. Katti KV, Kannan R, Katti K, et al. Hybrid gold nanoparticles in molecular imaging and radiotherapy Czech J Phys 2006; 56(1):23-34.
134. Alric C, Taleb J, Le Duc G, et al. Gadolinium chelate coated gold nanoparticles as contrast agents for both X-ray computed tomography and magnetic resonance imaging. J Am Chem Soc 2008; 130(18): 5908-15.
135. Mallidi S, Larson T, Aaron J, Sokolov K, Emelianov S. molecular specific optoacoustic imaging with plasmonic nanoparticles. Opt Express 2007; 15(11): 6583-8.
136. 4. J Magn Magn Mater 2007; 311(1): 22-5.
137. Sutariya GM, Vincent D, Bayard B, Upadhyay RV, Noyel G, Mehta RV. Magnetic DC field and temperature dependence on complex microwave magnetic permeability of ferrofluids: effect of constituent elements of infstituted Mn ferrite. J Magn Magn Mater 2003; 260(1-2): 42-7.
138. Sharma R. Gadolinium Toxicity: epidermis thickness measurement by magnetic resonance imaging at 500 MHz. Skin Res Technol 2010; 28(5): 339-53.
139. Caravan P. Protein-targeted gadolinium-based magnetic resonance imaging (MRI) contrast agents: design and mechanism of action. Acc Chem Res 2009; 42(7): 851-62.
140. Drake P, Cho HJ, Shih PS, et al. Gd-doped iron-oxide nanoparticles for tumour therapy via magnetic field hyperthermia. J Mater Chem 2007; 17: 4914.
141. Uskoković W, Koak A, Drofenik M, Drofenik M. Preparation of Silica-Coated Lanthanum-Strontium manganite particles with designable Curie Point, for application in hyperthermia treatments. Int J Appl Ceram Tech 2006; 3(2): 134-43.
142. 3+ doping on MnZn ferrite nanoscale particles synthesized by hydrothermal method. J Central South Univ Technol 2004; 11(2): 113-228.
143. Shuai J, Parker I. Optical single-channel recording by imaging Ca2+ flux through individual ion channels: theoretical considerations and limits to resolution. Cell Calcium 2005; 37(4): 283-99.
144. Demuro A, Parker I. Imaging single-channel calcium microdomains. Cell Calcium 2006; 40(5-6): 413-22.
145. Hou CH, Chen CW, Hou SM, Li YT, Lin FH. The fabrication and characterization of dicalcium phosphate dihydrate-modified magnetic nanoparticles and their performance in hyperthermia processes in vitro. Biomaterials 2009; 30(27): 4700-7.
146. Hou CH, Hou SM, Hsueh YS, Lin J, Wu HC, Lin FH. The in vivo performance of biomagnetic hydroxyapatite nanoparticles in cancer hyperthermia therapy. Biomaterials 2009; 30(23-24): 3956-60.
147. Buzas CJ, Pacher P, Rosenberg H, Hajnoczky G. Single cell calcium imaging cell calcium imaging studies of pathomchanism of malignant hyperthermia. Biophys J 2002; 82 (1): 649.
148. Plotkin M, Gneveckow U, Meier-Hauff K, et al. 18F-FET PET for planning of thermotherapy using magnetic nanoparticles in recurrent glioblastoma. Int J Hyperthermia 2006; 22(4): 319-25.
149. Lanza GM, Winter PM, Caruthers SD, et al. Magnetic resonance molecular imaging with nanoparticles. J Nucl Cardiolol 2004; 11:733-743.
150. Nahrendorf M, Zhang H, Hembrador S, et al. Nanoparticle PETCT imaging of macrophages in inflammatory atherosclerosis. Circulation 2008; 117(3): 379-87.
151. Palussière J, Salomir R, Bail BL, Fawaz R, Quesson B, Grenier N, Moonen CTW. Feasibility of MR-guided focused ultrasound with real-time temperature mapping and continuous sonication for ablation of VX2 carcinoma in rabbit thigh. Magn Reson Med 2002; 47 (6):1065-72.
152. Corchero JL, Villaverde A. Biomedical applications of distally controlled magnetic nanoparticles. Trends Biotechnol 2009; 27(8): 468-76.
153. Statford IJ, Adams GE. Effect of hyperthermia on differential cytotoxiciy of a hypoxic cell radiosensitizer Ro-07-0582 on mammalian cells in vitro. Radiat Res 1976; 67 (3): 459-73.
154. Emi, Maehara Y, Kusumoto T, Baba H, Sakaguchi M, Sugimachi K. Hyperthermia enhances the cytotoxicity against hypoxic cells of RP-170, a new 2-nitroimidazole nucleoside hypoxic cell sensitizer. Oncology 1995; 52: 55-9.
155. Tamuelvicius P, George KC, Rücker A, Streffer C. Effects of local hyperthermia on the tissue levels and toxicity of three radiosensitizers in mice. Int J Hyperthermia 1992; 8(3): 321-8.
156. Teicher BA, Herman TS, Holden SA, Jones SM. Addition of misonidazole, etanidazole, or hyperthermia to treatment with fluosol da/carbogen/radiation. J Natl Cancer Inst 1989; 81(12): 929-34.
157. Walton MI, Bleehen NM, Workman P. Stimulation by localized tumor hyperthermia of reductive bioactivation of 2-nitroimidazole benznidazole in mice. Cancer Res 1989; 49: 2351-5.
158. Herman TS, Teicher BA, Holden SA, Pfeffer MR, Jones SM. Addition of 2-nitroimidazole radiosensitizers to cis-diamminedichloroplatinum(II) with radiation and with or without hyperthermia in the murine FSaIIC fibrosarcoma. Cancer Res 1990; 50(9): 2734-40.
159. Fujimoto S, Ohta M, Shrestha RD, et al. Enhancement of hyperthermochemotherapy for human gastric cancer in nude mice by thermosensitization with nitroimidazoles. Br J Cancer 1988; 58(1): 42-5.
160. Mahy P, Geets X, Lonneux M, et al. Determination of tumour hypoxia with [18F]EF3 in patients with head and neck tumours: a phase I study to assess the tracer pharmacokinetics, biodistribution and metabolism. Eur J Nucl Med Mol Imaging 2008; 35(7): 1282-9.
161. Procissi D, Claus F, Burgman P, et al. In vivo 19F magnegnetic resonance spectroscopy and chemical shift imaging of tri-fluoronitroimidazole as a potential hypoxia reporter in solid tumors. Clin Cancer Res 2007; 13(12): 3738-47.
162. Jaiswal MK, Banerjee R, Pradhan P, Bahadur D. Thermal behavior of magnetically modalized poly(N-isopropylacrylamide)-chitosan based nanohydrogel. Colloids Surf B Biointerfaces 2010; 81(1): 185-94.
163. Johannsen M, Thiesen B, Wust P, Jordan A. Magnetic nanoparticle hyperthermia for prostate cancer. Int J Hyperthermia 2010; 26(8): 790-5.
164. Yang C, Jie R, Jianbo L, Yan L. Thermo-responsive Mn- ZnFerrite/Poly(N,N'-Isopropyl Acrylamide-co-N-Hydroxymethylacrylamide) core/shell nanocomposites for drug-delivery systems. J Biomater Sci Polym Ed 2010; [Epub ahead of print].
165. Sirotkina MA, Elagin VV, Shirmanova MV, et al. OCT-guided laser hyperthermia with passively tumor-targeted gold nanoparticles. J Biophotonics 2010; 3(10-11): 718-27.
166. Martín-Saavedra FM, Ruíz-Hernández E, Boré A, Arcos D, Vallet- Regí M, Vilaboa N. Magnetic mesoporous silica spheres for hyperthermia therapy. Acta Biomater 2010; 6(12): 4522-31.
167. Sanson C, Diou O, Thevenot J, et al. Doxorubicin loaded magnetic polymersomes: theranostic nanocarriers for MR imaging and magneto- chemotherapy. ACS Nano 2011; 5(2): 1122-1140.
168. Sato A, Tamura Y, Sato N, et al. Melanoma-targeted chemothermo- immuno (CTI)-therapy using N-propionyl-4-Scysteaminylphenol- magnetite nanoparticles elicits CTL response via heat shock protein-peptide complex release. Cancer Sci 2010; 101(9): 1939-46.
169. Giordano MA, Gutierrez G, Rinaldi C. Fundamental solutions to the bioheat equation and their application to magnetic fluid hyperthermia. Int J Hyperthermia 2010; 26(5): 475-84.
170. Cheng KS, Stakhursky V, Stauffer P, Dewhirst M, Das SK. Online feedback focusing algorithm for hyperthermia cancer treatment. Int J Hyperthermia 2007; 23(7): 539-54.
171. Stakhursky VL, Arabe O, Cheng KS, et al. Real-time MRI-guided hyperthermia treatment using a fast adaptive algorithm. Phys Med Biol 2009; 54(7): 2131-45.
172. Cheng KS, Dewhirst MW, Stauffer PR, Das S. Effective learning strategies for real-time image-guided adaptive control of multiplesource hyperthermia applicators. Med Phys 2010; 37(3): 1285-97.
173. Ahamed M, Akhtar MJ, Siddiqui MA, et al. Oxidative stress mediated apoptosis induced by nickel ferrite nanoparticles in cultured A549 cells. Toxicology 2011 Mar 4; [Epub ahead of print].
174. Liu L, Ni F, Zhang J, Jiang X, Lu X, Guo Z, Xu R. Silver nanocrystals sensitize magnetic-nanoparticle-mediated thermo-induced killing of cancer cells. Acta Biochim Biophys Sin (Shanghai) 2011 Mar 3; [Epub ahead of print].
175. Tagami T, Ernsting MJ, Li SD. Efficient tumor regression by a single and low dose treatment with a novel and enhanced formulation of thermosensitive liposomal doxorubicin. J Control Release 2011 Feb 19; [Epub ahead of print].
176. Wu YN, Chen DH, Shi XY, Lian CC, Wang TY, Yeh CS, Ratinac KR, Thordarson P, Braet F, Shieh DB. Cancer-cell-specific cytotoxicity of non-oxidized iron elements in iron core-gold shell NPs. Nanomedicine 2011 Jan 25; [Epub ahead of print].