Reducing endogenous estrogens during the neonatal and juvenile periods affects reproductive tract development and sperm production in postpuberal boars

Animal Reproduction Science

Volumn 109, Issue 1-4, 2008, Pages 218-235

  Berger, Trish ^a   McCarthy, Megan ^a   Pearl, Christopher A ^a   At Taras, Eeman ^a   Roser, Janet F ^a   Conley, Alan ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Accessory sex glands; Boar sperm; Fertility; Pig male reproduction; Prostate; Testis

Indexed keywords

AROMATASE INHIBITOR; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; LETROZOLE; NITRILE; TESTOSTERONE; TRIAZOLE DERIVATIVE;

ANIMAL; ARTICLE; BLOOD; CELL DIVISION; CYTOLOGY; DRUG EFFECT; EPIDIDYMIS; GENETICS; GROWTH, DEVELOPMENT AND AGING; HISTOLOGY; MALE; MOUSE; MOUSE MUTANT; NEWBORN; ORGAN SIZE; PHYSIOLOGY; SERTOLI CELL; SEXUAL MATURATION; SPERMATOZOON; SWINE; TESTIS;

ANIMALS; ANIMALS, NEWBORN; AROMATASE INHIBITORS; CELL DIVISION; EPIDIDYMIS; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; ESTROGENS; MALE; MICE; MICE, KNOCKOUT; NITRILES; ORGAN SIZE; SERTOLI CELLS; SEXUAL MATURATION; SPERMATOZOA; SWINE; TESTIS; TESTOSTERONE; TRIAZOLES;

ANIMALIA; SUIDAE; ZEA MAYS;

EID: 54149114751     PISSN: 03784320     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.anireprosci.2007.10.003     Document Type: Article

References (42)

1. Amann R.P., and Almquist J.O. Reproductive capacity of dairy bulls I. Technique for direct measurement of gonadal and extra-gonadal sperm reserves. J. Dairy Sci. 44 (1961) 1537-1545
2. Amann R.P., and Lambiase Jr. J.T. The male rabbit III. Determination of daily sperm production by means of testicular homogenates. J. Anim. Sci. 28 (1969) 369-374
3. At-Taras E.E., Berger T., McCarthy M.J., Conley A.J., Nitta-Oda B.J., and Roser J.F. Reducing estrogen synthesis in developing boars increases testis size and total sperm production. J. Androl. 27 (2006) 552-559
4. At-Taras E.E., Conley A.J., Berger T., and Roser J.F. Reducing estrogen synthesis does not affect gonadotropin secretion in the developing boar. Biol. Reprod. 74 (2006) 58-66
5. Baines H., Nwagwu M.O., Furneaux E.C., Stewart J., Kerr J.B., Mayhew T.M., and Ebling F.J. Estrogenic induction of spermatogenesis in the hypogonadal (hpg) mouse: role of androgens. Reproduction 130 (2005) 643-654
6. Berger T., and Clegg E.D. Effect of male accessory gland secretions on sensitivity of porcine sperm acrosomes to cold shock, initiation of motility and loss of cytoplasmic droplets. J. Anim. Sci. 60 (1985) 1295-1302
7. Berger T., and Parker K. Modification of the zona-free hamster ova bioassay of boar sperm fertility and correlation with in vivo fertility. Gamete Res. 22 (1989) 385-397
8. Berger T., Turner K.O., Meizel S., and Hedrick J.L. Zona pellucida-induced acrosome reaction in boar sperm. Biol. Reprod. 40 (1989) 525-530
9. Bianco J.J., Handelsman D.J., Pedersen J.S., and Risbridger G.P. Direct response of the murine prostate gland and seminal vesicles to estradiol. Endocrinology. 143 (2002) 4922-4933
10. Bianco J.J., McPherson S.J., Wang H., Prins G.S., and Risbridger G.P. Transient neonatal estrogen exposure to estrogen-deficient mice (aromatase knockout) reduces prostate weight and induces inflammation in late life. Am. J. Pathol. 168 (2006) 1869-1878
11. Cho H.W., Nie R., Carnes K., Zhou Q., Sharief N.A., and Hess R.A. The antiestrogen ICI 182,780 induces early effects on the adult male mouse reproductive tract and long-term decreased fertility without testicular atrophy. Reprod. Biol. Endocrinol. 1 (2003) 57
12. Christenson R.K., Ford J.J., and Redmer D.A. Estradiol and testosterone metabolic clearance and production rates during puberal development in boars. Biol. Reprod. 31 (1984) 905-912
13. Claus R., and Hoffmann B. Oestrogens, compared to other steroids of testicular origin, in blood plasma of boars. Acta Endocrinol. (Copenh) 94 (1980) 404-411
14. Couse J.F., and Korach K.S. Estrogen receptor null mice: what have we learned and where will they lead us?. Endocr Rev. 20 (1999) 358-417
15. Couse J.F., Lindzey J., Grandien K., Gustafsson J.A., and Korach K.S. Tissue distribution and quantitative analysis of estrogen receptor-alpha (ERalpha) and estrogen receptor-beta (ERbeta) messenger ribonucleic acid in the wild-type and ERalpha-knockout mouse. Endocrinology 138 (1997) 4613-4621
16. Davies D.C., Hall G., Hibbitt G., and Moore H.D. The removal of the seminal vesicles from the boar and the effects on the semen characteristics. J. Reprod. Fertil. 43 (1975) 305-312
17. Eddy E.M., Washburn T.F., Bunch D.O., Goulding E.H., Gladen B.C., Lubahn D.B., and Korach K.S. Targeted disruption of the estrogen receptor gene in male mice causes alteration of spermatogenesis and infertility. Endocrinology 137 (1996) 4796-4805
18. Franca L.R., Silva Jr. V.A., Chiarini-Garcia H., Garcia S.K., and Debeljuk L. Cell proliferation and hormonal changes during postnatal development of the testis in the pig. Biol. Reprod. 63 (2000) 1629-1636
19. Hess R.A. Estrogen in the adult male reproductive tract: a review. Reprod. Biol. Endocrinol. 1 (2003) 52
20. Holtz W., and Smidt D. The fertilizing capacity of epididymal spermatozoa in the pig. J. Reprod. Fertil. 46 (1976) 227-229
21. Joshi H.S., and Raeside J.I. Synergistic effects of testosterone and oestrogens on accessory sex glands and sexual behaviour of the boar. J. Reprod. Fertil. 33 (1973) 411-423
22. Korenman S.G., Stevens R.H., Carpenter L.A., Robb M., Niswender G.D., and Sherman B.M. Estradiol radioimmunoassay without chromatography: procedure, validation and normal values. J. Clin. Endocrinol. Metab. 38 (1974) 718-720
23. Kuiper G.G., Enmark E., Pelto-Huikko M., Nilsson S., and Gustafsson J.A. Cloning of a novel receptor expressed in rat prostate and ovary. Proc. Natl. Acad. Sci. U.S.A. 93 (1996) 5925-5930
24. Linfor J., and Berger T. Potential role of alphav and beta1 integrins as oocyte adhesion molecules during fertilization in pigs. J. Reprod. Fertil. 120 (2000) 65-72
25. McCarthy M.J., At-Taras E.E., Pearl C.A., Nitta-Oda B.S., Roser J.F., Conley A.J., and Berger T. Suppression of endogenous estrogen during development affects porcine epididymal sperm maturation. Mol. Reprod. Dev. 73 (2006) 1122-1128
26. McCoard S.A., Lunstra D.D., Wise T.H., and Ford J.J. Specific staining of Sertoli cell nuclei and evaluation of Sertoli cell number and proliferative activity in Meishan and White Composite boars during the neonatal period. Biol. Reprod. 64 (2001) 689-695
27. O'Donnell L., Robertson K.M., Jones M.E., and Simpson E.R. Estrogen and spermatogenesis. Endocr. Rev. 22 (2001) 289-318
28. Oliveira C.A., Carnes K., Franca L.R., Hermo L., and Hess R.A. Aquaporin-1 and -9 are differentially regulated by oestrogen in the efferent ductule epithelium and initial segment of the epididymis. Biol. Cell 97 (2005) 385-395
29. Pelletier G., and El-Alfy M. Immunocytochemical localization of estrogen receptors alpha and beta in the human reproductive organs. J. Clin. Endocrinol. Metab. 85 (2000) 4835-4840
30. Pelletier G., Luu-The V., Charbonneau A., and Labrie F. Cellular localization of estrogen receptor beta messenger ribonucleic acid in cynomolgus monkey reproductive organs. Biol. Reprod. 61 (1999) 1249-1255
31. Perez-Pe R., Cebrian-Perez J.A., and Muino-Blanco T. Semen plasma proteins prevent cold-shock membrane damage to ram spermatozoa. Theriogenology 56 (2001) 425-434
32. Prins G.S., Birch L., Couse J.F., Choi I., Katzenellenbogen B., and Korach K.S. Estrogen imprinting of the developing prostate gland is mediated through stromal estrogen receptor alpha: studies with alphaERKO and betaERKO mice. Cancer Res. 61 (2001) 6089-6097
33. Prins G.S., Marmer M., Woodham C., Chang W., Kuiper G., Gustafsson J.A., and Birch L. Estrogen receptor-beta messenger ribonucleic acid ontogeny in the prostate of normal and neonatally estrogenized rats. Endocrinology 139 (1998) 874-883
34. Pursel V.G., Johnson L.A., and Schulman L.L. Effect of dilution, seminal plasma and incubation period on cold shock susceptibility of boar spermatozoa. J. Anim. Sci. 37 (1973) 528-531
35. Putra D.K., and Blackshaw A.W. Quantitative studies of compensatory testicular hypertrophy following unilateral castration in the boar. Aust. J. Biol. Sci. 38 (1985) 429-434
36. Ramesh R., Pearl C.A., At-Taras E., Roser J.F., and Berger T. Ontogeny of androgen and estrogen receptor expression in porcine testis: effect of reducing testicular estrogen synthesis. Anim. Reprod. Sci. 102 (2007) 286-299
37. Risbridger G.P., and Taylor R.A. Physiology of the male accessory sex structures: the prostate gland, seminal vesicles, and bulbourethral glands. In: Neill J.D. (Ed). Knobil and Neill's Physiology of Reproduction (2006), Elsevier, San Diego 1149-1171
38. Rochira V., Balestrieri A., Madeo B., Spaggiari A., and Carani C. Congenital estrogen deficiency in men: a new syndrome with different phenotypes; clinical and therapeutic implications in men. Mol. Cell. Endocrinol. 193 (2002) 19-28
39. Saunders P.T. Oestrogen receptor beta (ER beta). Rev. Reprod. 3 (1998) 164-171
40. Setchell B.P., Laurie M.S., Flint A.P., and Heap R.B. Transport of free and conjugated steroids from the boar testis in lymph, venous blood and rete testis fluid. J. Endocrinol. 96 (1983) 127-136
41. Smith E.P., Boyd J., Frank G.R., Takahashi H., Cohen R.M., Specker B., Williams T.C., Lubahn D.B., and Korach K.S. Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man. N. Engl. J. Med. 331 (1994) 1056-1061
42. Zhou Q., Clarke L., Nie R., Carnes K., Lai L.W., Lien Y.H., Verkman A., Lubahn D., Fisher J.S., Katzenellenbogen B.S., and Hess R.A. Estrogen action and male fertility: roles of the sodium/hydrogen exchanger-3 and fluid reabsorption in reproductive tract function. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 14132-14137