Matrix metalloproteinases inhibition provides neuroprotection against hypoxia-ischemia in the developing brain

Journal of Neurochemistry

Volumn 111, Issue 3, 2009, Pages 726-736

  Chen, Wanqiu ^a   Hartman, Richard ^b   Ayer, Robert ^a   Marcantonio, Suzanne ^a   Kamper, Joel ^b   Tang, Jiping ^a   Zhang, John H ^a  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOMA LINDA UNIVERSITY   (United States)

Author keywords

Blood brain barrier; Hypoxic ischemic; Matrix metalloproteinase; Neonatal

Indexed keywords

CELL PROTEIN; DOXYCYCLINE; EVANS BLUE; GELATINASE A; GELATINASE B; ILOMASTAT; IMMUNOGLOBULIN G; MATRIX METALLOPROTEINASE; OXYGEN; TIGHT JUNCTION PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; ATTENUATION; BEHAVIOR; BLOOD BRAIN BARRIER; BODY WEIGHT; BRAIN ATROPHY; BRAIN DEVELOPMENT; BRAIN EDEMA; BRAIN ISCHEMIA; BRAIN TISSUE; BRAIN WATER; CAROTID ARTERY LIGATION; CLINICAL EVALUATION; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; DRUG MEGADOSE; ENZYME INHIBITION; FEMALE; IMMUNOHISTOCHEMISTRY; LOW DRUG DOSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; WESTERN BLOTTING; ZYMOGRAPHY;

ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; ATROPHY; BLOOD-BRAIN BARRIER; BRAIN EDEMA; DIPEPTIDES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HYPOXIA-ISCHEMIA, BRAIN; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MAZE LEARNING; MEMBRANE PROTEINS; METALLOENDOPEPTIDASES; NEUROPROTECTIVE AGENTS; PHOSPHOPROTEINS; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASE-2;

RATTUS;

EID: 70349904406     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06362.x     Document Type: Article

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