메뉴 건너뛰기




Volumn 47, Issue 13, 2011, Pages 2042-2051

Apigenin affects leptin/leptin receptor pathway and induces cell apoptosis in lung adenocarcinoma cell line

Author keywords

Apigenin; Apoptosis; Leptin; Lung cancer; Pleural fluids; Proliferation; ROS

Indexed keywords

APIGENIN; LEPTIN; LEPTIN RECEPTOR; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; RECOMBINANT LEPTIN;

EID: 80051908679     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2011.03.034     Document Type: Article
Times cited : (48)

References (30)
  • 1
    • 44249086425 scopus 로고    scopus 로고
    • Non-small cell lung cancer: Epidemiology, risk factors, treatment, and survivorship
    • DOI 10.4065/83.5.584
    • J.R. Molina, P. Yang, S.D. Cassivi, S.E. Schild, and A.A. Adjei Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship Mayo Clin Proc 83 2008 584 594 (Pubitemid 351720831)
    • (2008) Mayo Clinic Proceedings , vol.83 , Issue.5 , pp. 584-594
    • Molina, J.R.1    Yang, P.2    Cassivi, S.D.3    Schild, S.E.4    Adjei, A.A.5
  • 2
    • 0033003511 scopus 로고    scopus 로고
    • Food, nutrition, and the prevention of cancer: A global perspective. American Institute for Cancer Research/World Cancer Research Fund, American Institute for Cancer Research, 1997
    • M.J. Glade Food, nutrition, and the prevention of cancer: a global perspective. American Institute for Cancer Research/World Cancer Research Fund, American Institute for Cancer Research, 1997 Nutrition 15 1999 523 526
    • (1999) Nutrition , vol.15 , pp. 523-526
    • Glade, M.J.1
  • 3
    • 12844272321 scopus 로고    scopus 로고
    • Polyphenols and disease risk in epidemiologic studies
    • I.C. Arts, and P.C. Hollman Polyphenols and disease risk in epidemiologic studies Am J Clin Nutr 81 1 Suppl. 2005 317S 325S
    • (2005) Am J Clin Nutr , vol.81 , Issue.1 SUPPL.
    • Arts, I.C.1    Hollman, P.C.2
  • 5
    • 0032856994 scopus 로고    scopus 로고
    • Induction of apoptosis by apigenin and related flavonoids through cytochrome c release and activation of caspase-9 and caspase-3 in leukaemia HL-60 cells
    • I.K. Wang, S.Y. Lin-Shiau, and J.K. Lin Induction of apoptosis by apigenin and related flavonoids through cytochrome c release and activation of caspase-9 and caspase-3 in leukaemia HL-60 cells Eur J Cancer 35 1999 1517 1525
    • (1999) Eur J Cancer , vol.35 , pp. 1517-1525
    • Wang, I.K.1    Lin-Shiau, S.Y.2    Lin, J.K.3
  • 6
    • 20444403798 scopus 로고    scopus 로고
    • Apoptotic pathways are inhibited by leptin receptor activation in neutrophils
    • A. Bruno, S. Conus, I. Schimd, and H.U. Simon Apoptotic pathways are inhibited by leptin receptor activation in neutrophils J Immunol 174 2005 8090 8096 (Pubitemid 40806320)
    • (2005) Journal of Immunology , vol.174 , Issue.12 , pp. 8090-8096
    • Bruno, A.1    Conus, S.2    Schmid, I.3    Simon, H.-U.4
  • 7
    • 56449092185 scopus 로고    scopus 로고
    • Elevated serum leptin levels: A risk factor for non-small-cell lung cancer?
    • A. Terzidis, T.N. Sergentanis, and G. Antonopoulos Elevated serum leptin levels: a risk factor for non-small-cell lung cancer? Oncology 76 2009 19 25
    • (2009) Oncology , vol.76 , pp. 19-25
    • Terzidis, A.1    Sergentanis, T.N.2    Antonopoulos, G.3
  • 9
    • 76149142449 scopus 로고    scopus 로고
    • Leptin and adiponectin: New players in the field of tumour cell and leucocyte migration
    • K. Lang, and J. Ratke Leptin and adiponectin: new players in the field of tumour cell and leucocyte migration Cell Commun Signal 23 2009 7 27
    • (2009) Cell Commun Signal , vol.23 , pp. 7-27
    • Lang, K.1    Ratke, J.2
  • 12
    • 56649086772 scopus 로고    scopus 로고
    • Critical role of the NADPH oxidase subunit p47phox on vascular TLR expression and neointimal lesion formation in high-fat diet-induced obesity
    • J.X. Chen, and A. Stinnett Critical role of the NADPH oxidase subunit p47phox on vascular TLR expression and neointimal lesion formation in high-fat diet-induced obesity Lab Invest 88 2008 1316 1328
    • (2008) Lab Invest , vol.88 , pp. 1316-1328
    • Chen, J.X.1    Stinnett, A.2
  • 13
    • 77953646802 scopus 로고    scopus 로고
    • Leptin modulates innate and adaptive immune cell recruitment after cigarette smoke exposure in mice
    • J.H. Vernooy, K.R. Bracke, and N.E. Drummen Leptin modulates innate and adaptive immune cell recruitment after cigarette smoke exposure in mice J Immunol 184 2010 7169 7177
    • (2010) J Immunol , vol.184 , pp. 7169-7177
    • Vernooy, J.H.1    Bracke, K.R.2    Drummen, N.E.3
  • 14
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • DOI 10.1006/abio.1987.9999
    • P. Chomczynski, and N. Sacchi Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction Anal Biochem 162 1987 156 159 (Pubitemid 17064313)
    • (1987) Analytical Biochemistry , vol.162 , Issue.1 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 15
    • 44949231424 scopus 로고    scopus 로고
    • T method
    • DOI 10.1038/nprot.2008.73, PII NPROT.2008.73
    • T.D. Schmittgen, and K.J. Livak Analyzing real-time PCR data by the comparative C(T) method Nat Protoc 3 2008 1101 1108 (Pubitemid 351818697)
    • (2008) Nature Protocols , vol.3 , Issue.6 , pp. 1101-1108
    • Schmittgen, T.D.1    Livak, K.J.2
  • 16
    • 78650712158 scopus 로고    scopus 로고
    • Altered CD94/NKG2A and perforin expression reduce the cytotoxic activity in malignant pleural effusions
    • E. Pace, C. Di Sano, and M. Ferraro Altered CD94/NKG2A and perforin expression reduce the cytotoxic activity in malignant pleural effusions Eur J Cancer 47 2011 296 304
    • (2011) Eur J Cancer , vol.47 , pp. 296-304
    • Pace, E.1    Di Sano, C.2    Ferraro, M.3
  • 18
    • 77953189137 scopus 로고    scopus 로고
    • Apigenin: A promising molecule for cancer prevention
    • S. Shukla, and S. Gupta Apigenin: a promising molecule for cancer prevention Pharm Res 27 2010 962 978
    • (2010) Pharm Res , vol.27 , pp. 962-978
    • Shukla, S.1    Gupta, S.2
  • 19
    • 77951564322 scopus 로고    scopus 로고
    • Apigenin induces caspase-dependent apoptosis in human lung cancer A549 cells through Bax- and Bcl-2-triggered mitochondrial pathway
    • H.F. Lu, Y.J. Chie, and M.S. Yang Apigenin induces caspase-dependent apoptosis in human lung cancer A549 cells through Bax- and Bcl-2-triggered mitochondrial pathway Int J Oncol 36 2010 1477 1484
    • (2010) Int J Oncol , vol.36 , pp. 1477-1484
    • Lu, H.F.1    Chie, Y.J.2    Yang, M.S.3
  • 20
    • 33644926465 scopus 로고    scopus 로고
    • Flavonoids inhibit melanoma lung metastasis by impairing tumour cells endothelium interactions
    • M. Piantelli, C. Rossi, and M. Iezzi Flavonoids inhibit melanoma lung metastasis by impairing tumour cells endothelium interactions J Cell Physiol 207 2006 23 29
    • (2006) J Cell Physiol , vol.207 , pp. 23-29
    • Piantelli, M.1    Rossi, C.2    Iezzi, M.3
  • 21
    • 44649105662 scopus 로고    scopus 로고
    • Dietary xenoestrogens differentially impair 3T3-L1 preadipocyte differentiation and persistently affect leptin synthesis
    • P. Phrakonkham, S. Viengchareun, and C. Belloir Dietary xenoestrogens differentially impair 3T3-L1 preadipocyte differentiation and persistently affect leptin synthesis J Steroid Biochem Mol Biol 110 2008 95 103
    • (2008) J Steroid Biochem Mol Biol , vol.110 , pp. 95-103
    • Phrakonkham, P.1    Viengchareun, S.2    Belloir, C.3
  • 22
    • 0242610804 scopus 로고    scopus 로고
    • The Chemopreventive Bioflavonoid Apigenin Modulates Signal Transduction Pathways in Keratinocyte and Colon Carcinoma Cell Lines
    • R. Van Dross, Y. Xue, A. Knudson, and J.C. Pelling The chemopreventive bioflavonoid apigenin modulates signal transduction pathways in keratinocyte and colon carcinoma cell lines J Nutr 133 2003 3800S 3804S (Pubitemid 37392603)
    • (2003) Journal of Nutrition , vol.133 , Issue.SUPPL. 1
    • Van Dross, R.1    Xue, Y.2    Knudson, A.3    Pelling, J.C.4
  • 23
    • 70349481110 scopus 로고    scopus 로고
    • Apigenin-induced apoptosis is mediated by reactive oxygen species and activation of ERK1/2 in rheumatoid fibroblast-like synoviocytes
    • G.C. Shin, C. Kim, and J.M. Lee Apigenin-induced apoptosis is mediated by reactive oxygen species and activation of ERK1/2 in rheumatoid fibroblast-like synoviocytes Chem Biol Interact 182 2009 29 36
    • (2009) Chem Biol Interact , vol.182 , pp. 29-36
    • Shin, G.C.1    Kim, C.2    Lee, J.M.3
  • 24
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • Z. Xia, M. Dickens, J. Raingeaud, R.J. Davis, and M.E. Greenberg Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis Science 270 1995 1326 1331
    • (1995) Science , vol.270 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3    Davis, R.J.4    Greenberg, M.E.5
  • 25
    • 77950590629 scopus 로고    scopus 로고
    • The attenuation of MG132, a proteasome inhibitor, induced A549 lung cancer cell death by p38 inhibitor in ROS-independent manner
    • Y.H. Han, H.J. Moon, B.R. You, and W.H. Park The attenuation of MG132, a proteasome inhibitor, induced A549 lung cancer cell death by p38 inhibitor in ROS-independent manner Oncol Res 18 2010 315 322
    • (2010) Oncol Res , vol.18 , pp. 315-322
    • Han, Y.H.1    Moon, H.J.2    You, B.R.3    Park, W.H.4
  • 26
    • 32444433202 scopus 로고    scopus 로고
    • Free radicals, metals and antioxidants in oxidative stress-induced cancer
    • DOI 10.1016/j.cbi.2005.12.009, PII S0009279705004333
    • M. Valko, C.J. Rhodes, J. Moncol, M. Izakovic, and M. Mazur Free radicals, metals and antioxidants in oxidative stress-induced cancer Chem Biol Interact 160 2006 1 40 (Pubitemid 43227479)
    • (2006) Chemico-Biological Interactions , vol.160 , Issue.1 , pp. 1-40
    • Valko, M.1    Rhodes, C.J.2    Moncol, J.3    Izakovic, M.4    Mazur, M.5
  • 28
    • 0029918901 scopus 로고    scopus 로고
    • Role of oxygen free radicals in cancer development
    • D. Dreher, and A.F. Junod Role of oxygen free radicals in cancer development Eur J Cancer 32A 1996 30 38
    • (1996) Eur J Cancer , vol.32 A , pp. 30-38
    • Dreher, D.1    Junod, A.F.2
  • 29
    • 36849068883 scopus 로고    scopus 로고
    • Induction of apoptotic cell death by synthetic naringenin derivatives in human lung epithelial carcinoma A549 cells
    • E.R. Lee, Y.J. Kang, and H.Y. Choi Induction of apoptotic cell death by synthetic naringenin derivatives in human lung epithelial carcinoma A549 cells Biol Pharm Bull 30 2007 2394 2398
    • (2007) Biol Pharm Bull , vol.30 , pp. 2394-2398
    • Lee, E.R.1    Kang, Y.J.2    Choi, H.Y.3
  • 30
    • 76749120379 scopus 로고    scopus 로고
    • Chrysanthemum morifolium Ramat. reduces the oxidised LDL-induced expression of intercellular adhesion molecule-1 and E-selectin in human umbilical vein endothelial cells
    • C.K. Lii, Y.P. Lei, and H.T. Yao Chrysanthemum morifolium Ramat. reduces the oxidised LDL-induced expression of intercellular adhesion molecule-1 and E-selectin in human umbilical vein endothelial cells J Ethnopharmacol 128 2010 213 220
    • (2010) J Ethnopharmacol , vol.128 , pp. 213-220
    • Lii, C.K.1    Lei, Y.P.2    Yao, H.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.