Effect of murine thymic epithelial cell line (MTEC1) on the functional expression of CD4+CD8- thymocyte subgroups

International Immunology

Volumn 12, Issue 8, 2000, Pages 1127-1133

  Ge, Q ^a   Chen, W F ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

CD4+CD8 thymocyte subgroup; Cytokine; Proliferation; Thymic stromal cells

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CONCANAVALIN A; CYTOKINE;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CELL ISOLATION; CELL LINE; CELL MATURATION; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EPITHELIUM CELL; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SPLEEN; STROMA CELL; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; TH2 CELL; THYMOCYTE;

EID: 0033862064     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/12.8.1127     Document Type: Article

References (28)

1. Natural and engineered disorders of lymphocyte development
2. Intrathymic T cell receptor (TCR) targeting in mice lacking CD4 or major histocompatibility complex (MHC) class II rescue of CD4 T cell lineage without coengagement of TCR/CD4 by MHC class II
3. Timing and casting for actors of thymic negative selection
4. A molecular map of T cell development
5. Thymic cortical epithelium is sufficient for the development of mature T cells in relB-deficient mice
6. Negative selection in the thymus includes semimature T cells
7. Quantitative impact of clonal deletion on the T cell repertoire
8. Development, organization and function of the thymic medulla in normal, immunodeficient or autoimmune mice
9. Thymic emigration: Conveyor belts or lucky dips
10. - thymocytes are functionally immature
11. - thymocyte subsets that differ in their maturation level, lyymphokine secretion, and selection patterns
12. Activation events during thymic selection
13. + T cells acquire specific lymphokine secretion potentials during thymic maturation
14. - thymocytes lacking the heat-stable antigen
15. + T cell subsets defined
16. + T-cell subsets
17. - thymocytes induced by medullary-type thymus epithelial cells
18. + cells
19. + single-positive thymocytes requires the thymus to produce long-lived, functional T cells
20. Down regulation of CD1 marks acquisition of functional maturation of human thymocytes and defines a control point in late stages of human T cell development
21. - thymocytes and its implication in the late stage of thymocyte development
22. Multiple types of cytokines constitutively produced by an established murine thymic epithelial cell line
23. + mature thymocytes require different post-selection processing for final development
24. + mature thymocytes
25. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
26. Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between T(h)1 and T(h)2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies
27. TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
28. Purified protein derivative of Mycobacterium tuberculosis and excretory-secretory antigen (s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production