Doxycycline up-regulates the expression of IL-6 and GM-CSF via MAPK/ERK and NF-κB pathways in mouse thymic epithelial cells

International Immunopharmacology

Volumn 11, Issue 9, 2011, Pages 1143-1149

  Huang, Ying ^a   Li, Rong ^b,c   Chen, Xun ^a   Zhuo, Ya ^a   Jin, Rong ^b   Qian, Xiao Ping ^b   Jiang, Yan Qiu ^a   Zeng, Zi Han ^a   Zhang, Yu ^b   Shao, Qi Xiang ^a  

^a JIANGSU UNIVERSITY   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^c NANCHANG UNIVERSITY   (China)

Author keywords

Cytokine; Doxycycline; MAPK; NF B; Thymic epithelial cells

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; BETA ACTIN; DOXYCYCLINE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR RELA;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; EPITHELIUM CELL; GENE EXPRESSION REGULATION; MICROENVIRONMENT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; THYMIC EPITHELIAL CELL; THYMOCYTE; UPREGULATION; WESTERN BLOTTING;

ANIMALS; BUTADIENES; CELL LINE; DOXYCYCLINE; EPITHELIAL CELLS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; INTERLEUKIN-6; MAP KINASE KINASE 1; MAP KINASE KINASE 2; MAP KINASE SIGNALING SYSTEM; MICE; NF-KAPPA B; NITRILES; PHOSPHORYLATION; RNA, MESSENGER; SULFONES; THYMOCYTES; TRANSCRIPTION FACTOR RELA; UP-REGULATION;

EID: 80051909548     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2011.03.011     Document Type: Article

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