Histologic and cytologic detection of endocrine and reproductive tract effects of exemestane in female rats treated for up to twenty-eight days

Toxicologic Pathology

Volumn 39, Issue 4, 2011, Pages 589-605

  Mirsky, Michael L ^a   Sivaraman, Lakshmi ^b   Houle, Christopher ^a   Potter, David M ^a   Chapin, Robert E ^a   Cappon, Gregg D ^a  

^a PFIZER INC   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

Author keywords

aromatase inhibitor; exemestane; mammary gland; ovary; rat; uterus; vagina

Indexed keywords

EXEMESTANE;

ADRENAL GLAND; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ESTRUS CYCLE; FEMALE; FOLLICLE CYST; GRANULOCYTE; GYNECOLOGIC DISEASE; HISTOPATHOLOGY; HORMONE BLOOD LEVEL; HYPOPHYSIS; HYPOPHYSIS PARS DISTALIS; MAMMARY GLAND; MENSTRUATION DISORDER; NONHUMAN; OVARY FOLLICLE; PRIORITY JOURNAL; RAT; SYMPTOMATOLOGY; UTERINE CERVIX CYTOLOGY; UTERINE CERVIX DISEASE; UTERUS WEIGHT; VAGINA SMEAR; ZONA FASCICULATA;

ADRENAL GLANDS; ANDROSTADIENES; ANIMALS; AROMATASE INHIBITORS; ATROPHY; DIESTRUS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; FEMALE; FOLLICULAR CYST; HORMONES; MAMMARY GLANDS, ANIMAL; ORGAN SIZE; OVARIAN FOLLICLE; PITUITARY GLAND; RATS; RATS, SPRAGUE-DAWLEY; UTERINE CERVICAL DISEASES; VAGINA;

RATTUS;

EID: 79959443160     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1177/0192623311402220     Document Type: Article

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