Impaired body weight and tail length gain and altered bone quality after treatment with the aromatase inhibitor exemestane in male rats

Hormone Research in Paediatrics

Volumn 73, Issue 5, 2010, Pages 376-385

  Van Gool, Sandy A ^a   Wit, Jan M ^a   De Schutter, Tineke ^d   De Clerck, Nora ^d   Postnov, Andreï A ^d   Kremer Hovinga, Sandra ^a   Van Doorn, Jaap ^b   Veiga, Sergio J ^e   Garcia Segura, Luis Miguel ^e   Karperien, Marcel ^c  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c UNIVERSITY OF TWENTE   (Netherlands)

^d UNIVERSITY OF ANTWERP   (Belgium)

^e INSTITUTO CAJAL   (Spain)

Author keywords

Aromatase; Aromatase inhibition; Estrogen; Growth; Growth plate maturation; Osteopenia; Rat model; Sexual dimorphism

Indexed keywords

AROMATASE; EXEMESTANE; PLACEBO;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; GROWTH PLATE; HISTOPATHOLOGY; LIVER; MALE; NONHUMAN; ORGAN WEIGHT; OSTEOPENIA; PRIORITY JOURNAL; RAT; SEMINAL VESICLE; TAIL; TESTIS; WEIGHT REDUCTION;

ANDROSTADIENES; ANIMALS; AROMATASE INHIBITORS; BODY WEIGHT; BONE AND BONES; BONE DENSITY; BONE DISEASES, METABOLIC; GROWTH PLATE; MALE; RATS; RATS, WISTAR; TAIL; X-RAY MICROTOMOGRAPHY;

EID: 77954058402     PISSN: 16632818     EISSN: 16632826     Source Type: Journal    
DOI: 10.1159/000308171     Document Type: Article

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