Impaired reproduction in adult male, but not female, rats following juvenile treatment with the aromatase inhibitor, exemestane

Birth Defects Research Part B - Developmental and Reproductive Toxicology

Volumn 92, Issue 4, 2011, Pages 304-313

  Cappon, Gregg D ^a   Chapin, Robert E ^a   Hurtt, Mark E ^a   Wajnrajch, Michael P ^a   Burns Naas, Leigh Ann ^a  

^a PFIZER INC   (United States)

Author keywords

Aromatase inhibitor; Exemestane; Juvenile toxicity; Puberty; Rat; Reproduction

Indexed keywords

EXEMESTANE;

ANIMAL EXPERIMENT; ARTICLE; CELL COUNT; CELL PROLIFERATION; COITUS; CONTROLLED STUDY; DRUG EXPOSURE; FEMALE; FEMUR; FERTILITY; JUVENILE ANIMAL; LITTER SIZE; MALE; MATING; NONHUMAN; PREGNANCY RATE; PRIORITY JOURNAL; RAT; REPRODUCTION; SERTOLI CELL; SEXUAL MATURATION; TESTIS WEIGHT;

ABNORMALITIES, DRUG-INDUCED; ANDROSTADIENES; ANIMALS; AROMATASE INHIBITORS; BODY WEIGHT; FEMALE; FERTILITY; MALE; ORGAN SIZE; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCTION; SERTOLI CELLS; SEXUAL MATURATION;

RATTUS;

EID: 80051917562     PISSN: 15429733     EISSN: 15429741     Source Type: Journal    
DOI: 10.1002/bdrb.20307     Document Type: Article

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